Radiotherapy Plus GnRH Analogue Versus High Dose Bicalutamide: A Case Control Study.

abstract：BACKGROUND:miR-96 is reported to inhibit reversion cysteine-rich Kazal motif (RECK), which is associated with tumor invasion, in solid cancer types (e.g. breast cancer, non-small cell lung cancer, esophageal cancer). The purpose of this study is to clarify whether miR-96 is similarly associated with tumor invasion in c...

journal_title：Anticancer research

authors： Iseki Y,Shibutani M,Maeda K,Nagahara H,Fukuoka T,Matsutani S,Hirakawa K,Ohira M

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND/AIM:Cancer incidence and mortalities are growing worldwide, therefore research and development of more effective and less invasive treatments, such as photodynamic therapy, are needed. Herein, we investigated the methylene blue (MB) photoactivation effects in lung epithelial cells (BEAS-2B) and lung adenocar...

journal_title：Anticancer research

authors： Rodríguez-Córdova RJ,Gutiérrez-Valenzuela CA,Bojang P,Esquivel R,Hernández P,Ramos KS,Guzmán-Zamudio R,Lucero-Acuña A

更新日期：2019-07-01 00:00:00

abstract：:Oxazolinodoxorubicin, a doxorubicin analog with a modified daunosamine moiety was synthesized. The properties of this compound and the parent doxorubicin were compared. The cytotoxicity in vitro studies against several human tumor cell lines (PC-3, MCF-7, SW707, HL-60, RPMI 8226, ACHN) showed higher antiproliferative ...

journal_title：Anticancer research

authors： Lukawska M,Klopotowska D,Milczarek M,Wietrzyk J,Studzian K,Szmigiero L,Porebska A,Oszczapowicz I

更新日期：2012-07-01 00:00:00

abstract：:Variants of the Bomirski family of hamster melanomas whose proliferative rates differ inversely with the genetically determined degree of melanogenesis were probed for two proteins critical in melanogenesis: tyrosinase and catalase-B (gp 75). The parental black tumor Ma contained both proteins in abundance. The amelan...

journal_title：Anticancer research

authors： Slominski A,Costantino R,Howe J,Moellmann G

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Nuclear morphometry can be expected to improve the distinction between benign and malignant lesions. PATIENTS AND METHODS:Forty fine-needle aspiration biopsy (FNAB) samples fixed in 50% ethanol were collected at the African Oncology Institute, Sabratha, Libya, during the period 2004-2007. All diagnoses repo...

journal_title：Anticancer research

authors： Abdalla F,Boder J,Buhmeida A,Hashmi H,Elzagheid A,Collan Y

更新日期：2008-11-01 00:00:00

abstract：:We have previously shown biopsies from human malignant melanoma, as well as a cell line (MELUR) derived from human malignant melanoma cells, to contain dexamethasone (DEX) - and medroxyprogesterone acetate (MPA) - binding macromolecules exhibiting properties of glucocorticoid receptors from well-known target organs. I...

journal_title：Anticancer research

authors： Bojar H,Fabry W

更新日期：1985-03-01 00:00:00

abstract：AIM:Combined cisplatin-topotecan therapy is standard care for advanced cervical cancer, however it is associated with haematotoxicity and nephrotoxicity. This trial was designed to assess the combination of carboplatin which is less nephrotoxic, and oral topotecan. PATIENTS AND METHODS:Patients with advanced/recurrent...

journal_title：Anticancer research

authors： Kurtz JE,Freyer G,Joly F,Gladieff L,Kaminski MC,Fabbro M,Floquet A,Hardy-Bessard AC,Raban N,Ray-Coquard I,Pujade-Lauraine E,GINECO Group, France.

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Cancer of the small intestine is a rare disease, and its clinical features have not been clearly elucidated. Techniques such as double balloon endoscopy and capsule endoscopy allow the preoperative diagnosis of cancer of the small intestine, but this cancer is often detected at an advanced state and in many ...

journal_title：Anticancer research

authors： Higashi D,Ishibashi Y,Tamura T,Nii K,Egawa Y,Koga M,Tomiyasu T,Harimura T,Tanaka R,Futatsuki R,Noda S,Futami K,Maekawa T,Takaki Y,Hirai F,Matsui T

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:The E-cadherin/beta-catenin complex plays a crucial role in epithelial cell-cell adhesion and in the maintenance of tissue architecture. We previously reported aberrant expression of beta-catenin in endometrial carcinomas. However, the expression and correlation of E-cadherin and beta-catenin in normal and m...

journal_title：Anticancer research

authors： Shih HC,Shiozawa T,Miyamoto T,Kashima H,Feng YZ,Kurai M,Konishi I

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND/AIM:Phenolic compounds isolated from Dendrobium ellipsophyllum Tang & Wang (Orchidaceae) have been shown to possess potential pharmacological activity; however, their anticancer as well as anti-metastasis activities are largely unknown. The aim of the present study was to isolate active compounds from D. ell...

journal_title：Anticancer research

authors： Tanagornmeatar K,Chaotham C,Sritularak B,Likhitwitayawuid K,Chanvorachote P

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND/AIM:Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a novel clinical approach to the treatment of peritoneal carcinomatosis. A well-established, not anatomic ex vivo PIPAC model was used to investigate the influence of changes in internal pressure, distance of the Micropump(©) (MIP) to the distri...

journal_title：Anticancer research

authors： Khosrawipour V,Khosrawipour T,Falkenstein TA,Diaz-Carballo D,Förster E,Osma A,Adamietz IA,Zieren J,Fakhrian K

更新日期：2016-09-01 00:00:00

abstract：:Transcatheter embolization is considered to be less effective for early-stage hepatocellular carcinomas (HCCs) without a hypervascular arterial supply. In the present case report, a 65-year-old male with hepatitis type C and non-hypervascular HCC located in the hepatic hilum was successfully treated by bland transarte...

journal_title：Anticancer research

authors： Tanaka T,Maeda S,Nishiofuku H,Masada T,Sato T,Anai H,Sakaguchi H,Kichikawa K

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:The aim of this retrospective study was to evaluate the clinical relevance of serum p53 antibody (S-p53Ab) as a biomarker and to investigate whether its diagnostic value could be improved when combined with other biomarkers of gastric cancer (GC). PATIENTS AND METHODS:Serum samples were obtained preoperativ...

journal_title：Anticancer research

authors： Kunizaki M,Fukuda A,Wakata K,Tominaga T,Nonaka T,Miyazaki T,Matsumoto K,Sumida Y,Hidaka S,Yasutake T,Sawai T,Hamamoto R,Nanashima A,Nagayasu T

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND/AIM:We previously identified that promoter DNA methylation of cysteine dioxygenase type 1 (CDO1) and homeobox only protein homeobox (HOPX) were both cancer specific, and have a clinical potential as prognostic biomarkers in breast cancer (BC). The present study compared the differential prognostic relevance ...

journal_title：Anticancer research

authors： Tanaka Y,Kosaka Y,Waraya M,Yokota K,Harada H,Kaida T,Kikuchi M,Minatani N,Nishimiya H,Katoh H,Sengoku N,Watanabe M,Yamashita K

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND/AIM:Combretastatin A-4 phosphate (CA4P) is a vascular-disrupting agent which affects the level of circulating neutrophils. Since tumor-associated macrophages and neutrophils may collaborate, we compared the effect of CA4P treatment on monocytes/macrophages and neutrophils. MATERIAL AND METHODS:CDF1 mice wit...

journal_title：Anticancer research

authors： Bohn AB,Brems-Eskildsen AS,Møller BK,Horsman MR

更新日期：2015-05-01 00:00:00

abstract：:Upper gastrointestinal malignancies are associated with a high disease burden worldwide, and esophageal and gastric cancers represent the most common entities. Given a lack of early characteristic symptoms and potent screening instruments, the majority of patients present with advanced disease at the time of diagnosis...

journal_title：Anticancer research

authors： Bolm L,Käsmann L,Paysen A,Karapetis C,Rades D,Wellner UF,Keck T,Watson DI,Hummel R,Hussey DJ

更新日期：2018-06-01 00:00:00

abstract：:Secreted pro-cathepsin B of HS-24 human lung-tumour cells, human alveolar macrophages and Wi-38 human lung-fibroblast cells was pre-purified by ion exchange chromatography and investigated by 2D gel electrophoresis. Four (Wi-38), six (HS-24) and ten (alveolar macrophages) polypeptides differing in charge, but with the...

journal_title：Anticancer research

authors： Werle B,Ebert W,Klein W,Spiess E

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND/AIM:Recent studies implied a significant role of hypoxia-inducible factor-1α (HIF1α) in cell transformation. This study aimed to assess the effects of HIF1α on the epithelial-to-mesenchymal transition (EMT) and tumorigenesis of lung adenocarcinoma cells. MATERIALS AND METHODS:Invasion, migration and colony ...

journal_title：Anticancer research

authors： Liu KH,Tsai YT,Chin SY,Lee WR,Chen YC,Shen SC

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND/AIM:The expression of corticotropin-releasing hormone (CRH)-related peptides involved in stress response in colorectal cancer has been reported. We examined the involvement of CRH-related peptides in cellular stress caused by anticancer drugs in colorectal cancer. MATERIALS AND METHODS:Changes in the expres...

journal_title：Anticancer research

authors： Kuwata GO,Ikeda K,Manome Y

更新日期：2020-08-01 00:00:00

abstract：:The limited restriction of eucaryotic chromosomes would facilitate our understanding of the aberrant genomes of genetic diseases and cancer. We have described methods for methylating eucaryotic chromosomes embedded in agarose plugs. We now describe how Cla I methylase can be utilized in a methylation-dependent restric...

journal_title：Anticancer research

authors： Wilson WW,Mebane EW,Hoffman RM

更新日期：1993-01-01 00:00:00

abstract：:Anaplastic lymphoma kinase (ALK) rearrangements were first implicated as driving mutations in non-small cell lung cancer in 2007. Since then, a number of novel, small-molecule inhibitors directed against the ALK receptor have demonstrated superiority over standard chemotherapies in the treatment of ALK rearrangement-p...

journal_title：Anticancer research

authors： Millett RL,Elkon JM,Tabbara IA

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND/AIM:The European MRI and Rectal Cancer Surgery (EuMaRCS) score was proposed to identify preoperatively difficult laparoscopic total mesorectal excision (L-TME) for locally advanced rectal cancer (LARC). This study aimed to test EuMaRCS's validity. PATIENTS AND METHODS:Data were retrieved from a European mul...

journal_title：Anticancer research

authors： de'ANGELIS N,Martínez-Pérez A,Vitali GC,Pigneur F,Luciani A,Brunetti F,Kraft M,Martí-Martínez E,Moroni P,Espin E,Ris F,Pucciarelli S,EuMaRCS Study Group.

更新日期：2020-04-01 00:00:00

abstract：:Currently, feeder cells are γ-irradiated immediately before use for the ex vivo expansion of natural killer (NK) cells from human peripheral blood. Storing irradiated feeder cells by cryopreserving them in multiple vials would be more convenient than irradiating cells each time they are needed. We compared NK cell exp...

journal_title：Anticancer research

authors： Baek HJ,Kim JS,Yoon M,Lee JJ,Shin MG,Ryang DW,Kook H,Kim SK,Cho D

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Prolonged exposure to asbestos, a potent carcinogen, has been the generally accepted factor responsible for the development of human mesotheliomas. Recent reports documenting the detection of SV40 DNA in human mesotheliomas suggest the possibility that this known tumor virus may be an additional factor invol...

journal_title：Anticancer research

authors： Arrington AS,Lednicky JA,Butel JS

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Satraplatin (JM216; bis-acetatoammine-dichlorocyclohexylamine platinum (IV)) is a platinum (Pt) complex developed in an attempt to circumvent tumour resistance and which can be administered by the oral route. The fate of platinum delivered by this oral formulation administered at various doses under the 5 or...

journal_title：Anticancer research

authors： Vouillamoz-Lorenz S,Buclin T,Lejeune F,Bauer J,Leyvraz S,Decosterd LA

更新日期：2003-05-01 00:00:00

abstract：:Cells cultured as spheroids present an heterogeneity similar to that of tumours in vivo. In the spheroid peripheral layers, cells are proliferating, deeper cells are non-cycling, when in the aggregate centre, cells form often a necrotic core. A multicellular resistance is related on the cell contact to other cells or ...

journal_title：Anticancer research

authors： Desoize B,Gimonet D,Jardiller JC

更新日期：1998-11-01 00:00:00

abstract：:To determine the group of patients for whom a biological response modifier is useful, the efficacy of postoperative adjuvant immunotherapy was investigated with regard to infiltration of dendritic cells (DC) in patients with advanced gastric cancer who underwent absolute curative resection. The infiltration of DC was ...

journal_title：Anticancer research

authors： Tsujitani S,Kakeji Y,Orita H,Watanabe A,Kohnoe S,Baba H,Anai H,Maehara Y,Sugimachi K

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND/AIM:Oxaliplatin-induced neurotoxicity (OIN) can be severe and dose-limiting with clinically significant symptoms that persist for years. Few published reports have described postoperative exacerbation of OIN and more longitudinal data are needed to better characterize the phenomenon. PATIENTS AND METHODS:We...

journal_title：Anticancer research

authors： Gonzalez A,Walker EJ,Van Loon K,Cinar P,Atreya CE

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Granulosa cell tumor of the testis is a rare intermediate stromal cell tumor that can be distinguished in the adult and juvenile type. The juvenile type is the most common reason for scrotal swelling in newborns under the age of six months. Less than fifty cases of this disease entity have been reported in t...

journal_title：Anticancer research

authors： Zugor V,Labanaris AP,Witt J,Seidler A,Weingärtner K,Schott GE

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Due to the longer life expectancy of the world's population, the number of elderly cirrhotic patients undergoing surgery for hepatocellular carcinoma (HCC) is increasing. Our study evaluates the benefits of hepatic resections for HCC in cirrhotic patients aged over 65, analysing the early and long-term surgi...

journal_title：Anticancer research

authors： Mercantini P,Corigliano N,Lucandri G,Balducci G,Amodio PM,Ramacciato G,Ziparo V

更新日期：2002-11-01 00:00:00