Abstract:
:ABO-incompatible (ABOi) kidney transplantation represents a viable tool to increase the donor pool for kidney transplantation, however, increased alloimmune response has been debated. The early outcomes of 25 low-risk ABOi kidney transplant recipients were compared with thoroughly matched 50 ABO-compatible (ABOc) ones. The matching process was based on gender and age of recipients and immunologic parameters, such as panel reactive antibodies, number of human leukocyte antigen mismatches, and transplantation era. Three-month protocol kidney graft biopsy Banff scores and 1-year clinical outcomes were compared. Apart from C4d positivity, no statistically significant differences were found regarding the Banff scores between the two groups. Similarly, microvascular inflammation and tubulointerstitial injury revealed no differences either. The eGFR at 3 months and 1 year was similar in both groups. In conclusion, blood group incompatibility yields no additional microvascular and tubulointerstitial graft injury if desensitization protocol was applied to low-risk kidney transplant recipients.
journal_name
Transplant Procjournal_title
Transplantation proceedingsauthors
Osickova K,Parikova A,Maluskova J,Fronek J,Viklicky Odoi
10.1016/j.transproceed.2018.02.063subject
Has Abstractpub_date
2018-06-01 00:00:00pages
1305-1309issue
5eissn
0041-1345issn
1873-2623pii
S0041-1345(18)30214-8journal_volume
50pub_type
杂志文章abstract::Immunoisolation strategies have the potential to impact the treatment of several diseases, such as hemophilia, Parkinson's and endocrine disorders, such as parathryroid disorders and diabetes. The hallmark of these disease states is the amelioration of the disease process by replacement of the deficient protein. Natur...
journal_title:Transplantation proceedings
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journal_title:Transplantation proceedings
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journal_title:Transplantation proceedings
pub_type: 杂志文章
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2009.11.018
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journal_title:Transplantation proceedings
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journal_title:Transplantation proceedings
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doi:10.1016/j.transproceed.2012.01.027
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journal_title:Transplantation proceedings
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doi:10.1016/j.transproceed.2006.01.019
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journal_title:Transplantation proceedings
pub_type: 杂志文章,评审
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更新日期:2015-07-01 00:00:00
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journal_title:Transplantation proceedings
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journal_title:Transplantation proceedings
pub_type: 杂志文章
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2006.05.024
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2016.01.026
更新日期:2016-05-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2012.05.045
更新日期:2012-07-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2004.12.307
更新日期:2005-03-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2010.04.058
更新日期:2010-09-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2009.11.026
更新日期:2010-01-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2011.12.013
更新日期:2012-01-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章,评审
doi:
更新日期:1996-10-01 00:00:00
abstract::Significant islet allograft prolongation was achieved by ICAM-1/LFA-1 blockade. ICAM-1 antisense oligonucleotide IP-3082 was effective in improving islet function as well as prolonging graft survival. ...
journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:
更新日期:1995-12-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章,多中心研究
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更新日期:2005-11-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章,多中心研究
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更新日期:2012-07-01 00:00:00
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journal_title:Transplantation proceedings
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2006.02.118
更新日期:2006-06-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2013.08.005
更新日期:2013-09-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2006.10.141
更新日期:2006-12-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2018.04.050
更新日期:2018-11-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2006.02.015
更新日期:2006-05-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2006.03.062
更新日期:2006-05-01 00:00:00
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journal_title:Transplantation proceedings
pub_type: 杂志文章
doi:10.1016/j.transproceed.2004.11.104
更新日期:2004-12-01 00:00:00