Abstract:
:Spontaneous bacterial peritonitis (SBP) is a common cause of morbidity and mortality in patients with advanced cirrhosis and portal hypertension. While gram-negative rods and Enterococcus species are the common offending organisms, Salmonella has also been recognized as a rare and atypical offending organism. Atypical features of Salmonella SBP include both its occurrence in cirrhotic patients with immunosuppressive state and its lack of typical neutroascitic response. Diagnosis is often delayed as it requires confirmation from ascitic fluid culture. We report a case of Salmonella SBP occurring in a patient with decompensated cryptogenic cirrhosis with concurrent low-grade non-Hodgkin lymphoma and prior treatment with rituximab. Physicians should be aware of the atypical presentation, especially in cirrhotic patients who are immunosuppressed.
journal_name
Hepatol Intjournal_title
Hepatology internationalauthors
Rajekar H,Wai CT,Lee KH,Wong SY,Tan KCdoi
10.1007/s12072-008-9087-9subject
Has Abstractpub_date
2008-09-01 00:00:00pages
388-9issue
3eissn
1936-0533issn
1936-0541journal_volume
2pub_type
杂志文章abstract:BACKGROUND:Although arterial stiffness has been reported to be associated with nonalcoholic fatty liver disease (NAFLD), previous studies have relied only on noninvasive assessments for the diagnosis of NAFLD. This study attempted to investigate the association of arterial stiffness with the histological severity of NA...
journal_title:Hepatology international
pub_type: 杂志文章
doi:10.1007/s12072-020-10108-z
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND AND AIMS:Coagulopathic bleeding risk prediction is challenging in decompensated cirrhosis (DC) by conventional assays. Viscoelastic tests (VETs) are likely to be more useful for assessing coagulation status in these patients. We investigated whether the VET (Sonoclot) parameters with fibrinogen could predict...
journal_title:Hepatology international
pub_type: 杂志文章
doi:10.1007/s12072-020-10036-y
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND AND AIMS:A discrepancy in virological and biochemical responses may occur throughout interferon-based therapy for hepatitis C virus (HCV). We aimed to explore the risk, associated factors, potential mechanisms, and impact on the treatment outcome of the discrepancy. SUBJECTS AND METHODS:Consecutive 496, chr...
journal_title:Hepatology international
pub_type: 杂志文章
doi:10.1007/s12072-012-9388-x
更新日期:2013-03-01 00:00:00
abstract::Immunomodulatory cell therapy as a complement to standard pharmacotherapy represents a novel approach to solid organ allograft acceptance. This methodology may allow for a reduced dose of immunosuppressive drug to be administered and thus attenuate the severe side effects associated with long-term immunosuppression su...
journal_title:Hepatology international
pub_type: 杂志文章
doi:10.1007/s12072-013-9509-1
更新日期:2014-04-01 00:00:00
abstract:PURPOSE:The diagnostic potential of hepatic stellate cells (HSCs) and γδT cells for patients with hepatocellular carcinoma (HCC) and their synergistic contributions to the prognosis of these patients have not yet been investigated. The aim of this study was to elucidate the prognostic value of these cells in HCC. METH...
journal_title:Hepatology international
pub_type: 杂志文章
doi:10.1007/s12072-019-09969-w
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:L-Asparaginase is a bacterial enzyme used in the treatment of acute lymphoblastic leukemia. In the ongoing U.S. Drug-Induced Liver Injury Network (DILIN) prospective study, standard and pegylated asparaginase were the most frequent cause of liver injury with jaundice among anti-cancer agents (8 of 40: 20%). ...
journal_title:Hepatology international
pub_type: 杂志文章
doi:10.1007/s12072-019-09971-2
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND AND OBJECT:The risk of occult HBV infection (OBI) in children whose mothers are HBV carriers has received more widespread attention, but there were few reports to focus on the children with HBsAg-positive parents. In this study, we aimed to investigate the prevalence of OBI in immunized children with HBsAg-p...
journal_title:Hepatology international
pub_type: 杂志文章
doi:10.1007/s12072-020-10055-9
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND AND AIMS:Status 1A patients are prioritized over end-stage liver disease (ESLD) for liver transplantation (LT). ESLD patients with high MELD may have higher waitlist mortality than Status 1A patients, and may require LT more urgently. METHODS:Using United Network for Organ Sharing registry data, we retrospe...
journal_title:Hepatology international
pub_type: 杂志文章
doi:10.1007/s12072-016-9735-4
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:To compare the efficacy of entecavir (ETV) monotherapy up to 4 years in nucleos(t)ide analog (NA)-experienced and -naïve subjects. METHODS:One hundred sixty NA-experienced and 282 naïve chronic hepatitis B patients who were treated with ETV were enrolled. Of the 160 NA-experienced patients, 49 had prior lamivu...
journal_title:Hepatology international
pub_type: 杂志文章
doi:10.1007/s12072-013-9440-5
更新日期:2013-07-01 00:00:00
abstract::In a country such as Japan with the average age of patients with chronic hepatitis C treated with antivirals sometimes well above 60 years, the standard combination therapy is not well tolerated. In this randomized, prospective, controlled trial, we investigated the efficacy of 24-week peginterferon α monotherapy for ...
journal_title:Hepatology international
pub_type: 杂志文章
doi:10.1007/s12072-009-9134-1
更新日期:2009-09-01 00:00:00
abstract::Along with the obesity epidemic, the prevalence of nonalcoholic fatty liver disease (NAFLD) has increased exponentially. The histological disease spectrum of NAFLD ranges from bland fatty liver (hepatic steatosis), to the concomitant presence of inflammation and ballooning which defines nonalcoholic steatohepatitis (N...
journal_title:Hepatology international
pub_type: 杂志文章,评审
doi:10.1007/s12072-015-9689-y
更新日期:2016-05-01 00:00:00
abstract:PURPOSE:To evaluate the recent topics of Ballloon-occluded retrograde trasnvenous obliteration(B-RTO). METHOD:We overviewed the recent scientific papers regarding B-RTO. RESULT:B-RTO is a treatment method for occluding varices retrogradely using a sclerosing agent under balloon occlusion of a major draining vein. It ...
journal_title:Hepatology international
pub_type: 杂志文章,评审
doi:10.1007/s12072-017-9813-2
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:The life cycle of hepatitis C virus (HCV) is tightly associated with host lipoprotein metabolic pathways. Apolipoprotein is present on the outer surface of lipoprotein particles and plays an important role in lipoprotein metabolism. We aimed to elucidate the influence of chronic HCV infection on serum apolip...
journal_title:Hepatology international
pub_type: 杂志文章
doi:10.1007/s12072-014-9572-2
更新日期:2014-10-01 00:00:00
abstract::Non-alcoholic fatty liver disease (NAFLD) is currently one of the leading forms of chronic liver disease, and its rising frequency worldwide has reached epidemic proportions. NAFLD, particularly its progressive variant NASH (non-alcoholic steatohepatitis), can lead to advanced fibrosis, cirrhosis, and HCC. The pathoph...
journal_title:Hepatology international
pub_type: 杂志文章,评审
doi:10.1007/s12072-018-9854-1
更新日期:2018-03-01 00:00:00
abstract::In patients with chronic hepatitis B (CHB), liver fibrosis assessment is essential not only for determining prognosis but also for identifying patients who should receive treatment. Liver biopsy is limited by its invasiveness and sampling error. To explore effective non-invasive methods for liver fibrosis assessment, ...
journal_title:Hepatology international
pub_type: 杂志文章
doi:10.1007/s12072-013-9439-y
更新日期:2013-06-01 00:00:00
abstract::Substantial advancements in the field of primary biliary cirrhosis (PBC) research have broadened our understanding of this enigmatic disease. Genome-wide studies have identified several new candidate genes involved in the immunoregulatory process, particularly those responsible for antigen presentation and lymphocyte ...
journal_title:Hepatology international
pub_type: 杂志文章
doi:10.1007/s12072-012-9362-7
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:Compositional changes of the gut microbiota are known to occur in patients with nonalcoholic fatty liver disease (NAFLD); however, the changes did not corroborate between the studies. We evaluated the gut microbiota between NAFLD and non-NAFLD participants, excluding the influence of obesity and sex in this ...
journal_title:Hepatology international
pub_type: 杂志文章
doi:10.1007/s12072-019-09987-8
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND AND AIMS:Ultrasonography is the most frequently used modality in surveillance for HCC among patients with chronic hepatitis C. However, the optimal surveillance interval is still controversial and the usefulness of supplementary tumor marker determination has not been confirmed. METHODS:A total of 243 cases...
journal_title:Hepatology international
pub_type: 杂志文章
doi:10.1007/s12072-009-9145-y
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND AND AIM:Acute kidney injury (AKI), as defined by the Acute Kidney Injury Network, has been widely investigated in decompensated liver cirrhosis patients. AKI is frequently progressive and independently associated with mortality in these patients. However, in the Asia-Pacific region, the majority of cases of ...
journal_title:Hepatology international
pub_type: 杂志文章
doi:10.1007/s12072-015-9636-y
更新日期:2015-07-01 00:00:00
abstract::To address the relationship between hepatitis B virus (HBV) endemicity and HBV-related liver diseases in Mexico. Research literature reporting on HBsAg and antibody to hepatitis B core antigen (anti-HBc) prevalence in Mexican study groups were searched in NLM Gateway, PubMed, IMBIOMED, and others. Weighted mean preval...
journal_title:Hepatology international
pub_type: 杂志文章
doi:10.1007/s12072-008-9115-9
更新日期:2009-06-01 00:00:00
abstract::Liver transplantation is a definitive therapy for patients with end-stage liver disease and cirrhosis, with improvement in survival and quality of life. Patients are carefully screened and selected for this modality of treatment to achieve maximum survival benefit. For example, a patient with hepatocellular carcinoma ...
journal_title:Hepatology international
pub_type: 杂志文章
doi:10.1007/s12072-016-9770-1
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Initial presentation of hepatocellular carcinoma (HCC) at an advanced stage in patients under a regular surveillance program is a devastating problem. AIMS:We assessed the prevalence and factors associated with this surveillance failure. METHODS:A total of 304 HCC patients who received regular surveillance...
journal_title:Hepatology international
pub_type: 杂志文章
doi:10.1007/s12072-013-9462-z
更新日期:2013-10-01 00:00:00
abstract:PURPOSE:Lamivudine treatment of chronic hepatitis B (CHB) is associated with frequent resistance and loss of clinical benefit. We present outcomes of lamivudine-refractory Japanese patients treated with entecavir for 3 years. METHODS:Eighty-two patients refractory to lamivudine therapy received entecavir 0.5 or 1 mg d...
journal_title:Hepatology international
pub_type: 杂志文章
doi:10.1007/s12072-009-9162-x
更新日期:2010-02-06 00:00:00
abstract::More than 170 million people worldwide are infected with hepatitis C virus (HCV). A characteristic of this virus is a high tendency toward chronic infection. Several factors affect the viral outcome after infection. Among them, HCV-specific CD4 T cells are thought to play a crucial role in controlling viremia. Cumulat...
journal_title:Hepatology international
pub_type: 杂志文章
doi:10.1007/s12072-011-9321-8
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND AND AIM:Cirrhosis is a controversial determinant of mortality in HBV-related acute-on-chronic liver failure (HBV-ACLF). The present study aimed to explore the effects of cirrhosis and the associated risk factors, especially its complications, on the outcome of HBV-ACLF. METHODS:A prospective-retrospective c...
journal_title:Hepatology international
pub_type: 杂志文章
doi:10.1007/s12072-019-09992-x
更新日期:2019-11-01 00:00:00
abstract::Reactive oxygen and nitrogen species (ROS and RNS) are produced by metabolism of normal cells. However, in liver diseases, redox is increased thereby damaging the hepatic tissue; the capability of ethanol to increase both ROS/RNS and peroxidation of lipids, DNA, and proteins was demonstrated in a variety of systems, c...
journal_title:Hepatology international
pub_type: 杂志文章
doi:10.1007/s12072-009-9158-6
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND AND AIM:Relationships between circulating microRNA-122 (miR-122) and histological features of nonalcoholic fatty liver disease (NAFLD) are unclear. METHODS:The impact of serum miR-122 levels for histological features and hepatocellular carcinoma (HCC) was investigated in 305 Japanese patients with histologi...
journal_title:Hepatology international
pub_type: 杂志文章
doi:10.1007/s12072-016-9729-2
更新日期:2016-07-01 00:00:00
abstract::Primary sclerosing cholangitis (PSC) is a rare cholestatic liver disease, characterized by multiple strictures and dilatations of the intra- and extrahepatic bile ducts, leading to progressive liver fibrosis, in 10-15% cholangiocarcinoma, and ultimately end-stage liver disease. The pathogenesis is poorly understood, b...
journal_title:Hepatology international
pub_type: 杂志文章,评审
doi:10.1007/s12072-020-10118-x
更新日期:2020-12-30 00:00:00
abstract::Chronic hepatitis B virus (HBV) infection is endemic in the Asian-Pacific region, and reactivation of HBV post-cancer chemotherapy has become an emerging clinical challenge. Patients with detectable serum HBV DNA before chemotherapy and those receiving intensive chemotherapy are particularly at a risk of HBV reactivat...
journal_title:Hepatology international
pub_type: 杂志文章
doi:10.1007/s12072-011-9279-6
更新日期:2013-06-01 00:00:00
abstract:PURPOSE:We investigated whether the combined presence and evolution of hepatitis B virus (HBV) mutant strains in the hepatitis B e antigen (HBeAg)-positive status can predict clinical outcomes after HBeAg seroconversion. METHODS:One hundred and eighty-six patients with spontaneous HBeAg seroconversion were enrolled in...
journal_title:Hepatology international
pub_type: 杂志文章
doi:10.1007/s12072-012-9381-4
更新日期:2013-06-01 00:00:00