Hepatitis B reactivation after chemotherapy: two decades of clinical research.

abstract：:In patients with chronic hepatitis B (CHB), liver fibrosis assessment is essential not only for determining prognosis but also for identifying patients who should receive treatment. Liver biopsy is limited by its invasiveness and sampling error. To explore effective non-invasive methods for liver fibrosis assessment, ...

journal_title：Hepatology international

authors： Chen YP,Peng J,Hou JL

更新日期：2013-06-01 00:00:00

abstract：:Drug-induced liver injury (DILI) is an important clinical problem, which has received more attention in recent decades. It can be induced by small chemical molecules, biological agents, traditional Chinese medicines (TCM), natural medicines (NM), health products (HP), and dietary supplements (DS). Idiosyncratic DILI i...

journal_title：Hepatology international

authors： Yu YC,Mao YM,Chen CW,Chen JJ,Chen J,Cong WM,Ding Y,Duan ZP,Fu QC,Guo XY,Hu P,Hu XQ,Jia JD,Lai RT,Li DL,Liu YX,Lu LG,Ma SW,Ma X,Nan YM,Ren H,Shen T,Wang H,Wang JY,Wang TL,Wang XJ,Wei L,Xie Q,Xie W,

更新日期：2017-05-01 00:00:00

abstract：PURPOSE:Either combination treatment or monotherapy using agents with a high genetic barrier are recommended for hepatitis B e antigen (HBeAg)-negative chronic hepatitis B (CHB). The aim of this study was to compare effect of naïve HBeAg-negative CHB patients with either de novo combination of lamivudine (LAM) and adef...

journal_title：Hepatology international

authors： Wang LC,Chen EQ,Cao J,Liu L,Zheng L,Li DJ,Xu L,Lei XZ,Liu C,Tang H

更新日期：2011-06-01 00:00:00

abstract：:An ultrasound (US) examination is a common noninvasive technique widely applied for diagnosis of a variety of diseases. Based on the rapid development of US equipment, many US images have been accumulated and are now available and ready for the preparation of a database for the development of computer-aided US diagnos...

journal_title：Hepatology international

authors： Nishida N,Yamakawa M,Shiina T,Kudo M

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:The aim of our study was to explore how C1QTNF1-AS1 regulated miR-221-3p/SOCS3 axis in human hepatocellular carcinoma (HCC). METHODS:Differentially expressed lncRNAs and genes were examined via RNA-seq. GO analysis and KEGG pathway enrichment analysis were carried out based on the function of dys-regulated ...

journal_title：Hepatology international

authors： Li H,Zhang B,Ding M,Lu S,Zhou H,Sun D,Wu G,Gan X

更新日期：2019-05-01 00:00:00

abstract：:In a country such as Japan with the average age of patients with chronic hepatitis C treated with antivirals sometimes well above 60 years, the standard combination therapy is not well tolerated. In this randomized, prospective, controlled trial, we investigated the efficacy of 24-week peginterferon α monotherapy for ...

journal_title：Hepatology international

authors： Iwasaki Y,Shiratori Y,Hige S,Nishiguchi S,Takagi H,Onji M,Yoshida H,Izumi N,Kohgo Y,Yamamoto K,Sato N,Shibuya A,Saito H,Sata M,Suzuki K,Kaneko S,Moriyama M,Omata M

更新日期：2009-09-01 00:00:00

abstract：PURPOSE:Transcriptional silencing of tumor suppressor genes associated with DNA hypermethylation has been known as a hallmark of human cancer. In this study, we revealed that a local anesthetic, procaine (PCA), possessed growth-inhibitory and demethylating effect on human hepatoma cells in vitro and in vivo. METHODS:T...

journal_title：Hepatology international

authors： Tada M,Imazeki F,Fukai K,Sakamoto A,Arai M,Mikata R,Tokuhisa T,Yokosuka O

更新日期：2007-09-01 00:00:00

abstract：PURPOSE:To assess the accuracy of a formula derived from 159 living liver donors to estimate the liver size of a normal subject: standard liver weight (g) = 218 + body weight (kg) × 12.3 + 51 (if male). Standard liver volume (SLV) is attained by a conversion factor of 1.19 mL/g. METHODS:The total liver volume (TLV) of...

journal_title：Hepatology international

authors： Chan SC,Lo CM,Chok KS,Sharr WW,Cheung TT,Tsang SH,Chan AC,Fan ST

更新日期：2011-03-26 00:00:00

abstract：PURPOSE:Lamivudine treatment of chronic hepatitis B (CHB) is associated with frequent resistance and loss of clinical benefit. We present outcomes of lamivudine-refractory Japanese patients treated with entecavir for 3 years. METHODS:Eighty-two patients refractory to lamivudine therapy received entecavir 0.5 or 1 mg d...

journal_title：Hepatology international

authors： Karino Y,Toyota J,Kumada H,Katano Y,Izumi N,Kobashi H,Sata M,Moriyama M,Imazeki F,Kage M,Ishikawa H,Masaki N,Seriu T,Omata M

更新日期：2010-02-06 00:00:00

abstract：BACKGROUND:Initial presentation of hepatocellular carcinoma (HCC) at an advanced stage in patients under a regular surveillance program is a devastating problem. AIMS:We assessed the prevalence and factors associated with this surveillance failure. METHODS:A total of 304 HCC patients who received regular surveillance...

journal_title：Hepatology international

authors： Sinn DH,Yi J,Choi MS,Choi D,Gwak GY,Paik YH,Lee JH,Koh KC,Paik SW,Yoo BC

更新日期：2013-10-01 00:00:00

abstract：:The Chinese Society of Hepatology developed the current guidelines for the Management of Ascites and Its Related Complications in Cirrhosis based on the published evidences and the panelists' consensus. The guidelines provided recommendations for the diagnosis and management of cirrhotic ascites emphasizing a step-wis...

journal_title：Hepatology international

authors： Chinese Society of Hepatology, Chinese Medical Association.,Xu X,Duan Z,Ding H,Li W,Jia J,Wei L,Linghu E,Zhuang H

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Cytokines have been reported to be involved in the cirrhosis and hepatic encephalopathy (HE). Many aspects on the correlation between minimal HE (MHE) and cytokine levels were still unclear. METHODS:Two hundred eighty-nine HBV-infected cirrhotic patients were grouped: non MHE (n = 156), MHE (n...

journal_title：Hepatology international

authors： Li W,Li N,Wang R,Li Q,Wu H

更新日期：2015-04-01 00:00:00

abstract：PURPOSE:Despite improvements in immunosuppressive therapy, acute cellular rejection (ACR) remains an important cause of graft loss in patients undergoing liver transplantation. Recently, associations between cytokine gene polymorphisms in recipients and the occurrence of ACR have been reported. However, most studies di...

journal_title：Hepatology international

authors： Kamei H,Masuda S,Nakamura T,Ishigami M,Fujimoto Y,Ogura Y,Oike F,Takada Y,Hamajima N

更新日期：2013-07-01 00:00:00

abstract：AIM:Tamibarotene is a synthetic retinoid expected to inhibit tumor-cell proliferation and to induce apoptosis by selective interaction with retinoic acid receptor α/β. We conducted an open-label phase I/II study to determine the maximum tolerated dose (MTD) and recommended dose (RD), and to evaluate the pharmacokinetic...

journal_title：Hepatology international

authors： Kanai F,Obi S,Fujiyama S,Shiina S,Tamai H,Mochizuki H,Koike Y,Imamura J,Yamaguchi T,Saida I,Yokosuka O,Omata M

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND AND AIM:There is an increased awareness of de novo hepatitis B virus (HBV) infection (DNH) in hepatitis B surface antigen (HBsAg)-negative recipients receiving hepatitis B core antibody (HBcAb)-positive liver organ. Whether hepatitis B surface antibody (HBsAb) has positive result on preventing the occurrence...

journal_title：Hepatology international

authors： Yang Y,Huang A,Zhao Y

更新日期：2020-03-01 00:00:00

abstract：:Portal hypertension develops as a result of increased intrahepatic vascular resistance often caused by chronic liver disease that leads to structural distortion by fibrosis, microvascular thrombosis, dysfunction of liver sinusoidal endothelial cells (LSECs), and hepatic stellate cell (HSC) activation. While the basic ...

journal_title：Hepatology international

authors： McConnell M,Iwakiri Y

更新日期：2018-02-01 00:00:00

abstract：:Primary sclerosing cholangitis (PSC) is a rare cholestatic liver disease, characterized by multiple strictures and dilatations of the intra- and extrahepatic bile ducts, leading to progressive liver fibrosis, in 10-15% cholangiocarcinoma, and ultimately end-stage liver disease. The pathogenesis is poorly understood, b...

journal_title：Hepatology international

authors： Prokopič M,Beuers U

更新日期：2020-12-30 00:00:00

abstract：BACKGROUND AND AIMS:Coagulopathic bleeding risk prediction is challenging in decompensated cirrhosis (DC) by conventional assays. Viscoelastic tests (VETs) are likely to be more useful for assessing coagulation status in these patients. We investigated whether the VET (Sonoclot) parameters with fibrinogen could predict...

journal_title：Hepatology international

authors： Bihari C,Patil A,Shasthry SM,Baweja S,Kumar G,Sarin SK

更新日期：2020-07-01 00:00:00

abstract：PURPOSE:Case reports and small case series have reported a high rate of complications associated with chest tube placement for hepatic hydrothorax. We describe the in-hospital and 3-month outcomes of patients who have had this procedure. METHODS:A retrospective medical record review was performed of all patients admit...

journal_title：Hepatology international

authors： Orman ES,Lok AS

更新日期：2009-12-01 00:00:00

abstract：:Immunomodulatory cell therapy as a complement to standard pharmacotherapy represents a novel approach to solid organ allograft acceptance. This methodology may allow for a reduced dose of immunosuppressive drug to be administered and thus attenuate the severe side effects associated with long-term immunosuppression su...

journal_title：Hepatology international

authors： Benseler V,Obermajer N,Johnson CL,Soeder Y,Dahlke MD,Popp FC

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Compositional changes of the gut microbiota are known to occur in patients with nonalcoholic fatty liver disease (NAFLD); however, the changes did not corroborate between the studies. We evaluated the gut microbiota between NAFLD and non-NAFLD participants, excluding the influence of obesity and sex in this ...

journal_title：Hepatology international

authors： Iino C,Endo T,Mikami K,Hasegawa T,Kimura M,Sawada N,Nakaji S,Fukuda S

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Hepatocellular carcinoma (HCC) is one of the most common malignant neoplasms worldwide. The p53 gene is frequently mutated in some histological subtypes of HCC. The role of p53 mutations and polymorphic variant of codon 72 in the prognosis of disease is still unclear. The p53 tumor suppressor gene Arg72Pro p...

journal_title：Hepatology international

authors： Jia S,Tang W,Luo Y

更新日期：2013-06-01 00:00:00

abstract：:Patients (85%) with hepatocellular adenoma (HCA) are women taking oral contraceptives. They can be divided into four subgroups according to their genotype/phenotype features. (1) Hepatocyte nuclear factor 1alpha (HNF1alpha) biallelic somatic mutations are observed in 35% of the HCA cases. It occurs in almost all cases...

journal_title：Hepatology international

authors： Bioulac-Sage P,Laumonier H,Laurent C,Zucman-Rossi J,Balabaud C

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND AND AIMS:The liver plays a key role in the storage, metabolism and homeostasis of fat-soluble vitamins. We investigated the relation of Vitamin(Vit)A/D/E serum levels with severity of liver disease and portal hypertension (PHT). METHODS:VitA/D/E serum levels were assessed in 234 patients with advanced chron...

journal_title：Hepatology international

authors： Simbrunner B,Semmler G,Stadlmann A,Scheiner B,Schwabl P,Paternostro R,Bucsics T,Bauer D,Eigenbauer E,Pinter M,Stättermayer AF,Quehenberger P,Marculescu R,Trauner M,Mandorfer M,Reiberger T

更新日期：2020-12-01 00:00:00

abstract：PURPOSE/BACKGROUND:Severe alcoholic hepatitis (AH) is a life-threatening liver disease with a potential of 30-40 % mortality at 1 month. While steroids remain to be a first line therapy, they provide only about 50 % survival benefit. The aim of the study was to evaluate the efficacy of glucocorticoids plus S-adenosylme...

journal_title：Hepatology international

authors： Tkachenko P,Maevskaya M,Pavlov A,Komkova I,Pavlov C,Ivashkin V

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Controversy exists on whether tenofovir disoproxil fumarate (TDF) is superior to entecavir (ETV) in lowering the risk of hepatocellular carcinoma (HCC) development. This meta-analysis was performed to clarify this issue with critical clinical and methodological considerations. METHODS:PubMed, EMBASE, and Co...

journal_title：Hepatology international

authors： Li M,Lv T,Wu S,Wei W,Wu X,Ou X,Ma H,Chow SC,Kong Y,You H,Jia J

更新日期：2020-01-01 00:00:00

abstract：AIMS:Relationships of renal function and liver disease are described in acute and chronic liver failure. The aim of the study is to investigate which relationship, if any, is present between severity of non-alcoholic fatty liver disease (NAFLD), assessed by bright liver score (BLS) versus mild-moderate renal insufficie...

journal_title：Hepatology international

authors： Catalano D,Trovato GM,Martines GF,Pirri C,Trovato FM

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Coronavirus disease 2019 (COVID-19) pandemic is ongoing. Except for lung injury, it is possible that COVID-19 patients develop liver injury. Thus, we conducted a systematic review and meta-analysis to explore the incidence, risk factors, and prognosis of abnormal liver biochemical tests in COVID-19 ...

journal_title：Hepatology international

authors： Wu Y,Li H,Guo X,Yoshida EM,Mendez-Sanchez N,Levi Sandri GB,Teschke R,Romeiro FG,Shukla A,Qi X

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Early prediction of lamivudine (LAM) response by individualized monitoring of serum HBV DNA like roadmap concept, and investigation of the outcome after LAM discontinuation in renal transplant recipients (RTRs) with chronic hepatitis B (CHB). METHODS:We conducted a study on 19 RTRs with HBV infection receiv...

journal_title：Hepatology international

authors： Hu TH,Tsai MC,Chen YT,Chien YS,Hung CH,Chen TC,Tseng PL,Chang KC,Yen YH

更新日期：2012-04-01 00:00:00

abstract：PURPOSE:To evaluate the recent topics of Ballloon-occluded retrograde trasnvenous obliteration(B-RTO). METHOD:We overviewed the recent scientific papers regarding B-RTO. RESULT:B-RTO is a treatment method for occluding varices retrogradely using a sclerosing agent under balloon occlusion of a major draining vein. It ...

journal_title：Hepatology international

authors： Hirota S,Kobayashi K,Kako Y,Takaki H,Yamakado K

更新日期：2018-02-01 00:00:00