Vascular complications associated with pancreaticoduodenectomy adversely affect clinical outcome.

Abstract:

BACKGROUND:Early survival after pancreaticoduodenectomy has improved, but its morbidity remains high. The purpose of this study is to determine how the intra-operative (OR) occurrence of major vascular complications affects the outcome of pancreaticoduodenectomy. METHODS:The medical records of 180 consecutive patients having pancreaticoduodenectomy from 1991 to 2001 were reviewed. Vascular complications were defined as "an unanticipated injury or thrombosis of a major vessel necessitating intervention." Age, sex, type of pancreaticoduodenectomy, tumor size, estimated blood loss, OR time, time in intensive care, post-OR hospitalization, and survival were compared. RESULTS:Eighteen vascular complications were identified. Differences in age, sex, and type of resection between patients with or without vascular complications were not significant. OR time, estimated blood loss, blood transfusions, tumor size, time in intensive care, and post-OR hospitalization were all significantly greater in patients with vascular complications. Median survival for patients with vascular complications was significantly shorter than for patients without vascular complications. Thirty-day mortality was greater in patients with vascular complications. CONCLUSION:Vascular complications significantly affect the outcome of pancreaticoduodenectomy increasing OR time, estimated blood loss, blood transfusion requirements, time in intensive care, post-OR hospitalization, and mortality.

journal_name

Surgery

journal_title

Surgery

authors

Kim AW,McCarthy WJ 3rd,Maxhimer JB,Quiros RM,Hollinger EF,Doolas A,Millikan KW,Deziel DJ,Godellas CV,Prinz RA

doi

10.1067/msy.2002.127688

subject

Has Abstract

pub_date

2002-10-01 00:00:00

pages

738-44; discussion 744-7

issue

4

eissn

0039-6060

issn

1532-7361

pii

S0039606002001551

journal_volume

132

pub_type

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