Immunohistochemical and immunochemical detection of a similar epitope in enamel proteins and monocyte-macrophage protein recognized by mouse monoclonal antibody MOMA-2.

Abstract:

:These studies were made as a first step in elucidating unknown functions of enamel proteins in odontogenesis. The cytoplasm of ameloblasts and the proteins in dentine matrix before mineralization were stained with this monoclonal antibody. SDS-PAGE and Coomassie blue staining of proteins extracted from enamel showed several protein bands. Immunoblotting revealed that proteins recognized by this antibody were situated between 20-30 kDa. These results indicate that enamel proteins, presumably amelogenins, have an epitope resembling monocyte-macrophage protein. The findings suggest that epithelial-mesenchymal interaction in odontogenesis and preosteoblast-preosteoclast interaction in osteogenesis may be similar.

journal_name

Arch Oral Biol

journal_title

Archives of oral biology

authors

Nakamura M,Kindaichi K,Kagayama M

doi

10.1016/0003-9969(91)90113-9

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

619-22

issue

8

eissn

0003-9969

issn

1879-1506

pii

0003-9969(91)90113-9

journal_volume

36

pub_type

杂志文章
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  • Diffusion in mammalian tooth enamel in relation to the caries process.

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  • Overexpression and varied clinical significance of Th9 versus Th17 cells in distinct subtypes of oral lichen planus.

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    更新日期:1992-11-01 00:00:00

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