当前位置： SCI文献检索 > Hepatology International期刊下所有文献 > Ultrasound surveillance for early detection of hepatocellular carcinoma among patients with chronic hepatitis C.

Ultrasound surveillance for early detection of hepatocellular carcinoma among patients with chronic hepatitis C.

Abstract：

BACKGROUND AND AIMS:Ultrasonography is the most frequently used modality in surveillance for HCC among patients with chronic hepatitis C. However, the optimal surveillance interval is still controversial and the usefulness of supplementary tumor marker determination has not been confirmed. METHODS:A total of 243 cases of naive HCC were detected among 1,431 patients with chronic hepatitis C under outpatient-based surveillance. The mode of HCC detection, including ultrasound surveillance interval, was retrospectively examined and the relation between the interval and detected tumor size was analyzed. Tumor volume doubling time was estimated from exponential increase in serum tumor marker levels when applicable. RESULTS:HCC was first detected by ultrasonography in 221 patients. Ultrasound surveillance interval, ranging between 2 and 8 months, was not correlated with the size of tumor at detection. Patients with cirrhosis were likely to be surveyed at shorter intervals. The size of tumor exceeded 30 mm only in three (1.4%) cases. They were all positive for a biomarker and the estimated tumor doubling time was short. In 14 cases, HCC was first detected by CT indicated by abnormal rise in tumor marker levels despite negative ultrasound findings. In the remaining eight cases, ultrasonography had been replaced by CT as surveillance modality because of excessive obesity or coarseness of liver parenchyma. CONCLUSIONS:Ultrasound surveillance at 6-month intervals was appropriate in general for the detection of HCC at a size smaller than 30 mm. However, in patient with established cirrhosis, more frequent screening would be needed to detect tumors of the same size.

journal_name

Hepatol Int

journal_title

Hepatology international

authors

Sato T,Tateishi R,Yoshida H,Ohki T,Masuzaki R,Imamura J,Goto T,Kanai F,Obi S,Kato N,Shiina S,Kawabe T,Omata M

doi

10.1007/s12072-009-9145-y

subject

Has Abstract

pub_date

2009-12-01 00:00:00

pages

544-50

issue

4

eissn

1936-0533

issn

1936-0541

journal_volume

3

pub_type

杂志文章

相关文献

Hepatology International文献大全
  • Management of primary sclerosing cholangitis and its complications: an algorithmic approach.

    abstract：:Primary sclerosing cholangitis (PSC) is a rare cholestatic liver disease, characterized by multiple strictures and dilatations of the intra- and extrahepatic bile ducts, leading to progressive liver fibrosis, in 10-15% cholangiocarcinoma, and ultimately end-stage liver disease. The pathogenesis is poorly understood, b...

    journal_title：Hepatology international

    pub_type： 杂志文章,评审

    doi：10.1007/s12072-020-10118-x

    authors： Prokopič M,Beuers U

    更新日期：2020-12-30 00:00:00

  • Feasibility of liver graft procurement with donor gallbladder preservation in living donor liver transplantation.

    abstract：OBJECTIVE:Cholecystectomy is routinely performed at most transplant centers during living donor liver transplantation (LDLT). This study was performed to evaluate the feasibility of liver graft procurement with donor gallbladder preservation in LDLT. METHODS:Eighty-nine LDLTs (from June 2006 to Dec 2012) were retrospe...

    journal_title：Hepatology international

    pub_type： 杂志文章

    doi：10.1007/s12072-015-9628-y

    authors： Dong JH,Ye S,Duan WD,Ji WB,Liang YR

    更新日期：2015-10-01 00:00:00

  • Dynamic changes of T cell receptor repertoires in patients with hepatitis B virus-related acute-on-chronic liver failure.

    abstract：BACKGROUND AND AIMS:T cell-mediated immune injury plays a critical role in the pathogenesis of hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF). Given the high short-term mortality and crucial role of T cells in the disease progression, it is necessary to investigate the dynamics of T cell clones dur...

    journal_title：Hepatology international

    pub_type： 杂志文章

    doi：10.1007/s12072-019-10008-x

    authors： Shen G,Sun S,Huang J,Deng H,Xu Y,Wang Z,Tang X,Gong X

    更新日期：2020-01-01 00:00:00

  • Existence of cancer stem cells in hepatocellular carcinoma: myth or reality?

    abstract：:The cancer stem cell (CSC) hypothesis has been disproved in many cancers. CSCs may exist in blood cancer, while many epithelial cancers may not have CSCs but tumor-initiating cells (TICs). Several independent studies have provided strong evidence for existence of CSCs in brain, skin, and colon cancers (Mani et al. in ...

    journal_title：Hepatology international

    pub_type： 杂志文章

    doi：10.1007/s12072-016-9777-7

    authors： Machida K

    更新日期：2017-03-01 00:00:00

  • Bacteroides in colonic mucosa-associated microbiota affects the development of minimal hepatic encephalopathy in patients with cirrhosis.

    abstract：BACKGROUND/PURPOSE:Gut microbiota has been associated with liver cirrhosis and, possibly, hepatic encephalopathy. However, only a few studies have examined the link between mucosa-associated microbiota (MAM) and minimal hepatic encephalopathy (MHE). Our aim was to investigate this relationship. METHODS:Twenty-four pat...

    journal_title：Hepatology international

    pub_type： 杂志文章

    doi：10.1007/s12072-019-09963-2

    authors： Haraguchi M,Miuma S,Masumoto H,Ichikawa T,Kanda Y,Sasaki R,Fukushima M,Miyaaki H,Taura N,Nakao K

    更新日期：2019-07-01 00:00:00

  • The influence of pioglitazone on the plasma amino acid profile in patients with nonalcoholic steatohepatitis (NASH).

    abstract：BACKGROUND AND AIMS:The peroxisome proliferator-activated receptor-γ (PPAR-γ) ligand, piglitazone, enhances the degradation of branched-chain amino acids (BCAAs) in adipose tissue. However, it remains unknown whether pioglitazone influences the plasma amino acids (AA) profile in patients with nonalcoholic steatohepatit...

    journal_title：Hepatology international

    pub_type： 杂志文章

    doi：10.1007/s12072-012-9395-y

    authors： Kakazu E,Kondo Y,Ninomiya M,Kimura O,Nagasaki F,Ueno Y,Shimosegawa T

    更新日期：2013-06-01 00:00:00

  • The effect of systemic antibiotic prophylaxis for cirrhotic patients with peptic ulcer bleeding after endoscopic interventions.

    abstract：PURPOSE:All previous studies reported the benefit of antibiotic prophylaxis in cirrhotic patients with either a mixture of nonvariceal and variceal bleeding or variceal bleeding alone. Reports on sole peptic ulcers bleeding are lacking. We aimed to assess the effect of antibiotic prophylaxis in cirrhotic patients with ...

    journal_title：Hepatology international

    pub_type： 杂志文章

    doi：10.1007/s12072-012-9378-z

    authors： Yang SC,Wu KL,Wang JH,Lee CH,Kuo YH,Tai WC,Chen CH,Chiou SS,Lu SN,Hu TH,Changchien CS,Chuah SK

    更新日期：2013-03-01 00:00:00

  • An open-label phase I/II study of tamibarotene in patients with advanced hepatocellular carcinoma.

    abstract：AIM:Tamibarotene is a synthetic retinoid expected to inhibit tumor-cell proliferation and to induce apoptosis by selective interaction with retinoic acid receptor α/β. We conducted an open-label phase I/II study to determine the maximum tolerated dose (MTD) and recommended dose (RD), and to evaluate the pharmacokinetic...

    journal_title：Hepatology international

    pub_type： 杂志文章

    doi：10.1007/s12072-013-9459-7

    authors： Kanai F,Obi S,Fujiyama S,Shiina S,Tamai H,Mochizuki H,Koike Y,Imamura J,Yamaguchi T,Saida I,Yokosuka O,Omata M

    更新日期：2014-01-01 00:00:00

  • Recurrence rates and factors for recurrence after radiofrequency ablation combined with transarterial chemoembolization for hepatocellular carcinoma: a retrospective cohort study.

    abstract：PURPOSE:There have been reports that radiofrequency ablation (RFA) combined with transarterial chemoembolization (TACE) is as equally effective as surgical resection for the treatment of hepatocellular carcinoma (HCC). This study aimed to evaluate recurrence rate and risk factor of recurrence after RFA combined with TA...

    journal_title：Hepatology international

    pub_type： 杂志文章

    doi：10.1007/s12072-011-9290-y

    authors： Kim JH,Yim HJ,Lee KG,Kim SY,Jung ES,Jung YK,Kim JH,Seo YS,Yeon JE,Lee HS,Um SH,Byun KS,Ryu HS

    更新日期：2012-04-01 00:00:00

  • Predictors of outcome in acute-on-chronic liver failure in children.

    abstract：BACKGROUND AND AIMS:Acute-on-chronic liver failure (ACLF) is associated with a high mortality rate in the absence of liver transplantation. There is limited data on predictors of survival in ACLF in children. Therefore, we prospectively studied the predictors of outcome of ACLF in children. METHODS:A prospective evalu...

    journal_title：Hepatology international

    pub_type： 杂志文章

    doi：10.1007/s12072-010-9217-z

    authors： Lal J,Thapa BR,Rawal P,Ratho RK,Singh K

    更新日期：2011-06-01 00:00:00

  • Survival advantage of primary liver transplantation for hepatocellular carcinoma within the up-to-7 criteria with microvascular invasion.

    abstract：PURPOSE:Microvascular invasion of hepatocellular carcinoma (HCC) is considered a poor prognostic factor of liver resection (LR) and liver transplantation (LT), but its significance for lesions within the up-to-7 criteria is unclear. This study investigated the survival benefit of primary LT against LR for HCC with micr...

    journal_title：Hepatology international

    pub_type： 杂志文章

    doi：10.1007/s12072-011-9318-3

    authors： Chan SC,Fan ST,Chok KS,Cheung TT,Chan AC,Fung JY,Poon RT,Lo CM

    更新日期：2011-10-21 00:00:00

  • A case-control study on sequence variations in the enhancer II/core promoter/precore and X genes of hepatitis B virus in patients with hepatocellular carcinoma.

    abstract：PURPOSE:To evaluate the sequence variations in the enhancer II (EnhII)/basal core promotor (BCP)/precore (PC) and X genes of hepatitis B virus (HBV) in Thai patients with hepatocellular carcinoma (HCC) by conducting a cross-sectional case-control study. METHODS:As much as 60 patients with HCC and 60 patients without H...

    journal_title：Hepatology international

    pub_type： 杂志文章

    doi：10.1007/s12072-010-9197-z

    authors： Tangkijvanich P,Sa-Nguanmoo P,Mahachai V,Theamboonlers A,Poovorawan Y

    更新日期：2010-07-31 00:00:00

  • An imbalance between stellate cells and γδT cells contributes to hepatocellular carcinoma aggressiveness and recurrence.

    abstract：PURPOSE:The diagnostic potential of hepatic stellate cells (HSCs) and γδT cells for patients with hepatocellular carcinoma (HCC) and their synergistic contributions to the prognosis of these patients have not yet been investigated. The aim of this study was to elucidate the prognostic value of these cells in HCC. METH...

    journal_title：Hepatology international

    pub_type： 杂志文章

    doi：10.1007/s12072-019-09969-w

    authors： Zhou BY,Gong JH,Cai XY,Wang JX,Luo F,Jiang N,Gong JP,Du CY,Liao R

    更新日期：2019-09-01 00:00:00

  • Impact of viral hepatitis B status on outcomes of intrahepatic cholangiocarcinoma: a meta-analysis.

    abstract：BACKGROUND AND AIMS:To estimate the impact of viral hepatitis B status on outcomes of intrahepatic cholangiocarcinoma. METHODS:We searched Pubmed and Embase for original articles that evaluated the impact of hepatitis B virus infection on outcomes of intrahepatic cholangiocarcinoma. The present study was conducted to ...

    journal_title：Hepatology international

    pub_type： 杂志文章,meta分析,评审

    doi：10.1007/s12072-018-9881-y

    authors： Jeong S,Luo G,Wang ZH,Sha M,Chen L,Xia Q

    更新日期：2018-07-01 00:00:00

  • Renal function and severity of bright liver. Relationship with insulin resistance, intrarenal resistive index, and glomerular filtration rate.

    abstract：AIMS:Relationships of renal function and liver disease are described in acute and chronic liver failure. The aim of the study is to investigate which relationship, if any, is present between severity of non-alcoholic fatty liver disease (NAFLD), assessed by bright liver score (BLS) versus mild-moderate renal insufficie...

    journal_title：Hepatology international

    pub_type： 杂志文章

    doi：10.1007/s12072-011-9254-2

    authors： Catalano D,Trovato GM,Martines GF,Pirri C,Trovato FM

    更新日期：2011-09-01 00:00:00

  • Acute kidney injury in hepatitis B-related acute-on-chronic liver failure without preexisting liver cirrhosis.

    abstract：BACKGROUND AND AIM:Acute kidney injury (AKI), as defined by the Acute Kidney Injury Network, has been widely investigated in decompensated liver cirrhosis patients. AKI is frequently progressive and independently associated with mortality in these patients. However, in the Asia-Pacific region, the majority of cases of ...

    journal_title：Hepatology international

    pub_type： 杂志文章

    doi：10.1007/s12072-015-9636-y

    authors： Huang Z,Lin C,Fang J,Wang N,Zhou R,Pan C

    更新日期：2015-07-01 00:00:00

  • Asian-Pacific clinical practice guidelines on the management of hepatitis B: a 2015 update.

    abstract：:Worldwide, some 240 million people have chronic hepatitis B virus (HBV), with the highest rates of infection in Africa and Asia. Our understanding of the natural history of HBV infection and the potential for therapy of the resultant disease is continuously improving. New data have become available since the previous ...

    journal_title：Hepatology international

    pub_type： 杂志文章,实务指引

    doi：10.1007/s12072-015-9675-4

    authors： Sarin SK,Kumar M,Lau GK,Abbas Z,Chan HL,Chen CJ,Chen DS,Chen HL,Chen PJ,Chien RN,Dokmeci AK,Gane E,Hou JL,Jafri W,Jia J,Kim JH,Lai CL,Lee HC,Lim SG,Liu CJ,Locarnini S,Al Mahtab M,Mohamed R,Omata M,Park J,

    更新日期：2016-01-01 00:00:00

  • Assessment of the features of serum apolipoprotein profiles in chronic HCV infection: difference between HCV genotypes 1b and 2.

    abstract：BACKGROUND:The life cycle of hepatitis C virus (HCV) is tightly associated with host lipoprotein metabolic pathways. Apolipoprotein is present on the outer surface of lipoprotein particles and plays an important role in lipoprotein metabolism. We aimed to elucidate the influence of chronic HCV infection on serum apolip...

    journal_title：Hepatology international

    pub_type： 杂志文章

    doi：10.1007/s12072-014-9572-2

    authors： Seki N,Sugita T,Aida Y,Itagaki M,Ishiguro H,Sutoh S,Abe H,Tsubota A,Matsushima M,Aizawa Y

    更新日期：2014-10-01 00:00:00

  • Reversal of NASH fibrosis with pharmacotherapy.

    abstract：:NAFLD is a spectrum of liver disease starting with fatty liver at one end of the spectrum and cirrhosis or liver cancer at the other end. Worldwide, NAFLD has become one of the most common liver diseases and it has also become one of the leading indications for liver transplantation. Our understanding of the NAFLD epi...

    journal_title：Hepatology international

    pub_type： 杂志文章,评审

    doi：10.1007/s12072-019-09970-3

    authors： Alukal JJ,Thuluvath PJ

    更新日期：2019-09-01 00:00:00

  • Significant decrease in Faecalibacterium among gut microbiota in nonalcoholic fatty liver disease: a large BMI- and sex-matched population study.

    abstract：BACKGROUND:Compositional changes of the gut microbiota are known to occur in patients with nonalcoholic fatty liver disease (NAFLD); however, the changes did not corroborate between the studies. We evaluated the gut microbiota between NAFLD and non-NAFLD participants, excluding the influence of obesity and sex in this ...

    journal_title：Hepatology international

    pub_type： 杂志文章

    doi：10.1007/s12072-019-09987-8

    authors： Iino C,Endo T,Mikami K,Hasegawa T,Kimura M,Sawada N,Nakaji S,Fukuda S

    更新日期：2019-11-01 00:00:00

  • Obstructive sleep apnea is an important predictor of hepatic fibrosis in patients with nonalcoholic fatty liver disease in a tertiary care center.

    abstract：BACKGROUND:The association of obstructive sleep apnea (OSA) with nonalcoholic fatty liver disease (NAFLD) has only been studied in selected subgroups such as the morbidly obese. We aimed to determine the prevalence and effect of OSA on NAFLD and vice versa in unselected patients attending the outpatient department. ME...

    journal_title：Hepatology international

    pub_type： 杂志文章

    doi：10.1007/s12072-015-9615-3

    authors： Agrawal S,Duseja A,Aggarwal A,Das A,Mehta M,Dhiman RK,Chawla Y

    更新日期：2015-04-01 00:00:00

  • Prednisolone plus S-adenosil-L-methionine in severe alcoholic hepatitis.

    abstract：PURPOSE/BACKGROUND:Severe alcoholic hepatitis (AH) is a life-threatening liver disease with a potential of 30-40 % mortality at 1 month. While steroids remain to be a first line therapy, they provide only about 50 % survival benefit. The aim of the study was to evaluate the efficacy of glucocorticoids plus S-adenosylme...

    journal_title：Hepatology international

    pub_type： 杂志文章,多中心研究

    doi：10.1007/s12072-016-9751-4

    authors： Tkachenko P,Maevskaya M,Pavlov A,Komkova I,Pavlov C,Ivashkin V

    更新日期：2016-11-01 00:00:00

  • A randomized trial of 24 versus 48 weeks of peginterferon α-2a in patients infected with chronic hepatitis C virus genotype 2 or low viral load genotype 1: a multicenter national study in Japan.

    abstract：:In a country such as Japan with the average age of patients with chronic hepatitis C treated with antivirals sometimes well above 60 years, the standard combination therapy is not well tolerated. In this randomized, prospective, controlled trial, we investigated the efficacy of 24-week peginterferon α monotherapy for ...

    journal_title：Hepatology international

    pub_type： 杂志文章

    doi：10.1007/s12072-009-9134-1

    authors： Iwasaki Y,Shiratori Y,Hige S,Nishiguchi S,Takagi H,Onji M,Yoshida H,Izumi N,Kohgo Y,Yamamoto K,Sato N,Shibuya A,Saito H,Sata M,Suzuki K,Kaneko S,Moriyama M,Omata M

    更新日期：2009-09-01 00:00:00

  • The utility of noninvasive scores in assessing the prevalence of nonalcoholic fatty liver disease and advanced fibrosis in type 1 diabetic patients.

    abstract：GOALS:The aim of our study is to assess the prevalence of nonalcoholic fatty liver disease (NAFLD) and advanced hepatic fibrosis in patients with type 1 diabetes (T1D) using simple noninvasive scores. BACKGROUND:There is paucity of data on the prevalence of NAFLD in T1D. Moreover, T1D could be a risk factor for advanc...

    journal_title：Hepatology international

    pub_type： 杂志文章

    doi：10.1007/s12072-017-9840-z

    authors： Singh A,Le P,Lopez R,Alkhouri N

    更新日期：2018-01-01 00:00:00

  • Incidence, risk factors, and prognosis of abnormal liver biochemical tests in COVID-19 patients: a systematic review and meta-analysis.

    abstract：BACKGROUND AND AIMS:Coronavirus disease 2019 (COVID-19) pandemic is ongoing. Except for lung injury, it is possible that COVID-19 patients develop liver injury. Thus, we conducted a systematic review and meta-analysis to explore the incidence, risk factors, and prognosis of abnormal liver biochemical tests in COVID-19 ...

    journal_title：Hepatology international

    pub_type： 杂志文章,meta分析

    doi：10.1007/s12072-020-10074-6

    authors： Wu Y,Li H,Guo X,Yoshida EM,Mendez-Sanchez N,Levi Sandri GB,Teschke R,Romeiro FG,Shukla A,Qi X

    更新日期：2020-09-01 00:00:00

  • Hepatic encephalopathy in acute-on-chronic liver failure.

    abstract：:The presence of hepatic encephalopathy (HE) within 4 weeks is part of the criteria for defining acute-on-chronic liver failure (ACLF). The pathophysiology of HE is complex, and hyperammonemia and cerebral hemodynamic dysfunction appear to be central in the pathogenesis of encephalopathy. Recent data also suggest that ...

    journal_title：Hepatology international

    pub_type： 杂志文章,评审

    doi：10.1007/s12072-015-9626-0

    authors： Lee GH

    更新日期：2015-10-01 00:00:00

  • Natural history of HCV infection.

    abstract：BACKGROUND:There is much controversy surrounding the natural history of hepatitis C virus (HCV) infection. AIMS:The aim of this review was to review the natural history of HCV infection. METHODS:Published English literature was searched via pubmed and then reviewed. RESULTS:Approximately, 75-85% of HCV-infected pers...

    journal_title：Hepatology international

    pub_type： 杂志文章

    doi：10.1007/s12072-012-9355-6

    authors： Sarin SK,Kumar M

    更新日期：2012-10-01 00:00:00

  • Spontaneous regression of a solitary necrotic nodule of the liver.

    abstract：:Solitary necrotic nodules of the liver occur rarely. Although these nodules are usually benign, they are surgically removed in most cases because they cannot be differentiated from malignant lesions. To date, the natural history of solitary fibrous nodules remains unclear. We present the case of an incidentally detect...

    journal_title：Hepatology international

    pub_type： 杂志文章

    doi：10.1007/s12072-010-9199-x

    authors： Choi CS,Cho EY,Jeong JS,Im CJ,Yang BJ,Kim HC

    更新日期：2010-07-29 00:00:00

  • Non-alcoholic hepatic steatosis attenuates hepatitis B virus replication in an HBV-immunocompetent mouse model.

    abstract：OBJECTIVE:The relationship between chronic hepatitis B virus (HBV) infection and fatty liver in patients remains unclear. Although high-fat diets-induced hepatic steatosis was proved to reduce HBV replication in transgenic mice, the interplay between HBV and fatty liver in immunocompetent mouse model is yet to be eluci...

    journal_title：Hepatology international

    pub_type： 杂志文章

    doi：10.1007/s12072-018-9877-7

    authors： Hu D,Wang H,Wang H,Wang Y,Wan X,Yan W,Luo X,Ning Q

    更新日期：2018-09-01 00:00:00

  • Hepatitis B virus reactivation in patients receiving cancer chemotherapy: natural history, pathogenesis, and management.

    abstract：:Chronic hepatitis B virus (HBV) infection is endemic in the Asian-Pacific region, and reactivation of HBV post-cancer chemotherapy has become an emerging clinical challenge. Patients with detectable serum HBV DNA before chemotherapy and those receiving intensive chemotherapy are particularly at a risk of HBV reactivat...

    journal_title：Hepatology international

    pub_type： 杂志文章

    doi：10.1007/s12072-011-9279-6

    authors： Liu CJ,Chen PJ,Chen DS,Kao JH

    更新日期：2013-06-01 00:00:00