Drugs mediating myocardial protection.

Abstract:

:The occurrence of myocardial ischaemia will result in either reversible or irreversible myocardial dysfunction. Even when revascularization is successful, some reperfusion injury may occur that transiently impairs myocardial function. Therefore, treatment should not only be directed towards prompt restoration of myocardial blood flow but measures should also be taken to prevent or alleviate the consequences of myocardial reperfusion injury. Over the years, various strategies have been developed. The present contribution reviews a number of these strategies focusing on pharmacological treatments that have been developed to address myocardial reperfusion injury.

journal_name

Eur J Anaesthesiol

authors

De Hert SG,Preckel B,Hollmann MW,Schlack WS

doi

10.1097/EJA.0b013e32832fad8b

subject

Has Abstract

pub_date

2009-12-01 00:00:00

pages

985-95

issue

12

eissn

0265-0215

issn

1365-2346

journal_volume

26

pub_type

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