Abstract:
:We develop a numerical method for estimating optimal parameters in a mathematical model of the within-host dynamics of malaria infection. The model consists of a quasilinear system of partial differential equations. Convergence theory for the computed parameters is provided. Following this analysis, we present several numerical simulations that suggest that periodic treatments that are in synchronization with the periodic bursting rate of infected erythrocytes are the most productive strategies.
journal_name
Bull Math Bioljournal_title
Bulletin of mathematical biologyauthors
Thibodeaux JJ,Schlittenhardt TPdoi
10.1007/s11538-011-9650-8subject
Has Abstractpub_date
2011-11-01 00:00:00pages
2791-808issue
11eissn
0092-8240issn
1522-9602journal_volume
73pub_type
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