Alfentanil infusions: relationship between pharmacokinetics and pharmacodynamics in man.

abstract：BACKGROUND AND OBJECTIVE:The study investigated the effect of intravenous dexmedetomidine on brachial plexus block in patients with end-stage renal disease sedated with dexmedetomidine or midazolam for the formation of arteriovenous fistula. METHODS:A supraclavicular brachial plexus block was performed in 68 patients ...

journal_title：European journal of anaesthesiology

authors： Rutkowska K,Knapik P,Misiolek H

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:In the perivascular sheath of the brachial plexus, the volume of anaesthetic solution determines the quality of anaesthetic cover. Fibrous septa may divide the perivascular space into compartments, leading to inadequate diffusion of the anaesthetic solution. The aim of our study was to obtain g...

journal_title：European journal of anaesthesiology

authors： Pippa P,Cuomo P,Panchetti A,Scarchini M,Poggi G,D'Arienzo M

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:It has been demonstrated that volatile anaesthetics have cardioprotective properties during open-heart procedures, especially when administered continuously. European Council Directive 93/42/EEC concerning medical devices bans the supplementary incorporation of anaesthetic vaporizers in the byp...

journal_title：European journal of anaesthesiology

authors： Prasser C,Zelenka M,Gruber M,Philipp A,Keyser A,Wiesenack C

更新日期：2008-02-01 00:00:00

abstract：:It is assumed that diabetic patients with uraemia have more complications at renal transplantation than those who are not diabetic. We compared the preoperative ECGs, and invasive perioperative haemodynamic and oxygenation parameters in 15 diabetic and 15 non-diabetic uraemic patients undergoing renal transplantation....

journal_title：European journal of anaesthesiology

authors： Norio K,Mäkisalo H,Isoniemi H,Groop PH,Pere P,Lindgren L

更新日期：2000-12-01 00:00:00

abstract：:The molecular mechanism of volatile anaesthetic action on presynaptic glutamate release is not clear. An inhibitory effect on voltage-gated calcium channels has been proposed. The present study examines the effect of isoflurane on cytosolic free calcium and synaptic glutamate release from isolated nerve terminals. Syn...

journal_title：European journal of anaesthesiology

authors： Larsen M,Valø ET,Berg-Johnsen J,Langmoen IA

更新日期：1998-03-01 00:00:00

abstract：:The effects of protamine (6 mg kg-1) injected after heparin (5 mg kg-1) have been studied in five groups of five New Zealand white rabbits. Group I was treated with the sequence heparin-protamine and group II with protamine alone. The animals of groups III and IV received respectively intravenous indomethacin (3 mg kg...

journal_title：European journal of anaesthesiology

authors： Nathan N,Aissa J,Benveniste J,Arnoux B

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Several approaches have been proposed for ultrasound-guided thoracic paravertebral block, but the best approach remains unclear. OBJECTIVE:We compared two ultrasound-guided in-plane approaches using a microconvex probe, transverse and parasagittal. We assessed whether either approach would facilitate succes...

journal_title：European journal of anaesthesiology

authors： Fujii T,Shibata Y,Shinya S,Nishiwaki K

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:the objective of this study was to assess whether antiemetic drugs metoclopramide and diphenhydramine, administered together as opposed to alone, can have better efficacy in preventing postoperative nausea and vomiting when added to patient-controlled morphine analgesia. PATIENTS AND METHODS:d...

journal_title：European journal of anaesthesiology

authors： Lu CW,Jean WH,Wu CC,Shieh JS,Lin TY

更新日期：2010-12-01 00:00:00

abstract：:A variety of laboratory and clinical studies clearly indicate that exposure to anaesthetic agents can lead to a pronounced protection of the myocardium against ischaemia-reperfusion injury. Several changes in the protein structure of the myocardium that may mediate this cardioprotection have been identified. Ischaemia...

journal_title：European journal of anaesthesiology

authors： Weber NC,Preckel B,Schlack W

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The effect of anaesthesia induced by intrathecal injection of 6.3% MgSO4 or 4% lidocaine on intracellular electrolyte homeostasis in spinal cord neurones of a rat model was investigated. METHODS:Intracellular Ca2+, Mg2+, Na+ and K+ concentrations were determined at different times after intrat...

journal_title：European journal of anaesthesiology

authors： Bahar M,Berman S,Chanimov M,Weissgarten J,Averbukh Z,Cohen ML,Grinshpon Y

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:ProSeal Laryngeal Mask Airway (PLMA) and Laryngeal Tube Suction (LTS), supraglottic airway devices allowing gastric drainage, were compared in this prospective, randomized study for airway management under conditions with elevated intra-abdominal pressure induced by capnoperitoneum. METHODS:Fi...

journal_title：European journal of anaesthesiology

authors： Roth H,Genzwuerker HV,Rothhaas A,Finteis T,Schmeck J

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The importance of monitoring the breathing pattern during sedation of children undergoing magnetic resonance scans is indicated in guidelines, but no appropriate magnetic resonance-compatible devices are available. We report preliminary findings from a technique referred to as remote pressure s...

journal_title：European journal of anaesthesiology

authors： Caldiroli D,Minati L

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Proinflammatory cytokines as well as nitric oxide (NO) play a major role in mediating the response to lipopolysaccharide (LPS). The present study tested the hypothesis that LPS induces proinflammatory cytokines in the lung via the Toll-like receptor 4 (TLR4)/CD14 signalling cascade. METHODS:Co...

journal_title：European journal of anaesthesiology

authors： Baumgarten G,Knuefermann P,Wrigge H,Putensen C,Stapel H,Fink K,Meyer R,Hoeft A,Grohé C

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Patients in cardiac surgery and critically ill patients often demonstrate either hypothermia or fever. In addition, owing to heart failure, they frequently require inotropic support. The relative effectiveness of modern inotropic agents at various temperatures has not yet been evaluated. Theref...

journal_title：European journal of anaesthesiology

authors： Rieg AD,Schroth SC,Grottke O,Hein M,Ackermann D,Rossaint R,Schälte G

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The quality of combined spinal-epidural anaesthesia mainly depends on accurate identification of the epidural space. The real-time ultrasound control of the procedure for puncture was therefore evaluated. METHODS:Thirty parturients scheduled for Caesarean section were randomized to three equal...

journal_title：European journal of anaesthesiology

authors： Grau T,Leipold RW,Fatehi S,Martin E,Motsch J

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Although the PROWESS trial demonstrated a mortality benefit, subsequent studies in different patient populations have not reproduced the effect. As a result, concerns have been expressed about the clinical effectiveness of drotrecogin alfa (activated). Therefore the aim of this audit was to rev...

journal_title：European journal of anaesthesiology

authors： Ridley S,Lwin A,Wyncoll D,Lippett S,Watson D,Gunning K,Higgins D

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:The isolated heart model is widely used for the assessment of coronary vascular response under various experimental conditions. As medium perfusate influences oxygenation conditions, coronary vascular response and myocardial consumption performance may differ between isolated hearts perfused with from with K...

journal_title：European journal of anaesthesiology

authors： Mouren S,Vicaut E,Lamhaut L,Riou B,Ouattara A

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Unilateral spinal anaesthesia is a useful anaesthesia technique in lower abdominal surgery, especially in an outpatient setting. Patient posture is pivotal in the achievement of unilateral anaesthesia. Nevertheless, no studies have elucidated the influence of patient posture during the anaesthe...

journal_title：European journal of anaesthesiology

authors： Al Malyan M,Becchi C,Falsini S,Lorenzi P,Boddi V,Marsili M,Boncinelli S

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Propofol is an anaesthetic that resembles α-tocopherol and it has been suggested that it protects against ischaemia-reperfusion injury in liver transplantation. Living-donor liver transplantation (LDLT) presents an opportunity to test this hypothesis in both donors and recipients. OBJECTIVES:We compared cli...

journal_title：European journal of anaesthesiology

authors： Shin S,Joo DJ,Kim MS,Bae MI,Heo E,Lee JS,Kim DW,Yoo YC

更新日期：2019-09-01 00:00:00

abstract：:Malignant hyperthermia is an autosomal-dominant inherited disorder of the skeletal muscle cell characterized by a hypermetabolic response to all commonly used inhalational anaesthetics and depolarizing muscle relaxants. The clinical syndrome includes muscle rigidity, hypercapnia, tachycardia and myoglobinuria as resul...

journal_title：European journal of anaesthesiology

authors： Wappler F

更新日期：2001-10-01 00:00:00

abstract：:A 36-year-old female presented with seizures and transient dysphasia in her 31 week of pregnancy. Neuroradiological investigations revealed a large falx meningioma. A decision was taken to deliver the infant and excise the tumor before term because of the risk of an increase in the size of the tumour and the risk of s...

journal_title：European journal of anaesthesiology

authors： Ismail K,Coakham HB,Walters FJ

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To evaluate the efficacy of 0.1% ropivacaine with fentanyl 2 microg mL(-1) via epidural for analgesia in labour. METHODS:In a randomized study, 80 nulliparous parturients in labour had epidural analgesia initiated with 0.2% ropivacaine and fentanyl and were then randomized to receive either 0....

journal_title：European journal of anaesthesiology

authors： Atienzar MC,Palanca JM,Borras R,Esteve I,Fernandez M,Miranda A

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Volatile anaesthetics inhibit nicotinic acetylcholine receptors at clinically relevant concentrations with higher affinity for the neuronal nicotinic receptor. The inhibitory effects of propofol on nicotinic receptors have only been documented at supraclinical concentrations. The aim of this st...

journal_title：European journal of anaesthesiology

authors： Barrio J,SanMiguel G,Asensio I,Molina I,López F,García V

更新日期：2005-04-01 00:00:00

abstract：:Optimal control of long-term sedation during therapy in the intensive care unit is difficult to achieve in a number of patients when based on commonly used clinical sedation scores alone. We therefore used the median frequency of the EEG power spectrum as a quantitative measure for closed-loop administration of propof...

journal_title：European journal of anaesthesiology

authors： Albrecht S,Frenkel C,Ihmsen H,Schüttler J

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Lidocaine has actions potentially of benefit during ischaemia-reperfusion. Neutrophils and endothelial cells have an important role in ischaemia-reperfusion injury. METHODS:Isolated human neutrophil CD11b and CD18, and human umbilical vein endothelial cell (HUVEC) ICAM-1 expression and supernatant IL-1beta ...

journal_title：European journal of anaesthesiology

authors： Lan W,Harmon D,Wang JH,Shorten G,Redmond P

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Magnesium sulphate is an important adjuvant drug in multimodal anaesthesia. In combination with rocuronium it can enhance neuromuscular blockade (NMB). Limited data exist concerning the effect of magnesium sulphate on the duration of deep or intense NMB and the period of no response. OBJECTIVE(S):To determi...

journal_title：European journal of anaesthesiology

authors： Queiroz Rangel Micuci AJ,Verçosa N,Filho PAG,de Boer HD,Barbosa DD,Cavalcanti IL

更新日期：2019-07-01 00:00:00

abstract：:Morbidly obese patients present with excess fatty tissue externally on the breast, neck, thoracic wall and abdomen and internally in the mouth, pharynx and abdomen. This excess tissue tends to make access (intubation, tracheostomy) to and patency (during sedation or mask ventilation) of the upper airway and the functi...

journal_title：European journal of anaesthesiology

authors： Kristensen MS

更新日期：2010-11-01 00:00:00

abstract：:Regional anaesthesia for abdominal hysterectomy is commonly combined with heavy sedation or light general anaesthesia in order to avoid the occurrence of visceral pain. Our clinical experience has indicated that this pain can be controlled using regional anaesthesia techniques alone. In an effort to find the optimal t...

journal_title：European journal of anaesthesiology

authors： Mihic DN,Abram SE

更新日期：1993-07-01 00:00:00

abstract：CONTEXT:We hypothesised that the Blind Intubation Device (BID) would be effective for nasotracheal intubation (NTI) in anaesthetised adults with Mallampati class 3. We also hypothesised that BID may cause less haemodynamic changes due to the avoidance of direct stimulation induced by the Macintosh blade. OBJECTIVE:The...

journal_title：European journal of anaesthesiology

authors： Sun Y,Liu JX,Zhu YS,Xu H,Huang Y,Jiang H

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Ultrasound guidance improves the efficacy of peripheral nerve blocks, reducing performance time and local anaesthetic doses. It should also reduce the risk of systemic toxicity of local anaesthetic and nerve injuries. OBJECTIVE:The primary objective of this prospective study was to estimate the incidence of...

journal_title：European journal of anaesthesiology

authors： Ecoffey C,Oger E,Marchand-Maillet F,Cimino Y,Rannou JJ,Beloeil H,SOS French Regional Anaesthesia Hotline.

更新日期：2014-11-01 00:00:00