The effect of anaesthetics on the myocardium--new insights into myocardial protection.

abstract：BACKGROUND AND OBJECTIVE:Bleeding after cardiac surgery correlates with morbidity and mortality. The aim of this study was to determine the influence of antiplatelet therapy on bleeding and transfusion rates in coronary artery bypass grafting. METHODS:Forty patients receiving aspirin and/or clopidogrel/ticlopidine wit...

journal_title：European journal of anaesthesiology

authors： Picker SM,Kaleta T,Hekmat K,Kampe S,Gathof BS

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Postoperative shoulder pain remains a significant problem after laparoscopy. Pneumoperitoneum with insufflation of carbon dioxide (CO2) is thought to be the most important cause. Reduction of pneumoperitoneum pressure may, however, compromise surgical visualisation. Recent studies indicate that the use of de...

journal_title：European journal of anaesthesiology

authors： Madsen MV,Istre O,Staehr-Rye AK,Springborg HH,Rosenberg J,Lund J,Gätke MR

更新日期：2016-05-01 00:00:00

abstract：:The occurrence of myocardial ischaemia will result in either reversible or irreversible myocardial dysfunction. Even when revascularization is successful, some reperfusion injury may occur that transiently impairs myocardial function. Therefore, treatment should not only be directed towards prompt restoration of myoca...

journal_title：European journal of anaesthesiology

authors： De Hert SG,Preckel B,Hollmann MW,Schlack WS

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The aim of study was to investigate the electron microscopic changes in the medulla of the spinal cord that occur with intrathecal midazolam administration. METHODS:Twenty-eight albino rabbits of New Zealand type were randomized into two groups. Following anaesthesia, 16 rabbits were given 300...

journal_title：European journal of anaesthesiology

authors： Ugur B,Basaloglu K,Yurtseven T,Ates U,Aydin ON,Ozenç D,Yurtseven M,Gürel A

更新日期：2005-12-01 00:00:00

abstract：:This randomized double blind study investigates the relative efficacies of controlled analgesia (PCA) regimens in three different patient groups: epidural diamorphine 2.5 mg followed by PCA bolus 1 mg with a 20-min lockout (Gp1), subcutaneous diamorphine 2.5 mg followed by PCA bolus with a 10-min lockout period (Gp2) ...

journal_title：European journal of anaesthesiology

authors： Gopinathan C,Sockalingham I,Fung MA,Peat S,Hanna MH

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Near-infrared spectroscopy estimates cerebral regional tissue oxygen saturation (rSO2), which may decrease under hyperventilation. Propofol and sevoflurane act differently on cerebral blood vessels. Consequently, cerebral blood flow during hyperventilation with propofol and sevoflurane anaesthesia may differ...

journal_title：European journal of anaesthesiology

authors： Ishiyama T,Kotoda M,Asano N,Ikemoto K,Shintani N,Matsuoka T,Matsukawa T

更新日期：2016-12-01 00:00:00

abstract：:There is disagreement concerning the role of nitric oxide (NO) in general anaesthesia. The present study was conducted to determine whether the anaesthetic drug isoflurane alters levels of NO metabolites, NOx (NO2 and NO3), in the hippocampus of rats during and after anaesthesia. Results showed resting hippocampal NOx...

journal_title：European journal of anaesthesiology

authors： Matsuoka H,Watanabe Y,Isshiki A,Quock RM

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Intrathecal ketamine produces a short period of analgesia with stable haemodynamics. Midazolam with bupivacaine prolongs the duration of analgesia when administered intrathecally but does not prevent hypotension. The objective of this study was to assess the effect of a combination of intrathecal bupivacaine...

journal_title：European journal of anaesthesiology

authors： Murali Krishna T,Panda NB,Batra YK,Rajeev S

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:The objective of this study was to determine the intracranial, cardiovascular and respiratory changes induced by conversion to high-frequency oscillator ventilation from conventional mechanical ventilation at increasing airway pressures. METHODS:In this study, 11 anaesthetized sheep had invasive cardiovascu...

journal_title：European journal of anaesthesiology

authors： O'Rourke J,Sheeran P,Heaney M,Talbot R,Geraghty M,Costello J,McDonnell C,Newell J,Mannion D

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The study compared the analgesic efficacy and safety of two preoperatively administered cyclo-oxygenase-2 inhibitors, celecoxib and rofecoxib. METHODS:Ninety adult patients undergoing thyroid surgery were divided into three groups (each n = 30). They were given a single oral dose of placebo, c...

journal_title：European journal of anaesthesiology

authors： Karamanlioğlu B,Arar C,Alagöl A,Colak A,Gemlik I,Süt N

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:The isolated heart model is widely used for the assessment of coronary vascular response under various experimental conditions. As medium perfusate influences oxygenation conditions, coronary vascular response and myocardial consumption performance may differ between isolated hearts perfused with from with K...

journal_title：European journal of anaesthesiology

authors： Mouren S,Vicaut E,Lamhaut L,Riou B,Ouattara A

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Proinflammatory cytokines as well as nitric oxide (NO) play a major role in mediating the response to lipopolysaccharide (LPS). The present study tested the hypothesis that LPS induces proinflammatory cytokines in the lung via the Toll-like receptor 4 (TLR4)/CD14 signalling cascade. METHODS:Co...

journal_title：European journal of anaesthesiology

authors： Baumgarten G,Knuefermann P,Wrigge H,Putensen C,Stapel H,Fink K,Meyer R,Hoeft A,Grohé C

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Alpha-2 agonists offer useful effects that make these drugs an interesting alternative for pharmacological premedication. METHODS:In a randomized, double-blind study, effects of clonidine (150 microg orally), midazolam (7.5 mg orally) and placebo administered 60-90 min prior to estimated anae...

journal_title：European journal of anaesthesiology

authors： Paris A,Kaufmann M,Tonner PH,Renz P,Lemke T,Ledowski T,Scholz J,Bein B

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Sedation is commonly used to facilitate diagnostic procedures in children. The aim of our study was to investigate sedation in children using propofol alone or combined with fentanyl or midazolam with regard to efficacy, adverse reactions or side-effects related to the drugs, ease of operation ...

journal_title：European journal of anaesthesiology

authors： Disma N,Astuto M,Rizzo G,Rosano G,Naso P,Aprile G,Bonanno G,Russo A

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The effects of altering the concentration of a local anaesthetic on the development of epidural anaesthesia in pregnant females are unclear. We compared the anaesthetic effects of a constant dose of two different concentrations of epidural lidocaine for Caesarean section. METHODS:After Institu...

journal_title：European journal of anaesthesiology

authors： Nakayama M,Yamamoto J,Ichinose H,Yamamoto S,Kanaya N,Namiki A

更新日期：2002-11-01 00:00:00

abstract：:Cardiovascular and hormonal responses to reconstructive abdominal aortic surgery were studied in 20 patients anaesthetized either with moderate-dose fentanyl (20 micrograms kg-1) combined with isoflurane, nitrous oxide and oxygen (n = 10), or with thoracolumbar epidural bupivacaine combined with isoflurane, nitrous ox...

journal_title：European journal of anaesthesiology

authors： Kataja J

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:Control of blood pressure remains a key goal of peri-operative care, because hypotension is associated with adverse outcomes after surgery. OBJECTIVES:We explored whether increased vigilance afforded by intra-arterial blood pressure monitoring may be associated with less morbidity after surgery. DESIGN:A p...

journal_title：European journal of anaesthesiology

authors： Abbott TEF,Howell S,Pearse RM,Ackland GL,VISION-UK Investigators.

更新日期：2021-01-12 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Unilateral paravertebral nerve blockade has been reported to produce excellent afferent nerve block, reduce the incidence of postoperative nausea and vomiting, and reduce hospital stay following inguinal hernia repair. The aim was to compare the use of bilateral paravertebral blocks to regular ...

journal_title：European journal of anaesthesiology

authors： Naja Z,Ziade MF,Lönnqvist PA

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Isoflurane has been shown experimentally to protect the myocardium against infarction but the clinical relevance of these findings is not yet well established. We therefore evaluated the effects of isoflurane administration before cardiopulmonary bypass (CPB) on postoperative cardiac troponin I...

journal_title：European journal of anaesthesiology

authors： Fellahi JL,Gue X,Philippe E,Riou B,Gerard JL

更新日期：2004-09-01 00:00:00

abstract：:The rate of failed spinal anaesthesia, defined as the need for unplanned general anaesthesia, was evaluated in a prospective study involving 137 patients undergoing transurethral resection of the prostate (TURP). The incidence of sensations at the operative site which did not require general anaesthesia was also evalu...

journal_title：European journal of anaesthesiology

authors： Guinard JP,Carpenter RL,Smith HS

更新日期：1992-01-01 00:00:00

abstract：:The suitability of tramadol suppositories for inclusion in our hospital formulary for the treatment of mild to moderate post-operative pain was evaluated. In an open randomized trial, rectal tramadol was compared with our standard treatment acetaminophen/codeine suppositories. We expected tramadol to be equally effect...

journal_title：European journal of anaesthesiology

authors： Pluim MA,Wegener JT,Rupreht J,Vulto AG

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The aim of the present study was to determine the dosage of remifentanil that must be added to thiopental 5 mg kg(-1) to provide excellent intubating conditions in 95% of patients. METHODS:Sixty-eight premedicated female American Society of Anesthesiologists class 1 and 2 patients were randoml...

journal_title：European journal of anaesthesiology

authors： Bouvet L,Stoian A,Rousson D,Allaouchiche B,Chassard D,Boselli E

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:We compared the effects of sub-Tenon's local anaesthetic block and placebo on peri-operative opioid requirement and cardiovascular stability and on postoperative pain, nausea and vomiting in patients undergoing vitreo-retinal surgery under general anaesthesia. METHODS:We studied 43 patients un...

journal_title：European journal of anaesthesiology

authors： Farmery AD,Shlugman D,Rahman R,Rosen P

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:Magnesium sulphate is an important adjuvant drug in multimodal anaesthesia. In combination with rocuronium it can enhance neuromuscular blockade (NMB). Limited data exist concerning the effect of magnesium sulphate on the duration of deep or intense NMB and the period of no response. OBJECTIVE(S):To determi...

journal_title：European journal of anaesthesiology

authors： Queiroz Rangel Micuci AJ,Verçosa N,Filho PAG,de Boer HD,Barbosa DD,Cavalcanti IL

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Intravenous administration of compound sodium lactate (CSL) 30 ml kg to women undergoing gynaecological laparoscopy reduced the incidence of vomiting, nausea and antiemetic use when compared with 10 ml kg. The aim of this study was to evaluate the effect of intravenous fluid administration on n...

journal_title：European journal of anaesthesiology

authors： Dagher CF,Abboud B,Richa F,Abouzeid H,El-Khoury C,Doumit C,Yaghi C,Yazbeck P

更新日期：2009-03-01 00:00:00

abstract：CONTEXT:Perioperative oral carbohydrate intake is beneficial to general surgery patients. Total hip arthroplasty is a common surgical procedure, and even a moderate improvement in patient outcome could have a significant effect on the resources needed for these patients. However, few studies have focused on the effects...

journal_title：European journal of anaesthesiology

authors： Harsten A,Hjartarson H,Toksvig-Larsen S

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Hyperlactataemia represents oxygen imbalance in the tissues and its occurrence during cardiac surgery is associated with adverse outcomes. Glucose-insulin-potassium (GIK) infusion confers myocardial protection against ischaemia-reperfusion injury and has the potential to reduce lactate release while improvin...

journal_title：European journal of anaesthesiology

authors： Roh GU,Shim JK,Song JW,Kang HM,Kwak YL

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Most therapeutic options for postoperative delirium are only symptom oriented; therefore, the best approach remains prevention. The aim of this study was to identify predisposing and precipitating factors for early postoperative delirium. METHODS:A total of 1002 patients were screened for deli...

journal_title：European journal of anaesthesiology

authors： Radtke FM,Franck M,MacGuill M,Seeling M,Lütz A,Westhoff S,Neumann U,Wernecke KD,Spies CD

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:ProSeal Laryngeal Mask Airway (PLMA) and Laryngeal Tube Suction (LTS), supraglottic airway devices allowing gastric drainage, were compared in this prospective, randomized study for airway management under conditions with elevated intra-abdominal pressure induced by capnoperitoneum. METHODS:Fi...

journal_title：European journal of anaesthesiology

authors： Roth H,Genzwuerker HV,Rothhaas A,Finteis T,Schmeck J

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The importance of monitoring the breathing pattern during sedation of children undergoing magnetic resonance scans is indicated in guidelines, but no appropriate magnetic resonance-compatible devices are available. We report preliminary findings from a technique referred to as remote pressure s...

journal_title：European journal of anaesthesiology

authors： Caldiroli D,Minati L

更新日期：2007-09-01 00:00:00