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Treatment of complex airway lesions after lung transplantation with self-expandable nitinol stents: early experience.

Abstract：

:Airway complications (AC) are considered a serious cause of morbidity after lung transplantation (LT). Mechanical dilatation, laser vaporization, and silicone stent placement usually solve it. However, the use of self-expandable metallic stents (SENS) may be indicated in selected cases. Ten lung transplant recipients with AC were treated with SENS. Six patients underwent LT for cystic fibrosis, 2 for idiopathic pulmonary fibrosis, 1 for bronchiectasis, and 1 for emphysema. All patients received at least 1 treatment attempt with dilatation and silicone stent placement. The indications for SENS placement were the presence of a tortuous airway axis with stenosis and malacia of the right main bronchus in 5 patients; a long stenosis of the main and intermediate right bronchus involving the upper lobe orifice in 3 patients; or malacia that could not be stabilized with silicone stents in 3 cases. In 1 patient the procedure was bilateral. Functional improvement was immediate with a mean forced expiratory volume at 1 second (FEV(1)) gain of 35%. No stent dislocation was observed. Symptoms did not occur again in 5 patients with previous recurrent episodes of pneumonia. One stenosis, which was due to the ingrowth of granulation tissue occurred at 6 months after the procedure, was successfully treated with mechanical dilatation and laser vaporization. The deployment of SENS in a selected group of patients with AC after LT was easy, safe, and effective.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Anile M,Venuta F,Diso D,Liparulo V,Ricella C,De Giacomo T,Pugliese F,Rolla M,Quattrucci S,Pecoraro Y,Rendina EA,Coloni GF

doi

10.1016/j.transproceed.2010.03.092

subject

Has Abstract

pub_date

2010-05-01 00:00:00

pages

1279-80

issue

4

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(10)00380-5

journal_volume

42

pub_type

杂志文章

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