Implementation of patient blood management remains extremely variable in Europe and Canada: the NATA benchmark project: An observational study.

Abstract:

BACKGROUND:Preoperative anaemia is associated with increased postoperative morbidity and mortality. Patient blood management (PBM) is advocated to improve patient outcomes. OBJECTIVES:NATA, the 'Network for the advancement of patient blood management, haemostasis and thrombosis', initiated a benchmark project with the aim of providing the basis for educational strategies to implement optimal PBM in participating centres. DESIGN:Prospective, observational study with online data collection in 11 secondary and tertiary care institutions interested in developing PBM. SETTING:Ten European centres (Austria, Spain, England, Denmark, Belgium, Netherlands, Romania, Greece, France, and Germany) and one Canadian centre participated between January 2010 and June 2011. PATIENTS:A total of 2470 patients undergoing total hip (THR) or knee replacement, or coronary artery bypass grafting (CABG), were registered in the study. Data from 2431 records were included in the final analysis. MAIN OUTCOME MEASURES:Primary outcome measures were the incidence and volume of red blood cells (RBC) transfused. Logistic regression analysis identified variables independently associated with RBC transfusions. RESULTS:The incidence of transfusion was significantly different between centres for THR (range 7 to 95%), total knee replacement (range 3 to 100%) and CABG (range 20 to 95%). The volume of RBC transfused was significantly different between centres for THR and CABG. The incidence of preoperative anaemia ranged between 3 and 40% and its treatment between 0 and 40%, the latter not being related to the former. Patient characteristics, evolution of haemoglobin concentrations and blood losses were also different between centres. Variables independently associated with RBC transfusion were preoperative haemoglobin concentration, lost volume of RBC and female sex. CONCLUSION:Implementation of PBM remains extremely variable across centres. The relative importance of factors explaining RBC transfusion differs across institutions, some being patient related whereas others are related to the healthcare process. The results reported confidentially to each centre will allow them to implement tailored measures to improve their PBM strategies.

journal_name

Eur J Anaesthesiol

authors

Van der Linden P,Hardy JF

doi

10.1097/EJA.0000000000000519

subject

Has Abstract

pub_date

2016-12-01 00:00:00

pages

913-921

issue

12

eissn

0265-0215

issn

1365-2346

journal_volume

33

pub_type

杂志文章,多中心研究
  • The effect of labetalol on urinary prostacyclin secretion during surgery.

    abstract::The effects of labetalol on the secretion of prostacyclin and plasma-renin activity (PRA) were evaluated, relative to a control group in 24 patients undergoing hip osteotomy. They were randomly assigned to two groups (G-I and G-II) with 12 patients each. Patients allocated to both groups received standard anaesthesia ...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Arroyo JL,Iribarren MJ,Dawson E,Roux C,Carrascosa F,De Castro J,Carrasco MS

    更新日期:1986-01-01 00:00:00

  • Cardiovascular responses and airway complications following awake nasal intubation with blind intubation device and fibreoptic bronchoscope: a randomized controlled study.

    abstract:BACKGROUND AND OBJECTIVE:The blind intubation device (BID) was introduced for awake nasotracheal intubation recently. The aim of this study was to compare the cardiovascular responses and associated airway complications of fibreoptic bronchoscope (FOB) with those of BID. The intubation attempts and intubation time were...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/EJA.0b013e328332845a

    authors: Sun Y,Liu JX,Jiang H,Zhu YS,Xu H,Huang Y

    更新日期:2010-05-01 00:00:00

  • Dolasetron for the prevention of postoperative nausea and vomiting following outpatient surgery with general anaesthesia: a randomized, placebo-controlled study. The Dolasetron PONV Prevention Study Group.

    abstract::In a multicentre, randomized, double-blind, placebo-controlled dose-ranging study, 1030 patients undergoing outpatient surgery with general anaesthesia received i.v. dolasetron mesylate (12.5, 25, 50, or 100 mg) or placebo. The principal outcome measure was the proportion of patients who were free of emesis or rescue ...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1046/j.1365-2346.2000.00594.x

    authors: Philip BK,Pearman MH,Kovac AL,Chelly JE,Wetchler BV,McKenzie R,Monk TG,Dershwitz M,Mingus M,Sung YF,Hahne WF,Brown RA

    更新日期:2000-01-01 00:00:00

  • Intrathecal hydromorphone added to hyperbaric bupivacaine for postoperative pain relief after knee arthroscopic surgery: a prospective, randomised, controlled trial.

    abstract:BACKGROUND AND OBJECTIVE:Adding opioid to spinal anaesthetic provides additional analgesia during the postoperative period. The purpose of this study was to determine the dose of intrathecal hydromorphone necessary to achieve postoperative pain relief after arthroscopic knee surgery. METHODS:In a prospective, double-b...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/EJA.0b013e3283476055

    authors: Lee YS,Park YC,Kim JH,Kim WY,Yoon SZ,Moon MG,Min TJ

    更新日期:2012-01-01 00:00:00

  • Use of EEG spectral edge as index of equipotency in a comparison of propofol and isoflurane for maintenance of general anaesthesia.

    abstract::Propofol and isoflurane were compared for haemodynamic stability and recovery time as main anaesthetic agents for maintenance in a total of 43 ASA I and II patients in uncomplicated operations lasting at least 30 min. The premedication (oral diazepam), induction (thiopentone-fentanyl-suxamethonium) and maintenance pro...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Gurman GM,Fajer S,Porat A,Schily M,Pearlman A

    更新日期:1994-11-01 00:00:00

  • Long-term outcome of patients who require renal replacement therapy after cardiac surgery.

    abstract:BACKGROUND AND OBJECTIVE:Acute renal failure is a serious complication of cardiac surgery. We studied the long-term survival and quality of life of patients requiring renal replacement therapy after cardiac surgery, since they represent a heavy burden on hospital resources and their outcome has never been adequately ev...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章

    doi:10.1017/S0265021505001705

    authors: Landoni G,Zangrillo A,Franco A,Aletti G,Roberti A,Calabrò MG,Slaviero G,Bignami E,Marino G

    更新日期:2006-01-01 00:00:00

  • Total hip arthroplasty and perioperative oral carbohydrate treatment: a randomised, double-blind, controlled trial.

    abstract:CONTEXT:Perioperative oral carbohydrate intake is beneficial to general surgery patients. Total hip arthroplasty is a common surgical procedure, and even a moderate improvement in patient outcome could have a significant effect on the resources needed for these patients. However, few studies have focused on the effects...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/EJA.0b013e3283525ba9

    authors: Harsten A,Hjartarson H,Toksvig-Larsen S

    更新日期:2012-06-01 00:00:00

  • The effect of dexmedetomidine sedation on brachial plexus block in patients with end-stage renal disease.

    abstract:BACKGROUND AND OBJECTIVE:The study investigated the effect of intravenous dexmedetomidine on brachial plexus block in patients with end-stage renal disease sedated with dexmedetomidine or midazolam for the formation of arteriovenous fistula. METHODS:A supraclavicular brachial plexus block was performed in 68 patients ...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/EJA.0b013e32832a2244

    authors: Rutkowska K,Knapik P,Misiolek H

    更新日期:2009-10-01 00:00:00

  • Isoflurane may not influence postoperative cardiac troponin I release and clinical outcome in adult cardiac surgery.

    abstract:BACKGROUND AND OBJECTIVE:Isoflurane has been shown experimentally to protect the myocardium against infarction but the clinical relevance of these findings is not yet well established. We therefore evaluated the effects of isoflurane administration before cardiopulmonary bypass (CPB) on postoperative cardiac troponin I...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1017/s0265021504009044

    authors: Fellahi JL,Gue X,Philippe E,Riou B,Gerard JL

    更新日期:2004-09-01 00:00:00

  • Propofol inhibits potassium chloride induced contractions of isolated human umbilical vessels.

    abstract:BACKGROUND AND OBJECTIVE:We have evaluated the effects of propofol and its relationship with K+ channels on human isolated umbilical vessels. METHODS:Umbilical vessel rings were suspended in isolated organ baths containing Krebs-Ringer solution. In the first series of experiments the effect of propofol (10(-9)-10(-4) ...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1017/S0265021505001924

    authors: Caliskan E,Kayhan Z,Tufan H

    更新日期:2006-05-01 00:00:00

  • Warming before and after epidural block before general anaesthesia for major abdominal surgery prevents perioperative hypothermia: A randomised controlled trial.

    abstract:BACKGROUND:Epidural analgesia (EDA) is known to be an independent risk factor for perioperative hypothermia and its many known adverse effects. Combined general and epidural anaesthesia decreases intraoperative core temperature more rapidly than general anaesthesia alone. Hence, adequate warming procedures are needed f...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/EJA.0000000000000369

    authors: Horn EP,Bein B,Broch O,Iden T,Böhm R,Latz SK,Höcker J

    更新日期:2016-05-01 00:00:00

  • Systemic and alveolar inflammatory response in the dependent and nondependent lung in patients undergoing lung resection surgery: A prospective observational study.

    abstract:BACKGROUND:Measurement of inflammatory mediators in bronchoalveolar lavage (BAL) during lung resection surgery with periods of one-lung ventilation (OLV) has revealed an intense local pulmonary response. The role of each lung in the inflammation that occurs during this procedure has never been investigated. OBJECTIVE(...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0000000000000233

    authors: de la Gala F,Piñeiro P,Garutti I,Reyes A,Olmedilla L,Cruz P,Duque P,Casanova J,Rancan L,Benito P,Vara E

    更新日期:2015-12-01 00:00:00

  • Reducing the incidence of sore throat with the laryngeal mask airway.

    abstract::The incidence of sore throat after the use of the laryngeal mask was assessed with a randomized trial in 839 patients. Sore throat occurred more often in women, older patients or after multiple insertion attempts. It was found that the frequency in women, but not in men, was lowered from 11.9% to 3.9% (P = 0.012) by r...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Nott MR,Noble PD,Parmar M

    更新日期:1998-03-01 00:00:00

  • Predictors of successful neuraxial block: a prospective study.

    abstract:BACKGROUND AND OBJECTIVE:The epidural and subarachnoid spaces should be identified at the first attempt, since multiple punctures increase the risk of postdural puncture headache, epidural haematoma and neural trauma. The study aimed to describe the predictors of successful neuraxial blocks at the first attempt. METHO...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章

    doi:10.1017/s0265021502000716

    authors: de Filho GR,Gomes HP,da Fonseca MH,Hoffman JC,Pederneiras SG,Garcia JH

    更新日期:2002-06-01 00:00:00

  • Prevention of atelectasis by continuous positive airway pressure in anaesthetised children: A randomised controlled study.

    abstract:BACKGROUND:Continuous positive airway pressure (CPAP) prevents peri-operative atelectasis in adults, but its effect in children has not been quantified. OBJECTIVE:The aim of this study was to evaluate the role of CPAP in preventing postinduction and postoperative atelectasis in children under general anaesthesia. DES...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0000000000001351

    authors: Acosta CM,Lopez Vargas MP,Oropel F,Valente L,Ricci L,Natal M,Suarez Sipmann F,Tusman G

    更新日期:2021-01-01 00:00:00

  • Effect of injection speed on anaesthetic spread during axillary block using the orthogonal two-needle technique.

    abstract::One hundred patients undergoing scheduled upper limb orthopaedic surgery were studied to determine if the speed of injection of the local anaesthetic solution could modify the extent and depth of anaesthesia with the axillary approach to the brachial plexus. The blocks were performed using the 'orthogonal two-needle t...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Rucci FS,Pippa P,Boccaccini A,Barbagli R

    更新日期:1995-09-01 00:00:00

  • McGRATH MAC video laryngoscope for insertion of a transoesophageal echocardiography probe: A randomised controlled trial.

    abstract:BACKGROUND:Transoesophageal echocardiography (TOE) probe insertion in anaesthetised patients can cause pharyngeal and oesophageal injuries. Kim et al. have shown that insertion assisted by a Macintosh laryngoscope can reduce such complications but it may sometimes be difficult to observe the passage of a TOE probe. The...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/EJA.0000000000000367

    authors: Ishida T,Kiuchi C,Sekiguchi T,Tsujimoto T,Kawamata M

    更新日期:2016-04-01 00:00:00

  • How to inform a morbidly obese patient on the specific risk to develop postoperative pulmonary complications using evidence-based methodology.

    abstract:BACKGROUND AND OBJECTIVE:Patients have the right to be informed about the expected benefits and risks of medical and surgical procedures. Ideally this information should be scientifically based and presented to the patient in time. In morbidly obese patient undergoing general anaesthesia, postoperative pulmonary compli...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,meta分析

    doi:10.1017/S0265021505002073

    authors: Flier S,Knape JT

    更新日期:2006-02-01 00:00:00

  • Preoperative oral dextromethorphan vs. clonidine to prevent tourniquet-induced cardiovascular responses in orthopaedic patients under general anaesthesia.

    abstract:BACKGROUND AND OBJECTIVE:Preoperative oral dextromethorphan and intravenous clonidine attenuate arterial pressure and heart rate increases during tourniquet inflation under general anaesthesia. The effect of preoperative oral clonidine on these variables has not been investigated. METHODS:We designed this study to com...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1017/S0265021506002055

    authors: Honarmand A,Safavi MR

    更新日期:2007-06-01 00:00:00

  • Effects of hyperventilation on cerebral oxygen saturation estimated using near-infrared spectroscopy: A randomised comparison between propofol and sevoflurane anaesthesia.

    abstract:BACKGROUND:Near-infrared spectroscopy estimates cerebral regional tissue oxygen saturation (rSO2), which may decrease under hyperventilation. Propofol and sevoflurane act differently on cerebral blood vessels. Consequently, cerebral blood flow during hyperventilation with propofol and sevoflurane anaesthesia may differ...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/EJA.0000000000000507

    authors: Ishiyama T,Kotoda M,Asano N,Ikemoto K,Shintani N,Matsuoka T,Matsukawa T

    更新日期:2016-12-01 00:00:00

  • Comparison of inhalation induction with isoflurane or halothane in children.

    abstract::Thirty-six children (mean age 2.4 years) premedicated with oral chloral hydrate 70 mg kg-1 and atropine 0.03 mg kg-1 were anaesthetized with either 3.75% isoflurane or 2.5% halothane in 70% nitrous oxide in oxygen. The eyelash reflex disappeared in 39 +/- 7 s (mean +/- SD) with isoflurane and in 56 +/- 16 s with halot...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Lindgren L,Randell T,Saarnivaara L

    更新日期:1991-01-01 00:00:00

  • Neurotoxicity with single dose intrathecal midazolam administration.

    abstract:BACKGROUND AND OBJECTIVE:The aim of study was to investigate the electron microscopic changes in the medulla of the spinal cord that occur with intrathecal midazolam administration. METHODS:Twenty-eight albino rabbits of New Zealand type were randomized into two groups. Following anaesthesia, 16 rabbits were given 300...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1017/S0265021505001547

    authors: Ugur B,Basaloglu K,Yurtseven T,Ates U,Aydin ON,Ozenç D,Yurtseven M,Gürel A

    更新日期:2005-12-01 00:00:00

  • Bilateral paravertebral somatic nerve block for ventral hernia repair.

    abstract:BACKGROUND AND OBJECTIVE:Unilateral paravertebral nerve blockade has been reported to produce excellent afferent nerve block, reduce the incidence of postoperative nausea and vomiting, and reduce hospital stay following inguinal hernia repair. The aim was to compare the use of bilateral paravertebral blocks to regular ...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1017/s0265021502000352

    authors: Naja Z,Ziade MF,Lönnqvist PA

    更新日期:2002-03-01 00:00:00

  • Emergency intubation with the Combitube in two cases of difficult airway management.

    abstract::The airway was managed successfully in two cases of difficult intubation using the Combitube, a new device for emergency intubation, which combines the functions of an oesophageal obturator airway and a conventional endotracheal airway. One patient could not be intubated due to lockjaw; in the other patient, the vocal...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:

    authors: Staudinger T,Tesinsky P,Klappacher G,Brugger S,Rintelen C,Locker G,Weiss K,Frass M

    更新日期:1995-03-01 00:00:00

  • Sensory blockade after thoracic paravertebral injection of ropivacaine or bupivacaine.

    abstract:BACKGROUND AND OBJECTIVE:No clinical trials comparing the characteristics of sensory blockade caused by various local anaesthetics in thoracic paravertebral blockade have been published. The aim of this prospective study was a clinical assessment of sensory blockade after paravertebral injection of ropivacaine or bupiv...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1017/S0265021506000561

    authors: Hura G,Knapik P,Misiołek H,Krakus A,Karpe J

    更新日期:2006-08-01 00:00:00

  • An evaluation of capnography monitoring during the apnoea test in brain-dead patients.

    abstract:BACKGROUND AND OBJECTIVE:Diagnosis of brain death usually requires the absence of spontaneous respiratory movements during the apnoea test and an arterial carbon dioxide partial pressure above 60 mmHg. On the other hand, although capnography (end-tidal CO(2)) is currently monitored in intensive care unit patients, it h...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章

    doi:10.1017/S0265021507000725

    authors: Vivien B,Amour J,Nicolas-Robin A,Vesque M,Langeron O,Coriat P,Riou B

    更新日期:2007-10-01 00:00:00

  • Changes in resistances of endotracheal tubes with reductions in the cross-sectional area.

    abstract:BACKGROUND AND OBJECTIVES:Partial obstruction of endotracheal tubes due to accumulation of secretions and mucus plugs can increase the tube resistance and subsequently impose increased resistive load on the patient. This study was performed to determine the changes in the resistance of endotracheal tubes of sizes 7.5, ...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1017/S0265021507003134

    authors: El-Khatib MF,Husari A,Jamaleddine GW,Ayoub CM,Bou-Khalil P

    更新日期:2008-04-01 00:00:00

  • Complications associated with 27 031 ultrasound-guided axillary brachial plexus blocks: a web-based survey of 36 French centres.

    abstract:BACKGROUND:Ultrasound guidance improves the efficacy of peripheral nerve blocks, reducing performance time and local anaesthetic doses. It should also reduce the risk of systemic toxicity of local anaesthetic and nerve injuries. OBJECTIVE:The primary objective of this prospective study was to estimate the incidence of...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,多中心研究

    doi:10.1097/EJA.0000000000000063

    authors: Ecoffey C,Oger E,Marchand-Maillet F,Cimino Y,Rannou JJ,Beloeil H,SOS French Regional Anaesthesia Hotline.

    更新日期:2014-11-01 00:00:00

  • Comparison of fresh frozen plasma vs. coagulation factor concentrates for reconstitution of blood: An in vitro study.

    abstract:BACKGROUND:Many trauma centres have adopted the administration of fixed ratios of packed red blood cells (PRBCs), platelet concentrates and fresh frozen plasma (FFP) for bleeding patients. However, the haemostatic efficacy of this concept is not well proven. OBJECTIVE:Our objective was to characterise the haemostatic ...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0000000000001202

    authors: Gratz J,Ponschab M,Iapichino GE,Schlimp CJ,Cadamuro J,Grottke O,Zipperle J,Oberladstätter D,Gabriel C,Ziegler B,Schöchl H

    更新日期:2020-10-01 00:00:00

  • Bilateral phaeochromocytomas in pregnancy: anaesthetic management of combined caesarean section and tumour removal.

    abstract::A 25-year-old primigravida with bilateral phaeochromocytomas was managed from 6 weeks' gestation until 2.5 years following combined Caesarean section and removal of adrenal tumours. Pre-operative alpha-blockade was achieved by oral prazosin without deleterious effects. Intra-operative management comprised neuroleptana...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:

    authors: Pinaud M,Souron R,Le Neel JC,Lopes P,Murat A,L'hoste F

    更新日期:1985-12-01 00:00:00