Post-operative sore throat: effect of lignocaine jelly and spray with endotracheal intubation.

Abstract:

:The effects of laryngeal lignocaine spray and/or lignocaine jelly as lubricants were studied on the incidence of sore throat, hoarseness, or tracheal irritability as evidenced by either a tendency to cough or frank coughing after intubation with a Sensiv tube (Searle Medical Products). Pressure in the medium-volume, low-pressure cuff was controlled and kept below 2.5 kPa (25 cmH2O) during anaesthesia. The side-effects of 94 surgical patients were recorded in a double-blind manner in the recovery room and on the first post-operative day. The lowest number of patients (62%) with side-effects was found in the control group and the greatest (95%) after the combination of lignocaine jelly and spray (P less than 0.05). The number of side-effects after lignocaine jelly alone was 85% and after the spray alone 68%. Women were more prone to have side-effects, especially sore throat and hoarseness, than men (P less than 0.05). Induced hypotension did not increase the incidence of side-effects. Endotracheal cuff pressures were also studied in 114 patients during N2O-O2 anaesthesia and in 54 patients after the replacement of N2O with nitrogen. The minimum occluding pressure required was 1 kPa (10 cmH2O). In 42% of the patients receiving N2O a limiting value of 2.5 kPa (25 cmH2O) was reached during anesthesia in a mean time of 74 min (range 25-180 min). After the replacement of N2O with nitrogen, the cuff pressure decreased from 1.8 kPa (18 cmH2O) to 0.7 kPa (7 cmH2O) over 40 min. It is concluded that lignocaine jelly with the use of a spray significantly increases post-operative side-effects.

journal_name

Eur J Anaesthesiol

authors

Klemola UM,Saarnivaara L,Yrjölä H

subject

Has Abstract

pub_date

1988-11-01 00:00:00

pages

391-9

issue

6

eissn

0265-0215

issn

1365-2346

journal_volume

5

pub_type

临床试验,杂志文章,随机对照试验
  • Elimination of alfentanil delivered by infusion is not altered by the chronic administration of atorvastatin.

    abstract:BACKGROUND AND OBJECTIVE:Statins are prescribed for patients with hypercholesterolemia. Atorvastatin is metabolized by cytochrome P4503A4 and inhibits P4503A4 activity in vitro. Alfentanil is a potent opioid used in clinical anaesthetic practice and is also metabolized by P4503A4. This study tested the hypothesis that ...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章

    doi:10.1017/s0265021503001078

    authors: McDonnell CG,Malkan D,Van Pelt FD,Shorten GD

    更新日期:2003-08-01 00:00:00

  • Ultrasonographic finding of lung sliding in patients on mechanical ventilation with alveolar-interstitial syndrome.

    abstract:BACKGROUND AND OBJECTIVES:To determine the visibility of pleural lung sliding in alveolar-interstitial syndrome (AIS) in patients on mechanical ventilation at two different time points, as a confirmatory ultrasonographic method for excluding pneumothorax. METHODS:Fifty-two mechanically ventilated patients in the semir...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0b013e32833feb40

    authors: Rode B,Vučić M,Siranović M,Kovač N,Kelečić M,Gopčević A

    更新日期:2011-04-01 00:00:00

  • Effects of isovolaemic haemodilution on oxygenation of liver and skeletal muscle.

    abstract:BACKGROUND AND OBJECTIVE:Hydroxyethyl starch is frequently used for volume substitution during surgical procedures and for isovolaemic haemodilution. Haemodilution has also been shown to improve tissue oxygen tension in skeletal muscle: However, effects of this volume substitute on tissue oxygen tension of the liver du...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1017/s0265021505000323

    authors: Gottschalk A,Standl TG,Freitag M,Radtke P,Rempf C,Burmeister MA,Horn EP,Strate T,Schulte am Esch J

    更新日期:2005-03-01 00:00:00

  • Five oxygen-nitrous oxide proportioning systems compared.

    abstract::The majority of contemporary gas delivery modules, on anaesthetic workstations, are equipped with oxygen-nitrous oxide proportioning systems which should prevent the delivery of hypoxic gas mixtures. We investigated five modules, of two different types, using fresh gas flows ranging from 50 mL min-1 to 20 L min-1 with...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/00003643-199601000-00013

    authors: Feigenwinter P,Pohle TH,Zbinden AM

    更新日期:1996-01-01 00:00:00

  • Advanced trauma life support.

    abstract::From a family tragedy 20 years ago, ATLS has truly become an international trauma care program. Its success is demonstrated not only in the large number of physicians that have been trained, but also in the appearance of a number of affiliated courses with a similar structure, aimed at training medical, nursing, civil...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,评审

    doi:10.1046/j.1365-2346.1996.00939.x

    authors: Gwinnutt CL,Driscoll PA

    更新日期:1996-03-01 00:00:00

  • Onset time of topical analgesia with EMLA 5%: no reduction with glyceryl trinitrate.

    abstract::Many adults are distressed by painful investigations or treatment, including venepuncture. The early effects of Eutectic Mixture of Local Anaesthetics (EMLA) 5%, on relief of pinprick pain in the antecubital area was investigated and compared with EMLA plus glyceryl trinitrate and with a placebo cream in 100 patients....

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00003643-199601000-00004

    authors: Nott MR,Clemson CJ,Peacock JL

    更新日期:1996-01-01 00:00:00

  • Implementation of patient blood management remains extremely variable in Europe and Canada: the NATA benchmark project: An observational study.

    abstract:BACKGROUND:Preoperative anaemia is associated with increased postoperative morbidity and mortality. Patient blood management (PBM) is advocated to improve patient outcomes. OBJECTIVES:NATA, the 'Network for the advancement of patient blood management, haemostasis and thrombosis', initiated a benchmark project with the...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,多中心研究

    doi:10.1097/EJA.0000000000000519

    authors: Van der Linden P,Hardy JF

    更新日期:2016-12-01 00:00:00

  • Combination of low doses of intrathecal ketamine and midazolam with bupivacaine improves postoperative analgesia in orthopaedic surgery.

    abstract:BACKGROUND:Intrathecal ketamine produces a short period of analgesia with stable haemodynamics. Midazolam with bupivacaine prolongs the duration of analgesia when administered intrathecally but does not prevent hypotension. The objective of this study was to assess the effect of a combination of intrathecal bupivacaine...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1017/S0265021507002645

    authors: Murali Krishna T,Panda NB,Batra YK,Rajeev S

    更新日期:2008-04-01 00:00:00

  • Therapeutic approaches for the prevention of secondary brain injury.

    abstract::The precise mechanisms underlying secondary brain damage after traumatic injury to the central nervous system (CNS) are not well understood, and delayed neuronal injury may result from pathological changes in neurotransmitter release, synthesis or generation of endogenous autodestructive neurochemicals and/ or inflamm...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,评审

    doi:10.1046/j.1365-2346.1996.00981.x

    authors: McIntosh TK,Smith DH,Garde E

    更新日期:1996-05-01 00:00:00

  • Platelet function recovery after cessation of aspirin: preliminary study of volunteers and surgical patients.

    abstract:BACKGROUND AND OBJECTIVE:Recent evidence indicates that platelet function may recover more rapidly after cessation of aspirin therapy than previously thought. The present study evaluated the effect of aspirin on platelet function using platelet aggregometry in healthy individuals and in aspirin-treated patients schedul...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0b013e328335b354

    authors: Zisman E,Erport A,Kohanovsky E,Ballagulah M,Cassel A,Quitt M,Pizov R

    更新日期:2010-07-01 00:00:00

  • Fentanyl pre-treatment does not affect the pharmacokinetic profile of an induction dose of propofol in adults.

    abstract::The initial disposition of propofol was reported to change when the administration was preceded by fentanyl. The pharmacokinetic profile of the induction dose of propofol (2 mg kg-1 body weight) was studied in 20 ASA I patients randomly allocated to receive fentanyl 1.5 microgram kg-1 (n = 12) or not (n = 8). Anaesthe...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: De Gasperi A,Cristalli A,Noé L,Sabbadini D,Mazza E,Prosperi M,Fantini G,Crespi AM,Rezzani S

    更新日期:1994-03-01 00:00:00

  • Perioperative assessment of coagulation in paediatric neurosurgical patients using thromboelastography.

    abstract:BACKGROUND AND OBJECTIVE:Primary brain tumours may be associated with coagulation disorders, which can pose intraoperative and postoperative management difficulties. Thromboelastography is a useful technique for evaluating coagulability. In this study, we evaluated the perioperative coagulation profile using both stand...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0b013e32831c8b5f

    authors: El Kady N,Khedr H,Yosry M,El Mekawi S

    更新日期:2009-04-01 00:00:00

  • The relative potencies of thiopentone and propofol.

    abstract::The relative potencies of the intravenous anaesthetics propofol and thiopentone have been investigated by finding the dose necessary to produce unconsciousness in approximately 30%, 50% and 80% of patients. The estimated potency of propofol to thiopentone was 1:1.604 as obtained by the probit method of analysis which ...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Grounds RM,Moore M,Morgan M

    更新日期:1986-01-01 00:00:00

  • CobraPLUS and Cookgas air-Q versus Fastrach for blind endotracheal intubation: a randomised controlled trial.

    abstract:BACKGROUND AND OBJECTIVE:CobraPLUS and Cookgas air-Q are supraglottic airways expected to allow safe ventilation as well as reliable blind intubation. In a prospective, controlled trial, we hypothesised that quality of ventilation and success rate of blind endotracheal intubation of these new devices would be superior ...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/EJA.0b013e328340c352

    authors: Erlacher W,Tiefenbrunner H,Kästenbauer T,Schwarz S,Fitzgerald RD

    更新日期:2011-03-01 00:00:00

  • Development and performance testing of the low-cost, 3D-printed, smartphone-compatible 'Tansen Videolaryngoscope' vs. Pentax-AWS videolaryngoscope vs. direct Macintosh laryngoscope: A manikin study.

    abstract:BACKGROUND:While videolaryngoscopes help in the management of difficult airways, they remain too expensive for those with limited resources. We have developed a robust, re-usable, low-cost videolaryngoscope at United Mission Hospital Tansen, Nepal, by combining a smartphone-compatible endoscope capable of capturing sti...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0000000000001264

    authors: Lambert CT,John SC,John AV

    更新日期:2020-11-01 00:00:00

  • Impact of disruptions on anaesthetic workflow during anaesthesia induction and patient positioning: A prospective study.

    abstract:BACKGROUND:Work disruption in operating rooms hinders flow of patients and increases chances of error. Previous studies have largely considered the types of disruption occurring in operating rooms, but have not analysed systematically the objective impact of disruption. OBJECTIVE:The objective was to evaluate the impa...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,多中心研究

    doi:10.1097/EJA.0000000000000484

    authors: Al-Hakim L,Arora S,Sevdalis N

    更新日期:2016-08-01 00:00:00

  • The use of ultrasound to guide time-critical cannula tracheotomy when anterior neck airway anatomy is unidentifiable.

    abstract:BACKGROUND AND OBJECTIVE:Transtracheal or transcricothyroid placement of a cannula is a practice used in a number of aspects of airway management in anaesthesia and intensive care. In this study, we aimed to investigate whether the use of ultrasound will facilitate cannula placement in a time-critical situation in pati...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/EJA.0b013e328344b4e1

    authors: Dinsmore J,Heard AM,Green RJ

    更新日期:2011-07-01 00:00:00

  • The ProSeal laryngeal mask airway and the laryngeal tube Suction for ventilation in gynaecological patients undergoing laparoscopic surgery.

    abstract:BACKGROUND AND OBJECTIVE:ProSeal Laryngeal Mask Airway (PLMA) and Laryngeal Tube Suction (LTS), supraglottic airway devices allowing gastric drainage, were compared in this prospective, randomized study for airway management under conditions with elevated intra-abdominal pressure induced by capnoperitoneum. METHODS:Fi...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1017/s0265021505000220

    authors: Roth H,Genzwuerker HV,Rothhaas A,Finteis T,Schmeck J

    更新日期:2005-02-01 00:00:00

  • Relationship of the internal jugular vein to the common carotid artery: implications for ultrasound-guided vascular access.

    abstract:BACKGROUND AND OBJECTIVE:For cannulation of the internal jugular vein (IJV), ultrasound increases the number of first pass successes and reduces the rate of mechanical complications. A frequent complication of IJV access is the accidental injury of the common carotid artery (CCA), which can be dangerous in some circums...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0b013e328341a492

    authors: Maecken T,Marcon C,Bomas S,Zenz M,Grau T

    更新日期:2011-05-01 00:00:00

  • Duration of stabilization of control responses affects the onset and duration of action of rocuronium but not suxamethonium.

    abstract::The effect of the duration of stabilization of control responses on the onset and duration of clinical relaxation of suxamethonium 1 mg kg-1 and rocuronium 0.6 mg kg-1 were investigated in 90 patients. The control responses were allowed to stabilize for 1, 5, 10, 15 or 20 min prior to administration of rocuronium and ...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1365-2346.1996.d01-379.x

    authors: Symington MJ,McCoy EP,Mirakhur RK,Kumar N

    更新日期:1996-07-01 00:00:00

  • Perioperative care of diabetic patients.

    abstract::Diabetes mellitus is the most common metabolic disease and its incidence is increasing. New classifications have been recently proposed based upon a better knowledge of pathogenesis, mechanisms of glucose transport and insulin resistance. The perioperative care of diabetic patients is less dependent on blood-glucose c...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,评审

    doi:10.1046/j.0265-0215.2001.00876.x

    authors: Scherpereel PA,Tavernier B

    更新日期:2001-05-01 00:00:00

  • Intra-operative norepinephrine administration and cancer-related outcomes following radical cystectomy for bladder cancer: A cohort study.

    abstract:BACKGROUND:The impact of anaesthetic techniques on recurrence of cancers is controversial. Elevated plasma catecholamine levels have been implicated in angiogenesis and metastasis in various cancers. OBJECTIVES:To assess the potential association between continuous intra-operative norepinephrine administration and tum...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0000000000001155

    authors: Löffel LM,Furrer MA,Favre A,Engel D,Gahl B,Burkhard FC,Wuethrich PY

    更新日期:2020-05-01 00:00:00

  • Effect of pre-operative oral carbohydrate loading on recovery after day-case cholecystectomy: A randomised controlled trial.

    abstract:BACKGROUND:Pre-operative carbohydrate loading has been shown to reduce pre-operative discomfort and postoperative nausea and vomiting in general surgical patients. Few studies have considered day-case surgery. OBJECTIVE:The aim of this prospective randomised study was to determine whether pre-operative carbohydrate lo...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/EJA.0000000000001002

    authors: Helminen H,Branders H,Ohtonen P,Saarnio J

    更新日期:2019-08-01 00:00:00

  • A prospective evaluation of the failure rate of spinal anaesthesia for transurethral prostatic resection.

    abstract::The rate of failed spinal anaesthesia, defined as the need for unplanned general anaesthesia, was evaluated in a prospective study involving 137 patients undergoing transurethral resection of the prostate (TURP). The incidence of sensations at the operative site which did not require general anaesthesia was also evalu...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Guinard JP,Carpenter RL,Smith HS

    更新日期:1992-01-01 00:00:00

  • Effects of pneumoperitoneum and reverse Trendelenburg position on cardiopulmonary function in morbidly obese patients receiving laparoscopic gastric banding.

    abstract::We prospectively evaluated the effects of pneumoperitoneum and reverse Trendelenburg position on cardiopulmonary function in 20 ASA physical status II-III morbidly obese patients (body mass index > 35 kg m(-2)) undergoing laparoscopic gastric banding. After general anaesthesia was induced, patients' lungs were ventila...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章

    doi:10.1046/j.1365-2346.2000.00662.x

    authors: Casati A,Comotti L,Tommasino C,Leggieri C,Bignami E,Tarantino F,Torri G

    更新日期:2000-05-01 00:00:00

  • The effects of sevoflurane, isoflurane and desflurane on QT interval of the ECG.

    abstract:BACKGROUND AND OBJECTIVE:To determine if there is any significant difference between the effects of desflurane, isoflurane and sevoflurane on the QT interval, QT dispersion, heart rate corrected QT interval and QTc dispersion of the electrocardiogram. METHODS:The study was conducted in a prospective, double blind and ...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1017/s0265021504007112

    authors: Yildirim H,Adanir T,Atay A,Katircioğlu K,Savaci S

    更新日期:2004-07-01 00:00:00

  • Stressors in anaesthesiology: development and validation of a new questionnaire: A cross-sectional study of Portuguese anaesthesiologists.

    abstract:BACKGROUND:Stress in anaesthesiologists is a common and multifactorial problem related to patients, colleagues and organisations. The consequences of stress include depression, work-home conflicts and burnout. Reduction in stress can be achieved by reducing the number and magnitude of stressors or by increasing resilie...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0000000000000518

    authors: Lapa TA,Carvalho SA,Viana JS,Ferreira PL,Pinto-Gouveia J

    更新日期:2016-11-01 00:00:00

  • Comparison of a continuous noninvasive arterial pressure device with invasive measurements in cardiovascular postsurgical intensive care patients: a prospective observational study.

    abstract:BACKGROUND:Arterial pressure monitoring using the a continuous noninvasive arterial pressure (CNAP) device during general anaesthesia is known to be interchangeable with continuous invasive arterial pressure (CIAP) monitoring. Agreement with invasive measurements in cardiovascular postsurgical intensive care patients h...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章

    doi:10.1097/EJA.0000000000000136

    authors: Ilies C,Grudev G,Hedderich J,Renner J,Steinfath M,Bein B,Haake N,Hanss R

    更新日期:2015-01-01 00:00:00

  • Maintenance of surgical muscle relaxation by repeat doses of vecuronium and atracurium at three different dose levels.

    abstract::The time-course of the neuromuscular effects of vecuronium (n = 25) and atracurium (n = 25) has been compared at three different levels of maintenance dose in anaesthetized patients. Following intubation with vecuronium 0.1 mg kg-1 or atracurium 0.5 mg kg-1, surgical muscle relaxation was maintained by using increment...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章

    doi:

    authors: Khuenl-Brady KS,Scharz S,Richardson FJ,Mitterschiffthaler G

    更新日期:1991-01-01 00:00:00

  • Comparing peri-operative complications of paediatric and adult anaesthesia: A retrospective cohort study of 81 267 cases.

    abstract:BACKGROUND:Comparisons of peri-operative complications associated with paediatric (≤16 years) and adult anaesthesia are poorly available, especially in which cardiac surgery, organ transplantation and neurosurgery are involved. OBJECTIVE:The aim of this study was to evaluate the nature and incidence of peri-operative ...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0000000000000769

    authors: Westerkamp AC,de Geus AF,Molenbuur B,Meyer P,Wietasch JKG,Struys MMRF,Hendriks HGD

    更新日期:2018-04-01 00:00:00