Science Without Conscience Is but the Ruin of the Soul: The Ethics of Big Data and Artificial Intelligence in Perioperative Medicine.

abstract：UNLABELLED:The purpose of this study was to determine whether different levels of pain would respond similarly to analgesia. We compared the analgesic response to ibuprofen in subjects with moderate versus severe baseline pain in clinical trials using the third molar post-extraction dental pain model. We performed a po...

journal_title：Anesthesia and analgesia

authors： Averbuch M,Katzper M

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Sigma (sigma)-receptor agonists attenuate brain injury after experimental focal cerebral ischemia in several species. We tested the hypothesis that the potent, prototypical sigma(1)-receptor agonist, 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP), protects neurons by a mechanism involving the antiapoptotic pro...

journal_title：Anesthesia and analgesia

authors： Yang S,Bhardwaj A,Cheng J,Alkayed NJ,Hurn PD,Kirsch JR

更新日期：2007-05-01 00:00:00

abstract：:Initial attempts at surgical anesthesia began many centuries ago, with the plants of antiquity. The mandragora, or mandrake, was used as a sedative and to induce pain relief for surgical procedures. It has been depicted in tablets and friezes since the 16th century before the common era (BCE) and used for its sedative...

journal_title：Anesthesia and analgesia

authors： Chidiac EJ,Kaddoum RN,Fuleihan SF

更新日期：2012-12-01 00:00:00

abstract：:The average duration of hospitalization after total knee arthroplasty (TKA) in the United States is 4-5 days. In this two-phase study we investigated the feasibility of converting TKA into an overnight-stay procedure using a continuous femoral nerve block provided at home through postoperative day 4. Nine of 10 patien...

journal_title：Anesthesia and analgesia

authors： Ilfeld BM,Gearen PF,Enneking FK,Berry LF,Spadoni EH,George SZ,Vandenborne K

更新日期：2006-01-01 00:00:00

abstract：:This randomized double-blind study compared the hemodynamic and metabolic effects of pancuronium and vecuronium during treatment of shivering after cardiac surgery with hypothermic cardiopulmonary bypass. Thirty sedated and pain-free patients who shivered after cardiac surgery were treated with pancuronium (n = 15) or...

journal_title：Anesthesia and analgesia

authors： Dupuis JY,Nathan HJ,DeLima L,Wynands JE,Russell GN,Bourke M

更新日期：1994-09-01 00:00:00

abstract：:The effects of narcotic agents and two inhalation anesthetics on intrabiliary pressure (IBP) were measured before and after morphine (0.2 mg/kg), meperidine (2 mg/kg), fentanyl (0.002 mg/kg), or pentazocine (1 mg/kg) given intramuscularly to guinea pigs, and after halothane (0.5, 1.0, 1.5, or 2.0 MAC) or enflurane (sa...

journal_title：Anesthesia and analgesia

authors： Arguelles JE,Franatovic Y,Romo-Salas F,Aldrete JA

更新日期：1979-03-01 00:00:00

abstract：:One of the most prevalent symptoms after major surgery is pain. When postoperative pain treatment is unsatisfactory, it can lead to poor surgical recovery, decreased quality of life, and increased health care costs. Current analgesics, single or in combination, have limited efficacy due to low potency, limited duratio...

journal_title：Anesthesia and analgesia

authors： Cata JP,Gorur A,Yuan X,Berg NK,Sood AK,Eltzschig HK

更新日期：2020-06-01 00:00:00

abstract：:We investigated the interaction between mivacurium and succinylcholine when mivacurium was administered during the early recovery from succinylcholine block. We studied 40 adult patients during propofol-alfentanil-N2O-O2 anesthesia. Neuromuscular function was monitored using an electromyographic method (Relaxograph, D...

journal_title：Anesthesia and analgesia

authors： Erkola O,Rautoma P,Meretoja OA

更新日期：1995-03-01 00:00:00

abstract：UNLABELLED:In this randomized, controlled study in dogs, we examined the short-term effects of blood pressure targeted fluid resuscitation with colloids or crystalloids solutions on systemic oxygen delivery, and lactate blood concentration. Fluid resuscitation using hydroxyethyl starch (HES) 6% to a mean arterial blood...

journal_title：Anesthesia and analgesia

authors： Friedman Z,Berkenstadt H,Preisman S,Perel A

更新日期：2003-01-01 00:00:00

abstract：UNLABELLED:Genitofemoral neuritis, which occurs when the neurolytic solution spreads into the psoas muscle, is the most common complication after neurolytic lumbar sympathetic block. We developed a transdiscal approach for neurolytic lumbar sympathetic block to reduce the danger of genitofemoral neuritis by making a sy...

journal_title：Anesthesia and analgesia

authors： Ohno K,Oshita S

更新日期：1997-12-01 00:00:00

abstract：UNLABELLED:The aim of this study was to investigate modern and classical electroencephalographic (EEG) variables in response to remifentanil and propofol infusions. We hypothesized that modern EEG variables may indicate the effects of propofol but not of remifentanil. Twenty-five patients were included in the study aft...

journal_title：Anesthesia and analgesia

authors： Schmidt GN,Bischoff P,Standl T,Voigt M,Papavero L,Schulte am Esch J

更新日期：2002-11-01 00:00:00

abstract：:In Japan, an ever-present problem in the preoperative evaluation of patients with ischemic heart disease is that although such evaluations are based on Western data, these data serve as the basis for determining perioperative risk in Japanese patients. To remedy this problem, the Cardiac Ischemia and Anesthesia Resear...

journal_title：Anesthesia and analgesia

authors： Seki M,Kashimoto S,Nagata O,Yoshioka H,Ishiguro T,Nishimura K,Honda O,Sakamoto A,Omi A,Ogihara Y,Fujimoto K,Iwade M,Yamada T,Nomura M,Takeda J

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:In the perioperative period, anesthesiologists and postanesthesia care unit (PACU) nurses routinely prepare and administer small-volume IV injections, yet the accuracy of delivered medication volumes in this setting has not been described. In this ex vivo study, we sought to characterize the degree to which ...

journal_title：Anesthesia and analgesia

authors： Muffly MK,Chen MI,Claure RE,Drover DR,Efron B,Fitch WL,Hammer GB

更新日期：2017-10-01 00:00:00

abstract：UNLABELLED:In this study, we examined the effectiveness of caudal blocks and correlated it with the laxity of the patients' anal sphincter before emergence from anesthesia in 178 children undergoing inguinal and/or penile surgery. Bupivacaine 0.25% in a volume of 0.6-1.25 mL/kg was used in all patients. The presence of...

journal_title：Anesthesia and analgesia

authors： Verghese ST,Mostello LA,Patel RI,Kaplan RF,Patel KM

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Neonates undergoing cardiac surgery are especially prone to the hemostatic alterations of cardiopulmonary bypass (CPB) and are at high risk for post-CPB bleeding. An immature coagulation system, significant hemodilution from the CPB prime, long CPB times at low temperatures, and extensive suture lines increa...

journal_title：Anesthesia and analgesia

authors： Guzzetta NA,Allen NN,Wilson EC,Foster GS,Ehrlich AC,Miller BE

更新日期：2015-02-01 00:00:00

abstract：UNLABELLED:The purpose of this study was to investigate whether propofol protects rat hepatocyte suspensions against an oxidant attack by a free radical generator 2,2'-azobis (2-amidinopropane) dihydrochloride (AAPH). Rat hepatocyte suspensions (2 x 10(6) cells/mL) were prepared using Seglen's collagenase perfusion tec...

journal_title：Anesthesia and analgesia

authors： Navapurkar VU,Skepper JN,Jones JG,Menon DK

更新日期：1998-11-01 00:00:00

abstract：:Adrenomedullin is a potent vasodilatory peptide. Plasma adrenomedullin (AM) concentrations increase during and after cardiopulmonary bypass (CPB). However, the cause of this increase and its site of production have not been identified. We investigated the role of the hepatosplanchnic and cerebral circulations in the i...

journal_title：Anesthesia and analgesia

authors： Yoshikawa D,Kawahara F,Okano N,Hiraoka H,Kadoi Y,Fujita N,Morita T,Goto F

更新日期：2003-09-01 00:00:00

abstract：UNLABELLED:The visual analog scale (VAS) is a tool widely used to measure pain, yet controversy surrounds whether the VAS score is ratio or ordinal data. We studied 52 postoperative patients and measured their pain intensity using the VAS. We then asked them to consider different amounts of pain (conceptually twice as ...

journal_title：Anesthesia and analgesia

authors： Myles PS,Troedel S,Boquest M,Reeves M

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:It has been shown that the combination of electroencephalogram (EEG) and auditory evoked potentials (AEP) allows a good separation of consciousness from unconsciousness. In the present study, we sought a combined EEG/AEP indicator that allows both separation of consciousness from unconsciousness and discrimi...

journal_title：Anesthesia and analgesia

authors： Horn B,Pilge S,Kochs EF,Stockmanns G,Hock A,Schneider G

更新日期：2009-05-01 00:00:00

abstract：UNLABELLED:Manufacturer's instructions recommend discarding unused portions of sodium thiopental 24 h after reconstitution. Heeding this recommendation may result in the disposal of a large proportion of prepared thiopental. Although thiopental is relatively inexpensive, the volume prepared by many anesthesia departmen...

journal_title：Anesthesia and analgesia

authors： Haws JL,Herman N,Clark Y,Bjoraker R,Jones D

更新日期：1998-01-01 00:00:00

abstract：:Sodium nitroprusside-induced cyanide intoxication has been demonstrated in the laboratory animal and has been experienced clinically during induced hypotensive anesthesia. This is a care report of a successful resuscitation of a severe cardiovascular collapse secondary to suspected sodium nitroprusside-induced cyanide...

journal_title：Anesthesia and analgesia

authors： Perschau RA,Modell JH,Bright RW,Shirley PD

更新日期：1977-07-01 00:00:00

abstract：:In a prospective, randomized, double-blind study, we investigated whether epinephrine increased the efficacy of levobupivacaine and sufentanil during epidural labor analgesia. Seventy term parturients received an epidural injection of levobupivacaine 0.125% and sufentanil 0.75 microg/mL with or without 1:800,000 epine...

journal_title：Anesthesia and analgesia

authors： Soetens FM,Soetens MA,Vercauteren MP

更新日期：2006-07-01 00:00:00

abstract：:The hemodynamic effects of an induction dose of propofol, 2.5 mg/kg, or etomidate, 0.3 mg/kg, were studied in eight dogs. In addition, cardiodynamic changes were measured using a left ventricular catheter and needle force probes. Propofol was associated with significant decreases in systolic (19.9%) and diastolic (25....

journal_title：Anesthesia and analgesia

authors： Brüssel T,Theissen JL,Vigfusson G,Lunkenheimer PP,Van Aken H,Lawin P

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Many of the complications of mechanical ventilation are related to inappropriate endotracheal tube (ETT) cuff pressure. The aim of the current study was to evaluate the effectiveness of automatic cuff pressure closed-loop control in patients under prolonged intubation, where presence of carbon dioxide (CO2) ...

journal_title：Anesthesia and analgesia

authors： Efrati S,Bolotin G,Levi L,Zaaroor M,Guralnik L,Weksler N,Levinger U,Soroksky A,Denman WT,Gurman GM

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Increasing costs of material resources challenge hospitals to stay profitable. Particularly in anesthesia departments and intensive care units, bronchoscopes are used for various indications. Inefficient management of single- and multiple-use systems can influence the hospitals' material costs substantially....

journal_title：Anesthesia and analgesia

authors： Edenharter GM,Gartner D,Pförringer D

更新日期：2017-06-01 00:00:00

abstract：IMPLICATIONS:The performance of regional blockade on a patient with a preexisting neurologic condition or a history of neurologic complications after regional anesthesia is controversial. We present a case of recurring brachial plexus neuropathy in a diabetic patient after two shoulder procedures performed 4 mo apart. ...

journal_title：Anesthesia and analgesia

authors： Horlocker TT,O'Driscoll SW,Dinapoli RP

更新日期：2000-09-01 00:00:00

abstract：UNLABELLED:We investigated the effects of isoflurane-induced burst suppression, monitored with electroencephalography (EEG), on cerebral blood flow velocity (CBFV), cerebral oxygen extraction (COE), and autoregulation in 16 patients undergoing cardiac surgery. The experimental procedure was performed during nonpulsatil...

journal_title：Anesthesia and analgesia

authors： Reinsfelt B,Westerlind A,Houltz E,Ederberg S,Elam M,Ricksten SE

更新日期：2003-11-01 00:00:00

abstract：:Forty neonates delivered by cesarean section were studied, half being delivered of mothers in whom anesthesia was induced with midazolam (0.3 mg/kg intravenously) and half of mothers given thiopental (4 mg/kg). At delivery, blood samples from mother and the umbilical vein were drawn for determination of plasma concent...

journal_title：Anesthesia and analgesia

authors： Bach V,Carl P,Ravlo O,Crawford ME,Jensen AG,Mikkelsen BO,Crevoisier C,Heizmann P,Fattinger K

更新日期：1989-03-01 00:00:00

abstract：:An early transesophageal echocardiography (TEE) study reported that there was high inter- and intraobserver variability in measurements of wall thickening (WT). This study reevaluated TEE for the measurement of WT in the transverse plane and, for the first time, evaluated it in the longitudinal plane. Ten patients wer...

journal_title：Anesthesia and analgesia

authors： Konstadt SN,Abrahams HP,Nejat M,Reich DL

更新日期：1994-04-01 00:00:00

abstract：:The anesthetic propofol (2,6 diisopropylphenol) mediates some of its effects by activating inhibitory chloride currents in the lower brainstem and spinal cord. The effects comprise direct activation of gamma-aminobutyric acid-A and glycine receptors in the absence of the natural agonist, as well as potentiation of the...

journal_title：Anesthesia and analgesia

authors： Ahrens J,Haeseler G,Leuwer M,Mohammadi B,Krampfl K,Dengler R,Bufler J

更新日期：2004-07-01 00:00:00