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Effect of anti-lymphocyte antibody induction therapy on renal allograft survival.

Abstract：

:Our two meta-analyses show that antilymphocyte antibody induction therapy extends allograft survival when compared to induction therapy with cyclosporine, azathioprine, and prednisone with the majority of the benefit seen during the first 2 years after transplant. The benefit of induction therapy with respect to allograft survival is particularly important among patients with pretransplant panel reactive antibodies greater than 20%. Although our understanding of the role of antilymphocyte antibody induction therapy continues to evolve, these two meta-analyses provide evidence for its use in clinical renal transplantation.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Szczech LA,Feldman HI

doi

10.1016/s0041-1345(99)00094-9

subject

Has Abstract

pub_date

1999-05-01 00:00:00

pages

9S-11S

issue

3B Suppl

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(99)00094-9

journal_volume

31

pub_type

杂志文章,评审

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