A comparison of hepatitis B viral markers of patients in different clinical stages of chronic infection.

abstract：OBJECTIVE:Cholecystectomy is routinely performed at most transplant centers during living donor liver transplantation (LDLT). This study was performed to evaluate the feasibility of liver graft procurement with donor gallbladder preservation in LDLT. METHODS:Eighty-nine LDLTs (from June 2006 to Dec 2012) were retrospe...

journal_title：Hepatology international

authors： Dong JH,Ye S,Duan WD,Ji WB,Liang YR

更新日期：2015-10-01 00:00:00

abstract：:Solitary necrotic nodules of the liver occur rarely. Although these nodules are usually benign, they are surgically removed in most cases because they cannot be differentiated from malignant lesions. To date, the natural history of solitary fibrous nodules remains unclear. We present the case of an incidentally detect...

journal_title：Hepatology international

authors： Choi CS,Cho EY,Jeong JS,Im CJ,Yang BJ,Kim HC

更新日期：2010-07-29 00:00:00

abstract：:Immunomodulatory cell therapy as a complement to standard pharmacotherapy represents a novel approach to solid organ allograft acceptance. This methodology may allow for a reduced dose of immunosuppressive drug to be administered and thus attenuate the severe side effects associated with long-term immunosuppression su...

journal_title：Hepatology international

authors： Benseler V,Obermajer N,Johnson CL,Soeder Y,Dahlke MD,Popp FC

更新日期：2014-04-01 00:00:00

abstract：PURPOSE:The Asian Pacific Association for the Study of the Liver (APASL) convened an international working party to develop a consensus cost-effectiveness model for treatment of Hepatitis B in Asia Pacific countries in March 2010. METHODS:The working party consisted of expert hepatologists, virologists and epidemiolog...

journal_title：Hepatology international

authors： Dan YY,Wong JB,Hamid SS,Han KH,Jia JD,Liu CJ,Piratvisuth T,Lok AS,Lim SG

更新日期：2014-07-01 00:00:00

abstract：:Since their original identification, our understanding of the role of hepatic stellate cells in both health and disease continues to grow. Numerous studies have delineated the role of stellate cell activation in contributing to the pool of myofibroblasts responsible for liver fibrosis, and these have resulted in the d...

journal_title：Hepatology international

authors： Bansal MB

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Variceal bleeding is a major complication of portal hypertension, which is associated with significant mortality. Moreover, patients surviving a variceal bleeding episode have very high risk of rebleeding, which is associated with mortality as high as that of the first bleed. Because of this, prevention of b...

journal_title：Hepatology international

authors： Baiges A,Hernández-Gea V,Bosch J

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Early prediction of lamivudine (LAM) response by individualized monitoring of serum HBV DNA like roadmap concept, and investigation of the outcome after LAM discontinuation in renal transplant recipients (RTRs) with chronic hepatitis B (CHB). METHODS:We conducted a study on 19 RTRs with HBV infection receiv...

journal_title：Hepatology international

authors： Hu TH,Tsai MC,Chen YT,Chien YS,Hung CH,Chen TC,Tseng PL,Chang KC,Yen YH

更新日期：2012-04-01 00:00:00

abstract：PURPOSE:To evaluate the sequence variations in the enhancer II (EnhII)/basal core promotor (BCP)/precore (PC) and X genes of hepatitis B virus (HBV) in Thai patients with hepatocellular carcinoma (HCC) by conducting a cross-sectional case-control study. METHODS:As much as 60 patients with HCC and 60 patients without H...

journal_title：Hepatology international

authors： Tangkijvanich P,Sa-Nguanmoo P,Mahachai V,Theamboonlers A,Poovorawan Y

更新日期：2010-07-31 00:00:00

abstract：:Hepatitis due to hepatitis B virus reactivation after cytotoxic or immunosuppressive therapy is a serious cause of liver-related morbidity and mortality. With the characterization of the underlying pathogenesis, much progress in the management of this important clinical problem has been made in the past 2 decades. By ...

journal_title：Hepatology international

authors： Lau GK

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Coronavirus disease 2019 (COVID-19) pandemic is ongoing. Except for lung injury, it is possible that COVID-19 patients develop liver injury. Thus, we conducted a systematic review and meta-analysis to explore the incidence, risk factors, and prognosis of abnormal liver biochemical tests in COVID-19 ...

journal_title：Hepatology international

authors： Wu Y,Li H,Guo X,Yoshida EM,Mendez-Sanchez N,Levi Sandri GB,Teschke R,Romeiro FG,Shukla A,Qi X

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:Clevudine 30 mg showed potent antiviral activity with a marked post-treatment antiviral effect. However, long-term treatment with clevudine monotherapy induced resistance and myopathy in some cases. The objective of this study is to evaluate the preliminary efficacy and safety of the combination of clevudine 20...

journal_title：Hepatology international

authors： Tak WY,Yang JM,Kim BI,Baik SK,Cheon GJ,Byun KS,Kim DY,Yoo BC

更新日期：2014-05-25 00:00:00

abstract：BACKGROUND:The aim of our study was to explore how C1QTNF1-AS1 regulated miR-221-3p/SOCS3 axis in human hepatocellular carcinoma (HCC). METHODS:Differentially expressed lncRNAs and genes were examined via RNA-seq. GO analysis and KEGG pathway enrichment analysis were carried out based on the function of dys-regulated ...

journal_title：Hepatology international

authors： Li H,Zhang B,Ding M,Lu S,Zhou H,Sun D,Wu G,Gan X

更新日期：2019-05-01 00:00:00

abstract：PURPOSE:Microvascular invasion of hepatocellular carcinoma (HCC) is considered a poor prognostic factor of liver resection (LR) and liver transplantation (LT), but its significance for lesions within the up-to-7 criteria is unclear. This study investigated the survival benefit of primary LT against LR for HCC with micr...

journal_title：Hepatology international

authors： Chan SC,Fan ST,Chok KS,Cheung TT,Chan AC,Fung JY,Poon RT,Lo CM

更新日期：2011-10-21 00:00:00

abstract：:Spontaneous bacterial peritonitis (SBP) is a common cause of morbidity and mortality in patients with advanced cirrhosis and portal hypertension. While gram-negative rods and Enterococcus species are the common offending organisms, Salmonella has also been recognized as a rare and atypical offending organism. Atypical...

journal_title：Hepatology international

authors： Rajekar H,Wai CT,Lee KH,Wong SY,Tan KC

更新日期：2008-09-01 00:00:00

abstract：:Primary biliary cholangitis (PBC), previously known as primary biliary cirrhosis, is an autoimmune liver disease characterized by progressive destruction of small intrahepatic bile ducts. If left untreated, PBC may eventually result in end-stage liver disease. For better management of PBC and optimal allocation of med...

journal_title：Hepatology international

authors： Chen S,Duan W,You H,Jia J

更新日期：2017-09-01 00:00:00

abstract：:Primary sclerosing cholangitis (PSC) is a rare cholestatic liver disease, characterized by multiple strictures and dilatations of the intra- and extrahepatic bile ducts, leading to progressive liver fibrosis, in 10-15% cholangiocarcinoma, and ultimately end-stage liver disease. The pathogenesis is poorly understood, b...

journal_title：Hepatology international

authors： Prokopič M,Beuers U

更新日期：2020-12-30 00:00:00

abstract：PURPOSE:Lamivudine treatment of chronic hepatitis B (CHB) is associated with frequent resistance and loss of clinical benefit. We present outcomes of lamivudine-refractory Japanese patients treated with entecavir for 3 years. METHODS:Eighty-two patients refractory to lamivudine therapy received entecavir 0.5 or 1 mg d...

journal_title：Hepatology international

authors： Karino Y,Toyota J,Kumada H,Katano Y,Izumi N,Kobashi H,Sata M,Moriyama M,Imazeki F,Kage M,Ishikawa H,Masaki N,Seriu T,Omata M

更新日期：2010-02-06 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is a common malignant tumor with high lethality, and the hepatitis B virus (HBV) is a chief cause. HBV can accelerate HCC via multiple mechanisms. First, HBV induces immune reactions that lead to repeated hepatic inflammation, fibrosis and a deficient immune microenvironment. Subsequentl...

journal_title：Hepatology international

authors： Wang M,Xi D,Ning Q

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Initial presentation of hepatocellular carcinoma (HCC) at an advanced stage in patients under a regular surveillance program is a devastating problem. AIMS:We assessed the prevalence and factors associated with this surveillance failure. METHODS:A total of 304 HCC patients who received regular surveillance...

journal_title：Hepatology international

authors： Sinn DH,Yi J,Choi MS,Choi D,Gwak GY,Paik YH,Lee JH,Koh KC,Paik SW,Yoo BC

更新日期：2013-10-01 00:00:00

abstract：:NAFLD is a spectrum of liver disease starting with fatty liver at one end of the spectrum and cirrhosis or liver cancer at the other end. Worldwide, NAFLD has become one of the most common liver diseases and it has also become one of the leading indications for liver transplantation. Our understanding of the NAFLD epi...

journal_title：Hepatology international

authors： Alukal JJ,Thuluvath PJ

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Although clinical and experimental studies have demonstrated a correlation between obstructive jaundice and the development of sepsis, the mechanism has not been fully elucidated. PURPOSE:The aim of this study was to investigate the influence of biliary obstruction on bacterial translocation as a possible s...

journal_title：Hepatology international

authors： Abdeldayem H,Ghoneim E,Refaei AA,Abou-Gabal A

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND AND AIM:Acute kidney injury (AKI), as defined by the Acute Kidney Injury Network, has been widely investigated in decompensated liver cirrhosis patients. AKI is frequently progressive and independently associated with mortality in these patients. However, in the Asia-Pacific region, the majority of cases of ...

journal_title：Hepatology international

authors： Huang Z,Lin C,Fang J,Wang N,Zhou R,Pan C

更新日期：2015-07-01 00:00:00

abstract：:Duodenal varices are a rare complication in patients with portal hypertension. Bleeding from duodenal varices often results in a severe prognosis. Diagnosis of the disease is usually based on findings obtained by endoscopy or angiography. However, it occasionally fails to detect the lesion and demonstrate its porto-sy...

journal_title：Hepatology international

authors： Yoshida S,Watabe H,Akahane M,Kyoden Y,Ishikawa H,Yamada A,Sugimoto T,Ohta M,Ogura K,Yamaji Y,Ohtomo K,Kokudo N,Koike K,Omata M

更新日期：2010-07-24 00:00:00

abstract：PURPOSE:Despite improvements in immunosuppressive therapy, acute cellular rejection (ACR) remains an important cause of graft loss in patients undergoing liver transplantation. Recently, associations between cytokine gene polymorphisms in recipients and the occurrence of ACR have been reported. However, most studies di...

journal_title：Hepatology international

authors： Kamei H,Masuda S,Nakamura T,Ishigami M,Fujimoto Y,Ogura Y,Oike F,Takada Y,Hamajima N

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND/PURPOSE:In Japan, there is a growing population of patients with chronic hepatitis C virus (HCV) infection who failed a direct-acting antiviral (DAA)-based regimen. In this Phase 3 study, we evaluated sofosbuvir-velpatasvir plus ribavirin in Japanese patients with genotype 1 or 2 HCV infection who previously...

journal_title：Hepatology international

authors： Izumi N,Takehara T,Chayama K,Yatsuhashi H,Takaguchi K,Ide T,Kurosaki M,Ueno Y,Toyoda H,Kakizaki S,Tanaka Y,Kawakami Y,Enomoto H,Ikeda F,Jiang D,De-Oertel S,McNabb BL,Camus G,Stamm LM,Brainard DM,McHutchison JG,M

更新日期：2018-07-01 00:00:00

abstract：:Portal hypertension develops as a result of increased intrahepatic vascular resistance often caused by chronic liver disease that leads to structural distortion by fibrosis, microvascular thrombosis, dysfunction of liver sinusoidal endothelial cells (LSECs), and hepatic stellate cell (HSC) activation. While the basic ...

journal_title：Hepatology international

authors： McConnell M,Iwakiri Y

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:The relationship between chronic hepatitis B virus (HBV) infection and fatty liver in patients remains unclear. Although high-fat diets-induced hepatic steatosis was proved to reduce HBV replication in transgenic mice, the interplay between HBV and fatty liver in immunocompetent mouse model is yet to be eluci...

journal_title：Hepatology international

authors： Hu D,Wang H,Wang H,Wang Y,Wan X,Yan W,Luo X,Ning Q

更新日期：2018-09-01 00:00:00

abstract：AIM:Tamibarotene is a synthetic retinoid expected to inhibit tumor-cell proliferation and to induce apoptosis by selective interaction with retinoic acid receptor α/β. We conducted an open-label phase I/II study to determine the maximum tolerated dose (MTD) and recommended dose (RD), and to evaluate the pharmacokinetic...

journal_title：Hepatology international

authors： Kanai F,Obi S,Fujiyama S,Shiina S,Tamai H,Mochizuki H,Koike Y,Imamura J,Yamaguchi T,Saida I,Yokosuka O,Omata M

更新日期：2014-01-01 00:00:00

abstract：:Background and aims The aims of this study were to evaluate a preventive effect on collateral venous circulation of long-term administration of propranolol in intrahepatic portal hypertensive rats. Methods Eighty-six Sprague-Dawley rats were allocated to two models of hepatic fibrosis, bile duct-ligated (BDL) induced ...

journal_title：Hepatology international

authors： Fizanne L,Régenet N,Wang J,Oberti F,Moal F,Roux J,Gallois Y,Michalak S,Calès P

更新日期：2008-12-01 00:00:00

abstract：PURPOSE:All previous studies reported the benefit of antibiotic prophylaxis in cirrhotic patients with either a mixture of nonvariceal and variceal bleeding or variceal bleeding alone. Reports on sole peptic ulcers bleeding are lacking. We aimed to assess the effect of antibiotic prophylaxis in cirrhotic patients with ...

journal_title：Hepatology international

authors： Yang SC,Wu KL,Wang JH,Lee CH,Kuo YH,Tai WC,Chen CH,Chiou SS,Lu SN,Hu TH,Changchien CS,Chuah SK

更新日期：2013-03-01 00:00:00