Abstract:
:The effect of the duration of stabilization of control responses on the onset and duration of clinical relaxation of suxamethonium 1 mg kg-1 and rocuronium 0.6 mg kg-1 were investigated in 90 patients. The control responses were allowed to stabilize for 1, 5, 10, 15 or 20 min prior to administration of rocuronium and for 1, 5, 10 or 15 min prior to suxamethonium. The mean onset time for rocuronium decreased from 150 to 46 s as the duration of stabilization increased from 1 to 20 min (P < 0.001) although the maximal effect was observed within the first 5 min. The average duration of clinical relaxation also increased from 25 to 40 min (P < 0.001). No effect was observed for either variable in the case of suxamethonium.
journal_name
Eur J Anaesthesioljournal_title
European journal of anaesthesiologyauthors
Symington MJ,McCoy EP,Mirakhur RK,Kumar Ndoi
10.1046/j.1365-2346.1996.d01-379.xsubject
Has Abstractpub_date
1996-07-01 00:00:00pages
377-80issue
4eissn
0265-0215issn
1365-2346journal_volume
13pub_type
临床试验,杂志文章,随机对照试验abstract:CONTEXT:Perioperative oral carbohydrate intake is beneficial to general surgery patients. Total hip arthroplasty is a common surgical procedure, and even a moderate improvement in patient outcome could have a significant effect on the resources needed for these patients. However, few studies have focused on the effects...
journal_title:European journal of anaesthesiology
pub_type: 杂志文章,随机对照试验
doi:10.1097/EJA.0b013e3283525ba9
更新日期:2012-06-01 00:00:00
abstract::The hypothesis that calcium channel blockers can potentiate and prolong the anti-nociceptive effects of opioids was tested. Forty-five men scheduled for aorto-coronary bypass operation received fentanyl according to their individual demands (haemodynamics, clinical parameters). The patients were allocated at random in...
journal_title:European journal of anaesthesiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1987-11-01 00:00:00
abstract::Morbidly obese patients present with excess fatty tissue externally on the breast, neck, thoracic wall and abdomen and internally in the mouth, pharynx and abdomen. This excess tissue tends to make access (intubation, tracheostomy) to and patency (during sedation or mask ventilation) of the upper airway and the functi...
journal_title:European journal of anaesthesiology
pub_type: 杂志文章,评审
doi:10.1097/EJA.0b013e32833d91aa
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:When continuous infusions of neuromuscular blocking drugs are administered during lengthy interventions and no routine antagonism of their effects is applied, there is a dramatic incidence of residual curarization. We have examined whether the use of neuromuscular transmission monitoring result...
journal_title:European journal of anaesthesiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1017/s026502150300142x
更新日期:2003-11-01 00:00:00
abstract:BACKGROUND:Arterial pressure monitoring using the a continuous noninvasive arterial pressure (CNAP) device during general anaesthesia is known to be interchangeable with continuous invasive arterial pressure (CIAP) monitoring. Agreement with invasive measurements in cardiovascular postsurgical intensive care patients h...
journal_title:European journal of anaesthesiology
pub_type: 临床试验,杂志文章
doi:10.1097/EJA.0000000000000136
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:When administered as a continuous infusion, ketamine is known to be a potent analgesic and general anaesthetic. Recent studies suggest that a single low-dose administration of ketamine can provide a long-lasting effect on mood, but its effects when given in the postoperative period have not been studied. OB...
journal_title:European journal of anaesthesiology
pub_type: 杂志文章,随机对照试验
doi:10.1097/EJA.0000000000000860
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:In isolated-perfused lungs of lipopolysaccharide (LPS)-challenged rats, vasodilatation to inhaled nitric oxide (NO) is impaired. Inhibition of nitric oxide synthase 2 (NOS2) by aminoguanidine (AG) prevented hyporesponsiveness to inhaled NO. Here, we investigated whether NOS2-mediated nitrite/n...
journal_title:European journal of anaesthesiology
pub_type: 杂志文章
doi:10.1017/S0265021506001463
更新日期:2007-04-01 00:00:00
abstract:BACKGROUND:The risk/benefit of continuing low-dose acetylsalicylic acid (aspirin) for secondary prevention in the perioperative period is still debated. The primary aim of this study was to determine the effect of acetylsalicylic acid compared with placebo on platelet function in the perioperative period. METHODS:This...
journal_title:European journal of anaesthesiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/EJA.0b013e32834448ed
更新日期:2011-05-01 00:00:00
abstract::In order to compare the neuromuscular effects following rocuronium 0.6 mg kg-1 and atracurium 0.5 mg kg-1 30 children aged from 18 to 67 months were studied under the same anaesthetic conditions. After induction of anaesthesia with etomidate and fentanyl, neuromuscular blockade was monitored by recording the electromy...
journal_title:European journal of anaesthesiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.1365-2346.1998.00294.x
更新日期:1998-05-01 00:00:00
abstract:BACKGROUND:Septic encephalopathy is believed to be a result of neuro-inflammation possibly triggered by endotoxins, such as lipopolysaccharides (LPS). Modulation of the immune system is a property of volatile anaesthetics. OBJECTIVE:We aimed to investigate the systemic and cerebral inflammatory response in a LPS-induc...
journal_title:European journal of anaesthesiology
pub_type: 杂志文章
doi:10.1097/EJA.0000000000000668
更新日期:2017-11-01 00:00:00
abstract::Dynamic hyperinflation, also called intrinsic PEEP (PEEPi,) occurs particularly when high tidal volumes or high respiratory rates are used during mechanical ventilation, although the phenomenon does occur at normal tidal volumes. It is not identified using existing monitoring such as the airway pressure but can be ide...
journal_title:European journal of anaesthesiology
pub_type: 杂志文章,评审
doi:
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:This study compares three modes of patient-controlled epidural analgesia in parturients during labour. METHODS:Eighty-four women were randomized to one of three groups. The epidural solution used in all the three groups was 0.1% bupivacaine with fentanyl 2 microg mL(-1). Patients were able to...
journal_title:European journal of anaesthesiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1017/s0265021505000074
更新日期:2005-01-01 00:00:00
abstract::A 25-year-old primigravida with bilateral phaeochromocytomas was managed from 6 weeks' gestation until 2.5 years following combined Caesarean section and removal of adrenal tumours. Pre-operative alpha-blockade was achieved by oral prazosin without deleterious effects. Intra-operative management comprised neuroleptana...
journal_title:European journal of anaesthesiology
pub_type: 杂志文章
doi:
更新日期:1985-12-01 00:00:00
abstract::Malignant hyperthermia is an autosomal-dominant inherited disorder of the skeletal muscle cell characterized by a hypermetabolic response to all commonly used inhalational anaesthetics and depolarizing muscle relaxants. The clinical syndrome includes muscle rigidity, hypercapnia, tachycardia and myoglobinuria as resul...
journal_title:European journal of anaesthesiology
pub_type: 杂志文章,评审
doi:10.1046/j.1365-2346.2001.00888.x
更新日期:2001-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The effects of bicarbonated Ringer's solution were evaluated and compared with those of acetated Ringer's, lactated Ringer's and Ringer's solutions in partially hepatectomized rabbits. METHOD:Animals were randomly divided into six groups (n = 6 in each group): a sham-operated group, an operate...
journal_title:European journal of anaesthesiology
pub_type: 杂志文章
doi:10.1017/s0265021505001043
更新日期:2005-08-01 00:00:00
abstract::We report the case of a 33-year-old woman who developed a dense hemiplegia immediately after an uncomplicated general anaesthetic for diagnostic laparoscopy. She had a history of recurrent hemiplegic migraine with a strong family history. Her migraine was normally associated with visual disturbances and a unilateral h...
journal_title:European journal of anaesthesiology
pub_type: 杂志文章
doi:10.1046/j.1365-2346.1998.00368.x
更新日期:1998-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:We have evaluated the effects of propofol and its relationship with K+ channels on human isolated umbilical vessels. METHODS:Umbilical vessel rings were suspended in isolated organ baths containing Krebs-Ringer solution. In the first series of experiments the effect of propofol (10(-9)-10(-4) ...
journal_title:European journal of anaesthesiology
pub_type: 杂志文章
doi:10.1017/S0265021505001924
更新日期:2006-05-01 00:00:00
abstract::In this review paper, the authors critically analyse the use of a number of depth of anaesthesia monitors in light of the most recent literature and their own clinical experience. There appears to be increasing evidence that anaesthesia depth monitors reduce the incidence of unexpected intraoperative awareness and als...
journal_title:European journal of anaesthesiology
pub_type: 杂志文章,评审
doi:10.1017/s0265021504006027
更新日期:2004-06-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Adding opioid to spinal anaesthetic provides additional analgesia during the postoperative period. The purpose of this study was to determine the dose of intrathecal hydromorphone necessary to achieve postoperative pain relief after arthroscopic knee surgery. METHODS:In a prospective, double-b...
journal_title:European journal of anaesthesiology
pub_type: 杂志文章,随机对照试验
doi:10.1097/EJA.0b013e3283476055
更新日期:2012-01-01 00:00:00
abstract::From a family tragedy 20 years ago, ATLS has truly become an international trauma care program. Its success is demonstrated not only in the large number of physicians that have been trained, but also in the appearance of a number of affiliated courses with a similar structure, aimed at training medical, nursing, civil...
journal_title:European journal of anaesthesiology
pub_type: 杂志文章,评审
doi:10.1046/j.1365-2346.1996.00939.x
更新日期:1996-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:We investigated the following aspects of pharmacokinetic-guided total intravenous anaesthesia with remifentanil and propofol in patients undergoing surgical myocardial revascularization: anaesthetic efficacy, haemodynamic effects, impact on extubation of the trachea and analgesia after operatio...
journal_title:European journal of anaesthesiology
pub_type: 杂志文章
doi:10.1017/s0265021503000589
更新日期:2003-05-01 00:00:00
abstract::Fourteen fit young patients undergoing body surface surgery received an infusion of alfentanil at either 50 or 100 micrograms kg-1 hr-1 to supplement nitrous oxide anaesthesia. The alfentanil infusion was continued for two hours post-operatively at the lower rate of 20 micrograms kg-1 hr-1. Resting ventilation, carbon...
journal_title:European journal of anaesthesiology
pub_type: 临床试验,杂志文章
doi:
更新日期:1987-05-01 00:00:00
abstract:BACKGROUND:Hypoventilation is a major cause of morbidity and mortality in patients having procedures under sedation. Few clinical strategies have been evaluated to reduce intraoperative hypoventilation during surgical procedures under deep sedation. OBJECTIVE:The primary objective of this investigation was to examine ...
journal_title:European journal of anaesthesiology
pub_type: 杂志文章,随机对照试验
doi:10.1097/EJA.0000000000000025
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The laryngeal mask has become a widely accepted alternative to endotracheal intubation and mask ventilation. The laryngeal tube is a relatively new supraglottic airway device for airway management. We compared the new version of the laryngeal tube with the laryngeal mask. METHODS:In a randomiz...
journal_title:European journal of anaesthesiology
pub_type: 杂志文章,随机对照试验
doi:10.1017/S0265021507000129
更新日期:2007-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Astrocytes exposed to hypoxia produce pro-inflammatory cytokines and upregulate intercellular adhesion molecule-1 on cerebral endothelium. This study investigated the effects of midazolam on this response. METHODS:Mouse astrocytes were exposed to 4 h of hypoxia and 24 h of reoxygenation. Astro...
journal_title:European journal of anaesthesiology
pub_type: 杂志文章
doi:10.1017/S0265021506000652
更新日期:2006-09-01 00:00:00
abstract:BACKGROUND:Effective postoperative analgesia after caesarean section is important because it enables early ambulation and facilitates breast-feeding. Several case reports have shown that local anaesthetic injection around the quadratus lumborum muscle is effective in providing pain relief after various abdominal operat...
journal_title:European journal of anaesthesiology
pub_type: 杂志文章,随机对照试验
doi:10.1097/EJA.0000000000000299
更新日期:2015-11-01 00:00:00
abstract::We present a case of pulmonary embolism that occurred during the injection of lipiodol during transcatheter arterial chemoembolization under general anaesthesia. A 7-year-old child suffering from a large hepatoblastoma was admitted for arterial chemoembolization and carcinostatic administration. Pulmonary embolism due...
journal_title:European journal of anaesthesiology
pub_type: 杂志文章
doi:10.1046/j.1365-2346.2000.00759.x
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Postoperative cardiac surgery patients are usually sedated according to clinical sedation scores. Electrophysiological data derived from electroencephalography, such as the bispectral index (BIS), have been reported to assess and quantify the level of sedation, although experience in these pati...
journal_title:European journal of anaesthesiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/EJA.0b013e328335b2d4
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:For cannulation of the internal jugular vein (IJV), ultrasound increases the number of first pass successes and reduces the rate of mechanical complications. A frequent complication of IJV access is the accidental injury of the common carotid artery (CCA), which can be dangerous in some circums...
journal_title:European journal of anaesthesiology
pub_type: 杂志文章
doi:10.1097/EJA.0b013e328341a492
更新日期:2011-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:We assessed the analgesic efficacy of postoperative epidural infusions of ropivacaine 0.1 and 0.2% combined with sufentanil 1 microg mL(-1) in a prospective, randomized, double-blinded study. METHODS:Twenty-two ASA I-III patients undergoing elective total-knee replacement were included. Lumbar...
journal_title:European journal of anaesthesiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1017/s0265021502001096
更新日期:2002-09-01 00:00:00