Host range of small-ruminant lentivirus cytopathic variants determined with a selectable caprine arthritis- encephalitis virus pseudotype system.

abstract：:During the 2009 H1N1 influenza virus pandemic (pdmH1N1) outbreak, it was found that most individuals lacked antibodies against the new pdmH1N1 virus, and only the elderly showed anti-hemagglutinin (anti-HA) antibodies that were cross-reactive with the new strains. Different studies have demonstrated that prior contact...

journal_title：Journal of virology

authors： Fang Y,Banner D,Kelvin AA,Huang SS,Paige CJ,Corfe SA,Kane KP,Bleackley RC,Rowe T,Leon AJ,Kelvin DJ

更新日期：2012-02-01 00:00:00

abstract：:The herpes simplex virus (HSV) virion host shutoff (vhs) protein (UL41 gene product) is a component of the HSV virion tegument that triggers shutoff of host protein synthesis and accelerated mRNA degradation during the early stages of HSV infection. vhs displays weak amino acid sequence similarity to the fen-1 family ...

journal_title：Journal of virology

authors： Elgadi MM,Smiley JR

更新日期：1999-11-01 00:00:00

abstract：:Incorporation of the vaccinia virus A36R protein into the outer membrane of intracellular enveloped virions (IEV) is dependent on expression of the A33R protein. Possible interactions of the 200-amino-acid cytoplasmic domain of the A36R protein with itself or with the cytoplasmic domain of the A33R, A34R, B5R, or F12L...

journal_title：Journal of virology

authors： Ward BM,Weisberg AS,Moss B

更新日期：2003-04-01 00:00:00

abstract：:Two live attenuated single-deletion mutant simian immunodeficiency virus (SIV) constructs, SIV239Deltanef and SIVPBj6.6Deltanef, were tested for their abilities to stimulate protective immunity in macaques. During the immunization period the animals were examined for specific immune responses and virus growth. Each co...

journal_title：Journal of virology

authors： Lewis MG,Yalley-Ogunro J,Greenhouse JJ,Brennan TP,Jiang JB,VanCott TC,Lu Y,Eddy GA,Birx DL

更新日期：1999-02-01 00:00:00

abstract：UNLABELLED:Avian metapneumovirus (aMPV), also known as avian pneumovirus or turkey rhinotracheitis virus, is the causative agent of turkey rhinotracheitis and is associated with swollen head syndrome in chickens. Since its discovery in the 1970s, aMPV has been recognized as an economically important pathogen in the pou...

journal_title：Journal of virology

authors： Sun J,Wei Y,Rauf A,Zhang Y,Ma Y,Zhang X,Shilo K,Yu Q,Saif YM,Lu X,Yu L,Li J

更新日期：2014-11-01 00:00:00

abstract：:A detailed kinetic and quantitative analysis of the early and late biosynthetic events undergone by the human immunodeficiency virus type 1 envelope protein expressed by a recombinant vaccinia virus was performed. Early folding events that occurred in the endoplasmic reticulum included disulfide bond formation (t1/2 a...

journal_title：Journal of virology

authors： Earl PL,Moss B,Doms RW

更新日期：1991-04-01 00:00:00

abstract：:MC159 is a viral FLIP (FLICE inhibitory protein) encoded by the molluscum contagiosum virus (MCV) enabling MCV to evade antiviral immunity and to establish persistent infections in humans. Here, we show that MC159 contains a functional SH3 binding motif, which mediates avid and selective binding to SH3BP4, a signaling...

journal_title：Journal of virology

authors： Schmotz C,Uğurlu H,Vilen S,Shrestha S,Fagerlund R,Saksela K

更新日期：2019-05-01 00:00:00

abstract：:A phage, designated CP-51, that carries out generalized transduction in Bacillus cereus 569 was isolated from soil. All auxotrophic mutants tested, those requiring tryptophan, histidine, leucine, isoleucine, methionine, or phenylalanine, were transduced to prototrophy. The phage was extremely unstable when stored at 2...

journal_title：Journal of virology

authors： Thorne CB

更新日期：1968-07-01 00:00:00

abstract：:Rhesus monkey rhadinovirus (RRV), a simian gamma-2 herpesvirus closely related to the Kaposi sarcoma-associated herpesvirus, replicates lytically in cultured rhesus monkey fibroblasts and establishes persistence in B cells. Overlapping cosmid clones were generated that encompass the entire 130-kilobase-pair genome of ...

journal_title：Journal of virology

authors： Bilello JP,Morgan JS,Damania B,Lang SM,Desrosiers RC

更新日期：2006-02-01 00:00:00

abstract：:Proteolytic processing of the dengue virus polyprotein is mediated by host cell proteases and the virus-encoded NS2B-NS3 two-component protease. The NS3 protease represents an attractive target for the development of antiviral inhibitors. The three-dimensional structure of the NS3 protease domain has been determined, ...

journal_title：Journal of virology

authors： Niyomrattanakit P,Winoyanuwattikun P,Chanprapaph S,Angsuthanasombat C,Panyim S,Katzenmeier G

更新日期：2004-12-01 00:00:00

abstract：:To assess the possible contribution of host immune responses to the exertion of Fv2-associated resistance to Friend virus (FV)-induced disease development, we inoculated C57BL/6 (B6) mice that lacked various subsets of lymphocytes with FV containing no lactate dehydrogenase-elevating virus. Fv2(r) B6 mice lacking CD4(...

journal_title：Journal of virology

authors： Tsuji-Kawahara S,Kawabata H,Matsukuma H,Kinoshita S,Chikaishi T,Sakamoto M,Kawasaki Y,Miyazawa M

更新日期：2013-12-01 00:00:00

abstract：UNLABELLED:HIV-1 Vpu decreases the exposure of epitopes within the viral envelope glycoprotein (Env) on the surface of infected cells by downregulating both BST2 and CD4. To test the hypothesis that inhibiting Vpu activity would increase the exposure of these epitopes and sensitize infected cells to antibody-dependent ...

journal_title：Journal of virology

authors： Tokarev A,Stoneham C,Lewinski MK,Mukim A,Deshmukh S,Vollbrecht T,Spina CA,Guatelli J

更新日期：2015-12-16 00:00:00

abstract：:The cytolytic T-lymphocyte (CTL) response to respiratory infection with equine herpesvirus 1 (EHV-1) in CBA (H-2(k)) mice was investigated. Intranasal (i.n.) inoculation of mice with the attenuated EHV-1 strain KyA resulted in the generation of a primary virus-specific CTL response in the draining mediastinal lymph no...

journal_title：Journal of virology

authors： Smith PM,Zhang Y,Jennings SR,O'Callaghan DJ

更新日期：1998-07-01 00:00:00

abstract：:The virion proteins encoded by the avian retroviral pol gene (reverse transcriptase and endonuclease) are formed by the proteolytic processing of a gag-pol fusion protein precursor. Recent studies have predicted that the avian sarcoma-leukosis virus pol precursor protein undergoes a previously undetected processing ev...

journal_title：Journal of virology

authors： Katz RA,Skalka AM

更新日期：1988-02-01 00:00:00

abstract：:The human foamy virus (HFV) contains within the U3 region of its long terminal repeat (LTR) three perfect consensus sequences for the binding of the inducible transcription factor AP-1. Results of DNase I footprint protection and gel retardation assays demonstrated that proteins in extracts of HeLa and BHK-21 cells as...

journal_title：Journal of virology

authors： Maurer B,Serfling E,ter Meulen V,Rethwilm A

更新日期：1991-11-01 00:00:00

abstract：:Previous studies have demonstrated that the genetic determinants of simian immunodeficiency virus (SIV) neurovirulence map to the env and nef genes. Recent studies from our laboratory demonstrated that SIV replication in primary rhesus macaque astrocyte cultures is dependent upon the nef gene. Here, we demonstrate tha...

journal_title：Journal of virology

authors： Overholser ED,Babas T,Zink MC,Barber SA,Clements JE

更新日期：2005-04-01 00:00:00

abstract：:We characterized the cellular immune response to severe acute respiratory syndrome coronavirus (SARS-CoV) infection in 12- to 14-month-old BALB/c mice, a model that mimics features of the human disease. Following intranasal administration, the virus replicated in the lungs, with peak titers on day 2 postinfection. Enh...

journal_title：Journal of virology

authors： Chen J,Lau YF,Lamirande EW,Paddock CD,Bartlett JH,Zaki SR,Subbarao K

更新日期：2010-02-01 00:00:00

abstract：:The high diversity of HLA binding preferences has been driven by the sequence diversity of short segments of relevant pathogenic proteins presented by HLA molecules to the immune system. To identify possible commonalities in HLA binding preferences, we quantify these using a novel measure termed "targeting efficiency,...

journal_title：Journal of virology

authors： Hertz T,Nolan D,James I,John M,Gaudieri S,Phillips E,Huang JC,Riadi G,Mallal S,Jojic N

更新日期：2011-02-01 00:00:00

abstract：UNLABELLED:Infection of the lower respiratory tract by influenza A viruses results in increases in inflammation and immune cell infiltration in the lung. The dynamic relationships among the lung microenvironments, the lung, and systemic host responses during infection remain poorly understood. Here we used extensive sy...

journal_title：Journal of virology

authors： Camp JV,Bagci U,Chu YK,Squier B,Fraig M,Uriarte SM,Guo H,Mollura DJ,Jonsson CB

更新日期：2015-09-01 00:00:00

abstract：:Chimeric bovine respiratory syncytial viruses (BRSV) expressing glycoproteins of bovine parainfluenza virus type 3 (BPIV-3) instead of BRSV glycoproteins were generated from cDNA. In the BRSV antigenome cDNA, the open reading frames of the major BRSV glycoproteins, attachment protein G and fusion protein F, were repla...

journal_title：Journal of virology

authors： Stope MB,Karger A,Schmidt U,Buchholz UJ

更新日期：2001-10-01 00:00:00

abstract：:The retrovirus type B leukemogenic virus (TBLV) causes T-cell lymphomas in mice. We have identified the Rorgamma locus as an integration site in 19% of TBLV-induced tumors. Overexpression of one or more Rorgamma isoforms in >77% of the tumors tested may complement apoptotic effects of c-myc overexpression. ...

journal_title：Journal of virology

authors： Broussard DR,Lozano MM,Dudley JP

更新日期：2004-05-01 00:00:00

abstract：:Human hepatitis B virus (HBV) is a small DNA virus that replicates inside the viral nucleocapsid by reverse transcription of an RNA intermediate. Encapsidation of this RNA pregenome is mediated by the interaction of the viral replication enzyme P with the structured 5'-proximal RNA element epsilon; replication was tho...

journal_title：Journal of virology

authors： Nassal M,Rieger A

更新日期：1996-05-01 00:00:00

abstract：:Fusion of the membrane of the Moloney murine leukemia virus (Mo-MLV) Env protein is facilitated by cleavage of the R peptide from the cytoplasmic tail of its TM subunit, but the mechanism for this effect has remained obscure. The fusion is also controlled by the isomerization of the intersubunit disulfide of the Env S...

journal_title：Journal of virology

authors： Löving R,Li K,Wallin M,Sjöberg M,Garoff H

更新日期：2008-03-01 00:00:00

abstract：:Epstein-Barr virus (EBV) is associated with about 6 to 16% of gastric carcinoma cases worldwide. Expression of the EBV microRNAs (miRNAs) was observed in B cells and nasopharyngeal carcinoma cells infected with EBV. However, it is not clear if the EBV miRNAs are expressed in EBV-associated gastric carcinomas (EBVaGCs)...

journal_title：Journal of virology

authors： Kim DN,Chae HS,Oh ST,Kang JH,Park CH,Park WS,Takada K,Lee JM,Lee WK,Lee SK

更新日期：2007-01-01 00:00:00

abstract：:Rous sarcoma virus (RSV), a simple retrovirus, needs to export unspliced viral RNA from the nucleus to the cytoplasm, circumventing the host cell restriction on cytoplasmic expression of intron-containing RNA. The cytoplasmic accumulation of full-length viral RNA is promoted by two cis-acting direct repeat (DR) elemen...

journal_title：Journal of virology

authors： Paca RE,Ogert RA,Hibbert CS,Izaurralde E,Beemon KL

更新日期：2000-10-01 00:00:00

abstract：:The sequence of the S RNA of La Crosse bunyavirus was deduced from analyses of DNA copies cloned in the Escherichia coli plasmid pBR322. The S RNA is 984 nucleotides in length, has a base ratio of 31.8% U, 27.0% A, 23.2% C, and 18.0% G, and codes for two distinct gene products that are read from overlapping reading fr...

journal_title：Journal of virology

authors： Akashi H,Bishop DH

更新日期：1983-03-01 00:00:00

abstract：:Gammaherpesvirus 68 (gammaHV68, or MHV68) is a naturally occurring rodent pathogen that replicates to high titer in cell culture and is amenable to in vivo experimental evaluation of viral and host determinants of gammaherpesvirus disease. However, the inability of MHV68 to transform primary murine B cells in culture,...

journal_title：Journal of virology

authors： Forrest JC,Speck SH

更新日期：2008-08-01 00:00:00

abstract：:Human metapneumovirus (hMPV) is a recently discovered paramyxovirus that is a major cause of lower-respiratory-tract disease. hMPV is associated with more severe disease in infants and persons with underlying medical conditions. Animal studies have shown that the hMPV fusion (F) protein alone is capable of inducing pr...

journal_title：Journal of virology

authors： Williams JV,Chen Z,Cseke G,Wright DW,Keefer CJ,Tollefson SJ,Hessell A,Podsiad A,Shepherd BE,Sanna PP,Burton DR,Crowe JE Jr,Williamson RA

更新日期：2007-08-01 00:00:00

abstract：:TRIM5α is a natural resistance factor that binds retroviral capsid proteins and restricts virus replication. The B30.2/SPRY domain of TRIM5α is polymorphic in rhesus macaques, and some alleles are associated with reduced simian immunodeficiency virus (SIV) SIV(mac251) and SIV(smE543) replication in vivo. We determined...

journal_title：Journal of virology

authors： Fenizia C,Keele BF,Nichols D,Cornara S,Binello N,Vaccari M,Pegu P,Robert-Guroff M,Ma ZM,Miller CJ,Venzon D,Hirsch V,Franchini G

更新日期：2011-12-01 00:00:00

abstract：:The small RNA segment (S segment) of Uukuniemi (UUK) virus encodes two proteins, the nucleocapsid protein (N) and a nonstructural protein (NSs), by an ambisense strategy. The function of NSs has not been elucidated for any of the bunyaviruses expressing this protein. We have now expressed the N and NSs proteins in Sf9...

journal_title：Journal of virology

authors： Simons JF,Persson R,Pettersson RF

更新日期：1992-07-01 00:00:00