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Plasminogen activator activity in the subunits of mouse submandibular gland nerve-growth factor and epidermal growth factor.

Abstract：

:The 7S nerve-growth factor (7S NGF), high molecular weight epidermal growth factor (HMW-EGF) and their subunits were isolated from mouse submandibular gland. Plasminogen activator activity was found in the 7S NGF and HMW-EGF, as well as in the gamma subunit and EGF-binding protein. Later activities were two- or three-fold higher than those of original growth factors. The alpha subunit, beta subunit and low molecular weight EGF showed no activity. The gamma 1, gamma 2 and gamma 3 subunits of 7S NGF showed plasminogen activator activity almost equal to that of the original gamma subunit.

journal_name

Arch Oral Biol

journal_title

Archives of oral biology

authors

Hiramatsu M,Hatakeyama K,Kumegawa M,Minami N

doi

10.1016/0003-9969(82)90094-2

subject

Has Abstract

pub_date

1982-01-01 00:00:00

pages

517-8

issue

6

eissn

0003-9969

issn

1879-1506

journal_volume

27

pub_type

杂志文章

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