Folates and post partum depression.

Abstract:

:Hypofolatemia can cause psychiatric disturbances of a depressive nature. Pregnancy and delivery are often associated with hypofolatemia. This study was conducted to determine if hypofolatemia at day 3 post partum is a risk factor for baby blues or post partum depression. To study this hypothesis, 131 post partum women were followed prospectively for the 3 months immediately following delivery. 19% were found to have 'baby blues', as defined by a score greater than 20 on Pitt's scale (Pitt, 1968, J. Psychiatry 114, 1325-1335) and 12% had post partum depression as defined by a score greater than 7 on QD2A scale (Pichot et al., 1984, Rev. Psycholog. App. 34, 229-250, 323-340), within the three months post partum. No relationship was observed between the serum or erythrocyte folate levels on the third day following delivery and the maternal post partum depression scores. A statistically significant correlation between post partum depression and previous psychiatric disturbance was, however, observed.

journal_name

J Affect Disord

authors

Rouillon F,Thalassinos M,Miller HD,Lemperiere T

doi

10.1016/0165-0327(92)90081-g

subject

Has Abstract

pub_date

1992-08-01 00:00:00

pages

235-41

issue

4

eissn

0165-0327

issn

1573-2517

pii

0165-0327(92)90081-G

journal_volume

25

pub_type

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