Mechanical Cell Competition in Heterogeneous Epithelial Tissues.

abstract：:To investigate morphogenesis and in particular circularization mechanisms in young mycelia, we observe cultures of the zygomycete Mucor spinosus and develop discrete models of two-dimensional filamental branching growth. The models are based on the hypothesis that the fungus secretes a regulatory substance that diffus...

journal_title：Bulletin of mathematical biology

authors： Indermitte C,Liebling M,Clémençon H

更新日期：1994-07-01 00:00:00

abstract：:It has been postulated that fibroblast growth factor (FGF) treatment of cultured limb bud mesenchyme cells reinforces the lateral inhibitory effect, but the cells also show accelerated pattern appearance. In the present study, we analyze how a small change in a specific parameter affects the speed of pattern appearanc...

journal_title：Bulletin of mathematical biology

authors： Miura T,Maini PK

更新日期：2004-07-01 00:00:00

abstract：:A model employing separate dose-dependent response functions for proliferation and differentiation of idiotypically interacting B cell clones is presented. For each clone the population dynamics of proliferating B cells, non-proliferating B cells and free antibodies are considered. An effective response function, whic...

journal_title：Bulletin of mathematical biology

authors： Sulzer B,van Hemmen JL,Neumann AU,Behn U

更新日期：1993-11-01 00:00:00

abstract：:The Hodgkin and Huxley equations have served as the benchmark model in electrophysiology since 1950s. But it suffers from four major drawbacks. Firstly, it is only phenomenological not mechanistic. Secondly, it fails to exhibit the all-or-nothing firing mechanism for action potential generation. Thirdly, it lacks a th...

journal_title：Bulletin of mathematical biology

authors： Deng B

更新日期：2017-06-01 00:00:00

abstract：:The mutation process is introduced into the colored coalescent theory. The mutation process can be viewed as an independent Poisson process running on the colored genealogical random tree generated by the colored coalescent process, with the edge lengths of the random tree serving as the time scale for the mutation pr...

journal_title：Bulletin of mathematical biology

authors： Tian JP,Lin XS

更新日期：2009-11-01 00:00:00

abstract：:A mathematical model (Kliemann, W. 1987. Bull. math. Biol. 49, 135-152.) that predicts the quantitative branching pattern of dendritic tree was evaluated using the apical and basal dendrites of rat hippocampal neurons. The Wald statistic for chi 2-test was developed for the branching pattern of dendritic trees and for...

journal_title：Bulletin of mathematical biology

authors： Carriquiry AL,Ireland WP,Kliemann W,Uemura E

更新日期：1991-01-01 00:00:00

abstract：:A system of differential equations for the control of tumor growth cells in a cycle nonspecific chemotherapy is analyzed. Spontaneously acquired drug resistance is taken into account, and a criterion for the selection of chemotherapeutic treatment is used. This criterion purports to describe the possibility of improve...

journal_title：Bulletin of mathematical biology

authors： Costa MI,Boldrini JL

更新日期：1997-03-01 00:00:00

abstract：:Bacillus subtilis cells may opt to forgo normal cell division and instead form spores if subjected to certain environmental stimuli, for example nutrient deficiency or extreme temperature. The resulting spores are extremely resilient and can survive for extensive periods of time, importantly under particularly harsh c...

journal_title：Bulletin of mathematical biology

authors： Jabbari S,Heap JT,King JR

更新日期：2011-01-01 00:00:00

abstract：:Microtubules (MTs) are protein filaments found in all eukaryotic cells which are crucial for many cellular processes including cell movement, cell differentiation, and cell division. Due to their role in cell division, they are often used as targets for chemotherapy drugs used in cancer treatment. Experimental studies...

journal_title：Bulletin of mathematical biology

authors： Honoré S,Hubert F,Tournus M,White D

更新日期：2019-03-01 00:00:00

abstract：:To analyze signals measured from human blood flow in the time-frequency domain, we used the wavelet transform which gives good time resolution for high-frequency components and good frequency resolution for low-frequency components. Five characteristic frequency peaks, corresponding to five almost periodic rhythmic ac...

journal_title：Bulletin of mathematical biology

authors： Bracic M,Stefanovska A

更新日期：1998-09-01 00:00:00

abstract：:A dynamic model for cell differentiation, where cells with internal chemical reaction dynamics interact with each other and replicate was studied. It led to spontaneous differentiation of cells and determination, as discussed in the isologous diversification. The following features of the differentiation were obtained...

journal_title：Bulletin of mathematical biology

authors： Furusawa C,Kaneko K

更新日期：1998-07-01 00:00:00

abstract：:Dispersal heterogeneity is increasingly being observed in ecological populations and has long been suspected as an explanation for observations of non-Gaussian dispersal. Recent empirical and theoretical studies have begun to confirm this. Using an integro-difference model, we allow an individual's diffusivity to be d...

journal_title：Bulletin of mathematical biology

authors： Stover JP,Kendall BE,Nisbet RM

更新日期：2014-11-01 00:00:00

abstract：:A model of embryo energetics was fitted to data from the literature for species as different as snails and mammals. The model is based on assumptions about energy uptake, storage and utilization. It describes the animal by two state variables: volume and energy storage. Embryo weight is taken to be proportional to vol...

journal_title：Bulletin of mathematical biology

authors： Zonneveld C,Kooijman SA

更新日期：1993-05-01 00:00:00

abstract：:We develop a theory for host seeking decisions in mosquitoes that explicitly considers the tradeoffs mosquitoes face in allocation to somatic and gametic function. Specifically, we consider conditions under which mosquitoes should seek out nectar and blood hosts upon encountering host odours. Results from development ...

journal_title：Bulletin of mathematical biology

authors： Roitberg BD,Friend WG

更新日期：1992-03-01 00:00:00

abstract：:Pseudomonas aeruginosa is a Gram-negative bacterium that is responsible for a wide range of infections in humans. Colonies employ quorum sensing (QS) to coordinate gene expression, including for virulence factors, swarming motility and complex social traits. The QS signalling system of P. aeruginosa is known to involv...

journal_title：Bulletin of mathematical biology

authors： Alfiniyah C,Bees MA,Wood AJ

更新日期：2017-06-01 00:00:00

abstract：:Aggregation of membrane molecules is a crucial phenomenon in developing organisms, a classic example being the aggregation of post-synaptic receptors during synaptogenesis. Our understanding of the molecular events involved is improving, but most models of the aggregation or concentration process do not address bindin...

journal_title：Bulletin of mathematical biology

authors： Stollberg J

更新日期：1995-09-01 00:00:00

abstract：:We introduce a mesoscopic scale chemotaxis model for traveling wave phenomena which is induced by food metric. The organisms of this simplified kinetic model have two discrete velocity modes, [Formula: see text] and a constant tumbling rate. The main feature of the model is that the speed of organisms is constant [For...

journal_title：Bulletin of mathematical biology

authors： Choi SH,Kim YJ

更新日期：2017-02-01 00:00:00

abstract：:Chemical reactions are discrete, stochastic events. As such, the species' molecular numbers can be described by an associated master equation. However, handling such an equation may become difficult due to the large size of reaction networks. A commonly used approach to forecast the behaviour of reaction networks is t...

journal_title：Bulletin of mathematical biology

authors： López-Caamal F,Marquez-Lago TT

更新日期：2014-09-01 00:00:00

abstract：:The accuracy of the Fitch method for reconstructing ancestral states on ultrametric phylogenetic trees is studied. Two recurrence relations for computing the accuracy are given here. Using these relations, we analyze the convergence of the accuracy of the Fitch method for reconstructing the root state on a complete bi...

journal_title：Bulletin of mathematical biology

authors： Zhang L,Shen J,Yang J,Li G

更新日期：2010-10-01 00:00:00

abstract：:Understanding the life-history complex of eusociality has remained an enduring problem in evolutionary ecology, partially because natural selection models have considered traits in relative isolation. I aim for a more inclusive model that uses ecological interactions to predict the evolutionary existence of sexual rep...

journal_title：Bulletin of mathematical biology

authors： Witting L

更新日期：2007-05-01 00:00:00

abstract：:In Xenopus and Drosophila, the nucleocytoplasmic ratio controls many aspects of cell-cycle remodeling during the transitory period that leads from fast and synchronous cell divisions of early development to the slow, carefully regulated growth and divisions of somatic cells. After the fifth cleavage in sea urchin embr...

journal_title：Bulletin of mathematical biology

authors： Ciliberto A,Tyson JJ

更新日期：2000-01-01 00:00:00

abstract：:Knowledge about large-scale and long-term dynamics of (natural) populations is required to assess the efficiency of control strategies, the potential for long-term persistence, and the adaptability to global changes such as habitat fragmentation and global warming. For most natural populations, such as pest population...

journal_title：Bulletin of mathematical biology

authors： Soubeyrand S,Neuvonen S,Penttinen A

更新日期：2009-02-01 00:00:00

abstract：:A model, based on the principles of continuum mechanics, is presented for the analysis of cell-velocity fields within wool follicles. The model requires specification of three follicle characteristics in the form of spatially varying fields: viscosity, cell density and cell production rate. The viscosity is introduced...

journal_title：Bulletin of mathematical biology

authors： Louie K,Hall AJ,Gandar PW

更新日期：1998-01-01 00:00:00

abstract：:Two algorithms for the efficient identification of segment neighborhoods are presented. A segment neighborhood is a set of contiguous residues that share common features. Two procedures are developed to efficiently find estimates for the parameters of the model that describe these features and for the residues that de...

journal_title：Bulletin of mathematical biology

authors： Auger IE,Lawrence CE

更新日期：1989-01-01 00:00:00

abstract：:We present a new symmetric model of the idiotypic immune network. The model specifies clones of B-lymphocytes and incorporates: (1) influx and decay of cells; (2) symmetric stimulatory and inhibitory idiotypic interactions; (3) an explicit affinity parameter (matrix); (4) external (i.e. non-idiotypic) antigens. Suppre...

journal_title：Bulletin of mathematical biology

authors： De Boer RJ,Hogeweg P

更新日期：1989-01-01 00:00:00

abstract：:Marine birds and mammals move between various habitats during the day as they engage in behaviors related to resting, sleeping, preening, feeding, and breeding. The per capita rates of movement between these habitats, and hence the habitat occupancy dynamics, often are functions of environmental variables such as tide...

journal_title：Bulletin of mathematical biology

authors： Henson SM,Hayward JL,Damania SP

更新日期：2006-02-01 00:00:00

abstract：:Evolutionary game dynamics of two strategies in finite population is studied by continuous probabilistic approach. Besides frequency dependent selection, mutation was also included in this study. The equilibrium probability density functions of abundance, expected time to extinction or fixation were derived and their ...

journal_title：Bulletin of mathematical biology

authors： Gao M

更新日期：2009-07-01 00:00:00

abstract：:Cancer is a complex phenomenon, and the sheer variation in behaviour across different types renders it difficult to ascertain underlying biological mechanisms. Experimental approaches frequently yield conflicting results for myriad reasons, and mathematical modelling of cancer is a vital tool to explore what we cannot...

journal_title：Bulletin of mathematical biology

authors： Grimes DR,Fletcher AG

更新日期：2020-01-22 00:00:00

abstract：:A mathematical model is presented for the steps in the elongation process, and the steady-state elongation rate as a function of the amino acid concentrations is found. In addition, the reset sub-process of the elongation process is modeled. The rate of elongation of peptide chains is found to be a function of the con...

journal_title：Bulletin of mathematical biology

authors： Heyd A,Drew DA

更新日期：2003-11-01 00:00:00

abstract：:Bacterial quorum sensing (QS) is a form of intercellular communication that relies on the production and detection of diffusive signaling molecules called autoinducers. Such a mechanism allows the bacteria to track their cell density in order to regulate group behavior, such as biofilm formation and bioluminescence. I...

journal_title：Bulletin of mathematical biology

authors： Fan G,Bressloff PC

更新日期：2019-05-01 00:00:00