Effects of clonidine and midazolam premedication on bispectral index and recovery after elective surgery.

abstract：BACKGROUND AND OBJECTIVE:Statins are prescribed for patients with hypercholesterolemia. Atorvastatin is metabolized by cytochrome P4503A4 and inhibits P4503A4 activity in vitro. Alfentanil is a potent opioid used in clinical anaesthetic practice and is also metabolized by P4503A4. This study tested the hypothesis that ...

journal_title：European journal of anaesthesiology

authors： McDonnell CG,Malkan D,Van Pelt FD,Shorten GD

更新日期：2003-08-01 00:00:00

abstract：:Diazepam premedication decreases the overall metabolic rate and oxygen consumption. Whether its properties are shared by midazolam is not known. In this study, eight healthy male volunteers were given oral diazepam (10 mg), midazolam (15 mg) and placebo in a random double-blind cross-over fashion. Metabolic responses ...

journal_title：European journal of anaesthesiology

authors： Kirvelä O,Katila A,Aantaa R,Kanto J,Himberg JJ

更新日期：1994-09-01 00:00:00

abstract：CONTEXT:The single-use Laryngeal Mask Airway (LMA) Supreme is a new supraglottic airway device. It has been reported to be reliable and easy-to-use in clinical practice; however, the anaesthetic techniques for its insertion are not standardised. OBJECTIVES:The purpose of this study was to determine the ED50 of end-tid...

journal_title：European journal of anaesthesiology

authors： Zaballos M,Bastida E,Jiménez C,Agustí S,López-Gil MT

更新日期：2013-04-01 00:00:00

abstract：:We studied the movement response to skin incision in 68 adult (males/females) ASA I-II patients receiving propofol +/- fentanyl intravenous anaesthesia using the bispectral index and 95% spectral edge frequency monitoring with an A-1050 EEG monitor. Following Ethics Committee approval, patients were randomly assigned ...

journal_title：European journal of anaesthesiology

authors： Singh H,Sakai T,Matsuki A

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The elderly represent a wide and increasing patient population and significant numbers of elderly patients have chronic renal disease. This study aimed to investigate the neuromuscular effects of 0.6 mg kg(-1) rocuronium under propofol anaesthesia in young adults and elderly patients with or w...

journal_title：European journal of anaesthesiology

authors： Kocabas S,Yedicocuklu D,Askar FZ

更新日期：2008-11-01 00:00:00

abstract：:The analgesic efficacy of tenoxicam, a newer injectable non-steroidal anti-inflammatory drug, for post-operative analgesia after abdominal or orthopaedic surgery in ASA Grade I/II patients is reported. Two hundred and fifty-six patients received a single dose of tenoxicam 40 mg intravenous (i.v.) at the end of surgery...

journal_title：European journal of anaesthesiology

authors： Vandermeulen EP,Van Aken H,Scholtes JL,Singelyn F,Buelens A,Haazen L

更新日期：1997-05-01 00:00:00

abstract：INTRODUCTION:We tested the hypothesis that repeated autoclaving removes protein deposits from the classic laryngeal mask airway (LMA). METHODS:Twenty previously used LMAs were hand washed, machine washed, dried, autoclaved and randomly allocated into four equal-sized groups for repeat autoclaving on 0 (control), 1, 2 ...

journal_title：European journal of anaesthesiology

authors： Bannon L,Brimacombe J,Nixon T,Keller C

更新日期：2005-07-01 00:00:00

abstract：:The effects of 5% and 8% glucose in 0.5% tetracaine or bupivacaine on the anaesthetic spread were investigated in 80 urological patients requiring spinal anaesthesia for trans-urethral resection of the prostate. The local anaesthetic solutions were randomly administered, the patients being divided into four groups of ...

journal_title：European journal of anaesthesiology

authors： Janik R,Dick W,Stanton-Hicks MD

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:When continuous infusions of neuromuscular blocking drugs are administered during lengthy interventions and no routine antagonism of their effects is applied, there is a dramatic incidence of residual curarization. We have examined whether the use of neuromuscular transmission monitoring result...

journal_title：European journal of anaesthesiology

authors： Cammu G,De Keersmaecker K,Casselman F,Coddens J,Hendrickx J,Van Praet E,Deloof T

更新日期：2003-11-01 00:00:00

abstract：:We studied whether long-term epidural catheter (nylon) placement for bupivacaine administration (morphine in 2 pigs) would cause any pathological changes in the epidural space and spinal cord of pigs. There were similar kinds of slight inflammatory changes in ligamentum flavum and dura mater in bupivacaine-treated (4 ...

journal_title：European journal of anaesthesiology

authors： Kyttä J,Rosenberg PH,Wahlström TR

更新日期：1986-11-01 00:00:00

abstract：:In this review paper, the authors critically analyse the use of a number of depth of anaesthesia monitors in light of the most recent literature and their own clinical experience. There appears to be increasing evidence that anaesthesia depth monitors reduce the incidence of unexpected intraoperative awareness and als...

journal_title：European journal of anaesthesiology

authors： Bonhomme V,Hans P

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Robot-assisted prostatectomy requires pneumoperitoneum in a steep Trendelenburg position, which may induce endobronchial intubation or accidental extubation. The aim of the study was to evaluate the effect of pneumoperitoneum in 30 degrees Trendelenburg position on the displacement of the trach...

journal_title：European journal of anaesthesiology

authors： Chang CH,Lee HK,Nam SH

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Arterial pressure waveform analysis enables continuous, minimally invasive measurement of cardiac output. Haemodynamic instability compromises the reliability of the technique and a means of maintaining accurate measurement in this circumstance would be useful. OBJECTIVES:To investigate the accuracy, precis...

journal_title：European journal of anaesthesiology

authors： Montenij LJ,Buhre WF,de Jong SA,Harms JH,van Herwaarden JA,Kruitwagen CL,de Waal EE

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To compare the inotropic and lusitropic effect of lidocaine and mepivacaine on rat papillary muscle. METHODS:Effects of lidocaine and mepivacaine (10-8-10-3 M) were studied in rat left ventricular papillary muscles in vitro at a calcium concentration of 1 mmol, under low (isotony) and high (is...

journal_title：European journal of anaesthesiology

authors： David JS,Amour J,Duracher C,Ferretti C,Precloux P,Petit P,Riou B,Gueugniaud PY

更新日期：2007-02-01 00:00:00

abstract：CONTEXT:Perioperative oral carbohydrate intake is beneficial to general surgery patients. Total hip arthroplasty is a common surgical procedure, and even a moderate improvement in patient outcome could have a significant effect on the resources needed for these patients. However, few studies have focused on the effects...

journal_title：European journal of anaesthesiology

authors： Harsten A,Hjartarson H,Toksvig-Larsen S

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Previous studies have shown that general anaesthetic agents modulate the production of hypothalamic prostaglandins (PG) D2 and E2, which are mediators of sleep and wakefulness respectively. Although flurbiprofen, a cyclo-oxygenase inhibitor, is used clinically as a non-steroidal anti-inflammato...

journal_title：European journal of anaesthesiology

authors： Hirota K,Fukushi S,Baba S,Matsuki A

更新日期：2002-07-01 00:00:00

abstract：CONTEXT:Strabismus surgery is one of the most common ophthalmic surgical procedures in children and is associated with significant postoperative nausea and vomiting (PONV). OBJECTIVE:We evaluated the effect of intravenous paracetamol on PONV in children after strabismus surgery. DESIGN:Prospective, placebo-controlled...

journal_title：European journal of anaesthesiology

authors： Cok OY,Eker HE,Pelit A,Canturk S,Akin S,Aribogan A,Arslan G

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:We explored the effects of morphine administration during reperfusion period after an index ischaemia as well as potential molecular mechanisms underlying this response. This is of important clinical value, as morphine is used routinely in cardiovascular anaesthesia and in the emergency manage...

journal_title：European journal of anaesthesiology

authors： Mourouzis I,Saranteas T,Perimenis P,Tesseromatis C,Kostopanagiotou G,Pantos C,Cokkinos DV

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:In patients undergoing general anaesthesia, intraoperative hypotension occurs frequently and is associated with adverse outcomes such as postoperative acute kidney failure, myocardial infarction or stroke. A history of chronic hypertension renders patients more susceptible to a decrease in blood pressure (BP...

journal_title：European journal of anaesthesiology

authors： Meidert AS,Nold JS,Hornung R,Paulus AC,Zwißler B,Czerner S

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The glutamate-nitric oxide-cyclic guanosine monophosphate pathway has been identified as a potential target for anaesthetic agents. However, mice deficient in neuronal nitric oxide synthase have a similar susceptibility to volatile anaesthetic agents to wild-type mice and are not affected by no...

journal_title：European journal of anaesthesiology

authors： Engelhardt T,Lowe PR,Galley HF,Webster NR

更新日期：2006-03-01 00:00:00

abstract：:The occurrence of myocardial ischaemia will result in either reversible or irreversible myocardial dysfunction. Even when revascularization is successful, some reperfusion injury may occur that transiently impairs myocardial function. Therefore, treatment should not only be directed towards prompt restoration of myoca...

journal_title：European journal of anaesthesiology

authors： De Hert SG,Preckel B,Hollmann MW,Schlack WS

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Use of dipyrone (metamizole) in perioperative and ICU pain therapy remains controversial due to a lack of solid evidence weighing dipyrone benefit against its potential life-threatening complications. Although dipyrone has known analgesic and antipyretic properties, its mechanisms of actions are incompletely...

journal_title：European journal of anaesthesiology

authors： Stueber T,Buessecker L,Leffler A,Gillmann HJ

更新日期：2017-10-01 00:00:00

abstract：:The effect of the administration of a 50 mg dose of an angiotensin converting enzyme inhibitor (captopril) on the mean arterial pressure following sternotomy in 13 patients undergoing coronary artery bypass surgery was indistinguishable from the response in 13 patients who had not received the drug. ...

journal_title：European journal of anaesthesiology

authors： Cashman JN,Jones RM,Thompson MA

更新日期：1984-09-01 00:00:00

abstract：:Simulation is often used for training personnel in activities where the consequences of inappropriate actions are serious. We report a realistic training simulator, which can reproduce practically all potential malfunctions in the anaesthetic machine. Using actual standard equipment (Dameca 10750), the interior of the...

journal_title：European journal of anaesthesiology

authors： Berge JA,Gramstad L,Jensen O

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Neostigmine is widely used to antagonise residual paralysis. Over the last decades, the benchmark of acceptable neuromuscular recovery has increased progressively to a train-of-four (TOF) ratio of at least 0.9. Raising this benchmark may impact on the efficacy of neostigmine. OBJECTIVE(S):The systematic rev...

journal_title：European journal of anaesthesiology

authors： Tajaate N,Schreiber JU,Fuchs-Buder T,Jelting Y,Kranke P

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Administration of calcium safely and effectively reverses many of the electrophysiological actions of hyperkalaemia, but it has not been studied for pretreatment. Based on cellular studies, magnesium also has been suggested to prevent the effects of potassium on the heart. As their mechanisms o...

journal_title：European journal of anaesthesiology

authors： Hollmann MW,Strümper D,Salmons VA,Washington JM,Durieux ME

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:The base excess gap (BE(gap)) method is commonly used for the quantification of unmeasured ions in critically ill patients. However, it has never been validated against the standard quantitative acid-base approach. OBJECTIVE:To compare the BE(gap) as a tool for the prediction of the excess of unmeasured ion...

journal_title：European journal of anaesthesiology

authors： Agrafiotis M,Sileli M,Ampatzidou F,Keklikoglou I,Panousis P

更新日期：2013-11-01 00:00:00

abstract：:A 36-year-old female presented with seizures and transient dysphasia in her 31 week of pregnancy. Neuroradiological investigations revealed a large falx meningioma. A decision was taken to deliver the infant and excise the tumor before term because of the risk of an increase in the size of the tumour and the risk of s...

journal_title：European journal of anaesthesiology

authors： Ismail K,Coakham HB,Walters FJ

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To evaluate the noninvasive electrical velocimetry (Aesculon) monitor for cardiac output (CO) by subxiphoidal Doppler flow measurement in children. METHODS:CO was determined at the end of diagnostic or interventional cardiac catheterization for congenital heart defects. Standard ECG surface el...

journal_title：European journal of anaesthesiology

authors： Tomaske M,Knirsch W,Kretschmar O,Balmer C,Woitzek K,Schmitz A,Bauersfeld U,Weiss M,Working Group on Noninvasive Haemodynamic Monitoring in Paediatrics.

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The effects of altering the concentration of a local anaesthetic on the development of epidural anaesthesia in pregnant females are unclear. We compared the anaesthetic effects of a constant dose of two different concentrations of epidural lidocaine for Caesarean section. METHODS:After Institu...

journal_title：European journal of anaesthesiology

authors： Nakayama M,Yamamoto J,Ichinose H,Yamamoto S,Kanaya N,Namiki A

更新日期：2002-11-01 00:00:00