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Graft loss and poor outcomes after living-donor liver transplantation owing to arterioportal shunts caused by liver needle biopsies.

Abstract：

BACKGROUND:Arterioportal shunts (APS) are well-known critical complications after liver transplantation (OLT). The aims of this study were to assess the frequency and causes of APS after OLT and to analyze APS patients with poor outcomes. PATIENTS:We evaluated 1415 OLT recipients retrospectively investigating APS cases. RESULTS:APS were detected in at least 9 patients (0.6%). All patients with APS had a history of posttransplant invasive procedures; percutaneous transhepatic cholangio drainage (n = 6) or needle biopsy (LNB; n = 3). Two patients with poor outcomes showed proximal APS caused by LNBs. The other 7 patients with distal APSs, showed stable conditions. Imaging findings in the 2 proximal APS patients revealed drastic changes in graft hemodynamics. Although they finally underwent re-OLT, their outcomes were poor, owing to fatal complications associated with advanced collaterals. CONCLUSION:We concluded that even careful LNBs can cause APS at unexpected points. Earlier, more aggressive treatments are required, especially for proximal APS patients.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Hori T,Ueda M,Oike F,Ogura Y,Ogawa K,Nguyen JH,Yonekawa Y,Takada Y,Egawa H,Yoshizawa A,Sibulesky L,Balci D,Chen F,Baine AM,Uemoto S

doi

10.1016/j.transproceed.2010.04.032

subject

Has Abstract

pub_date

2010-09-01 00:00:00

pages

2642-4

issue

7

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(10)00897-3

journal_volume

42

pub_type

杂志文章

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