Dynamic hyperinflation and intrinsic PEEP during mechanical ventilation.

Abstract:

:Dynamic hyperinflation, also called intrinsic PEEP (PEEPi,) occurs particularly when high tidal volumes or high respiratory rates are used during mechanical ventilation, although the phenomenon does occur at normal tidal volumes. It is not identified using existing monitoring such as the airway pressure but can be identified by occlusion of the expiratory port before the onset of the next positive pressure breath. Many factors contribute to PEEPi which has unfavourable effects on respiratory muscle activity. Inhomogenicity of the time constants is a major aetiological factor. Fine tuning of positive pressure ventilation, using low tidal volumes, short inspiratory times and adequate inspired oxygen are required. External PEEP, up to but not exceeding PEEPi, may be advisable. PEEP may be used therapeutically to improve gas exchange by inverse ratio ventilation or high frequency jet ventilation.

journal_name

Eur J Anaesthesiol

authors

Romand JA,Suter PM

subject

Has Abstract

pub_date

1994-01-01 00:00:00

pages

25-8

issue

1

eissn

0265-0215

issn

1365-2346

journal_volume

11

pub_type

杂志文章,评审
  • Cardiovascular responses and airway complications following awake nasal intubation with blind intubation device and fibreoptic bronchoscope: a randomized controlled study.

    abstract:BACKGROUND AND OBJECTIVE:The blind intubation device (BID) was introduced for awake nasotracheal intubation recently. The aim of this study was to compare the cardiovascular responses and associated airway complications of fibreoptic bronchoscope (FOB) with those of BID. The intubation attempts and intubation time were...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/EJA.0b013e328332845a

    authors: Sun Y,Liu JX,Jiang H,Zhu YS,Xu H,Huang Y

    更新日期:2010-05-01 00:00:00

  • Evaluation of augmented pulse pressure variation using the Valsalva manoeuvre as a predictor of fluid responsiveness under open-chest conditions: A prospective observational study.

    abstract:BACKGROUND:Pulse pressure variation (PPV) is a well known dynamic preload indicator of fluid responsiveness. However, its usefulness in open-chest conditions remains controversial. OBJECTIVE:We evaluated whether augmented PPV during a Valsalva manoeuvre can predict fluid responsiveness after sternotomy. DESIGN:A pros...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章

    doi:10.1097/EJA.0000000000000613

    authors: Min JJ,Kim TK,Lee JH,Park J,Cho HS,Kim WS,Lee YT

    更新日期:2017-05-01 00:00:00

  • Predictors of successful neuraxial block: a prospective study.

    abstract:BACKGROUND AND OBJECTIVE:The epidural and subarachnoid spaces should be identified at the first attempt, since multiple punctures increase the risk of postdural puncture headache, epidural haematoma and neural trauma. The study aimed to describe the predictors of successful neuraxial blocks at the first attempt. METHO...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章

    doi:10.1017/s0265021502000716

    authors: de Filho GR,Gomes HP,da Fonseca MH,Hoffman JC,Pederneiras SG,Garcia JH

    更新日期:2002-06-01 00:00:00

  • Low anaesthetic waste gas concentrations in postanaesthesia care unit: A prospective observational study.

    abstract:BACKGROUND:Volatile anaesthetics are a potential hazard during occupational exposure, pregnancy or in individuals with existing disposition to malignant hyperthermia. Anaesthetic waste gas concentration in postanaesthesia care units (PACU) has rarely been investigated. OBJECTIVE(S):The current study aims to assess con...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0000000000000785

    authors: Heiderich S,Thoben C,Dennhardt N,Koppert W,Krauß T,Sümpelmann R,Zimmermann S,Klingler W

    更新日期:2018-07-01 00:00:00

  • Fentanyl pre-treatment does not affect the pharmacokinetic profile of an induction dose of propofol in adults.

    abstract::The initial disposition of propofol was reported to change when the administration was preceded by fentanyl. The pharmacokinetic profile of the induction dose of propofol (2 mg kg-1 body weight) was studied in 20 ASA I patients randomly allocated to receive fentanyl 1.5 microgram kg-1 (n = 12) or not (n = 8). Anaesthe...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: De Gasperi A,Cristalli A,Noé L,Sabbadini D,Mazza E,Prosperi M,Fantini G,Crespi AM,Rezzani S

    更新日期:1994-03-01 00:00:00

  • Morphine administration at reperfusion fails to improve postischaemic cardiac function but limits myocardial injury probably via heat-shock protein 27 phosphorylation.

    abstract:BACKGROUND AND OBJECTIVES:We explored the effects of morphine administration during reperfusion period after an index ischaemia as well as potential molecular mechanisms underlying this response. This is of important clinical value, as morphine is used routinely in cardiovascular anaesthesia and in the emergency manage...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0b013e32832a225a

    authors: Mourouzis I,Saranteas T,Perimenis P,Tesseromatis C,Kostopanagiotou G,Pantos C,Cokkinos DV

    更新日期:2009-07-01 00:00:00

  • Post-operative course after conventional or laparoscopic gastroplasty in morbidly obese patients.

    abstract::The post-operative period is particularly dangerous for obese patients. The aim of this study was to compare the immediate post-operative course after either laparoscopic or open gastroplasty. We studied retrospectively 20 and 14 consecutive patients who underwent laparoscopic or open adjustable silicone gastric bandi...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2346.1999.00510.x

    authors: Juvin P,Marmuse JP,Delerme S,Lecomte P,Mantz J,Demetriou M,Desmonts JM

    更新日期:1999-06-01 00:00:00

  • Mivacurium or vecuronium for muscular relaxation in day-case surgery.

    abstract::Anaesthetic agents for day-case surgery ideally should have a short duration of action. This study was designed to compare the efficacy and safety of mivacurium and vecuronium for healthy adults undergoing dental day-case surgery. Thirty fit healthy adult patients (ASA I or II) randomly received either mivacurium 0.15...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1365-2346.1994.00207.x

    authors: Rigg JD,Wilson AC,Pollard BJ

    更新日期:1997-11-01 00:00:00

  • A comparative study of patient-controlled epidural diamorphine, subcutaneous diamorphine and an epidural diamorphine/bupivacaine combination for postoperative pain.

    abstract::This randomized double blind study investigates the relative efficacies of controlled analgesia (PCA) regimens in three different patient groups: epidural diamorphine 2.5 mg followed by PCA bolus 1 mg with a 20-min lockout (Gp1), subcutaneous diamorphine 2.5 mg followed by PCA bolus with a 10-min lockout period (Gp2) ...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1365-2346.2000.00647.x

    authors: Gopinathan C,Sockalingham I,Fung MA,Peat S,Hanna MH

    更新日期:2000-03-01 00:00:00

  • The use of ultrasound to guide time-critical cannula tracheotomy when anterior neck airway anatomy is unidentifiable.

    abstract:BACKGROUND AND OBJECTIVE:Transtracheal or transcricothyroid placement of a cannula is a practice used in a number of aspects of airway management in anaesthesia and intensive care. In this study, we aimed to investigate whether the use of ultrasound will facilitate cannula placement in a time-critical situation in pati...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/EJA.0b013e328344b4e1

    authors: Dinsmore J,Heard AM,Green RJ

    更新日期:2011-07-01 00:00:00

  • Development and performance testing of the low-cost, 3D-printed, smartphone-compatible 'Tansen Videolaryngoscope' vs. Pentax-AWS videolaryngoscope vs. direct Macintosh laryngoscope: A manikin study.

    abstract:BACKGROUND:While videolaryngoscopes help in the management of difficult airways, they remain too expensive for those with limited resources. We have developed a robust, re-usable, low-cost videolaryngoscope at United Mission Hospital Tansen, Nepal, by combining a smartphone-compatible endoscope capable of capturing sti...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0000000000001264

    authors: Lambert CT,John SC,John AV

    更新日期:2020-11-01 00:00:00

  • Arterial pressure waveform analysis versus thermodilution cardiac output measurement during open abdominal aortic aneurysm repair: a prospective observational study.

    abstract:BACKGROUND:Arterial pressure waveform analysis enables continuous, minimally invasive measurement of cardiac output. Haemodynamic instability compromises the reliability of the technique and a means of maintaining accurate measurement in this circumstance would be useful. OBJECTIVES:To investigate the accuracy, precis...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0000000000000160

    authors: Montenij LJ,Buhre WF,de Jong SA,Harms JH,van Herwaarden JA,Kruitwagen CL,de Waal EE

    更新日期:2015-01-01 00:00:00

  • Assessment of ondansetron and droperidol for the prevention of post-operative nausea and vomiting after cholecystectomy and minor gynaecological surgery performed by laparoscopy.

    abstract::The anti-emetic effects of ondansetron and droperidol were evaluated in 134 ASA Grade I and II female patients, scheduled for laparoscopic cholecystectomy and minor gynaecological laparoscopic surgery, who were randomly assigned to receive ondansetron 4 mg or droperidol 75 micrograms kg-1 intravenously immediately aft...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1365-2346.1999.00581.x

    authors: Swiatkowski J,Goral A,Dzieciuch JA,Przesmycki K

    更新日期:1999-11-01 00:00:00

  • Metamizole for postoperative pain therapy in 1177 children: A prospective, multicentre, observational, postauthorisation safety study.

    abstract:BACKGROUND:Due to possible serious adverse drug reactions (ADRs), the use of metamizole for postoperative pain therapy in children is a subject of debate. Safety studies with large sample sizes have not been published as yet. OBJECTIVE:The aim of this study was to evaluate the use of metamizole in children aged up to ...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,多中心研究

    doi:10.1097/EJA.0000000000000272

    authors: Fieler M,Eich C,Becke K,Badelt G,Leimkühler K,Messroghli L,Boethig D,Sümpelmann R

    更新日期:2015-12-01 00:00:00

  • Neostigmine-based reversal of intermediate acting neuromuscular blocking agents to prevent postoperative residual paralysis: A systematic review.

    abstract:BACKGROUND:Neostigmine is widely used to antagonise residual paralysis. Over the last decades, the benchmark of acceptable neuromuscular recovery has increased progressively to a train-of-four (TOF) ratio of at least 0.9. Raising this benchmark may impact on the efficacy of neostigmine. OBJECTIVE(S):The systematic rev...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0000000000000741

    authors: Tajaate N,Schreiber JU,Fuchs-Buder T,Jelting Y,Kranke P

    更新日期:2018-03-01 00:00:00

  • Monitoring depth of anaesthesia: is it worth the effort?

    abstract::In this review paper, the authors critically analyse the use of a number of depth of anaesthesia monitors in light of the most recent literature and their own clinical experience. There appears to be increasing evidence that anaesthesia depth monitors reduce the incidence of unexpected intraoperative awareness and als...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,评审

    doi:10.1017/s0265021504006027

    authors: Bonhomme V,Hans P

    更新日期:2004-06-01 00:00:00

  • Comparison of a continuous noninvasive arterial pressure device with invasive measurements in cardiovascular postsurgical intensive care patients: a prospective observational study.

    abstract:BACKGROUND:Arterial pressure monitoring using the a continuous noninvasive arterial pressure (CNAP) device during general anaesthesia is known to be interchangeable with continuous invasive arterial pressure (CIAP) monitoring. Agreement with invasive measurements in cardiovascular postsurgical intensive care patients h...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章

    doi:10.1097/EJA.0000000000000136

    authors: Ilies C,Grudev G,Hedderich J,Renner J,Steinfath M,Bein B,Haake N,Hanss R

    更新日期:2015-01-01 00:00:00

  • Comparison of Bullard and Airtraq laryngoscopes with conventional laryngoscopy in a manikin study of simulated difficult intubation.

    abstract:BACKGROUND:When airway management is difficult, various measures can be taken to facilitate tracheal intubation. The Bullard and Airtraq laryngoscopes were developed for this purpose. We hypothesised that the Bullard and Airtraq laryngoscopes would perform better than a conventional laryngoscope in the management of a ...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/EJA.0b013e328354b22c

    authors: Legrand MA,Steinmann D,Priebe HJ,Mols G

    更新日期:2012-07-01 00:00:00

  • Sensory blockade after thoracic paravertebral injection of ropivacaine or bupivacaine.

    abstract:BACKGROUND AND OBJECTIVE:No clinical trials comparing the characteristics of sensory blockade caused by various local anaesthetics in thoracic paravertebral blockade have been published. The aim of this prospective study was a clinical assessment of sensory blockade after paravertebral injection of ropivacaine or bupiv...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1017/S0265021506000561

    authors: Hura G,Knapik P,Misiołek H,Krakus A,Karpe J

    更新日期:2006-08-01 00:00:00

  • Warming before and after epidural block before general anaesthesia for major abdominal surgery prevents perioperative hypothermia: A randomised controlled trial.

    abstract:BACKGROUND:Epidural analgesia (EDA) is known to be an independent risk factor for perioperative hypothermia and its many known adverse effects. Combined general and epidural anaesthesia decreases intraoperative core temperature more rapidly than general anaesthesia alone. Hence, adequate warming procedures are needed f...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/EJA.0000000000000369

    authors: Horn EP,Bein B,Broch O,Iden T,Böhm R,Latz SK,Höcker J

    更新日期:2016-05-01 00:00:00

  • S100B protein and neuron-specific enolase as predictors of cognitive dysfunction after coronary artery bypass graft surgery: A prospective observational study.

    abstract:BACKGROUND:Postoperative cognitive dysfunction (POCD) may be related to the systemic inflammatory response and an increase in serum markers of brain injury such as S100B protein and neuron-specific enolase (NSE). OBJECTIVE:The study aims to evaluate the association between POCD and serum levels of S100B and NSE after ...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0000000000000450

    authors: Silva FP,Schmidt AP,Valentin LS,Pinto KO,Zeferino SP,Oses JP,Wiener CD,Otsuki DA,Tort AB,Portela LV,Souza DO,Auler JO Jr,Carmona MJ

    更新日期:2016-09-01 00:00:00

  • Thoracolumbar epidural anaesthesia and isoflurane to prevent hypertension and tachycardia in patients undergoing abdominal aortic surgery.

    abstract::Cardiovascular and hormonal responses to reconstructive abdominal aortic surgery were studied in 20 patients anaesthetized either with moderate-dose fentanyl (20 micrograms kg-1) combined with isoflurane, nitrous oxide and oxygen (n = 10), or with thoracolumbar epidural bupivacaine combined with isoflurane, nitrous ox...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Kataja J

    更新日期:1991-11-01 00:00:00

  • Cognitive decline after carotid endarterectomy: Systematic review and meta-analysis.

    abstract:BACKGROUND:Postoperative cognitive decline (pCD) occurs frequently (6 to 30%) after carotid endarterectomy (CEA), although there are no exact estimates and risk factors are still unclear. OBJECTIVE:The objective of this study was to determine pCD incidence and risk factors in CEA patients. DESIGN:We performed a syste...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0000000000001130

    authors: Aceto P,Lai C,De Crescenzo F,Crea MA,Di Franco V,Pellicano GR,Perilli V,Lai S,Papanice D,Sollazzi L

    更新日期:2020-11-01 00:00:00

  • Gastric mucosal-to-end-tidal PCO2 difference during major abdominal surgery: influence of the arterial-to-end-tidal PCO2 difference?

    abstract:BACKGROUND AND OBJECTIVE:Because gastric mucosal PCO2 must be referenced to arterial values via a gastric-to-arterial PCO2 gap (Pg-aCO2), the gastric-to-end-tidal PCO2 difference (Pg-ETCO2) may be proposed as a surrogate method to monitor Pg-aCO2. However, the influence of arterial-to-end-tidal PCO2 (Pa-ETCO2) on its v...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1017/s0265021503000279

    authors: Lebuffe G,Onimus T,Vallet B

    更新日期:2003-02-01 00:00:00

  • A case for competency-based anaesthesiology training with entrustable professional activities: an agenda for development and research.

    abstract::Competency frameworks are based on what are considered to be the general essential qualities of a doctor. Competencies, being behavioural descriptors, need a strong link to clinical practice to allow trainers to observe and then use them in assessing trainees' performance. The emerging concept of entrustable professio...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,评审

    doi:10.1097/EJA.0000000000000109

    authors: Jonker G,Hoff RG,Ten Cate OT

    更新日期:2015-02-01 00:00:00

  • Effect of parecoxib sodium on postoperative shivering: a randomised, double-blind clinical trial.

    abstract:BACKGROUND:Postoperative shivering is one of the most common complications in patients recovering from general anaesthesia. Although a variety of pharmacological therapies have been used to control postoperative shivering, no ideal drug has been found to date. OBJECTIVES:The aim of this study was to compare the effica...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/01.EJA.0000436684.94403.1e

    authors: Li X,Zhou M,Xia Q,Li W,Zhang Y

    更新日期:2014-04-01 00:00:00

  • The PediaSat continuous central SvO2 monitoring system does not reliably indicate state or course of central venous oxygenation.

    abstract:BACKGROUND AND OBJECTIVE:The present study compares the accuracy of a new continuous venous oxygenation monitoring system (PediaSat Oximetry Catheter) with laboratory blood oximetry in paediatric surgical patients. METHODS:Children and adolescents undergoing cardiac, orthopaedic or craniofacial surgery with major bloo...

    journal_title:European journal of anaesthesiology

    pub_type: 临床试验,杂志文章

    doi:10.1097/EJA.0b013e32833bf5c5

    authors: Baulig W,Béttex D,Bürki C,Schmitz A,Spielmann N,Woitzek K,Weiss M

    更新日期:2010-08-01 00:00:00

  • Pectoral nerve blocks for breast surgery: A meta-analysis.

    abstract:BACKGROUND:Pectoral nerve blocks (PECS block) might be an interesting new regional anaesthetic technique in patients undergoing breast surgery. OBJECTIVE:The aim of this meta-analysis was to investigate postoperative pain outcomes and adverse events of a PECS block compared with no treatment, sham treatment or other r...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1097/EJA.0000000000001403

    authors: Meißner M,Austenfeld E,Kranke P,Zahn PK,Pogatzki-Zahn EM,Meyer-Frießem CH,Weibel S,Schnabel A

    更新日期:2020-11-24 00:00:00

  • Increased production of nitric oxide metabolites in the hippocampus under isoflurane anaesthesia in rats.

    abstract::There is disagreement concerning the role of nitric oxide (NO) in general anaesthesia. The present study was conducted to determine whether the anaesthetic drug isoflurane alters levels of NO metabolites, NOx (NO2 and NO3), in the hippocampus of rats during and after anaesthesia. Results showed resting hippocampal NOx...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章

    doi:10.1046/j.1365-2346.1999.00459.x

    authors: Matsuoka H,Watanabe Y,Isshiki A,Quock RM

    更新日期:1999-04-01 00:00:00

  • Platelet function assessed by whole-blood aggregometry in patients undergoing non-cardiac surgery.

    abstract:BACKGROUND:The risk/benefit of continuing low-dose acetylsalicylic acid (aspirin) for secondary prevention in the perioperative period is still debated. The primary aim of this study was to determine the effect of acetylsalicylic acid compared with placebo on platelet function in the perioperative period. METHODS:This...

    journal_title:European journal of anaesthesiology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/EJA.0b013e32834448ed

    authors: Oscarsson A,Öster S,Fredrikson M,Lindahl TL,Eintrei C

    更新日期:2011-05-01 00:00:00