Abstract:
OBJECTIVE:We describe patient characteristics and postoperative morbidity and mortality rates for patients with Down syndrome undergoing congenital heart disease surgery. METHODS:This retrospective cohort study used the Society of Thoracic Surgeons Congenital Heart Surgery Database to compare patient characteristics and postoperative outcomes for patients (0-18 years) with or without Down syndrome who underwent surgery in 2000-2008. RESULTS:A total of 45,579 patients (4350 patients with Down syndrome and 41,229 without Down syndrome) were included (median age: 7 months [interquartile range [IQR]: 47 days to 4 years]; 56% male). Patients with Down syndrome were younger at surgery, with the exception of those undergoing tetralogy of Fallot repair or atrioventricular septal defect repair. Mortality rates for patients with or without Down syndrome did not differ significantly. Lengths of stay were prolonged for patients with Down syndrome undergoing atrial septal defect closure (median: 4 days [IQR: 3-5 days] vs 3 days [IQR: 2-4 days]; P < .0001), ventricular septal defect closure (median: 5 days [IQR: 4-8 days] vs 4 days [IQR: 3-6 days]; P < .0001), or tetralogy of Fallot repair (7 days [IQR: 5-10 days] vs 6 days [IQR: 5-9 days]; P < .001) and were associated with postoperative respiratory and infectious complications. Patients with Down syndrome undergoing ventricular septal defect closure had a higher rate of heart block requiring pacemaker placement (2.9% vs 0.8%; P < .0001). CONCLUSION:In this large, contemporary cohort, Down syndrome did not confer a significant mortality risk for the most common operations; however, postoperative morbidity remained common.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Fudge JC Jr,Li S,Jaggers J,O'Brien SM,Peterson ED,Jacobs JP,Welke KF,Jacobs ML,Li JS,Pasquali SKdoi
10.1542/peds.2009-3245subject
Has Abstractpub_date
2010-08-01 00:00:00pages
315-22issue
2eissn
0031-4005issn
1098-4275pii
peds.2009-3245journal_volume
126pub_type
杂志文章相关文献
PEDIATRICS文献大全abstract::An epidemic of acute myositis affecting children occurred in association with influenza B infections. The myositis followed the initial influenza-like episode, and almost exclusively involved the gastrocnemius and soleus muscles. Patients improved without specific treatment and made a complete recovery in four to five...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1976-02-01 00:00:00
abstract::With a randomized clinical trial, the possibility was assessed that a tracheal instillation of pulmonary surfactant prior to the first breath might prevent the development of some of the signs of neonatal respiratory distress syndrome. Of the 72 infants in the trial, all born at a gestational age of less than 30 weeks...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1985-08-01 00:00:00
abstract:OBJECTIVE:There is concern that high-deductible health plans may have negative effects on vulnerable groups. The objective of this study was to compare the characteristics of families who have children and switch to high-deductible health plans with those who stay in traditional plans. METHODS:This double-cohort study...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2008-1738
更新日期:2009-04-01 00:00:00
abstract:OBJECTIVE:Current American Academy of Pediatrics and United States Public Health Service Immunization Practices Advisory Committee recommendations for hepatitis B immunization in premature infants weighing <2 kg at birth born to hepatitis B surface antigen (HBSAg)-negative mothers are to delay the initiation of vaccina...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.103.2.e14
更新日期:1999-02-01 00:00:00
abstract:UNLABELLED:Because late repair of coarctation of the aorta (COA) is associated with premature cardiovascular disease in adult life, early detection and treatment is important. OBJECTIVES:To determine the timing of referral to see whether early detection of COA has improved in the past decade, to evaluate the pattern o...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract::Idiopathic acute eosinophilic pneumonia is a rare and potentially life-threatening condition that is defined by bilateral pulmonary infiltrates and fever in the presence of pulmonary eosinophilia. It often presents acutely in previously healthy individuals and can be difficult to distinguish from infectious pneumonia....
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2019-3007
更新日期:2020-04-01 00:00:00
abstract:OBJECTIVES:To determine the proportion of youth meeting national recommendations for food group intake and to identify food intake patterns. DESIGN:The US Department of Agriculture's 1989-1991 Continuing Surveys of Food Intakes by Individuals were used to estimate food intake. Intake was determined from 3 days of diet...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.100.3.323
更新日期:1997-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Recent data suggest that cow's milk allergy (CMA) has become more persistent, prolonging treatment via strict elimination of cow's milk products into a period of skeletal growth. The objectives of this study were to compare bone mineral density (BMD), vitamin D status, and dietary intakes of c...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2015-1742
更新日期:2016-05-01 00:00:00
abstract::We present a 6-week-old male infant with persistent hyperbilirubinemia, hypertriglyceridemia, elevated creatine kinase levels, and transaminitis since the second week of life. When he developed hyperkalemia, clinical suspicion was raised for adrenal insufficiency despite hemodynamic stability. A full endocrine workup ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2016-1479
更新日期:2017-07-01 00:00:00
abstract::To assess the prevalence of growth problems among school entrants in an urban population who were not preselected on poverty or other nutritional risk criteria, we analyzed height and weight measurements for 5170 4- and 5-year-old children (91.9% black, 5.5% white, and 2.6% Hispanic) who enrolled in District of Columb...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1990-05-01 00:00:00
abstract::In 24% (18 out of 76) small-for-dates a "significant" though asymptomatic hypoglycemia was demonstrated during the first six hours of life. The cord blood glucose concentration was lower in the hypoglycemic compared to that of the small-for-date normoglycemic group. In the hypoglycemic infants, the disappearance rate ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1976-07-01 00:00:00
abstract::The improved survival of very low-birth-weight infants, who require prolonged hospitalization and many invasive procedures, increases the risks for nosocomial illnesses, such as disseminated fungal infections. In a 2-year period, systemic fungal infections were clinically diagnosed in ten infants. This necessitated th...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1984-02-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to compare the frequency of risk behaviors and to measure the extent of co-occurrence of these behaviors in chronically ill and healthy adolescents. METHODS:Data were drawn from the 2002 Swiss Multicenter Adolescent Survey on Health database, a nationally representative survey...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2008-1479
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVE:We investigated whether the duration and exclusivity of breastfeeding affects the likelihood of gross and fine motor delay in infants and examined the effect of factors that might explain any observed differences. METHODS:The study sample included all term singleton infants who weighed > 2500 g at birth and ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-3141
更新日期:2006-09-01 00:00:00
abstract:OBJECTIVES:Media Detective is a 10-lesson elementary school substance use prevention program developed on the basis of the message interpretation processing model designed to increase children's critical thinking skills about media messages and reduce intent to use tobacco and alcohol products. The purpose of this stud...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1542/peds.2010-0068
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVE:To investigate the association between neonatal hyperbilirubinemia and autism spectrum disorders (ASD). METHODS:We conducted a large case-control study nested within the cohort of singleton term infants born between 1995 and 1998 at a northern California Kaiser Permanente hospital. Case subjects (n = 338) we...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2004-1870
更新日期:2005-02-01 00:00:00
abstract::Schools are in a uniquely favorable position to increase physical activity and fitness among their students. This policy statement reaffirms the American Academy of Pediatrics' support for the efforts of schools to include increased physical activity in the curriculum, suggests ways in which schools can meet their goa...
journal_title:Pediatrics
pub_type: 指南,杂志文章,实务指引
doi:10.1542/peds.105.5.1156
更新日期:2000-05-01 00:00:00
abstract::A retrospective analysis of bone scans of 381 children with unexplained skeletal pain was made. Of these, findings are reported on 358 for whom there were sufficient clinical data. The bone scan results suggested trauma as the cause of pain in 43 patients, inflammatory disease in 73 patients, and neoplasia in ten pati...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1987-04-01 00:00:00
abstract:BACKGROUND:Disparities in health service use have been described across a range of sociodemographic factors. Patterns of PICU use have not been thoroughly assessed. METHODS:This was a population-level, retrospective analysis of admissions to the Cincinnati Children's Hospital Medical Center PICU between 2011 and 2016....
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2019-0748
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Concerns about vaccine safety have led some parents to decline recommended vaccination of their children, leading to the resurgence of diseases. Reassurance of vaccine safety remains critical for population health. This study systematically reviewed the literature on the safety of routine vaccines recommende...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2014-1079
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVES:The National Survey of Early Childhood Health (NSECH) is a new survey that was designed to provide nationally representative data on the health and development of children and to fill an information gap in the pediatric literature on parents' views of the delivery of health care to their young children. DES...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:2004-06-01 00:00:00
abstract::Increased hair loss a few months after delivering an infant is a common postpartum condition known as telogen effluvium. A much less common condition involving young infants is the hair-thread tourniquet syndrome, or toe tourniquet syndrome, which involves hair or thread becoming so tightly wrapped around an appendage...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.111.3.685
更新日期:2003-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Physicians have a major influence on parental vaccine decisions. We tested a physician-targeted communication intervention designed to (1) reduce vaccine hesitancy in mothers of infants seen by trained physicians and (2) increase physician confidence in communicating about vaccines. METHODS:W...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2014-3199
更新日期:2015-07-01 00:00:00
abstract:OBJECTIVE:The prevalence of autism spectrum disorder is steadily increasing and placing more demands on already overburdened diagnostic and treatment systems. A thoughtful, systematic reorganization of autism service delivery may reduce delays and better meet the growing need. METHODS:Two clinical centers in the Autis...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2015-2851M
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVE:Depression is common among adolescents, but rates increase significantly in the presence of chronic health conditions. Outpatient screening for depression is recommended but rarely formally conducted due to barriers of implementation. METHODS:To provide a model for depression screening of youth with chronic ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2013-0681
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVE:Pacifier use has been reported to be associated with a reduced risk of sudden infant death syndrome (SIDS), but most countries around the world, including the United States, have been reluctant to recommend the use of pacifiers because of concerns about possible adverse effects. This meta-analysis was underta...
journal_title:Pediatrics
pub_type: 杂志文章,meta分析
doi:10.1542/peds.2004-2631
更新日期:2005-11-01 00:00:00
abstract:OBJECTIVE:To test the effect of nonnutritive sucking (NNS), music therapy (MT), and combined NNS and MT (NNS + MT), versus no intervention, on heart rate, transcutaneous oxygen (TcPaO(2)) levels, and pain behavior of neonates in intensive care units having blood taken by a heel-stick procedure. METHODOLOGY:A within-su...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章
doi:10.1542/peds.105.4.e49
更新日期:2000-04-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of antenatal phenobarbital (PB) therapy on neonatal intracranial hemorrhage (ICH) in preterm infants. DESIGN:Prospective, randomized, controlled trial. SETTING:Single institution study. SUBJECTS AND INTERVENTIONS:Women in preterm labor ( < 35 weeks' gestation) were assigned to contro...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1996-05-01 00:00:00
abstract::This is a summary of the presentation on airway clearance in neuromuscular disorders presented as part of the program on airway clearance in Duchenne muscular dystrophy at the 30th annual Carrell-Krusen Neuromuscular Symposium on February 20, 2008. ...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2008-2952G
更新日期:2009-05-01 00:00:00
abstract::In this prospective, longitudinal study, the relative impact of intracranial hemorrhage and prolonged mechanical ventilation on developmental progress during the first 18 months of life of infants weighing 1,200 g or less at birth was examined. A total of 159 surviving infants were divided into two groups: infants wit...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1987-05-01 00:00:00