Potential role of sugar transporters in cancer and their relationship with anticancer therapy.

abstract：:The presence of brown adipose tissue (BAT) in humans is unclear. Pheochromocytomas (PHEO) are rare tumors of neuroectodermal origin which occur in 0.1-0.2% of patients with hypertension. We sought to evaluate the presence and activity of BAT surrounding adrenal PHEO in a well-studied sample of 11 patients who were dia...

journal_title：International journal of endocrinology

authors： Iacobellis G,Di Gioia C,Petramala L,Chiappetta C,Serra V,Zinnamosca L,Marinelli C,Ciardi A,De Toma G,Letizia C

更新日期：2013-01-01 00:00:00

abstract：:Parathyroid glands contain the vitamin D receptor (VDR) and 25-hydroxyvitamin D-1α-hydroxylase (CYP27B1) and 24-hydroxylase (CYP24A1), which catalyze the production and degradation of 1,25-dihydroxyvitamin D [1,25(OH)2D], respectively. Previous studies have shown that the serum level of intact parathyroid hormone (iPT...

journal_title：International journal of endocrinology

authors： Jiang Y,Liao L,Li J,Wang L,Xie Z

更新日期：2020-04-09 00:00:00

abstract：:Objective. The follow-up of GH levels in short-stature children with pituitary hyperplasia secondary to primary hypothyroidism (PPH) is reported in a few cases. We aimed to observe changes in GH secretion in short-stature children with PPH. Methods. A total of 11 short-stature children with PPH accompanied by low GH l...

journal_title：International journal of endocrinology

authors： Liu M,Hu Y,Li G,Hu W

更新日期：2015-01-01 00:00:00

abstract：:Type 2 diabetes is characterized by frequent ectopic fat accumulation in several tissues and organs. In particular, a number of studies showed that these subjects frequently have hepatic fat accumulation, which may play a role in the metabolic abnormalities typical of diabetes and has been also linked to increased ris...

journal_title：International journal of endocrinology

authors： Bacchi E,Moghetti P

更新日期：2013-01-01 00:00:00

abstract：Objective:To identify the clinicopathological features correlated to lymph node metastasis (LNM) in patients with papillary thyroid microcarcinoma (PTMC). Methods:Clinical data of 785 PTMC patients who underwent surgical treatment at the Lishui Municipal Central Hospital from September 2008 to December 2017 were retro...

journal_title：International journal of endocrinology

authors： Cheng F,Chen Y,Zhu L,Zhou B,Xu Y,Chen Y,Wen L,Chen S

更新日期：2019-01-15 00:00:00

abstract：:The main purpose of our retrospective study was to evaluate the medical care of the patients with subclinical hypothyroidism (sHT) and to investigate the rationale for administering L-thyroxine (LT-4) to young sHT patients. Patients and Methods. Based on a retrospective review of the charts of 261 patients referred to...

journal_title：International journal of endocrinology

authors： Such K,Gawlik A,Dejner A,Wasniewska M,Zachurzok A,Antosz A,Gawlik T,Malecka-Tendera E

更新日期：2016-01-01 00:00:00

abstract：Objective:To evaluate the effectiveness and safety of coenzyme Q10 for patients with type 2 diabetes mellitus (T2DM). Methods:Data from randomized controlled trials were obtained to assess the effects of coenzyme Q10 versus placebo or western medicine on patients with T2DM. The study's registration number is CRD420180...

journal_title：International journal of endocrinology

authors： Zhang SY,Yang KL,Zeng LT,Wu XH,Huang HY

更新日期：2018-09-16 00:00:00

abstract：:Sestrin (SESN) is known as a cysteine sulfinic acid reductase. Recently, nonredox functions of SESN in metabolic regulation and antitumor property have been recognized. While mechanisms underlying the expression of SESN are not fully understood. Here we report that insulin markedly increased SESN2 level in HepG2 cells...

journal_title：International journal of endocrinology

authors： Chai D,Wang G,Zhou Z,Yang H,Yu Z

更新日期：2015-01-01 00:00:00

abstract：:Puerarin, the main isoflavone glycoside extracted from Radix Puerariae, is an isoflavone traditional Chinese herb. Previous studies have demonstrated that puerarin could regulate osteoblast proliferation and differentiation to promote bone formation. However, the effect of puerarin on the process of human osteoblasts ...

journal_title：International journal of endocrinology

authors： Liu LJ,Liu LQ,Bo T,Li SJ,Zhu Z,Cui RR,Mao DA

更新日期：2013-01-01 00:00:00

abstract：:Background. Abdominal obesity and its relative distribution are known to differ in association with metabolic characteristics and cardiorespiratory fitness. This study aimed to determine an association between fitness level and abdominal adiposity in overweight and obese adults. Methods. 228 overweight and obese indiv...

journal_title：International journal of endocrinology

authors： Kim S,Kim JY,Lee DC,Lee HS,Lee JW,Jeon JY

更新日期：2014-01-01 00:00:00

abstract：Aim:To clarify the contributions of fasting glucose (FG) and postprandial glucose (PG) to HbA1c in drug-naïve patients with type 2 diabetes (T2D) and impaired glucose tolerate (IGT)/impaired fasting glucose (IFG). Methods:Continuous glucose monitoring (CGM) was performed in 305 drug-naïve Chinese patients with T2D or ...

journal_title：International journal of endocrinology

authors： Yan R,Hu Y,Li F,Jiang L,Xu X,Wang J,Zhang Y,Ye L,Lee KO,Su X,Ma J

更新日期：2019-12-01 00:00:00

abstract：:The study explored the utility of four-point preprandial glucose self-monitoring to calculate several indices of glycemic control and variability in a study adding the DPP-4 inhibitor vildagliptin to ongoing insulin therapy. This analysis utilized data from a double-blind, randomized, placebo-controlled crossover stud...

journal_title：International journal of endocrinology

authors： Tura A,Farngren J,Schweizer A,Foley JE,Pacini G,Ahrén B

更新日期：2015-01-01 00:00:00

abstract：:Hyperparathyroidism-jaw tumor (HPT-JT) syndrome is an autosomal dominant disorder characterized by parathyroid tumors in association with fibro-osseous jaw tumors and uterine and renal lesions. HPT-JT syndrome is caused by germline mutations of the cell division cycle 73 (CDC73) gene that encodes the parafibromin, a 5...

journal_title：International journal of endocrinology

authors： Torresan F,Iacobone M

更新日期：2019-12-18 00:00:00

abstract：:The aim of this review was to summarize current knowledge on the correlation between depressive symptoms with a syndrome called partial androgen deficiency of the aging male (PADAM) and on the potential benefits of testosterone (T) treatment on mood. Despite, the causative nature of the relationship between low T leve...

journal_title：International journal of endocrinology

authors： Amore M,Innamorati M,Costi S,Sher L,Girardi P,Pompili M

更新日期：2012-01-01 00:00:00

abstract：:Preeclampsia is a serious medical problem affecting the mother and her child and influences their health not only during the pregnancy, but also many years after. Although preeclampsia is a subject of many research projects, the etiology of the condition remains unclear. One of the hypotheses related to the etiology o...

journal_title：International journal of endocrinology

authors： Kosicka K,Siemiątkowska A,Główka FK

更新日期：2016-01-01 00:00:00

abstract：:Aims. There are two phases of insulin secretion, the first (FPIS) and second phase (SPIS). In this study, we built equations to predict FPIS with metabolic syndrome (MetS) components and fasting plasma insulin (FPI). Methods. Totally, 186 participants were enrolled. 75% of participants were randomly selected as the st...

journal_title：International journal of endocrinology

authors： Lin JD,Hsu CH,Liang YJ,Lian WC,Hsieh CH,Wu CZ,Pei D,Chen YL

更新日期：2015-01-01 00:00:00

abstract：:Introduction. The mechanisms underlying the association between insulin resistance and intrahepatic lipid (IHL) accumulation are not completely understood. We sought to determine whether this association was explained by differences in fasting non-esterified fatty acid (NEFA) levels and/or NEFA suppression after oral ...

journal_title：International journal of endocrinology

authors： Finucane FM,Sharp SJ,Hatunic M,Sleigh A,De Lucia Rolfe E,Sayer AA,Cooper C,Griffin SJ,Savage DB,Wareham NJ

更新日期：2013-01-01 00:00:00

abstract：Objective:Neuroendocrine neoplasias (NENs) represent a rare and biologically heterogeneous group of malignancies. Treatment of NEN patients remains challenging due to lack of prospective evidence on the choice of ideal therapeutic sequence and therapeutic efficacy in specific individual scenarios. Methods:Clinical dat...

journal_title：International journal of endocrinology

authors： Mayer K,Kiry S,Yordanova A,Ahmadzadehfar H,Gaertner FC,Bundschuh RA,Essler M,Gonzalez-Carmona MA,Strassburg CP,Matthaei H,Lingohr P,Bisht S,Brossart P,Feldmann G

更新日期：2020-01-31 00:00:00

abstract：:The role of angiogenesis in pituitary tumor development has been questioned, as pituitary tumors have been usually found to be less vascularized than the normal pituitary tissue. Nevertheless, a significantly higher degree of vasculature has been shown in invasive or macropituitary prolactinomas when compared to nonin...

journal_title：International journal of endocrinology

authors： Cristina C,Luque GM,Demarchi G,Lopez Vicchi F,Zubeldia-Brenner L,Perez Millan MI,Perrone S,Ornstein AM,Lacau-Mengido IM,Berner SI,Becu-Villalobos D

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Evidence on the association between subclinical thyroid dysfunction and the risk of cardiovascular outcomes are conflicting. METHODS AND RESULTS:PubMed, EMbase, Web of Science, Cochrane Library, and China Biology Medicine (CBM) databases were searched from inception to July 10, 2016. A total of 16 studies w...

journal_title：International journal of endocrinology

authors： Sun J,Yao L,Fang Y,Yang R,Chen Y,Yang K,Tian L

更新日期：2017-01-01 00:00:00

abstract：:Objective. In pediatric central diabetes insipidus (CDI), etiology diagnosis and pituitary function monitoring are usually delayed. This study aimed to illustrate the importance of regular follow-up and pituitary function monitoring in pediatric CDI. Methods. The clinical, hormonal, and neuroradiological characteristi...

journal_title：International journal of endocrinology

authors： Liu W,Wang L,Liu M,Li G

更新日期：2016-01-01 00:00:00

abstract：:Despite 70 years of experience treating thyrotoxic patients with radioiodine not all patients are successfully treated by a single dose. Multiple factors predicting radioiodine efficacy have been reported. The aim of this study was to assess whether ethnicity was associated with radioiodine response. A retrospective r...

journal_title：International journal of endocrinology

authors： Tamatea JA,Conaglen JV,Elston MS

更新日期：2016-01-01 00:00:00

abstract：:Aim. To compare two creatinine-based estimated glomerular filtration rate (eGFR) equations, the chronic kidney disease epidemiology collaboration (CKD-EPI) and the modification of diet in renal disease (MDRD), for predicting the risk of CKD progression in type 2 diabetic patients with nephropathy. Methods. A total of ...

journal_title：International journal of endocrinology

authors： Lee EY,Lee YM,Choi KH,Lee HC,Lee BW,Kim BS

更新日期：2013-01-01 00:00:00

abstract：:Little published information is available regarding epidemiological data on vitamin D status in the large geographical region of Central Europe (CE). We searched the journal literature with regard to 25(OH)D concentrations among community-dwelling or healthy people living in CE. 25(OH)D concentrations varied by age, s...

journal_title：International journal of endocrinology

authors： Pludowski P,Grant WB,Bhattoa HP,Bayer M,Povoroznyuk V,Rudenka E,Ramanau H,Varbiro S,Rudenka A,Karczmarewicz E,Lorenc R,Czech-Kowalska J,Konstantynowicz J

更新日期：2014-01-01 00:00:00

abstract：:In the present study we evaluated in vivo and in vitro effects of 4-tert-octylphenol (OP) on the expression and distribution of adherens and gap junction proteins, N-cadherin, β -catenin, and connexin 43 (Cx43), in testes of seasonally breeding rodents, bank voles. We found that in bank vole testes expression and dist...

journal_title：International journal of endocrinology

authors： Hejmej A,Kotula-Balak M,Chojnacka K,Kuras P,Lydka-Zarzycka M,Bilinska B

更新日期：2013-01-01 00:00:00

abstract：:The study aimed at assessing the potential use of lower total and HMW adiponectin levels for predicting cardiovascular risk in patients with type 2 diabetes mellitus (T2DM). Concentrations of total adiponectin or high molecular weight (HMW) adiponectin decrease in association with the development of metabolic dysfunct...

journal_title：International journal of endocrinology

authors： Horáková D,Azeem K,Benešová R,Pastucha D,Horák V,Dumbrovská L,Martínek A,Novotný D,Švagera Z,Hobzová M,Galuszková D,Janout V,Doněvská S,Vrbková J,Kollárová H

更新日期：2015-01-01 00:00:00

abstract：:Pancreatic beta-cells, which secrete the hormone insulin, are the key arbiters of glucose homeostasis. Defective beta-cell numbers and/or function underlie essentially all major forms of diabetes and must be restored if diabetes is to be cured. Thus, the identification of the molecular regulators of beta-cell mass and...

journal_title：International journal of endocrinology

authors： Tarabra E,Pelengaris S,Khan M

更新日期：2012-01-01 00:00:00

abstract：:Primary hyperparathyroidism (PHPT) is not an uncommon disease in the western countries. In Thailand, on the contrary, PHPT was a rare condition with various clinical presentations. All 45 PHPT patients who underwent parathyroidectomy at the Department of Surgery, Siriraj Hospital during January 1997 and December 2007 ...

journal_title：International journal of endocrinology

authors： Prasarttong-Osoth P,Wathanaoran P,Imruetaicharoenchoke W,Rojananin S

更新日期：2012-01-01 00:00:00

abstract：:Prostate cancer (PCa) is the most common malignancy in elderly men. The progressive ageing of the world male population will further increase the need for tailored assessment and treatment of PCa patients. The determinant role of androgens and sexual hormones for PCa growth and progression has been established. Howeve...

journal_title：International journal of endocrinology

authors： Gacci M,Baldi E,Tamburrino L,Detti B,Livi L,De Nunzio C,Tubaro A,Gravas S,Carini M,Serni S

更新日期：2014-01-01 00:00:00

abstract：Objective:Once-weekly PEGylated recombinant human growth hormone (rhGH) is the sole long-acting GH formulation available currently for pediatric patients with GH deficiency (GHD). The aim of this study was to evaluate the efficacy and safety of PEGylated rhGH therapy compared to daily rhGH therapy in GHD children treat...

journal_title：International journal of endocrinology

authors： Qiao Y,Wang Z,Han J,Li G

更新日期：2019-09-19 00:00:00