Aleutian disease parvovirus infection of mink and ferrets elicits an antibody response to a second nonstructural viral protein.

abstract：:Despite differences in the pathogenesis and host range of alphaherpesviruses, many stages of their morphogenesis are thought to be conserved. Here, an ultrastructural study of bovine herpesvirus 1 (BoHV-1) envelopment revealed profiles similar to those previously found for herpes simplex virus 1 (HSV-1), with BoHV-1 c...

journal_title：Journal of virology

authors： Russell T,Bleasdale B,Hollinshead M,Elliott G

更新日期：2018-10-29 00:00:00

abstract：:Moloney murine leukemia virus (M-MuLV) is capable of inducing promonocytic leukemia in 50% of adult BALB/c mice that have received peritoneal injections of pristane, but Friend MuLV strain 57 (F-MuLV) is nonleukemogenic under similar conditions. It was shown earlier that these differences could not be mapped to the U3...

journal_title：Journal of virology

authors： Mukhopadhyaya R,Richardson J,Nazarov V,Corbin A,Koller R,Sitbon M,Wolff L

更新日期：1994-08-01 00:00:00

abstract：:Cytotoxic T lymphocyte (CTL) activity was assessed in mice immunized with DNA plasmids containing the human immunodeficiency virus type 1 (HIV-1) gp120 envelope (pTMIgp120) or p55gag (pTMIgag) gene regulated by the bacteriophage T7 promoter. Immunization with either plasmid resulted in CTL activity against class I maj...

journal_title：Journal of virology

authors： Selby MJ,Doe B,Walker CM

更新日期：1997-10-01 00:00:00

abstract：:Murine gammaherpesvirus 68 (MHV68) infection of mice provides a tractable small-animal system for assessing viral requirements for establishment of and reactivation from latency. The M2 gene product has no homology to any known proteins but has been shown to play a role in both the establishment of MHV68 latency and r...

journal_title：Journal of virology

authors： DeZalia M,Speck SH

更新日期：2008-08-01 00:00:00

abstract：:Infectious cDNA clones of mild (CHV1-Euro7) and severe (CHV1-EP713) hypovirus strains responsible for virulence attenuation (hypovirulence) of the chestnut blight fungus Cryphonectria parasitica were used to construct viable chimeric viruses. Differences in virus-mediated alterations of fungal colony morphology, growt...

journal_title：Journal of virology

authors： Chen B,Geletka LM,Nuss DL

更新日期：2000-08-01 00:00:00

abstract：:The mechanism of cellular src (c-src) transduction by a transformation-defective deletion mutant, td109, of Rous sarcoma virus was studied by sequence analysis of the recombinational junctions in three td109-derived recovered sarcoma viruses (rASVs). Our results show that two rASVs have been generated by recombination...

journal_title：Journal of virology

authors： Soong MM,Iijima S,Wang LH

更新日期：1986-09-01 00:00:00

abstract：:Extracts from nodavirus-infected Drosophila cells contained detergent-labile 140S "young" particles much richer than mature virions in their content of protein alpha, a precursor of coat proteins beta and gamma. Incorporation studies in infected cells showed that most newly synthesized alpha protein was assembled into...

journal_title：Journal of virology

authors： Gallagher TM,Rueckert RR

更新日期：1988-09-01 00:00:00

abstract：:Previous findings of low levels of reverse transcriptase (RT) activity in chick cell-derived measles and mumps vaccines showed this activity to be associated with virus particles containing RNA of both subgroup E endogenous avian leukosis viruses (ALV-E) and endogenous avian viruses (EAV). These particles originate fr...

journal_title：Journal of virology

authors： Johnson JA,Heneine W

更新日期：2001-04-01 00:00:00

abstract：:The St-1 genome is about 6,050 base pairs in size, approximately 10% larger than phiX174 (5,375 base pairs). The DNA fragments obtained by HincII, HaeIII, and EcoRI digestion were ordered and aligned into a colinear map, and the single BglI cleavage site was located. ...

journal_title：Journal of virology

authors： Grindley JN,Godson GN

更新日期：1978-09-01 00:00:00

abstract：:RNA transfer (Northern) blot analysis was used to perform the physical characterization of the transcript expressed in murine sensory nerve ganglia latently infected with herpes simplex virus type 1. Most of this latency-associated transcript (LAT) was isolated in the poly(A)- fraction from ganglia. A smaller RNA spec...

journal_title：Journal of virology

authors： Wagner EK,Devi-Rao G,Feldman LT,Dobson AT,Zhang YF,Flanagan WM,Stevens JG

更新日期：1988-04-01 00:00:00

abstract：:We compared the proteins which associate with middle T antigen (MT) of polyomavirus in human cells infected with Ad5(pymT), a recombinant adenovirus which directs the overexpression of MT, with the MT-associated proteins (MTAPs) previously identified in murine fibroblasts expressing MT. MTAPs of 27, 29, 36, and 63 kil...

journal_title：Journal of virology

authors： Pallas DC,Morgan W,Roberts TM

更新日期：1989-11-01 00:00:00

abstract：:Bicistronic RNAs containing the 373-nucleotide-long 5' nontranslated region (NTR) of the classical swine fever virus (CSFV) genome as intercistronic spacer were used to show the presence of an internal ribosome entry site (IRES) in the 5' end of the CSFV genome. By coexpression of the poliovirus 2A protease it was dem...

journal_title：Journal of virology

authors： Rijnbrand R,van der Straaten T,van Rijn PA,Spaan WJ,Bredenbeek PJ

更新日期：1997-01-01 00:00:00

abstract：:The small-ruminant lentiviruses ovine maedi-visna virus (MVV) and caprine arthritis-encephalitis virus (CAEV) cause encephalitis, progressive pneumonia, arthritis, and mastitis in sheep and goats. Icelandic MVV strains, which are lytic in tissue culture, have a wide species distribution of functional receptors, which ...

journal_title：Journal of virology

authors： Hötzel I,Cheevers WP

更新日期：2001-08-01 00:00:00

abstract：:Diverse members of the Paramyxovirus family of negative-strand RNA viruses effectively suppress host innate immune responses through the actions of their V proteins. The V protein mediates interference with the interferon regulatory RNA helicase MDA5 to avoid cellular antiviral responses. Analysis of the interaction i...

journal_title：Journal of virology

authors： Parisien JP,Bamming D,Komuro A,Ramachandran A,Rodriguez JJ,Barber G,Wojahn RD,Horvath CM

更新日期：2009-07-01 00:00:00

abstract：:There is controversy as to whether the cell entry mechanism of Sindbis virus (SIN) involves direct fusion of the viral envelope with the plasma membrane at neutral pH or uptake by receptor-mediated endocytosis and subsequent low-pH-induced fusion from within acidic endosomes. Here, we studied the membrane fusion activ...

journal_title：Journal of virology

authors： Smit JM,Bittman R,Wilschut J

更新日期：1999-10-01 00:00:00

abstract：:The nucleic acids of influenza A, B, and C viruses were compared. Susceptibility to nucleases demonstrates that influenza C virus, just as influenza A and B viruses, possesses single-stranded RNA as its genome. The base compositions of the RNAs of influenza A, B, and influenza C virus are almost identical and comparat...

journal_title：Journal of virology

authors： Ritchey MB,Palese P,Kilbourne ED

更新日期：1976-05-01 00:00:00

abstract：UNLABELLED:The APOBEC3 family of DNA cytosine deaminases has important roles in innate immunity and cancer. It is unclear how DNA tumor viruses regulate these enzymes and how these interactions, in turn, impact the integrity of both the viral and cellular genomes. Polyomavirus (PyVs) are small DNA pathogens that contai...

journal_title：Journal of virology

authors： Verhalen B,Starrett GJ,Harris RS,Jiang M

更新日期：2016-06-24 00:00:00

abstract：:The hepatitis B virus X protein (HBX) is essential for the establishment of HBV infection in vivo and exerts a pleiotropic effect on diverse cellular functions. The yeast two-hybrid system had indicated that HBX could interact with two subunits of the 26S proteasome. Here we demonstrate an association in vivo of HBX w...

journal_title：Journal of virology

authors： Hu Z,Zhang Z,Doo E,Coux O,Goldberg AL,Liang TJ

更新日期：1999-09-01 00:00:00

abstract：:In this report, we describe the isolation, molecular genetic mapping, and phenotypic characterization of vaccinia virus mutants resistant to cytosine arabinoside (araC) and phosphonoacetic acid (PAA). At 37 degrees C, 8 microM araC was found to prevent macroscopic plaque formation by wild-type virus and to cause a 10(...

journal_title：Journal of virology

authors： Taddie JA,Traktman P

更新日期：1993-07-01 00:00:00

abstract：:Type I interferon (IFN-I) inhibits the replication of different viruses. However, the effect of IFN-I on the human T-lymphotropic virus type 1 (HTLV-1) viral cycle is controversial. Here, we investigated the consequences of IFN-α addition for different steps of HTLV-1 and HTLV-2 infection. We first show that alpha int...

journal_title：Journal of virology

authors： Cachat A,Chevalier SA,Alais S,Ko NL,Ratner L,Journo C,Dutartre H,Mahieux R

更新日期：2013-12-01 00:00:00

abstract：:Prestimulation of the TLR4 pathway with lipopolysaccharide (LPS) protects mice from lethal infection with H5N1 influenza virus. Here, we reveal that the TLR4-TRIF pathway is required for this protective effect by using mice whose TLR4-related molecules were knocked out. Microarray analysis of primary mouse lung cultur...

journal_title：Journal of virology

authors： Shinya K,Ito M,Makino A,Tanaka M,Miyake K,Eisfeld AJ,Kawaoka Y

更新日期：2012-01-01 00:00:00

abstract：:The replication of porcine circovirus type 1 (PCV1) is thought to occur by rolling-circle replication (RCR), whereby the introduction of a single-strand break generates a free 3'-hydroxyl group serving as a primer for subsequent DNA synthesis. The covalently closed, single-stranded genome of PCV1 replicates via a doub...

journal_title：Journal of virology

authors： Steinfeldt T,Finsterbusch T,Mankertz A

更新日期：2006-07-01 00:00:00

abstract：:We previously reported that a mutant Rous sarcoma virus (RSV) with an alternate polypurine tract (PPT), DuckHepBFlipPPT, had unexpectedly high titers and that the PPT was miscleaved primarily at one position following a GA dinucleotide by the RNase H of reverse transcriptase (RT). This miscleavage resulted in a portio...

journal_title：Journal of virology

authors： Chang KW,Oh J,Alvord WG,Hughes SH

更新日期：2008-09-01 00:00:00

abstract：:Respiratory syncytial virus (RSV) infection causes substantial morbidity and some deaths in the young and elderly worldwide. There is no safe and effective vaccine available, although it is possible to reduce the hospitalization rate for high-risk children by anti-RSV antibody prophylaxis. RSV has been shown to modify...

journal_title：Journal of virology

authors： Zhang W,Choi Y,Haynes LM,Harcourt JL,Anderson LJ,Jones LP,Tripp RA

更新日期：2010-01-01 00:00:00

abstract：UNLABELLED:The accessory gene vpr, common to all primate lentiviruses, induces potent G2/M arrest in cycling cells. A recent study showed that human immunodeficiency virus type 1 (HIV-1) viral protein R (Vpr) mediates this through activation of the SLX4/MUS81/EME1 exonuclease complex that forms part of the Fanconi anem...

journal_title：Journal of virology

authors： Berger G,Lawrence M,Hué S,Neil SJ

更新日期：2015-01-01 00:00:00

abstract：:The 5'-untranslated regions (5' UTRs) of picornavirus genomes contain an internal ribosomal entry site (IRES) that promotes the end-independent initiation of translation. Picornavirus IRESs are classified into four structurally distinct groups, each with different initiation factor requirements. Here, we identify a fi...

journal_title：Journal of virology

authors： Sweeney TR,Dhote V,Yu Y,Hellen CU

更新日期：2012-02-01 00:00:00

abstract：:We have devised an enrichment scheme for the isolation of export-competent derivatives of pseudorabies virus glycoprotein gIII signal peptide mutants. Enrichment is based upon a growth advantage imparted upon gIII-containing virions compared with virions lacking the glycoprotein. Each of identified derivatives suppres...

journal_title：Journal of virology

authors： Powers L,Ryan P

更新日期：1994-05-01 00:00:00

abstract：:A panel of 28 insertion mutants of the human immunodeficiency virus type 1 (HIV-1) Gag precursor (Pr55Gag) was constructed by linker-insertion mutagenesis and expressed in recombinant baculovirus-infected insect cells. One set of 14 mutants carried the normal N-myristylation signal; the other set constituted their non...

journal_title：Journal of virology

authors： Chazal N,Carrière C,Gay B,Boulanger P

更新日期：1994-01-01 00:00:00

abstract：:Individuals infected with the human immunodeficiency virus (HIV) experience a marked loss of CD4+ T lymphocytes, leading to fatal immunodeficiency. The mechanisms causing the depletion of these cells are not yet understood. In this study, we observed that CD4+ T lymphocytes from HIV type 1 (HIV-1)-infected and uninfec...

journal_title：Journal of virology

authors： Heinkelein M,Sopper S,Jassoy C

更新日期：1995-11-01 00:00:00

abstract：:Epstein-Barr virus (EBV) nuclear antigen 2 (EBNA-2) is a key determinant in the EBV-driven B-cell growth transformation process. By activating an array of viral and cellular target genes, EBNA-2 initiates a cascade of events which ultimately cause cell cycle entry and the proliferation of the infected B cell. In order...

journal_title：Journal of virology

authors： Maier S,Staffler G,Hartmann A,Höck J,Henning K,Grabusic K,Mailhammer R,Hoffmann R,Wilmanns M,Lang R,Mages J,Kempkes B

更新日期：2006-10-01 00:00:00