Monitoring bacterial contamination of blood components in Germany: effect of contamination reduction measures.

abstract：:A competitive inhibition assay for functional fibronectin (Fn), based on ELISA technology, is described. The assay measures Fn's physiologic ability to bind to denatured collagen (gelatin). Affinity-purified Fn inhibits the binding of alkaline phosphatase coupled Fn to gelatin-coated wells of a microtiter plate in a c...

journal_title：Vox sanguinis

authors： Doran JE,Callaway BD,Reese AC,Wynn JJ,Mansberger AR

更新日期：1983-01-01 00:00:00

abstract：:Peripheral blood stem cell cryopreservation is associated with cell damage and decreased viability. We evaluated the impact of up to 10 years of cryopreservation (5% DMSO) on viability of CD34(+) cells utilizing graft samples of consecutive patients (2002-2012) with different malignancies who underwent stem cell colle...

journal_title：Vox sanguinis

authors： Abbruzzese L,Agostini F,Durante C,Toffola RT,Rupolo M,Rossi FM,Lleshi A,Zanolin S,Michieli M,Mazzucato M

更新日期：2013-07-01 00:00:00

abstract：:The presence of the glycoproteins haptoglobin and hemopexin in human plasma albumin (HPA) solutions were demonstrated to be responsible for the formation of polymers and aggregates during heat treatment for 10 h at 60 degrees C. Apart from haptoglobin and hemopexin three other contaminating proteins were identified as...

journal_title：Vox sanguinis

authors： Jensen LB,Dam J,Teisner B

更新日期：1994-01-01 00:00:00

abstract：:A delayed hemolytic transfusion reaction (DHTR) occurring in a 30-year-old Caucasian man is described. His blood groups were B, CDe/cDE (R1R2, f-) K-, S-s+, Fy (a + b-), and Jk (a + b +). Eight days after receiving two units of packed red blood cells, his urine was strongly positive for hemoglobin; serum-free hemoglob...

journal_title：Vox sanguinis

authors： O'Reilly RA,Lombard CM,Azzi RL

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Warm autoantibodies (WAA) are antibodies that react with an antigen on a patient's own red-blood-cells and can complicate compatibility testing whether or not they cause clinical haemolysis. The goal of this study was to understand the overall prevalence of WAA, the risk of RBC alloimmunization and determine...

journal_title：Vox sanguinis

authors： Delaney M,Apelseth TO,Bonet Bub C,Cohn CS,Dunbar NM,Mauro Kutner J,Murphy M,Perelman I,Selleng K,Staves J,Wendel S,Ziman A,Biomedical Excellence for Safer Transfusion (BEST) Collaborative.

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:To prove the feasibility of a semi-automated cross-match procedure using a commercially available solid-phase microplate test and standard laboratory equipment. MATERIAL AND METHODS:The new procedure was evaluated against the conventional spin tube technique and the gel centrifugation system....

journal_title：Vox sanguinis

authors： Ostendorf N,Niefhoff D,Cassens U,Sibrowski W

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The molecular basis of the weak D phenotype has been investigated for many years, and more than 80 different alleles producing weak D phenotypes have been identified. Most alleles producing weak D phenotypes have a single missense mutation in exons corresponding to a transmembrane domain of th...

journal_title：Vox sanguinis

authors： Ogasawara K,Sasaki K,Isa K,Tsuneyama H,Uchikawa M,Satake M,Tadokoro K

更新日期：2016-02-01 00:00:00

abstract：:A pilot study for large-scale automated plasmapheresis using the Haemonetics Model 50 machine was undertaken in the Yorkshire Region of the United Kingdom to determine the viability of such a programme for national self-sufficiency in fresh plasma procurement for factor VIII concentrate production. The study was desig...

journal_title：Vox sanguinis

authors： Robinson AE,Penny AF,Smith J,Tovey DL

更新日期：1983-03-01 00:00:00

abstract：:A new competitive solid phase radioimmunoassay (CLB-RIA) has been developed for the detection of HBAg and HBAb in human serum and plasma. In the assay, sheep antibodies to HBAg, covalently linked to an insoluble carrier, highly purified 125-I labelled HBAg and the serum or plasma sample are incubated for 20 h at room ...

journal_title：Vox sanguinis

authors： Duimel WJ,Brummelhuis HG

更新日期：1975-01-01 00:00:00

abstract：:Pre- and posttransfusion antibody titers were performed on 6 patients with anti-Sda transfused with incompatible blood. In 3 of these patients a significant rise in IgG antibody titer was found. The data suggest that in occasional patients the Sda antigen does evoke a secondary immune response. We evaluated 245 pregna...

journal_title：Vox sanguinis

authors： Spitalnik S,Cox MT,Spennacchio J,Guenther R,Blumberg N

更新日期：1982-01-01 00:00:00

abstract：:Employing standardized IgG-coated 51Cr-labelled human red blood cells (RBC), variation in rosette formation among monolayers obtained from 10 healthy donors was defined, as well as variation among 24 sequential monolayers obtained from one healthy donor and 8 sequential monolayers from a second healthy donor over a 4-...

journal_title：Vox sanguinis

authors： Munn LR,Chaplin H Jr

更新日期：1977-09-01 00:00:00

abstract：:63 Rh-negative male volunteers were immunized with D-positive red cells. 28 (44%) produced anti-D. To provide sustained levels of high concentration of anti-D, 18 of the 28 male volunteers have received repeated antigenic stimuli at individual intervals of 2-9 months. In all but 1 case the level of anti-D rose to betw...

journal_title：Vox sanguinis

authors： Eklund J

更新日期：1978-01-01 00:00:00

abstract：:alpha 1-Antitrypsin (AAT) has been purified from human plasma supernatant A (equivalent to COHN fraction II + III) by a large-scale chromatographic procedure involving anion-exchange adsorption on DEAE Sepharose CL-6B fast flow and size-exclusion chromatography on Sephacryl S-200. Before freeze-drying, the liquid conc...

journal_title：Vox sanguinis

authors： Burnouf T,Constans J,Clerc A,Descamps J,Martinache L,Goudemand M

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aim of the study was to evaluate lyophilized monoclonal IgM anti-A and anti-B preparations for use as international standards (IS) to specify recommended minimum potencies of anti-A and anti-B blood grouping reagents in tube tests. MATERIALS AND METHODS:The candidate IS for minimum potenc...

journal_title：Vox sanguinis

authors： Thorpe SJ,Fox B,Heath AB,Scott M,de Haas M,Kochman S,Padilla A

更新日期：2006-11-01 00:00:00

abstract：:Sera from 2,829 participants in a population health survey were tested for the presence of a heterophilic antibody, detectable by immunofluorescence. The antibody was found in 9.8% of the sera from women and in 12.4% of the sera from men. The age-specific prevalence of the antibody was relatively constant in women but...

journal_title：Vox sanguinis

authors： Hawkins BR,Saueracker GC,Dawkins RL,Davey MG,O'Connor KJ

更新日期：1980-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:This study was undertaken to provide denominator data relating to the timing and location of transfusion, to support interpretation of reports of incorrect blood component transfused (IBCT) events to the UK Serious Hazards of Transfusion (SHOT) scheme. MATERIALS AND METHODS:The study was carr...

journal_title：Vox sanguinis

authors： Tinegate HN,Thompson CL,Jones H,Stainsby D

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Severe acute respiratory distress syndrome coronavirus-2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), is a member of the coronavirus family. Coronavirus infections in humans are typically associated with respiratory illnesses; however, viral RNA has been isolated in...

journal_title：Vox sanguinis

authors： Keil SD,Ragan I,Yonemura S,Hartson L,Dart NK,Bowen R

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Human platelet growth factors (HPGF) are essential for tissue regeneration and may replace fetal bovine serum (FBS) in cell therapy. No method for the manufacture of standardized virally inactivated HPGF has been developed yet. STUDY DESIGN AND METHODS:Platelet concentrates (PC) were subjected to solvent/de...

journal_title：Vox sanguinis

authors： Su CY,Kuo YP,Lin YC,Huang CT,Tseng YH,Burnouf T

更新日期：2009-08-01 00:00:00

abstract：:Haemolytic Disease of the Fetus and Newborn (HDFN) is caused by maternal alloimmunization against red blood cell antigens. In severe cases, HDFN may lead to fetal anaemia with a risk for fetal death and to severe forms of neonatal hyperbilirubinaemia with a risk for kernicterus. Most severe cases are caused by anti-D,...

journal_title：Vox sanguinis

authors： de Haas M,Thurik FF,Koelewijn JM,van der Schoot CE

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The para-Bombay phenotype (also known as H-deficient secretor) is characterized by a lack of ABH antigens on red cells, but ABH substances are found in saliva. Molecular genetic analysis was performed for five Chinese individuals serologically typed as para-Bombay. MATERIALS AND METHODS:ABO g...

journal_title：Vox sanguinis

authors： Yip SP,Chee KY,Chan PY,Chow EY,Wong HF

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Serologic tests for granulocyte antibodies, i.e., the granulocyte agglutination test and the granulocyte immunofluorescence test, require panels of typed granulocytes that cannot be preserved for more than a few hours. We have developed a new method in which granulocyte antigens, extracted int...

journal_title：Vox sanguinis

authors： Araki N,Nose Y,Kohsaki M,Mito H,Ito K

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The A2 is a very rare phenotype in the ABO blood group system in the Oriental population. It corresponds to a special ABO allele encoding a glycosyltransferase that is capable of synthesizing A2 antigens, which is weaker than the typical A antigen. In this study, we report a novel A2 allele in...

journal_title：Vox sanguinis

authors： Chen DP,Tseng CP,Wang WT,Sun CF

更新日期：2005-04-01 00:00:00

abstract：:We have employed a PCR approach to determine the nucleotide sequences of the coding region in the last two coding exons of the histo-blood group ABO genes from one A(X) and one B(A) individual. Compared with A1 alleles, the (A(X)) allele has a single nucleotide substitution (T-->A at nucleotide 646) resulting in an am...

journal_title：Vox sanguinis

authors： Yamamoto F,McNeill PD,Yamamoto M,Hakomori S,Harris T

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Early prediction of massive transfusion (MT) post-trauma may reduce mortality by earlier delivery of blood products. A clinical prediction tool (PWH score) for this purpose was developed at the Prince of Wales Hospital, Hong Kong. The aims of this study were to apply this tool to major trauma ...

journal_title：Vox sanguinis

authors： Mitra B,Rainer TH,Cameron PA

更新日期：2012-05-01 00:00:00

abstract：:The aim of this prospective study was to evaluate if there was a statistical correlation between allogeneic blood transfusion and postoperative infections, and if this could have a dose-dependent pattern. The evaluation was based on multiple logistic and receiver operating characteristics (ROC) curve analyses. On hosp...

journal_title：Vox sanguinis

authors： Vignali A,Braga M,Gianotti L,Radaelli G,Gentilini O,Russo A,Di Carlo V

更新日期：1996-01-01 00:00:00

abstract：:BACKGROUND  Whole blood (WB) donation encompasses several periods during which some donors faint. Identification of factors associated with fainting during each period should guide intervention strategies. Reducing faint reactions may reduce donor injuries and disability. METHODS  Blood donation was divided into three...

journal_title：Vox sanguinis

authors： Bravo M,Kamel H,Custer B,Tomasulo P

更新日期：2011-11-01 00:00:00

abstract：:The results obtained in a multicentre clinical trial of an enzyme immunoassay (EIA) method for hepatitis B surface antigen (HBsAg) (65,451 sera tested) have demonstrated that this new test has a significantly higher sensitivity than a reversed haemagglutination test (rHA). In a part of the trial, EIA was also compared...

journal_title：Vox sanguinis

authors： Kacaki J,Wolters G,Kuijpers L,Stulemeyer S

更新日期：1978-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Polymorphonuclear neutrophils (PMNs) play important roles in the host immune defence. This study was performed to identify roles of PMNs other than those already known. MATERIALS AND METHODS:PMNs were separated from the peripheral blood of healthy individuals and stored in vitro for 24 h in t...

journal_title：Vox sanguinis

authors： Nishimura M,Mitsunaga S,Juji T

更新日期：2002-04-01 00:00:00

abstract：:The etiologic agent for acquired immune deficiency syndrome (AIDS) has been identified as human T lymphotropic virus type III (HTLV-III). Its distinguishing characteristics and putative receptor, the T4 molecule, are discussed. The Western Blot method has been applied to assess the presence of antibody to HTLV-III in ...

journal_title：Vox sanguinis

authors： Pahwa S

更新日期：1986-01-01 00:00:00

abstract：:IgG subclasses differ not only in their biochemical and biologic properties, but also in their occurrence as selective deficiencies, alone and in combination. The normal range of IgG subclass concentrations in children and adults is compared with deficiencies found in individuals with repeated respiratory tract infect...

journal_title：Vox sanguinis

authors： Hanson LA,Björkander J,Robbins JB,Schneerson R,Söderström R,Söderström T

更新日期：1986-01-01 00:00:00