Late-life depression in people from ethnic minority backgrounds: Differences in presentation and management.

Abstract:

BACKGROUND:An elevated risk of late-life depression has been suggested in older adults from minority ethnic groups, but little is known about ethnic group differences in symptom and treatment profiles. The current study aimed to compare symptoms and types of treatment between ethnic groups in patients with late-life depression. METHODS:Data were extracted from the Clinical Record Interactive Search (CRIS) system , which provides access to the anonymised electronic health records of a large mental health care provider in South London. In total, 5,546 individuals aged 65 years and older, and diagnosed with late-life depression between 2006 and 2017, were included. Patients from ethnic minority backgrounds were compared to White British individuals on the following features recorded at depression diagnosis: mental and physical wellbeing,functional scales, individual depressive symptoms recorded, and treatments administered. RESULTS:Black Africans and Black Caribbeans more frequently presented with psychotic problems and were significantly less likely to have antidepressant treatment prescribed post diagnosis compared to White British. White Irish had higher rates of substance use and sleep disturbance. Depressive symptoms of hopelessness, guilt feelings, and suicidal thoughts were less common in Black Caribbeans, Black Africans, and South Asians compared to White British. LIMITATIONS:Only patients with depression under a specialist mental health care provider were included in the study. CONCLUSIONS:Ethnic minority elders have significantly different presentations and undertake different types of treatment both across groups and relative to their White British counterparts. These differences need to be taken into consideration to optimise pathways into care and to personalise treatment.

journal_name

J Affect Disord

authors

Mansour R,Tsamakis K,Rizos E,Perera G,Das-Munshi J,Stewart R,Mueller C

doi

10.1016/j.jad.2019.12.031

subject

Has Abstract

pub_date

2020-03-01 00:00:00

pages

340-347

eissn

0165-0327

issn

1573-2517

pii

S0165-0327(19)32927-1

journal_volume

264

pub_type

杂志文章
  • Are effects of depression management training for General Practitioners on patient outcomes mediated by improvements in the process of care?

    abstract:BACKGROUND:Depression treatment by General Practitioners (GPs) and patient outcomes improved significantly after a comprehensive 20-h training program of GPs. This study examines whether the effects on patient outcomes are caused by the improvements in the process of care. METHODS:Seventeen GPs participated in the tra...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/S0165-0327(03)00074-0

    authors: van Os TW,van den Brink RH,Tiemens BG,Jenner JA,van der Meer K,Ormel J

    更新日期:2004-06-01 00:00:00

  • What predicts persistent depression in older adults across Europe? Utility of clinical and neuropsychological predictors from the SHARE study.

    abstract:BACKGROUND:Depression in later life frequently persists and perpetuating factors are of immediate therapeutic relevance to clinicians. No studies of this scale have examined both clinical and neuropsychological predictors of persistent depression in a cross-national European context. METHODS:4095 community dwelling ol...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2012.10.037

    authors: Gallagher D,Savva GM,Kenny R,Lawlor BA

    更新日期:2013-05-01 00:00:00

  • The relationship between PTSD and suicidality among Wenchuan earthquake survivors: The role of PTG and social support.

    abstract:BACKGROUND:Previous studies have found that suicide rates are likely to increase after the occurrence of earthquakes. Most existing studies that examined the relationship between PTSD and suicidality focus on risk factors. It remains unclear whether protective factors, such as post-traumatic growth (PTG) and social sup...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2018.04.030

    authors: Guo J,Liu C,Kong D,Solomon P,Fu M

    更新日期:2018-08-01 00:00:00

  • Are female children more vulnerable to the long-term effects of maternal depression during pregnancy?

    abstract:BACKGROUND:Female fetuses are more vulnerable to high levels of maternal glucocorticoids. We examined whether exposure to prenatal maternal depression, a condition associated with high glucocorticoids, carries greater risk for depression at 12 and 18 years in girls. METHODS:Our sample comprised 7959 mothers and childr...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2015.09.039

    authors: Quarini C,Pearson RM,Stein A,Ramchandani PG,Lewis G,Evans J

    更新日期:2016-01-01 00:00:00

  • Schizoaffective disorder diagnosed according to different diagnostic criteria--systematic literature search and meta-analysis of key clinical characteristics and heterogeneity.

    abstract:BACKGROUND:Schizoaffective disorder is viewed as a heterogeneous diagnosis among psychotic illnesses. Different diagnostic systems differ in their definition with DSM (-IIIR, -IV, and -V) providing a narrower definition than RDC and ICD-10. It is unclear whether this difference is reflected in patient samples diagnosed...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.jad.2013.12.001

    authors: Pagel T,Franklin J,Baethge C

    更新日期:2014-03-01 00:00:00

  • Plasma GABA in affective illness. A preliminary investigation.

    abstract::Plasma levels of gamma-aminobutyric acid (GABA) were determined in 34 clinically symptomatic patients with diagnosis of affective disorder and in 20 normal controls. Lowest levels were found in patients with familial pure depressive disease and in depression spectrum disease, while levels of patients with sporadic dep...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/0165-0327(81)90003-3

    authors: Petty F,Schlesser MA

    更新日期:1981-12-01 00:00:00

  • Electrodermal hyporeactivity and antisocial behavior: does anxiety mediate the relationship?

    abstract::Electrodermal hyporeactivity in the anticipation of aversive stimuli is a highly reliable correlate of diagnosed psychopathy and undersocialized aggressive conduct disorder (UACD), and it has been interpreted as reflecting a weak behavioral inhibition system (BIS) as conceptualized in Gray's work (e.g., in: Royce, J.R...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,评审

    doi:10.1016/s0165-0327(00)00336-0

    authors: Fowles DC

    更新日期:2000-12-01 00:00:00

  • "Diminished" association between the serotonin transporter linked polymorphism (5HTTLPR) and body mass index in a large psychiatric sample.

    abstract:BACKGROUND:The role of the promoter polymorphism (5HTTLPR) of the serotonin transporter gene (SLC6A4) in psychiatric illnesses has been studied extensively. Serotonergic function also regulates many central nervous system, including appetite and feeding behaviors. The 5HTTLPR short allele was found to be associated wit...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2013.06.021

    authors: Shinozaki G,Kumar Y,Rosen BH,Rundell JR,Mrazek DA,Kung S

    更新日期:2013-10-01 00:00:00

  • A systematic review of cognitive remediation for schizo-affective and affective disorders.

    abstract:BACKGROUND:Cognitive remediation is accepted as an important therapeutic intervention in schizophrenia, but few studies provide data on whether the benefits extend to affective disorders. OBJECTIVES:To review quantitatively studies of cognitive remediation with samples that included cases of schizoaffective disorder, ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.jad.2012.04.020

    authors: Anaya C,Martinez Aran A,Ayuso-Mateos JL,Wykes T,Vieta E,Scott J

    更新日期:2012-12-15 00:00:00

  • Decreased platelet 3H-imipramine binding in primary major depression compared with depression secondary to medical illness in elderly outpatients.

    abstract::Platelet 3H-imipramine binding and monoamine oxidase (MAO) activity were investigated in elderly outpatients with primary major depression, and in a group with depression secondary to medical illness (organic mood disorder, depressed by DSM-III-R criteria) in a multidisciplinary geriatric clinic. The density of the bi...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/0165-0327(88)90091-2

    authors: Schneider LS,Severson JA,Sloane RB,Fredrickson ER

    更新日期:1988-09-01 00:00:00

  • Differential interactions between comorbid anxiety disorders and substance use disorder in rapid cycling bipolar I or II disorder.

    abstract:OBJECTIVE:Anxiety disorders (AD) and substance use disorders (SUD) commonly co-occur with bipolar disorder. This study was undertaken to assess AD-SUD-bipolar subtype interactions. METHODS:Extensive clinical interview and MINI were used to ascertain DSM-IV diagnoses of rapid cycling bipolar I (RCBPDI) or II (RCBPDII) ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2007.12.229

    authors: Gao K,Tolliver BK,Kemp DE,Verduin ML,Ganocy SJ,Bilali S,Brady KT,Shim SS,Findling RL,Calabrese JR

    更新日期:2008-09-01 00:00:00

  • Type 2 diabetes and pre-diabetic abnormalities in patients with bipolar disorders.

    abstract:BACKGROUND:Abnormalities in the glucose metabolism cause nervous and organic damage and are a cardiovascular risk factor. They could be a main cause for the increased morbidity and mortality rates found in patients with bipolar disorders. The exact prevalence of diabetes and pre-diabetic abnormalities, however, is not ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2015.09.041

    authors: Leopold K,Reif A,Haack S,Bauer M,Bury D,Löffler A,Kittel-Schneider S,Pfeiffer S,Sauer C,Schwarz P,Pfennig A

    更新日期:2016-01-01 00:00:00

  • Changes in method specific suicide following a national pesticide ban in India (2011-2014).

    abstract:BACKGROUND:This paper investigates whether declines in suicide by insecticide poisoning in India following a national ban on endosulfan in 2011were associated with changes in other methods of suicide and total suicide rates. METHOD:Method-specific suicide rates between 2001-2014 were calculated using National Crime Re...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2020.09.085

    authors: Arya V,Page A,Gunnell D,Armstrong G

    更新日期:2021-01-01 00:00:00

  • Cerebrospinal fluid levels of amitriptyline, nortriptyline, imipramine and desmethylimipramine. Relationship to plasma levels and treatment outcome.

    abstract::Fifty-five (55) depressed patients were treated with amitriptyline (AMI) or imipramine (IMI). Concentrations of AMI, IMI, and their metabolites, nortriptyline (NT) and desmethylimipramine (DMI), were measured in cerebrospinal fluid (CSF) and plasma at steady state by gas chromatography mass spectrometry (GC/MS). Highl...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/0165-0327(85)90012-6

    authors: Hanin I,Koslow SH,Kocsis JH,Bowden CL,Brunswick D,Frazer A,Carl J,Robins E

    更新日期:1985-07-01 00:00:00

  • The dexamethasone suppression test in acute mania.

    abstract::The dexamethasone suppression test was administered to 40 newly admitted manic patients. Twenty-four patients (60%) had abnormal escape from suppression. There was no correlation of DST results with sex, age, age of onset, family history of affective disorder, psychosis during index episode, or duration of hospitaliza...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/0165-0327(84)90049-1

    authors: Godwin CD

    更新日期:1984-12-01 00:00:00

  • Prevalence and comorbidity of affective disorders in persons making suicide attempts in Hungary: importance of the first depressive episodes and of bipolar II diagnoses.

    abstract:BACKGROUND:The purpose of this study was to investigate the prevalence and comorbidity of affective disorders, especially current major depressive episode and bipolar disorder among suicide attempters in Hungary. METHODS:Using a structured interview (Mini International Neuropsychiatric Interview) determining 16 Axis I...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/s0165-0327(02)00084-8

    authors: Balázs J,Lecrubier Y,Csiszér N,Koszták J,Bitter I

    更新日期:2003-09-01 00:00:00

  • Association between catechol-O-methyltransferase Val(108/158)Met polymorphism and psychotic features of bipolar disorder.

    abstract:BACKGROUND:Catechol-O-methyltransferase (COMT) inactivates catecholamines, and a G-A transition in the COMT gene (rs4680) influences the enzyme activity and the interaction between cortical and subcortical dopaminergic neurotransmission. Studies in healthy participants and in patients affected by schizophrenia suggeste...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2010.01.005

    authors: Benedetti F,Dallaspezia S,Colombo C,Lorenzi C,Pirovano A,Smeraldi E

    更新日期:2010-09-01 00:00:00

  • A comparative cross-cultural study of the prevalence of late life depression in low and middle income countries.

    abstract:BACKGROUND:Current estimates of the prevalence of depression in later life mostly arise from studies carried out in Europe, North America and Asia. In this study we aimed to measure the prevalence of depression using a standardised method in a number of low and middle income countries (LMIC). METHODS:A one-phase cross...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2015.09.004

    authors: Guerra M,Prina AM,Ferri CP,Acosta D,Gallardo S,Huang Y,Jacob KS,Jimenez-Velazquez IZ,Llibre Rodriguez JJ,Liu Z,Salas A,Sosa AL,Williams JD,Uwakwe R,Prince M

    更新日期:2016-01-15 00:00:00

  • A meta-analysis of psychotherapy and medication in unipolar depression and dysthymia.

    abstract:BACKGROUND:There remains considerable disagreement regarding the relative efficacy of psychotherapy and medication across types of depression. METHOD:We used random effects meta-analysis to examine the relative efficacy of psychotherapy vis-à-vis medication at post-treatment and follow-up. We also estimated the relati...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.jad.2008.03.018

    authors: Imel ZE,Malterer MB,McKay KM,Wampold BE

    更新日期:2008-10-01 00:00:00

  • Emotionally valenced stimuli impact response inhibition in those with substance use disorder and co-occurring anxiety and depression symptoms.

    abstract:BACKGROUND:Substance use disorder (SUD) is associated with impaired response inhibition. Given the deficits in emotion regulation associated with SUD, it is unclear if this impairment is exacerbated by emotionally valenced stimuli. Co-occurring conditions may further exacerbate these impairments as many co-occurring co...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2020.02.008

    authors: Legrand AC,Price M

    更新日期:2020-04-01 00:00:00

  • Quetiapine and classical mood stabilizers in the long-term treatment of Bipolar Disorder: a 4-year follow-up naturalistic study.

    abstract:BACKGROUND:The aim of this naturalistic study was to compare the effectiveness of quetiapine and classical mood stabilizers, as mono- or combination therapy, in the long-term treatment of Bipolar Disorder (BD). METHODS:232 DSM-IV BD I (n=91) or BD II (n=141) patients, treated and followed up for four years, were studi...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2008.01.017

    authors: Altamura AC,Mundo E,Dell'Osso B,Tacchini G,Buoli M,Calabrese JR

    更新日期:2008-09-01 00:00:00

  • Duloxetine enters the brain - But why is it not found in the cerebrospinal fluid.

    abstract:BACKGROUND:Antidepressants enter the brain to reach their site of action in a different extent. However, there has been no study to date about duloxetine's ability to enter the brain and cerebrospinal fluid. Aim of this study was to measure blood and cerebrospinal fluid concentrations of duloxetine and to account for t...

    journal_title:Journal of affective disorders

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.jad.2015.08.073

    authors: Paulzen M,Gründer G,Veselinovic T,Wolf B,Hiemke C,Lammertz SE

    更新日期:2016-01-01 00:00:00

  • Mauling of the "Celtic Tiger": clinical characteristics and outcome of first-episode depression secondary to the economic recession in Ireland.

    abstract:BACKGROUND:There is a dearth of studies describing clinical characteristics and outcome of patients who present with mood disorders related to economic recession. AIMS:To describe a cohort of patients admitted with first-episode depression related to the Irish economic recession and compare this cohort with all other ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2013.06.024

    authors: Thekiso TB,Heron EA,Masood B,Murphy M,McLoughlin DM,Kennedy N

    更新日期:2013-11-01 00:00:00

  • Couples' relationship affects mothers' and fathers' anxiety and depression trajectories over the transition to parenthood.

    abstract:BACKGROUND:The association between the couple relationship and the mothers' and fathers' psychological adjustment to the transition to parenthood has been examined in the literature. However, the direction of effects between these variables has not been extensively explored. This study aimed to assess the direction of ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2018.05.064

    authors: Figueiredo B,Canário C,Tendais I,Pinto TM,Kenny DA,Field T

    更新日期:2018-10-01 00:00:00

  • Evaluating the new ICD-10 categories of depressive episode and recurrent depressive disorder.

    abstract::The new ICD-10 categories of 'depressive episode' (F32) and 'recurrent depressive disorder' (F33) were evaluated on the levels of diagnoses, subtypes, syndromes and symptoms. Interrater reliability was analyzed from findings of four independent diagnosticians who rated 100 written psychiatric case records with the hel...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/0165-0327(94)90126-0

    authors: Hiller W,Dichtl G,Hecht H,Hundt W,Mombour W,von Zerssen D

    更新日期:1994-05-01 00:00:00

  • Affective symptoms at index hospitalization in childhood and depressive symptoms in adulthood: a "catch-up" study.

    abstract:PURPOSE:To analyze whether affective symptoms during psychiatric treatment in childhood or adolescence could predict the later development of depressive symptoms. METHOD:We used a "catch-up" design. A cohort of former child and adolescent psychiatric patients was assessed in adulthood with standardized instruments acc...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/s0165-0327(00)00302-5

    authors: Brieger P,Blöink R,Sommer S,Marneros A

    更新日期:2001-10-01 00:00:00

  • Folates and post partum depression.

    abstract::Hypofolatemia can cause psychiatric disturbances of a depressive nature. Pregnancy and delivery are often associated with hypofolatemia. This study was conducted to determine if hypofolatemia at day 3 post partum is a risk factor for baby blues or post partum depression. To study this hypothesis, 131 post partum women...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/0165-0327(92)90081-g

    authors: Rouillon F,Thalassinos M,Miller HD,Lemperiere T

    更新日期:1992-08-01 00:00:00

  • Altered plasma protein glycosylation in a mouse model of depression and in patients with major depression.

    abstract:BACKGROUND:Glycosylation is a common posttranslational modification in protein biosynthesis that is implicated in several disease states. It has been reported that specific protein glycan structures are useful as biomarkers for cancer and some neuropsychiatric diseases; however, the relationship between plasma protein ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2017.08.057

    authors: Yamagata H,Uchida S,Matsuo K,Harada K,Kobayashi A,Nakashima M,Higuchi F,Watanuki T,Matsubara T,Watanabe Y

    更新日期:2018-06-01 00:00:00

  • Therapist-rated outcomes in a randomized clinical trial comparing cognitive behavioral therapy and psychodynamic therapy for major depression.

    abstract:BACKGROUND:The efficacy of psychodynamic therapy (PDT) for depression is debated due to a paucity of high-quality studies. We compared short psychodynamic supportive psychotherapy (SPSP) to cognitive behavioral therapy (CBT) in a randomized clinical trial. We used therapist-rated outcomes to examine how the course of c...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jad.2014.08.023

    authors: Driessen E,Van Henricus L,Peen J,Don FJ,Kool S,Westra D,Hendriksen M,Cuijpers P,Twisk JW,Dekker JJ

    更新日期:2015-01-01 00:00:00

  • More adaptive versus less maladaptive coping: What is more predictive of symptom severity? Development of a new scale to investigate coping profiles across different psychopathological syndromes.

    abstract:BACKGROUND:Lack of adaptive and enhanced maladaptive coping with stress and negative emotions are implicated in many psychopathological disorders. We describe the development of a new scale to investigate the relative contribution of different coping styles to psychopathology in a large population sample. We hypothesiz...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2015.11.027

    authors: Moritz S,Jahns AK,Schröder J,Berger T,Lincoln TM,Klein JP,Göritz AS

    更新日期:2016-02-01 00:00:00