Colloid or crystalloid in the resuscitation of hemorrhagic shock: a controlled clinical trial.

Abstract:

:The object of this article is to assess the value of human serum albumin (HSA) in the initial resuscitation of hypotensive trauma victims. Thirty-six patients (mean age = 30 years) in shock from trauma who underwent laparotomies were randomly assigned to either Ringer's lactate solution (RL) resuscitation or 4% HSA in RL resuscitation. Both groups received approximately 8L of test fluid and 6U of washed red cells. The only death in the study occurred in a patient assigned to the RL group. Two patients in each group required mechanical ventilation for longer than 24 hours. No differences were noted in a battery of pulmonary function tests performed daily for 5 days. These results demonstrate that HSA is not essential in this clinical setting for safe and effective resuscitation.

journal_name

Surgery

journal_title

Surgery

authors

Moss GS,Lowe RJ,Jilek J,Levine HD

subject

Has Abstract

pub_date

1981-04-01 00:00:00

pages

434-8

issue

4

eissn

0039-6060

issn

1532-7361

journal_volume

89

pub_type

临床试验,杂志文章,随机对照试验

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