Abstract:
BACKGROUND AND OBJECTIVE:The study investigated the effect of intravenous dexmedetomidine on brachial plexus block in patients with end-stage renal disease sedated with dexmedetomidine or midazolam for the formation of arteriovenous fistula. METHODS:A supraclavicular brachial plexus block was performed in 68 patients scheduled for an arteriovenous fistula formation. A successful block was achieved in 64 patients (94%). Sixty-four patients received either dexmedetomidine (loading dose 1 microg kg 10 min followed by infusion of 0.2-0.7 microg kg h) or midazolam (bolus dose 0.04 mg kg followed by infusion of 0.04-0.08 mg kg h). Three patients were excluded during the study. Finally, 61 patients were analysed, 32 in the dexmedetomidine group and 29 in the midazolam group. Administration of the study drug was started after achievement of a complete block. The duration of the motor and sensory block was assessed. RESULTS:The motor and sensory block was longer in the dexmedetomidine group (11.9 +/- 3.8 vs. 9.4 +/- 3.4 h, P = 0.0085 and 9.4 +/- 3.4 vs. 7.3 +/- 2.8 h, P = 0.030, respectively). CONCLUSION:A systemic administration of dexmedetomidine prolongs the duration of brachial plexus block.
journal_name
Eur J Anaesthesioljournal_title
European journal of anaesthesiologyauthors
Rutkowska K,Knapik P,Misiolek Hdoi
10.1097/EJA.0b013e32832a2244subject
Has Abstractpub_date
2009-10-01 00:00:00pages
851-5issue
10eissn
0265-0215issn
1365-2346journal_volume
26pub_type
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journal_title:European journal of anaesthesiology
pub_type: 杂志文章,评审
doi:
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journal_title:European journal of anaesthesiology
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journal_title:European journal of anaesthesiology
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:European journal of anaesthesiology
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journal_title:European journal of anaesthesiology
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更新日期:1986-05-01 00:00:00
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journal_title:European journal of anaesthesiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1984-09-01 00:00:00
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journal_title:European journal of anaesthesiology
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更新日期:2011-11-01 00:00:00
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journal_title:European journal of anaesthesiology
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更新日期:1986-11-01 00:00:00
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journal_title:European journal of anaesthesiology
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journal_title:European journal of anaesthesiology
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pub_type: 杂志文章,随机对照试验
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journal_title:European journal of anaesthesiology
pub_type: 杂志文章
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journal_title:European journal of anaesthesiology
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