Abstract:
:Somatoform Disorders (SFMD) were recently described in Parkinson Disease (PD) and Dementia with Lewy Bodies (DLB). The present paper updates the observations in our cohort of patients and further details clinical phenomenology. Of 3178 patients consecutively referred to our Institutions from 1999, 1572 subjects had neurodegenerative diseases and 1718 psychiatric disorders. After 2-9 years of follow up, 488 patients were labelled as PD, 415 as Alzheimer Disease, 162 as DLB, 48 as Progressive Supranuclear Palsy, 48 as Multiple System Atrophy and 49 as Fronto-Temporal Dementia. The frequency of SFMD (DSM-IV-TR criteria) was determined in each diagnostic category by direct observation of SFMD symptoms, psychiatric interviews, SCL 90Rss, collection of previous general practitioners and hospital charts. The frequency of SFMD was considerably higher in DLB (29 patients, 18%) and PD (37 patients, 7.5%) than in any other group (0-2%). The frequency of SFMD in psychiatric patients was 2%. SFMD in PD and DLB were characterised by motor and non-motor patterns and were often accompanied by catatonic signs consisting of posturing stereotypies and negativism (55%). SFMD symptoms preceded PD motor signs by 6 months-5 years in 92% of the 29 DLB and 37 PD patients and in 70% SFMD were recurrent at follow-up. In 93% of these patients, hypochondria was a preceding or concomitant background.
journal_name
J Neurol Scijournal_title
Journal of the neurological sciencesauthors
Onofrj M,Thomas A,Tiraboschi P,Wenning G,Gambi F,Sepede G,Di Giannantonio M,Di Carmine C,Monaco D,Maruotti V,Ciccocioppo F,D'Amico MC,Bonanni Ldoi
10.1016/j.jns.2011.07.010subject
Has Abstractpub_date
2011-11-15 00:00:00pages
166-71issue
1-2eissn
0022-510Xissn
1878-5883pii
S0022-510X(11)00402-3journal_volume
310pub_type
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