Classical swine H1N1 influenza viruses confer cross protection from swine-origin 2009 pandemic H1N1 influenza virus infection in mice and ferrets.

abstract：:Of five globally important VP7 (G) serotypes (G1-4 and 9) of group A rotaviruses (the single most important etiologic agents of infantile diarrhea worldwide), G9 continues to attract considerable attention because of its unique natural history. Serotype G9 rotavirus was isolated from a child with diarrhea first in the...

journal_title：Virology

authors： Hoshino Y,Honma S,Jones RW,Ross J,Santos N,Gentsch JR,Kapikian AZ,Hesse RA

更新日期：2005-02-05 00:00:00

abstract：:Influenza A virus, a respiratory pathogen manipulates various host cellular processes to establish a successful infection in a host. We had reported earlier the interaction of influenza A virus nucleoprotein with host glycolytic enzymes; alpha enolase and pyruvate kinase in A549 cells. Matrix protein (M1), another mul...

journal_title：Virology

authors： Mishra S,Goyal P,Kumar D,Chaudhari R,Rajala MS

更新日期：2020-10-01 00:00:00

abstract：:Enveloped virus entry occurs when viral and cellular membranes fuse releasing particle contents into the target cell. Human immunodeficiency virus (HIV) entry occurs by cell-free virus or virus transferred between infected and uninfected cells through structures called virological synapses. We developed a high-through...

journal_title：Virology

authors： Esposito AM,Cheung P,Swartz TH,Li H,Tsibane T,Durham ND,Basler CF,Felsenfeld DP,Chen BK

更新日期：2016-03-01 00:00:00

abstract：:The sequences of the 3'-noncoding regions (NCR) of 12 strains of tick-borne encephalitis (TBE) virus were analyzed and found to vary in length from 350 to approximately 750 nucleotides. The size heterogeneity is restricted to a variable region following the stop codon, whereas the most 3'-terminal 350 nucleotides form...

journal_title：Virology

authors： Wallner G,Mandl CW,Kunz C,Heinz FX

更新日期：1995-10-20 00:00:00

abstract：:HIV-1 transmission is usually initiated by a single viral strain called transmitted/ founder (T/F) virus. In in vitro models, HIV-1 can efficiently spread via cell-free and virological synapse (VS)-mediated cell-to-cell infection. Both modes of infection require the viral glycoprotein Envelope (Env). The efficiency wi...

journal_title：Virology

authors： Li H,Chen BK

更新日期：2019-01-02 00:00:00

abstract：:A series of CD8(+) T cell clones, specific for the IE1 epitope YPHFMPTNL, of the immediate-early protein 1 of the murine cytomegalovirus (MCMV) were generated in order to determine their protective activity against this infection and correlate their phenotypic markers with antiviral activity. We found that the adoptiv...

journal_title：Virology

authors： Fernandez JA,Zavala F,Tsuji M

更新日期：1999-03-01 00:00:00

abstract：:TMV capsid protein reacts with and encapsidates many of the chloroplast DNA transcripts both in vivo and in vitro to form pseudovirions. We report on the encapsidation initiation reaction with one of the major RNA species found in in vivo formed pseudovirions, the mRNA for the chloroplast-encoded large subunit of ribu...

journal_title：Virology

authors： Atreya CD,Siegel A

更新日期：1989-02-01 00:00:00

abstract：:The bovine papilloma virus (BPV) E1 protein essential to viral DNA replication has recently been shown to associate via direct protein-DNA interactions with the viral origin of replication and to be an ATP-dependent helicase. We show here that in accordance with the latter function, the E1 gene product has intrinsic A...

journal_title：Virology

authors： MacPherson P,Thorner L,Parker LM,Botchan M

更新日期：1994-10-01 00:00:00

abstract：:We have analyzed the limiting factors involved in the induction of human immunodeficiency virus type 1 (HIV-1) provirus expression by tumor necrosis factor-alpha (TNF-alpha), phorbol-12-myristate-13-acetate (PMA), and bryostatin-1 in T-cells (ACH-2) and monocytes (U1). We have demonstrated that, while there is a corre...

journal_title：Virology

authors： Vlach J,Pitha PM

更新日期：1992-03-01 00:00:00

abstract：:The reticuloendotheliosis virus (REV) group of retroviruses and type D simian retroviruses (SRV) belong to the same receptor interference group. The cellular receptor for these viruses has not yet been identified. In order to study the distribution of the receptor and to identify a receptor negative cell line, vector ...

journal_title：Virology

authors： Koo HM,Parthasarathi S,Ron Y,Dougherty JP

更新日期：1994-11-15 00:00:00

abstract：:Human gammaherpesvirus 8 (HHV-8) is the etiologic agent of Kaposi's sarcoma, multicentric Castleman's disease and primary effusion lymphoma. Like other herpesviruses, the HHV-8 may exhibit latent or lytic cycle, both regulated by viral and host factors. Regarding host factors, we analysed the association of polymorphi...

journal_title：Virology

authors： Gonçales JP,Silva Júnior JVJ,Lopes TRR,Tozetto-Mendoza TR,de Farias Guimarães D,de Morais VMS,Coêlho MRCD

更新日期：2019-09-01 00:00:00

abstract：:Autographa californica multiple nucleopolyhedrovirus (AcMNPV) encodes two proteins that possess properties typical of single-stranded DNA-binding proteins (SSBs), late expression factor-3 (LEF-3), and a protein referred to as DNA-binding protein (DBP). Whereas LEF-3 is a multi-functional protein essential for viral DN...

journal_title：Virology

authors： Vanarsdall AL,Mikhailov VS,Rohrmann GF

更新日期：2007-08-01 00:00:00

abstract：:Marek's disease virus (MDV) is an oncogenic alphaherpesvirus of Gallus gallus, the domesticated chicken. Control strategies rely upon vaccination with live attenuated viruses of antigenically similar avian herpesviruses or attenuated strains of MDV. Recent studies in other viruses have shown that recoding certain vira...

journal_title：Virology

authors： Conrad SJ,Silva RF,Hearn CJ,Climans M,Dunn JR

更新日期：2018-03-01 00:00:00

abstract：:Turnip crinkle virus (TCV) (family Tombusviridae, genus Carmovirus) is a positive-sense RNA virus containing a 4054-base genome. Previous results indicated that insertion of Hairpin 4 (H4) into a TCV-associated satellite RNA enhanced replication 6-fold in vivo (Nagy, P., Pogany, J., Simon, A. E., 1999. EMBO J. 18:5653...

journal_title：Virology

authors： Sun X,Simon AE

更新日期：2006-08-15 00:00:00

abstract：:Respiratory syncytial virus (RSV) induces the production of a number of cytokines and chemokines by activation of nuclear factor kappa B (NF-kappaB). The activation of NF-kappaB has been shown to depend on viral replication in the infected cells. In this study, we demonstrate that expression of RSV M2-1 protein, a tra...

journal_title：Virology

authors： Reimers K,Buchholz K,Werchau H

更新日期：2005-01-20 00:00:00

abstract：:Certain temperature-sensitive (ts) mutants of murine leukemia virus (MuLV) were observed to be defective in virus assembly. These mutants also accumulated intracellular core protein precursor, Pr65gag, at 39 degrees, the nonpermissive temperature. At 39 degrees, virions released from cells infected with the various ts...

journal_title：Virology

authors： Edbauer CA,Naso RB

更新日期：1984-04-30 00:00:00

abstract：:Mammalian type C retroviruses can be detected by their induction of foci of cell transformation in S+I - cells. We have noted that certain subtypes of the mouse xenotropic type C retrovirus (MuLV) inhibit this cell alteration. This inhibition, associated with intact virions, is irreversible and gives the infected cell...

journal_title：Virology

authors： Hoffman AD,Levy JA

更新日期：1987-09-01 00:00:00

abstract：:The induction of autoimmunity by viruses has been hypothesized to occur by a number of mechanisms. Coxsackievirus B4 (CB4) induces hyperglycemia in SJL mice resembling diabetes in humans. While virus is effectively cleared within 2 weeks, hyperglycemia does not appear until about 8-12 weeks postinfection at a time whe...

journal_title：Virology

authors： Horwitz MS,Ilic A,Fine C,Rodriguez E,Sarvetnick N

更新日期：2003-09-30 00:00:00

abstract：:Replication of hepatitis B virus (HBV) proceeds by reverse transcription of an RNA intermediate inside the viral nucleocapsid formed by the core protein. This protein contains four Cys residues which occur at equivalent positions in the core proteins of all known mammalian hepadnaviruses, suggesting that they might be...

journal_title：Virology

authors： Nassal M

更新日期：1992-09-01 00:00:00

abstract：:Binding of interferons (IFNs) to their cell surface receptors stimulates rapid translocation of cytoplasmic proteins to the nucleus and the expression of a variety of cellular genes within minutes. Translocated proteins subsequently bind to the interferon-stimulated response element (ISRE) located in the promoters of ...

journal_title：Virology

authors： Nakagawa Y,Petricoin EF 3rd,Akai H,Grimley PM,Rupp B,Larner AC

更新日期：1992-09-01 00:00:00

abstract：:The infectivity in vivo, replication competence in vitro, and expression of viral genes of several molecularly cloned duck hepatitis B virus (DHBV) genomes were investigated. In addition, replication competence, core protein expression, and secretion of viral proteins were investigated for a grey heron hepatitis B vir...

journal_title：Virology

authors： Wildner G,Fernholz D,Sprengel R,Schneider R,Will H

更新日期：1991-11-01 00:00:00

abstract：:The vaginal and rectal mucosae are the first line of cellular immune defense to sexually transmitted human immunodeficiency virus type 1 (HIV-1) entry. Thus, intraepithelial lymphocytes (IELs) may be important in the immune response to HIV infection. Here we investigated whether functional IELs in mucosal compartments...

journal_title：Virology

authors： Stevceva L,Moniuszko M,Alvarez X,Lackner AA,Franchini G

更新日期：2004-02-20 00:00:00

abstract：:The effects of P2 prophage on lambda-mediated depression of host metabolism, and on lambda macromolecular synthesis have been studied. Experiments employing certain lambdabio deletion mutants and lambda-related phages suggest that the same gene products are involved in inhibition of host metabolism (Hin+ function) and...

journal_title：Virology

authors： Cohen SN,Chang AC

更新日期：1971-11-01 00:00:00

abstract：:Glycoprotein C (gC) of pseudorabies virus, a swine herpesvirus, initiates virus attachment by binding to heparan sulfate (HS) linked to proteoglycans (HSPGs) on the cell surface. This interaction facilitates a required step in virus entry, the binding to a non-HS coreceptor, likely by another viral glycoprotein, gD. W...

journal_title：Virology

authors： Rue CA,Ryan P

更新日期：2003-03-01 00:00:00

abstract：:We compared the levels of the Ski oncoprotein, an inhibitor of transforming growth factor-beta (TGF-β) signaling, in normal human keratinocytes (HKc), HPV16 immortalized HKc (HKc/HPV16), and differentiation resistant HKc/HPV16 (HKc/DR) in the absence and presence of TGF-β. Steady-state Ski protein levels increased in ...

journal_title：Virology

authors： Chen Y,Pirisi L,Creek KE

更新日期：2013-09-01 00:00:00

abstract：:Barley stripe mosaic virus (BSMV) has a tripartite genome comprising RNAs designated alpha, beta, and gamma, which collectively encode seven polypeptides. We show here that an antiserum raised against an abundant disease-specific protein from BSMV-infected plants reacts specifically with the viral beta b gene product ...

journal_title：Virology

authors： Petty IT,Jackson AO

更新日期：1990-08-01 00:00:00

abstract：:Deletion of the nef gene results in viral attenuation and confers protection against challenge with wild-type simian immunodeficiency virus in macaques. Regarding HIV-1 infection, a few long-term nonprogressors (LTNP) with nef deletions have been described. In this study, the nef genes of a group of seven LTNP and eig...

journal_title：Virology

authors： Brambilla A,Turchetto L,Gatti A,Bovolenta C,Veglia F,Santagostino E,Gringeri A,Clementi M,Poli G,Bagnarelli P,Vicenzi E

更新日期：1999-07-05 00:00:00

abstract：:Gp110 of Epstein-Barr virus (EBV) mainly localizes on nuclear/ER membranes and plays a role in the assembly of EBV nucleocapsid. The C-terminal tail domain (gp110 CTD) is essential for the function of gp110 and the nuclear/ER membranes localization of gp110 is ruled by its C-terminal unique nuclear localization signal...

journal_title：Virology

authors： Park SJ,Seo MD,Lee SK,Lee BJ

更新日期：2008-09-30 00:00:00

abstract：:Infectious bronchitis virus (IBV) produces six subgenomic (sg) mRNAs, each containing a 64 nucleotide (nt) leader sequence, derived from the 5' end of the genome by a discontinuous process. Several putative functional domains such as a papain-like proteinase (PL(pro)), main protease (M(pro)), RNA-dependent RNA polymer...

journal_title：Virology

authors： Mondal SP,Cardona CJ

更新日期：2004-06-20 00:00:00

abstract：:The failure of HIV-1 to escape at some cytotoxic T-lymphocyte (CTL) epitopes has generally been explained in terms of viral fitness costs or ineffective or attenuated CTL responses. Relatively little attention has been paid to the evolutionary time required for escape mutants to be detected. This time is significantly...

journal_title：Virology

authors： Liu Y,Mullins JI,Mittler JE

更新日期：2006-03-30 00:00:00