当前位置： SCI文献检索 > JOURNAL OF AFFECTIVE DISORDERS期刊下所有文献 > Altered plasma protein glycosylation in a mouse model of depression and in patients with major depression.

Altered plasma protein glycosylation in a mouse model of depression and in patients with major depression.

Abstract：

BACKGROUND:Glycosylation is a common posttranslational modification in protein biosynthesis that is implicated in several disease states. It has been reported that specific protein glycan structures are useful as biomarkers for cancer and some neuropsychiatric diseases; however, the relationship between plasma protein glycosylation and major depressive disorder (MDD) has not been investigated to date. The aim of this study was to determine whether plasma protein glycan structures are altered in depression using a stress-based mouse model and samples from patients with MDD. METHODS:We used chronic ultra-mildly stressed mice that were untreated or treated with imipramine as mouse models of depression and remission, respectively. We also made comparisons between samples from depressed and remitted patients with MDD. Protein glycosylation was analyzed using a lectin microarray that included 45 lectins with binding affinities for various glycan structures. RESULTS:Sia-alpha2-6Gal/GalNAc was a commonly altered glycan structure in both depression model mice and patients with MDD. Moreover, the expression of ST6GALNAC2 was decreased in leukocytes from patients with MDD. LIMITATIONS:Our study samples were small and we did not identify specific alpha2-6Gal/GalNAc-sialylated proteins. CONCLUSIONS:The glycan structure Sia-alpha2-6GalNAc in plasma protein and ST6GALNAC2 expression in peripheral leukocytes may have utility as candidate biomarkers for the clinical diagnosis and monitoring of MDD.

journal_name

J Affect Disord

journal_title

Journal of affective disorders

authors

Yamagata H,Uchida S,Matsuo K,Harada K,Kobayashi A,Nakashima M,Higuchi F,Watanuki T,Matsubara T,Watanabe Y

doi

10.1016/j.jad.2017.08.057

subject

Has Abstract

pub_date

2018-06-01 00:00:00

pages

79-85

eissn

0165-0327

issn

1573-2517

pii

S0165-0327(17)31110-2

journal_volume

233

pub_type

杂志文章

相关文献

JOURNAL OF AFFECTIVE DISORDERS文献大全
  • Early risk factors for postpartum depression: A longitudinal Japanese population-based study.

    abstract：BACKGROUND:Postpartum depression (PPD) negatively impacts maternal health, parenting and development of children. Most previous studies on PPD risk factors are based on Western populations. Additionally, little is known about the association between psychosocial factors during early pregnancy period and PPD. We aimed t...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2020.03.026

    authors： Nakano M,Sourander A,Luntamo T,Chudal R,Skokauskas N,Kaneko H

    更新日期：2020-05-15 00:00:00

  • Serotonin transporter clustering in blood lymphocytes as a putative biomarker of therapeutic efficacy in major depressive disorder.

    abstract：BACKGROUND:Serotonin transporter (SERT) binding is decreased in lymphocytes of depression patients and this decrease is partially reversed by antidepressant medication. However, recent evidence has shown that clustering of SERT on cell membranes is very important for receptor functionality. Alteration in SERT clusterin...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2011.12.041

    authors： Rivera-Baltanas T,Olivares JM,Calado-Otero M,Kalynchuk LE,Martinez-Villamarin JR,Caruncho HJ

    更新日期：2012-03-01 00:00:00

  • Delta sleep EEG in depressed adolescent females and healthy controls.

    abstract：BACKGROUND:Quantitative EEG studies have identified a number of sleep abnormalities in adults with major depressive disorders (MDD), including a reduction in the amplitude of delta activity during NREM sleep. To date, these methodologies have not been used in early onset MDD. METHODS:Delta activity during NREM sleep w...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/s0165-0327(00)00194-4

    authors： Armitage R,Emslie GJ,Hoffmann RF,Rintelmann J,Rush AJ

    更新日期：2001-03-01 00:00:00

  • Attachment representations, patterns of emotion regulation, and social exclusion in patients with chronic and episodic depression and healthy controls.

    abstract：BACKGROUND:The experience of social exclusion (ostracism) is linked to the etiology and maintenance of depression. Most individuals experience emotional stress in states of social exclusion. Insecurely attached individuals, especially with an unresolved trauma, show maladaptive coping in response to social stress. The ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2016.12.030

    authors： Bauriedl-Schmidt C,Jobst A,Gander M,Seidl E,Sabaß L,Sarubin N,Mauer C,Padberg F,Buchheim A

    更新日期：2017-03-01 00:00:00

  • Emotion reactivity, nonsuicidal self-injury, and regulatory emotional self-efficacy: A moderated mediation model of suicide ideation.

    abstract：BACKGROUND:Adolescent suicide ideation (SI) has received increased attention in recent years, and emotion reactivity (ER) has been found to be a risk factor for SI. However, little is known about the mediating and moderating mechanisms underlying this relationship. The aim of this study is to test a moderated mediation...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2020.01.083

    authors： Liu S,You J,Ying J,Li X,Shi Q

    更新日期：2020-04-01 00:00:00

  • Validation of the Italian version of interpersonal sensitivity measure (IPSM) in adolescents and young adults.

    abstract：BACKGROUND:Interpersonal sensitivity is a personality trait that describes as excessive awareness of both the behaviour and feelings of others. High interpersonal sensitivity has been associated with the development and maintenance of mental health problems. This study aimed to examine whether the Italian version of th...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2013.12.012

    authors： Masillo A,Valmaggia LR,Lanna A,Brandizzi M,Lindau JF,Curto M,Solfanelli A,Kotzalidis GD,Patanè M,Godeas L,Leccisi D,Girardi P,Fiori Nastro P

    更新日期：2014-03-01 00:00:00

  • Association between the TPH1 A218C polymorphism and risk of mood disorders and alcohol dependence: evidence from the current studies.

    abstract：BACKGROUND:Several studies have assessed the association between genetic polymorphisms of tryptophan hydroxylase (TPH1) and risk of mood disorders and alcohol dependence, with controversial results. Our aim was to assess the association of TPH1 A218C polymorphism (rs1800532) with mood disorders, including major depress...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.jad.2011.04.018

    authors： Chen D,Liu F,Yang C,Liang X,Shang Q,He W,Wang Z

    更新日期：2012-04-01 00:00:00

  • Early and late onset bipolar disorders: two different forms of manic-depressive illness?

    abstract：BACKGROUND:Conflicting results in genetic studies of bipolar disorders may be due to the clinical and genetic heterogeneity of the disease. Age at onset of bipolar disorders may be a key indicator for identifying more homogeneous clinical subtypes. We tested whether early onset and late onset bipolar illness represent ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/s0165-0327(99)00111-1

    authors： Schürhoff F,Bellivier F,Jouvent R,Mouren-Siméoni MC,Bouvard M,Allilaire JF,Leboyer M

    更新日期：2000-06-01 00:00:00

  • Association between serum BDNF levels and maternal perinatal depression: A review: Special Section on "Translational and Neuroscience Studies in Affective Disorders" Section Editor, Maria Nobile MD, PhD.

    abstract：INTRODUCTION:A large amount of studies demonstrated reduced serum Brain-Derived Neurotrophic Factor (BDNF) levels in stress-related and depressive disorders. However, it is still unclear if a similar deficit in BDNF concentrations might also characterize maternal perinatal depression. METHODS:We performed a bibliograp...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2019.08.007

    authors： Mandolini GM,Lazzaretti M,Delvecchio G,Bressi C,Soares JC,Brambilla P

    更新日期：2020-01-15 00:00:00

  • Regional cortical thinning and cerebral hypoperfusion in patients with panic disorder.

    abstract：BACKGROUND:Although recent neuroimaging studies have suggested that functional deficits in facial perception are associated with panic disorder (PD), the possibility of cortical thickness and perfusion abnormalities have not been studied in patients with PD. We aimed to investigate alterations in cortical thickness and...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2020.07.139

    authors： Ni MF,Wang XM,Wang HY,Chang Y,Huang XF,Zhang BW

    更新日期：2020-12-01 00:00:00

  • Risk of attempted suicide among adolescents and young adults with traumatic brain injury: A nationwide longitudinal study.

    abstract：BACKGROUND:Traumatic brain injury (TBI) and suicidal behavior lead to serious morbidity and premature mortality. TBI in adulthood is associated with a higher incidence of suicide, but the risk in adolescents and young adults is not clear. METHODS:Longitudinal follow-up data were extracted from a National Health Insura...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2019.02.059

    authors： Chang HK,Hsu JW,Wu JC,Huang KL,Chang HC,Bai YM,Chen TJ,Chen MH

    更新日期：2019-05-01 00:00:00

  • Psychological distress and the incident risk of functional disability in elderly survivors after the Great East Japan Earthquake.

    abstract：BACKGROUND:We conducted a prospective cohort study to investigate whether psychological distress would have increased the incident risk of functional disability after the 2011 Great East Japan Earthquake. METHODS:First phase data pertaining to psychological distress and other lifestyle factors were collected from 1037...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2017.06.030

    authors： Tanji F,Sugawara Y,Tomata Y,Watanabe T,Sugiyama K,Kaiho Y,Tomita H,Tsuji I

    更新日期：2017-10-15 00:00:00

  • An examination of the structure of posttraumatic stress disorder in relation to the anxiety and depressive disorders.

    abstract：:The nature and structure of posttraumatic stress disorder (PTSD) has been the subject of much interest in recent times. This research has been represented by two streams, the first representing a substantive body of work which focuses specifically on the factor structure of PTSD and the second exploring PTSD's relatio...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2011.02.011

    authors： Forbes D,Lockwood E,Elhai JD,Creamer M,O'Donnell M,Bryant R,McFarlane A,Silove D

    更新日期：2011-07-01 00:00:00

  • Sudarshan Kriya Yoga improves cardiac autonomic control in patients with anxiety-depression disorders.

    abstract：BACKGROUND:Several studies have demonstrated that adjuvant therapies as exercise and breathing training are effective in improving cardiac autonomic control (CAC) in patients with affective spectrum disorders. However, the effects of Sudarshan Kriya Yoga (SKY) on autonomic function in this population is unknown. Our ob...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2017.03.017

    authors： Toschi-Dias E,Tobaldini E,Solbiati M,Costantino G,Sanlorenzo R,Doria S,Irtelli F,Mencacci C,Montano N

    更新日期：2017-05-01 00:00:00

  • Obsessive-compulsive disorder has a reduced placebo (and antidepressant) response compared to other anxiety disorders: A meta-analysis.

    abstract：BACKGROUND:Previous studies have indicated that obsessive-compulsive disorder (OCD) might have a reduced placebo response compared to other anxiety-related disorders including generalized anxiety disorder, panic disorder, post-traumatic stress disorder, and social anxiety disorder. No previous analysis has directly com...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.jad.2017.04.068

    authors： Sugarman MA,Kirsch I,Huppert JD

    更新日期：2017-08-15 00:00:00

  • Association of salivary cortisol levels and later depressive state in elderly people living in a rural community: a 3-year follow-up study.

    abstract：BACKGROUND:Late-life depressive disorder is becoming an important issue in health economics in the world, as it has been reported to be one of major risk factors for incidence of dementia. Identification of predictive markers associated with depression in later life is therefore of high priority in public health. The a...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2014.02.003

    authors： Nabeta H,Mizoguchi Y,Matsushima J,Imamura Y,Watanabe I,Tateishi T,Kojima N,Kawashima T,Yamada S,Monji A

    更新日期：2014-04-01 00:00:00

  • Insomnia and hypersomnia in major depressive episode: Prevalence, sociodemographic characteristics and psychiatric comorbidity in a population-based study.

    abstract：OBJECTIVES:To examine (i) the frequency of different sleep complaints (early wake-up, trouble falling asleep, hypersomnia) and their co-occurrence and (ii) the sociodemographic characteristics and psychiatric comorbidity associated with each type of sleep profiles. METHODS:Data were drawn from the Wave 2 National Epid...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2017.09.032

    authors： Geoffroy PA,Hoertel N,Etain B,Bellivier F,Delorme R,Limosin F,Peyre H

    更新日期：2018-01-15 00:00:00

  • The role of prenatal social support in social inequalities with regard to maternal postpartum depression according to migrant status.

    abstract：BACKGROUND:An advantaged socioeconomic position (SEP) and satisfying social support during pregnancy (SSP) have been found to be protective factors of maternal postpartum depression (PDD). An advantaged SEP is also associated with satisfying SSP, making SSP a potential mediator of social inequalities in PPD. SEP, SSP a...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2020.04.024

    authors： Nakamura A,El-Khoury Lesueur F,Sutter-Dallay AL,Franck JÈ,Thierry X,Melchior M,van der Waerden J

    更新日期：2020-07-01 00:00:00

  • Impairments in episodic future thinking for positive events and anticipatory pleasure in major depression.

    abstract：BACKGROUND:Characteristic of the cardinal symptom of anhedonia, people with clinical depression report lower levels of anticipatory pleasure. However, the psychological mechanisms underlying these deficits are poorly understood. This is the first study to assess whether, and to what extent, phenomenological characteris...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2019.09.039

    authors： Hallford DJ,Barry TJ,Austin DW,Raes F,Takano K,Klein B

    更新日期：2020-01-01 00:00:00

  • The relationship between temperament and sexual orientation.

    abstract：BACKGROUND:The relationship between temperament and sexual orientation has been poorly characterized. We have used the Affective and Emotional Composite Temperament (AFECT) model to evaluate this association in a large population sample. METHODS:Data from 16,571 subjects between 21 and 45 years old (mean age=29.1±6.3 ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2015.01.029

    authors： Guerim LD,de Carvalho HW,Lara DR

    更新日期：2015-04-01 00:00:00

  • Cumulative incidence of suicidal ideation and associated factors among adults living in temporary housing during the three years after the Great East Japan Earthquake.

    abstract：BACKGROUND:The effect of disasters on suicidality is not known. We aimed to retrospectively determine the cumulative incidence of suicidal ideation during the 3 years after the Great East Japan Earthquake among residents in temporary housing without prior suicidal ideation, as compared to the general population. Moreov...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2018.01.021

    authors： Xu Q,Fukasawa M,Kawakami N,Baba T,Sakata K,Suzuki R,Tomita H,Nemoto H,Yasumura S,Yabe H,Horikoshi N,Umeda M,Suzuki Y,Shimoda H,Tachimori H,Takeshima T,Bromet EJ

    更新日期：2018-05-01 00:00:00

  • Adverse childhood experiences and the risk of depressive disorders in adulthood.

    abstract：BACKGROUND:Research examining the association between childhood abuse and depressive disorders has frequently assessed abuse categorically, thus not permitting discernment of the cumulative impact of multiple types of abuse. As previous research has documented that adverse childhood experiences (ACEs) are highly interr...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2003.12.013

    authors： Chapman DP,Whitfield CL,Felitti VJ,Dube SR,Edwards VJ,Anda RF

    更新日期：2004-10-15 00:00:00

  • Exercise and severe depression: preliminary results of an add-on study.

    abstract：BACKGROUND:Physical exercise has been extensively researched as a therapeutic option for treatment of major depression. METHODS:In a randomized controlled trial, we analyze the effects of aerobic physical exercise as an add-on strategy for treatment of severe depressed inpatients. The exercise has a "Dose" of 16.5 kca...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jad.2011.04.030

    authors： Schuch FB,Vasconcelos-Moreno MP,Borowsky C,Fleck MP

    更新日期：2011-10-01 00:00:00

  • Suicide in the United States Air Force: Risk factors communicated before and at death.

    abstract：BACKGROUND:Over the last decade, suicide rates in the U.S. military have steadily increased, resulting in a call for suicide-related research with military populations. The present project aimed to describe and evaluate the communications (i.e., verbally and in suicide notes) of 13 suicide risk factors in the suicide d...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2011.05.011

    authors： Cox DW,Ghahramanlou-Holloway M,Greene FN,Bakalar JL,Schendel CL,Nademin ME,Jobes DA,Englert DR,Kindt M

    更新日期：2011-10-01 00:00:00

  • Polysomnographic features of early-onset depression: a meta-analysis.

    abstract：BACKGROUND:Undiagnosed major depressive disorder (MDD) is associated with increased morbidity in children and adolescents. This study evaluated features of sleep macro- and microarchitecture assessed by polysomnography (PSG) as diagnostic markers for MDD in children and adolescents. METHODS:MEDLINE, PSYCINFO, EMBASE a...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.jad.2013.12.009

    authors： Augustinavicius JL,Zanjani A,Zakzanis KK,Shapiro CM

    更新日期：2014-04-01 00:00:00

  • Swimming exercise reverses CUMS-induced changes in depression-like behaviors and hippocampal plasticity-related proteins.

    abstract：BACKGROUND:Stress-induced failed resilience of brain plasticity can contribute to the onset and recurrence of depression. Chronic stress has been reported to open windows of epigenetic plasticity in hippocampus. However, how hippocampal plasticity underlies depression-like behaviors and how it adapts in response to str...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2017.10.019

    authors： Liu W,Xue X,Xia J,Liu J,Qi Z

    更新日期：2018-02-01 00:00:00

  • Decreased lymphocyte beta-adrenoreceptor function correlates with less agoraphobia and better outcome in panic disorder.

    abstract：:Previous studies have demonstrated reduced function of peripheral beta-adrenoreceptors in panic disorder with agoraphobia (PDA). We recently reported that decreased lymphocyte beta-receptor function was associated with milder agoraphobia and better treatment response in PDA. We now report on lymphocyte beta-receptor f...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/0165-0327(93)90115-z

    authors： Maddock RJ,Gietzen DW,Goodman TA

    更新日期：1993-09-01 00:00:00

  • A protocol for the Hamilton Rating Scale for Depression: Item scoring rules, Rater training, and outcome accuracy with data on its application in a clinical trial.

    abstract：BACKGROUND:We present a fully articulated protocol for the Hamilton Rating Scale for Depression (HAM-D), including item scoring rules, rater training procedures, and a data management algorithm to increase accuracy of scores prior to outcome analyses. The latter involves identifying potentially inaccurate scores as int...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2016.01.051

    authors： Rohan KJ,Rough JN,Evans M,Ho SY,Meyerhoff J,Roberts LM,Vacek PM

    更新日期：2016-08-01 00:00:00

  • Excessive daytime sleepiness in medical students of Hunan province: Prevalence, correlates, and its relationship with suicidal behaviors.

    abstract：BACKGROUND:Excessive daytime sleepiness (EDS) is common among medical students, but may have some serious consequences. This study aimed to investigate the prevalence and correlates of EDS among the medical students of Hunan Province, China. The correlation between EDS and suicidal ideation in our participants was also...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2019.05.036

    authors： Shen Y,Meng F,Tan SN,Zhang Y,Anderiescu EC,Abeysekera RE,Luo X,Zhang XY

    更新日期：2019-08-01 00:00:00

  • Piloting the 'Youth Early-intervention Study' ('YES'): Preliminary functional outcomes of a randomized controlled trial targeting social participation and physical well-being in young people with emerging mental disorders.

    abstract：INTRODUCTION:Young people with mental disorders present with diverse social, vocational, physical, and developmental needs. However, multifaceted interventions are rare. We examine the effectiveness of a clinical trial targeting social participation and physical well-being in young people accessing clinical services. ...

    journal_title：Journal of affective disorders

    pub_type： 杂志文章

    doi：10.1016/j.jad.2020.10.070

    authors： Gehue LJ,Crouse JJ,Battisti RA,Yim M,Carpenter JS,Scott EM,Hickie IB

    更新日期：2021-02-01 00:00:00