Sex Differences in Long-term Metabolic Effects of Maternal Resveratrol Intake in Adult Rat Offspring.

abstract：:The potential role of basic fibroblast growth factor (bFGF) as a mediator of cell-cell interactions in the growth and development of the testis was examined. Nuclease protection analysis was used to evaluate bFGF gene expression in the testis and other male reproductive tract tissues. bFGF expression was evident in se...

journal_title：Endocrinology

authors： Mullaney BP,Skinner MK

更新日期：1992-12-01 00:00:00

abstract：:GnRH is expressed in first-trimester human placenta and increases cell invasion in extravillous cytotrophoblasts (EVTs). Invasive phenotypes have been reported to be regulated by transcription factor activator protein 1 (AP-1) and mesenchymal cadherin-11. The aim of our study was to investigate the roles of AP-1 compo...

journal_title：Endocrinology

authors： Peng B,Zhu H,Ma L,Wang YL,Klausen C,Leung PC

更新日期：2015-06-01 00:00:00

abstract：:A RT-PCR approach was used to clone and sequence the full-length growth hormone receptor (GHR) of a teleost fish, the turbot (Scophthalmus maximus). Total liver RNA was amplified by RT-PCR with degenerate primers designed in extracellular and cytoplasmic regions, and a single DNA fragment of 1100 bp was obtained. The ...

journal_title：Endocrinology

authors： Calduch-Giner J,Duval H,Chesnel F,Boeuf G,Pérez-Sánchez J,Boujard D

更新日期：2001-07-01 00:00:00

abstract：:cAMP is involved in the regulation of secretory activity in lactotrope, thyrotrope, and gonadotrope cells. The present study examined whether pulsatile or intermittent changes in cAMP are more effective than a continuous stimulation in increasing pituitary hormone gene expression. Pituitaries from adult female rats we...

journal_title：Endocrinology

authors： Haisenleder DJ,Yasin M,Marshall JC

更新日期：1992-12-01 00:00:00

abstract：:Basal or hypothalamic extract-induced ACTH or TSH secretory capacity as well as intracellular ACTH content were assessed in cultured rat adenohypophyseal cells after various pretreatments of the donor animals. Medium and intracellular ACTH or TSH were measured by radioimmunoassay. Ten-day to 2-month adrenalectomy enha...

journal_title：Endocrinology

authors： Yasuda N,Takebe K,Greer MA

更新日期：1976-03-01 00:00:00

abstract：:Oxytocin (OT) is released by the posterior pituitary during male orgasm and is supposed to participate in the ejaculatory process. We now report evidence demonstrating the presence of an OT receptor gene (real-time RT-PCR and Northern blot) and protein (immunohistochemistry, Western blot, and binding studies) expressi...

journal_title：Endocrinology

authors： Vignozzi L,Filippi S,Luconi M,Morelli A,Mancina R,Marini M,Vannelli GB,Granchi S,Orlando C,Gelmini S,Ledda F,Forti G,Maggi M

更新日期：2004-04-01 00:00:00

abstract：:Atrial natriuretic factor (ANF) was studied for its effect on renin release by rat renal cortical slices. ANF (rat) alone (10(-9)-10(-6) M) had no effect on basal renin release, but significantly (P less than 0.001) potentiated angiotensin II (AII) inhibition of renin secretion in doses as low as 10(-9) M. ANF also po...

journal_title：Endocrinology

authors： Antonipillai I,Vogelsang J,Horton R

更新日期：1986-07-01 00:00:00

abstract：:Bisphosphonates are effective for preventing and treating skeletal disorders associated with hyperresorption. Their safety and efficacy has been studied in adults where the growth plate is fused and there is no longitudinal bone growth and little appositional growth. Although bisphosphonate use in the pediatric popula...

journal_title：Endocrinology

authors： Zhu ED,Louis L,Brooks DJ,Bouxsein ML,Demay MB

更新日期：2014-04-01 00:00:00

abstract：:A 50-70% depletion in the anterior pituitary concentration of PRL occurred within 5 min of electrical stimulation of a single abdominal mammary nerve of urethane-anesthetized lactating rats previously nonsuckled for 6-8 h. The stimulus parameters were: 1-msec pulses, 10-20/sec at 5-30 V applied 5 sec on and 10 sec off...

journal_title：Endocrinology

authors： Mena F,Pacheco P,Grosvenor CE

更新日期：1980-02-01 00:00:00

abstract：:Skeletal cells synthesize bone morphogenetic proteins (BMPs) and BMP antagonists. Gremlin, a BMP antagonist, is expressed in osteoblasts and opposes BMP effects on osteoblastic differentiation and function in vitro. However, its effects in vivo are not known. To investigate the actions of gremlin on bone remodeling in...

journal_title：Endocrinology

authors： Gazzerro E,Pereira RC,Jorgetti V,Olson S,Economides AN,Canalis E

更新日期：2005-02-01 00:00:00

abstract：:In previous studies we found that plasma angiotensinogen levels were reduced by lesions of the hypothalamic paraventricular nuclei. To determine if the decrease was caused by decreased secretion of hormones that normally stimulate angiotensinogen secretion by the liver, we correlated the changes in plasma angiotensino...

journal_title：Endocrinology

authors： Kjos T,Gotoh E,Tkacs N,Shackelford R,Ganong WF

更新日期：1991-08-01 00:00:00

abstract：:The interaction of alloxan and cyclic AMP on glucose-induced insulin secretion was studied with the use of isolated rat islet perifusion. Simultaneous perifusion with cyclic AMP and alloxan did not protect the islets against the effect of alloxan. However, addition of dibutyryl cyclic AMP to the alloxan solution produ...

journal_title：Endocrinology

authors： Tomita T,Scarpelli DG

更新日期：1977-05-01 00:00:00

abstract：:There are now robust data supporting the Developmental Origins of Health and Disease (DOHaD) paradigm. This includes human and animal data focusing on nutrition or environmental chemicals during development. However, the term DOHaD has not been generally accepted as the official term to be used when one is concerned w...

journal_title：Endocrinology

authors： Heindel JJ,Balbus J,Birnbaum L,Brune-Drisse MN,Grandjean P,Gray K,Landrigan PJ,Sly PD,Suk W,Cory Slechta D,Thompson C,Hanson M

更新日期：2015-10-01 00:00:00

abstract：:The importance of thyroid hormone (TH) in wound healing is not well understood. To gain insight, we evaluated the impact of TH deficiency on wound-healing genes in cultured keratinocytes. By RT-PCR, keratin 6a (K6a) and 16 (K16) gene expression in TH replete cells was 3.8- (P < 0.005) and 1.9-fold (P < 0.05) greater, ...

journal_title：Endocrinology

authors： Safer JD,Crawford TM,Holick MF

更新日期：2004-05-01 00:00:00

abstract：:New insulin-secreting cell lines (INS-1 and INS-2) were established from cells isolated from an x-ray-induced rat transplantable insulinoma. The continuous growth of these cells was found to be dependent on the reducing agent 2-mercaptoethanol. Removal of this thiol compound caused a 15-fold drop in total cellular glu...

journal_title：Endocrinology

authors： Asfari M,Janjic D,Meda P,Li G,Halban PA,Wollheim CB

更新日期：1992-01-01 00:00:00

abstract：:IGF1-a small, single-chain, secreted peptide in mammals-is essential for normal somatic growth and is involved in a variety of other physiological and pathophysiological processes. IGF1 expression appears to be controlled by several different signaling mechanisms in mammals, with GH playing a key role by activating an...

journal_title：Endocrinology

authors： Rotwein P

更新日期：2018-06-01 00:00:00

abstract：:Progestins have been implicated in breast cancer development, yet a role for progesterone (Pg) in ductal morphogenesis (DM) has not been established. To determine whether Pg could cause DM, we compared relative effects of Pg, estradiol (E2) and IGF-I on anatomical and molecular biological parameters of IGF-I-related D...

journal_title：Endocrinology

authors： Ruan W,Monaco ME,Kleinberg DL

更新日期：2005-03-01 00:00:00

abstract：:As a model of the changes in peripheral iodothyronine metabolism that occur during ontogeny, we have studied the metabolism of 125I-labeled T4 and several of its partially deiodinated derivatives by the liver of the chick embryo. Homogenates of livers obtained from chicks varying in embryonic age from 8 days to the ti...

journal_title：Endocrinology

authors： Borges M,LaBourene J,Ingbar SH

更新日期：1980-12-01 00:00:00

abstract：:For 3 yr, 1-yr synchronized circannual rhythms were found for the chick oviduct weights, amounts of soluble protein, concentrations of the progesterone receptor in this organ, and capacity of this steroid-receptor complex in cytosol in bind in vitro to deoxyribonucleoprotein acceptor sites. By fitting the data with 1-...

journal_title：Endocrinology

authors： Spelsberg TC,Halberg F

更新日期：1980-10-01 00:00:00

abstract：:The action of excitatory amino acid agonists on endogenous somatostatin release was examined in primary cultures of rat diencephalic neurons. Increasing concentrations of glutamate stimulated somatostatin release in a dose-dependent manner. Since this effect was decreased by Mg2+, all experiments were performed in Mg2...

journal_title：Endocrinology

authors： Tapia-Arancibia L,Astier H

更新日期：1988-11-01 00:00:00

abstract：:[14C]-3-O-Methyl-D-glucose transport in response to GH stimulation was measured in freshly prepared and cultured hepatocytes from hypophysectomized (hypox) adult female rats. Sugar transport in freshly isolated hepatocytes from hypox animals was stimulated by 10(-9) M human GH (hGH) and 10(-9) M rat GH (rGH) during 0-...

journal_title：Endocrinology

authors： Fix JA,Moore WV

更新日期：1981-01-01 00:00:00

abstract：:The GH/IGF-I axis has both pre- and postpubertal metabolic effects. However, the differential effects of GH and/or IGF-I on animal physiology or the plasma proteome are still being unraveled. In this report, we analyzed several physiological effects along with the plasma proteome after treatment of mice with recombina...

journal_title：Endocrinology

authors： Ding J,List EO,Bower BD,Kopchick JJ

更新日期：2011-10-01 00:00:00

abstract：:3-Iodothyronamine (3-T 1 AM) and thyronamine (T AM) are novel endogenous signaling molecules that exhibit great structural similarity to thyroid hormones but apparently antagonize classical thyroid hormone (T(3)) actions. Their proposed biosynthesis from thyroid hormones would require decarboxylation and more or less ...

journal_title：Endocrinology

authors： Piehl S,Heberer T,Balizs G,Scanlan TS,Smits R,Koksch B,Köhrle J

更新日期：2008-06-01 00:00:00

abstract：:We recently reported that chronic 17β-estradiol (E2) treatment in mice decreases platelet responsiveness, prolongs the tail-bleeding time and protects against acute thromboembolism via the hematopoietic estrogen receptor alpha (ERα), and independently of ERβ. Here, we have explored the respective roles of membrane vs ...

journal_title：Endocrinology

authors： Valéra MC,Fontaine C,Lenfant F,Cabou C,Guillaume M,Smirnova N,Kim SH,Chambon P,Katzenellenbogen JA,Katzenellenbogen BS,Payrastre B,Arnal JF

更新日期：2015-11-01 00:00:00

abstract：:The existence of renin in a number of extrarenal tissues has been well documented, but the physiological role of extrarenal renin remains unknown. To study the physiological role of adrenal renin, we developed a serum-free culture system for adrenal capsular/zona glomrulosa explants. Explants showed good viability in ...

journal_title：Endocrinology

authors： Shier DN,Kusano E,Stoner GD,Franco-Saenz R,Mulrow PJ

更新日期：1989-07-01 00:00:00

abstract：:In granulosa cells derived from medium-sized porcine follicles, certain androgens have been shown to inhibit FSH-stimulated progesterone synthesis. To determine the site at which this inhibition takes place, the effects of androgens on FSH- and (Bu)2cAMP-stimulated pregnenolone and progesterone syntheses were examined...

journal_title：Endocrinology

authors： Lischinsky A,Evans G,Armstrong DT

更新日期：1983-12-01 00:00:00

abstract：:FSH promotes the differentiation of ovarian follicular granulosa cells via a cAMP-dependent mechanism. Based upon the presence of a prominent phospholipid/diolein/Ca2+-independent myelin basic protein kinase activity in soluble extracts of proliferating immature rat granulosa cells, we determine whether this activity ...

journal_title：Endocrinology

authors： Das S,Maizels ET,DeManno D,St Clair E,Adam SA,Hunzicker-Dunn M

更新日期：1996-03-01 00:00:00

abstract：:The mechanism of mitogen-activated protein kinase (MAPK, ERK) stimulation by the GnRH analog [D-Trp6]GnRH (GnRH-a) was investigated in the gonadotroph-derived alphaT3-1 cell line. GnRH-a as well as the protein kinase C (PKC) activator 12-O-tetradecanoyl phorbol-13-acetate (TPA) stimulated a sustained response of MAPK ...

journal_title：Endocrinology

authors： Reiss N,Llevi LN,Shacham S,Harris D,Seger R,Naor Z

更新日期：1997-04-01 00:00:00

abstract：:The influence of development and estrogen, thyroid hormone, corticosteroid, and fibrate administration on apolipoprotein (apo) A-IV mRNA levels in the liver and intestine and on serum or plasma concentrations of apo A-IV was studied in the rat. Treatment of ovariectomized rats with ethinyl estradiol provoked a dose-de...

journal_title：Endocrinology

authors： Staels B,van Tol A,Verhoeven G,Auwerx J

更新日期：1990-04-01 00:00:00

abstract：:In songbirds, singing behavior is controlled by a discrete network of interconnected brain nuclei known collectively as the song control system. Both the development of this system and the expression of singing behavior in adulthood are strongly influenced by sex steroid hormones. Although both androgenic and estrogen...

journal_title：Endocrinology

authors： Bernard DJ,Bentley GE,Balthazart J,Turek FW,Ball GF

更新日期：1999-10-01 00:00:00