Abstract:
OBJECTIVE:The aim of this study was to investigate the age-related changes in the articular disc, condyle, condylar fibrocartilage, and subchondral bone of the temporomandibular joint (TMJ) in rabbits. METHODS:Female New Zealand white rabbit aged 1, 4, 12, and 32 weeks were obtained. Each age group comprised 5 rabbits and was subjected to chondrocyte culture, histological assessment of the articular disc length, assessment of the anteroposterior diameter of the condyle, measurement of the fibrocartilage thickness, and assessment of the subchondral bone architecture. The production of Collagen, type II, alpha1 (COL2A1); SOX9; Collagen, type X, alpha1 (COL10A1); and Runt-related transcription factor 2 (Runx2) was detected via western blot. Six rabbits at the ages of 12 and 32 weeks were sacrificed for the mechanical pressure loading test (75 kPa, 3 days). Changes in the condyles after pressurization were observed via scanning electron microscopy and evaluated by micro-CT. RESULTS:Significant enlargement of the condyle occurred from 4 to 12 weeks of age (p = 0.003); however, the length of the articular disc increased significantly from 1 to 12 weeks of age (p < 0.005). A rapid decrease in the cartilage thickness but an increase in the subchondral bone density occurred from 1 to 4 weeks of age and from 4 to 32 weeks of age in rabbit, respectively (p < 0.05). The expressions of COL2A1 and SOX9 gradually decreased from 1 to 32 weeks of age. The protein expressions of COL10A1 and Runx2 were maintained at a high level at 4-12 weeks of age. After static mechanical pressure loading, the damage and reduction in the bone mineral density (BMD) in the12-week-old group was greater than those in the 32-week-old group. CONCLUSIONS:An inconsistency between the condyle and articular disc during growth and development may be a causal factor for temporomandibular disorders TMDs in adolescents. Our findings suggest that the response of the adult condyle to the mechanical pressure is significantly greater than that of the adolescent condyle; however, with regard to reconstruction, the situation is reversed, which may influence the pathological progress of TMDs.
journal_name
Arch Oral Bioljournal_title
Archives of oral biologyauthors
Huang L,Zhang L,Li H,Yan J,Xu X,Cai Xdoi
10.1016/j.archoralbio.2019.104639subject
Has Abstractpub_date
2020-03-01 00:00:00pages
104639eissn
0003-9969issn
1879-1506pii
S0003-9969(19)30606-5journal_volume
111pub_type
杂志文章abstract:OBJECTIVE:Gingival fibroblasts (GFs) can participate in the immune response and play an immune-regulatory role. This study was to evaluate whether GFs can be differently activated and polarized into distinct functional subtypes in response to T helper type 1 (Th1), or Th2 stimuli. DESIGN:Human GFs were stimulated by t...
journal_title:Archives of oral biology
pub_type: 杂志文章
doi:10.1016/j.archoralbio.2019.04.019
更新日期:2019-06-01 00:00:00
abstract::Streptococcus mutans GS5, Lactobacillus casei DSM20011 and Actinomyces viscosus T14 produce artificial caries in the roots of extracted teeth. Roots were coated with wax leaving an 8 mm2 window exposed on the buccal surfaces, and then incubated for 8 days in the presence of the test organism, the synthetic medium bein...
journal_title:Archives of oral biology
pub_type: 杂志文章
doi:10.1016/0003-9969(88)90031-3
更新日期:1988-01-01 00:00:00
abstract::Radially directed inter-odontoblastic collagen fibres were observed in ultra-thin sections of the radicular pulp/predentine complex of rat molars. Bundles of fibres crossed the distal junctional complexes of the odontoblasts, went through the whole thickness of the predentine and were incorporated into the mineralized...
journal_title:Archives of oral biology
pub_type: 杂志文章
doi:10.1016/0003-9969(91)90082-6
更新日期:1991-01-01 00:00:00
abstract::The purpose of this study was firstly to characterize the changes occurring in size and form of the mineralizing maxillary second primary molar and first permanent molar crowns, and secondly to determine if similar changes in size and form characterize enamel apposition in the crowns of these teeth. Twenty-five primar...
journal_title:Archives of oral biology
pub_type: 杂志文章
doi:10.1016/s0003-9969(98)00034-x
更新日期:1998-07-01 00:00:00
abstract:OBJECTIVE:Streptococcus mutans is a principal bacterium that forms pathogenic biofilm involved in the development of dental caries. S. mutans possesses a quorum sensing system (QS) stimulated by competence stimulating peptide (CSP), which is associated with bacteriocin production, genetic competency and biofilm formati...
journal_title:Archives of oral biology
pub_type: 杂志文章
doi:10.1016/j.archoralbio.2019.04.010
更新日期:2019-06-01 00:00:00
abstract::These studies were made as a first step in elucidating unknown functions of enamel proteins in odontogenesis. The cytoplasm of ameloblasts and the proteins in dentine matrix before mineralization were stained with this monoclonal antibody. SDS-PAGE and Coomassie blue staining of proteins extracted from enamel showed s...
journal_title:Archives of oral biology
pub_type: 杂志文章
doi:10.1016/0003-9969(91)90113-9
更新日期:1991-01-01 00:00:00
abstract::Platelet-derived growth factor (PDGF) and insulin-like growth factor-I (IGF-I) interact to stimulate proliferation of fibroblasts in culture. Glucocorticoids variably effect the response of cultured fibroblasts to polypeptide growth factors. This study determined the effects of dexamethasone on growth-factor stimulati...
journal_title:Archives of oral biology
pub_type: 杂志文章
doi:10.1016/0003-9969(92)90009-w
更新日期:1992-02-01 00:00:00
abstract::This study examined the expression of MMP-2 and MMP-9 in normal and human malignant oral keratinocytes. The expression of pro-MMP-2 and pro-MMP-9 was heterogeneous in the malignant cell lines. Normal oral keratinocytes expressed less pro-MMP-2 and more pro-MMP-9 than their malignant counterparts. Cells that expressed ...
journal_title:Archives of oral biology
pub_type: 杂志文章
doi:10.1016/s0003-9969(03)00172-9
更新日期:2003-11-01 00:00:00
abstract::The histochemical muscle-fibre composition of the anterior and posterior belly of the human digastric muscle was analysed in young male adults. Both bellies, of differing embryological origin and supplied by different cranial nerves, showed a fibre composition similar to that of normal limb and trunk muscles. Type I, ...
journal_title:Archives of oral biology
pub_type: 杂志文章
doi:10.1016/0003-9969(82)90054-1
更新日期:1982-01-01 00:00:00
abstract::Lymphocytes isolated from chronically-inflamed tissues were assessed for their ability to produce lymphokines without further stimulation in vitro. Cells were extracted from tissue obtained from 42 patients undergoing periodontal surgery. Cultures were set up in triplicate and supernatants collected after 48 h were as...
journal_title:Archives of oral biology
pub_type: 杂志文章
doi:10.1016/0003-9969(85)90094-9
更新日期:1985-01-01 00:00:00
abstract:OBJECTIVES:The objective of this study was to evaluate the effect of platelet-rich plasma (PRP), platelet-rich fibrin (PRF), and concentrated growth factor (CGF) on bone healing. STUDY DESIGN:Twelve rabbits were included in this randomized, blinded, prospective study. 15-mm×10-mm-sized defects were created in the pari...
journal_title:Archives of oral biology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.archoralbio.2014.02.004
更新日期:2014-05-01 00:00:00
abstract:INTRODUCTION:Chronic kidney disease (CKD) and dialysis treatment could affect oral mucosa and cause qualitative or quantitative changes of saliva. OBJECTIVE:The aim of the study was to investigate oral manifestations, unstimulated salivary flow rate (USFR), salivary pH value and biochemical composition of saliva in no...
journal_title:Archives of oral biology
pub_type: 杂志文章
doi:10.1016/j.archoralbio.2019.04.021
更新日期:2019-06-01 00:00:00
abstract::Eight primary incisors obtained from a child with dentinogenesis imperfecta (DI) type II were examined histologically using light microscopy and scanning electron microscopy. In both the DI and control teeth, large dentinal canals were observed along the midline of the crown distributed mesial-distally and coursing to...
journal_title:Archives of oral biology
pub_type: 杂志文章
doi:10.1016/0003-9969(85)90116-5
更新日期:1985-01-01 00:00:00
abstract::The purpose was to examine the effect of brief intrusive forces on human pulpal blood flow (PBF). Laser Doppler flowmetric measurements were made from 17 vital upper left central incisors of 17 participants who had clinically healthy tooth crowns and periodontal tissues. Brief intrusive forces (0.5,1,5 N; duration 20 ...
journal_title:Archives of oral biology
pub_type: 杂志文章
doi:10.1016/s0003-9969(01)00049-8
更新日期:2001-09-01 00:00:00
abstract:OBJECTIVES:The initiation of the pain sensation experienced following the thermal stimulation of dentine has been correlated with fluid flow in the dentinal tubules. There may be other mechanisms. METHODS:This study examines this possibility using a mathematical model to simulate the temperature and thermal stress dis...
journal_title:Archives of oral biology
pub_type: 杂志文章
doi:10.1016/j.archoralbio.2011.02.011
更新日期:2011-09-01 00:00:00
abstract::The aim of this project was to develop an analytical procedure with the required level of sensitivity for the determination of glucose concentrations in small volumes of unstimulated fasting whole saliva. The technique involves high-performance ion-exchange chromatography at high pH and pulsed amperometric detection. ...
journal_title:Archives of oral biology
pub_type: 杂志文章
doi:10.1016/0003-9969(95)00121-2
更新日期:1996-02-01 00:00:00
abstract::Small, quasi-rhythmical tremor of the jaw occurs at rest and during voluntary movements. In peripheral limbs, tremor consists of a component due to mechanical resonance properties of the system, and a neurogenic component mediated by a central pacemaker or neural loops. The present study attempted to determine if thes...
journal_title:Archives of oral biology
pub_type: 杂志文章
doi:10.1016/s0003-9969(97)00091-5
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVE:To compare the mineralisation density (MD), morphology and histology of alveolar bone and cementum amongst VDR +/+, VDR -/-, and VDR -/- groups supplemented with a diet TD 96348, containing 20% lactose, 2.0% calcium and 1.25% phosphorous. METHODS:Four groups of mice (6 mice/group) were identified by genotypi...
journal_title:Archives of oral biology
pub_type: 杂志文章
doi:10.1016/j.archoralbio.2010.12.004
更新日期:2011-07-01 00:00:00
abstract::The biomechanical character of the periodontal ligament (PDL) is crucial in its response to functional and orthodontic forces. Collagen has been the primary subject of investigations in this field. Several studies, however, indicate that oxytalan fibres, which belong to the elastic fibre family, also contribute to the...
journal_title:Archives of oral biology
pub_type: 杂志文章,评审
doi:10.1016/j.archoralbio.2012.06.003
更新日期:2012-08-01 00:00:00
abstract::In magnetic-stimulation studies where motor-evoked potentials (MEP) are measured on different occasions, accurate relocation of the stimulation site on the scalp is essential. Here a novel method of locating neural stimulation sites was tested and the reproducibility of MEPs in the human masseter assessed. The heads o...
journal_title:Archives of oral biology
pub_type: 临床试验,杂志文章
doi:10.1016/s0003-9969(98)00050-8
更新日期:1998-08-01 00:00:00
abstract:OBJECTIVE:Low dose propranolol has previously been demonstrated to suppress bone remodelling. Therefore, its effect on orthodontic movement was tested. DESIGN:Rats were assigned as follows (n=5): animals with no orthodontic appliance (G1); the remaining groups were fitted with a Ni-Ti closed-coil spring ligated to the...
journal_title:Archives of oral biology
pub_type: 杂志文章
doi:10.1016/j.archoralbio.2014.06.006
更新日期:2014-10-01 00:00:00
abstract::Destrin, an actin-binding protein, is partly phosphorylated at Ser-2 (numbering on the matured form) in the resting rat parotid gland, and beta-adrenergic or cholinergic stimulation of this gland induces its dephosphorylation. In this study, we searched for the protein kinase involved in phosphorylation of destrin. We...
journal_title:Archives of oral biology
pub_type: 杂志文章
doi:10.1016/s0003-9969(03)00129-8
更新日期:2003-09-01 00:00:00
abstract::The classical hydrodynamic theory implicated fluid movement as a transducing mechanism in the production of dental sensitivity. This theory assumes that sensitive dentine must be permeable. Various measurements of dentine permeability are discussed, including: (1) factors that influence diffusive permeation across den...
journal_title:Archives of oral biology
pub_type: 杂志文章,评审
doi:10.1016/0003-9969(94)90191-0
更新日期:1994-01-01 00:00:00
abstract::Tissue transglutaminase (TGase 2) has been implicated in numerous cellular functions, i.e., apoptosis, differentiation, extracellular matrix protein cross-linking and organogenesis. Earlier report of the strong transient expression of TGase 2 localized at the anchoring sites of muscle bundles of human embryo and recen...
journal_title:Archives of oral biology
pub_type: 杂志文章
doi:10.1016/j.archoralbio.2005.01.007
更新日期:2005-09-01 00:00:00
abstract:BACKGROUND:Integrin-α5 (ITGA5) gene has been reported to be critical for the progression of several cancers. However, the effects of ITGA5 in oral squamous cell carcinoma (OSCC) remain unclear. METHODS:We firstly used bioinformatics methods to analyze the ITGA5 gene expression based on the public dataset. HO1-N-1 and ...
journal_title:Archives of oral biology
pub_type: 杂志文章
doi:10.1016/j.archoralbio.2019.03.007
更新日期:2019-05-01 00:00:00
abstract::The layer was evaluated by scanning electron microscopy and by measurement of hydraulic conductance before and after 2-min topical treatment with potassium chloride, neutral potassium oxalate, half-neutralized oxalic acid or both neutral and acidic oxalates. The treated smear layers were then re-evaluated microscopica...
journal_title:Archives of oral biology
pub_type: 杂志文章
doi:10.1016/0003-9969(85)90185-2
更新日期:1985-01-01 00:00:00
abstract::The 7S nerve-growth factor (7S NGF), high molecular weight epidermal growth factor (HMW-EGF) and their subunits were isolated from mouse submandibular gland. Plasminogen activator activity was found in the 7S NGF and HMW-EGF, as well as in the gamma subunit and EGF-binding protein. Later activities were two- or three-...
journal_title:Archives of oral biology
pub_type: 杂志文章
doi:10.1016/0003-9969(82)90094-2
更新日期:1982-01-01 00:00:00
abstract::A variable capacitance displacement transducer, previously employed for continuously monitoring movements of the rabbit mandibular incisor, was modified for use with the ferret mandibular canine. Comparing this tooth of limited growth with the tooth of continuous growth, similarities were seen in the reactions to extr...
journal_title:Archives of oral biology
pub_type: 杂志文章
doi:10.1016/0003-9969(83)90177-2
更新日期:1983-01-01 00:00:00
abstract:OBJECTIVE:To assess the prevalence of Staphylococcus aureus and methicillin resistant Staphylococcus aureus (MRSA) in plaque and tongue samples from systemically healthy subjects with periodontal health, gingivitis or chronic periodontitis. METHODS:After screening 720 potentially eligible subjects, 154 systemically he...
journal_title:Archives of oral biology
pub_type: 杂志文章
doi:10.1016/j.archoralbio.2015.06.009
更新日期:2015-09-01 00:00:00
abstract::Unitary discharges of periodontal mechanosensitive (PM) fibres were recorded from cat inferior alveolar nerve. More than half (66%) of the PM units were single-tooth ones sensitive to only one tooth. The majority (78%) responded sustainedly to stimulation of the mandibular canine tooth. The multitooth units responded ...
journal_title:Archives of oral biology
pub_type: 杂志文章
doi:10.1016/0003-9969(94)90036-1
更新日期:1994-01-01 00:00:00