Abstract：
OBJECTIVE:To identify patterns of sleep-wake transitions in the neonatal period that might differentiate premature infants who would show better or worse outcomes in multiple developmental domains across the first 5 years of life. METHODS:Participants were 143 low birth weight premature infants (mean birth weight: 1482 g; mean gestational age [GA]: 31.82 weeks). Sleep states were observed at a GA of 37 weeks in 10-second epochs over 4 consecutive evening hours and were analyzed through mathematical clustering. Neurobehavioral maturation was evaluated with the Neonatal Behavior Assessment Scale at discharge, emotional regulation was assessed during infant-mother and infant-father interactions at 3 and 6 months, cognitive development was measured at 6, 12, and 24 months, and verbal IQ, executive functions, and symbolic competence were tested at 5 years. RESULTS:Three types of state-transition patterns were identified, and no differences in birth weight, GA, or medical risk between the 3 groups were found. Infants whose sleep-state transitions were mainly characterized by shifts between quiet sleep and wakefulness exhibited the best development, including greater neonatal neuromaturation, less negative emotionality, better cognitive development, and better verbal, symbolic, and executive competences at 5 years. In comparison, infants who cycled mainly between states of high arousal, such as active sleep and cry, or between short episodes of active and quiet sleep showed poorer outcomes. CONCLUSIONS:Defining sleep organization on the basis of transitions between states proved useful for identifying risk and resilience indicators in neonatal behavior to predict trajectories of neurobehavioral, emotional, and cognitive growth.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Weisman O,Magori-Cohen R,Louzoun Y,Eidelman AI,Feldman Rdoi
10.1542/peds.2011-0047subject
Has Abstractpub_date
2011-10-01 00:00:00pages
706-14issue
4eissn
0031-4005issn
1098-4275pii
peds.2011-0047journal_volume
128pub_type
杂志文章相关文献
PEDIATRICS文献大全abstract：OBJECTIVE:Each year, children die from heat stroke after being left unattended in motor vehicles. In 2003, the total was 42, up from a national average of 29 for the past 5 years. Previous studies found that on days when ambient temperatures exceeded 86 degrees F, the internal temperatures of the vehicle quickly reache...
journal_title：Pediatrics
pub_type： 杂志文章
doi：10.1542/peds.2004-2368
更新日期：2005-07-01 00:00:00
abstract：OBJECTIVES:Bullying and being bullied have been recognized as health problems for children because of their association with adjustment problems, including poor mental health and more extreme violent behavior. It is therefore important to understand how bullying and being bullied affect the well-being and adaptive func...
journal_title：Pediatrics
pub_type： 杂志文章
doi：10.1542/peds.112.6.1231
更新日期：2003-12-01 00:00:00
abstract：:It is often difficult to measure cerebrospinal fluid (CSF) pressure in children. CSF flow through a spinal needle is described by the equation: Flow = pressure/(needle constant x relative viscosity). Thus, CSF flow rate during lumbar puncture can be used to estimate CSF pressure. Because the viscosity of CSF is approx...
journal_title：Pediatrics
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
abstract：OBJECTIVE:Using structural equation modeling, we sought to assess the system of services for children with special health care needs (CSHCN) and their families by using 14 key indicators of functional abilities of CSHCN, health insurance coverage, access to care, and the impact of their conditions on their families. M...
journal_title：Pediatrics
pub_type： 杂志文章
doi：10.1542/peds.2009-1255F
更新日期：2009-12-01 00:00:00
abstract：OBJECTIVE:To test how prevalence estimates and characteristics of children vary by the way that disability is defined. Specifically, to determine 1) the proportions of children identified as disabled by one particular operationalization of disability based on parental reports of three types of consequences (i.e., funct...
journal_title：Pediatrics
pub_type： 杂志文章
doi：10.1542/peds.101.6.1025
更新日期：1998-06-01 00:00:00
abstract：:During and after respiratory tract infections in 29 hospitalized infants, 12 cardiorespiratory measurements were performed on 24-hour recordings of ECG and respiratory activity. These measurements were compared with similar data obtained from 110 age-matched control infants without infection. Respiratory and heart rat...
journal_title：Pediatrics
pub_type： 杂志文章
doi：
更新日期：1986-07-01 00:00:00
abstract：:During a 12-month period 80 children greater than 3 months of age seen at an emergency room with acute fevers greater than or equal to 39.7 C (103.5 F) and no localizing signs of infection were studied using blood and buffy coat cultures to isolate bacteria and viruses. Bacteremia was identified in three children (3.8...
journal_title：Pediatrics
pub_type： 杂志文章
doi：
更新日期：1981-08-01 00:00:00
abstract：OBJECTIVE:Although vision screening for preschool children is recommended for detecting amblyopia, many pediatric and family medicine practices do not screen preschool-aged children. The aim of this study was to determine the effect of a training program for primary care clinical staff on vision screening behavior and ...
journal_title：Pediatrics
pub_type： 杂志文章
doi：10.1542/peds.112.1.e17
更新日期：2003-07-01 00:00:00
abstract：:Since 1961 the Committee on Nutrition of the American Academy of Pediatrics has recommended that prophylactic vitamin K be administered parenterally to all newborn infants, although the exact requirement for vitamin K in the newborn infant is unknown. There is little information about the vitamin K1 (phylloquinone, pr...
journal_title：Pediatrics
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:Cariogenicity of seven commonly prescribed liquid medications was studied. Sucrose content of the medications ranged from 0 to 70 gm/100 ml. Initial pH and buffering capacity were measured and found to vary widely among the medications. Intraoral microbial plaque pH changes were determined at intervals for 30 minutes ...
journal_title：Pediatrics
pub_type： 杂志文章
doi：
更新日期：1981-09-01 00:00:00
abstract：OBJECTIVE:To investigate the relationship between cognitive delay (CD) and behavior problems between ages 9 months and 5 years, while adjusting for covariates related to CD. METHODS:Data were from 4 waves of the Early Childhood Longitudinal Study, Birth Cohort (n = 8000). Children were classified as typically developi...
journal_title：Pediatrics
pub_type： 杂志文章
doi：10.1542/peds.2014-0259
更新日期：2014-09-01 00:00:00
abstract：OBJECTIVE:In the process of sampling blood through an umbilical arterial catheter (UAC), infant blood comes into stagnant contact with infusion solution in the "waste syringe" before being reinfused. We have previously demonstrated in vitro that this process is associated with less hemolysis of red blood cells (RBCs) w...
journal_title：Pediatrics
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1542/peds.114.2.377
更新日期：2004-08-01 00:00:00
abstract：:Physicians who prescribe a new drug that has not been approved for a specific indication or a specific age group frequently find themselves in a quandary. Physicians who prescribe "old," time-honored drugs usually do not consult the package insert or search for US Food and Drug Administration (FDA) approval. This stat...
journal_title：Pediatrics
pub_type： 杂志文章,评审
doi：
更新日期：1996-07-01 00:00:00
abstract：OBJECTIVE:To study the fat and energy intakes of children between 7 and 36 months of age with different growth patterns. METHODS:In the Special Turku coronary Risk factor Intervention Project for Babies, children were randomized to intervention (n = 540) and control groups (n = 522) at age 7 months. The intervention w...
journal_title：Pediatrics
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1542/peds.100.5.810
更新日期：1997-11-01 00:00:00
abstract：:A program that calculates a value of clearance for an individual patient prior to reaching steady state in the early stages of aminophylline therapy is presented. The program is written for the Texas Instruments TI-59 programmable calculator and may be used with or without the PC-100C printer. The program can provide ...
journal_title：Pediatrics
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：:The infant rumination syndrome has not been previously reported in a neonatal intensive care setting. We recently managed three infants in our newborn intensive care unit who developed rumination following chronic courses in the unit. The events leading to this condition in each infant are described, as well as the su...
journal_title：Pediatrics
pub_type： 杂志文章
doi：
更新日期：1980-10-01 00:00:00
abstract：PURPOSE:To analyze changes in the clinical condition at presentation and methods of establishing the diagnosis of infantile hypertrophic pyloric stenosis (IHPS). METHODS:Retrospective review of patients who underwent pyloromyotomy (PM) for suspected IHPS at two institutions from 1969 through 1994 was performed. For th...
journal_title：Pediatrics
pub_type： 杂志文章
doi：10.1542/peds.100.2.e9
更新日期：1997-08-01 00:00:00
abstract：OBJECTIVE:A widely published set of exchange transfusion criteria lowers critical bilirubin concentrations when the serum albumin falls to < 2.5 g/dL. Although acknowledging the role of bilirubin-albumin binding in bilirubin neurotoxicity, this approach may inadvertently produce two critical bilirubin concentrations. T...
journal_title：Pediatrics
pub_type： 杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：OBJECTIVE:Our purpose was to examine the significance of diffuse chorioamniotic hemosiderosis (DCH) on neonatal morbidity and mortality. METHODS:Using data from a retrospective case-control study, we analyzed 46 singleton placentas with DCH from infants who were delivered and/or admitted to the neonatal intensive care...
journal_title：Pediatrics
pub_type： 杂志文章
doi：10.1542/peds.113.4.800
更新日期：2004-04-01 00:00:00
abstract：:This article is a review of the effects that ingested dietary fiber has on gastrointestinal transit time. The various phases of gastrointestinal motility are considered, and the effect of fiber on these various components is explored. Fiber affects each phase of gastrointestinal motility differently; however, the most...
journal_title：Pediatrics
pub_type： 杂志文章,评审
doi：
更新日期：1995-11-01 00:00:00
abstract：BACKGROUND:In 2013-2014, an outbreak of serogroup B meningococcal disease occurred among persons linked to a New Jersey university (University A). In the absence of a licensed serogroup B meningococcal (MenB) vaccine in the United States, the Food and Drug Administration authorized use of an investigational MenB vaccin...
journal_title：Pediatrics
pub_type： 杂志文章
doi：10.1542/peds.2014-4015
更新日期：2015-05-01 00:00:00
abstract：:In this cross-sectional study, the vision-screening process is described for 8417 children aged 3 to 5 seen for health supervision in a group of 102 pediatric practices in 23 states and Puerto Rico. Three hundred forty children who failed screening (63% of those who failed) were followed up 2 months after initial scre...
journal_title：Pediatrics
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
abstract：BACKGROUND:Two of the most prevalent problems facing youth in the United States are injury and obesity. Obesity increases the risk of injury, prolongs recovery time, and increases morbidity among injured children. OBJECTIVE:The purpose of this study was to compare characteristics of injuries between obese and nonobese...
journal_title：Pediatrics
pub_type： 杂志文章
doi：10.1542/peds.2009-2367
更新日期：2010-04-01 00:00:00
abstract：BACKGROUND:To define the nature and frequency of brain injury and brain growth impairment in very preterm (VPT) infants by using MRI at term-equivalent age and to relate these findings to perinatal risk factors and 2-year neurodevelopmental outcomes. METHODS:MRI scans at term-equivalent age from 3 VPT cohorts (n = 325...
journal_title：Pediatrics
pub_type： 杂志文章
doi：10.1542/peds.2013-2336
更新日期：2014-08-01 00:00:00
abstract：:The frequency and severity of 17 side effects presumably associated with stimulant medication were assessed during a rigorous, triple-blind, placebo-controlled, crossover evaluation of methylphenidate, 0.3 and 0.5 mg/kg twice a day, in 83 children with attention deficit hyperactivity disorder. Side effects were rated ...
journal_title：Pediatrics
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1990-08-01 00:00:00
abstract：OBJECTIVE:Sleep-disordered breathing (SDB) is associated with insulin resistance and dyslipidemia in adults and in obese children. However, the prevalence of such metabolic abnormalities among snoring children is unknown. This study was done to prospectively assess the relative contribution of SDB and obesity to metabo...
journal_title：Pediatrics
pub_type： 杂志文章
doi：10.1542/peds.2004-2527
更新日期：2005-07-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Nosocomial rotavirus (nRV) infections represent an important part of rotavirus (RV)-associated morbidity. The incidence of nRV influences the estimated total RV disease burden, an important determinant of cost-effectiveness of RV vaccination programs. Our aim is to summarize the existing evide...
journal_title：Pediatrics
pub_type： 杂志文章,meta分析,评审
doi：10.1542/peds.2011-2779
更新日期：2012-04-01 00:00:00
abstract：CONTEXT:Rehabilitation for children with congenital hemiplegia to improve function in the impaired upper limb and enhance participation may be time-consuming and costly. OBJECTIVES:To systematically review the efficacy of nonsurgical upper-limb therapeutic interventions for children with congenital hemiplegia. METHOD...
journal_title：Pediatrics
pub_type： 杂志文章,meta分析,评审
doi：10.1542/peds.2008-3335
更新日期：2009-06-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Adults born preterm score lower on performance-based tests of executive functioning (EF) than their term-born peers. These test scores do not necessarily translate to application of these skills in an everyday environment. The objective of the study was to test differences between very low birt...
journal_title：Pediatrics
pub_type： 杂志文章
doi：10.1542/peds.2012-0839
更新日期：2013-01-01 00:00:00
abstract：:After the introduction of the hepatitis B vaccine in the United States in 1982, a greater than 90% reduction in new infections was achieved. However, approximately 1000 new cases of perinatal hepatitis B infection are still identified annually in the United States. Prevention of perinatal hepatitis B relies on the pro...
journal_title：Pediatrics
pub_type： 杂志文章
doi：10.1542/peds.2017-1870
更新日期：2017-09-01 00:00:00
