Abstract:
BACKGROUND/AIM:The European MRI and Rectal Cancer Surgery (EuMaRCS) score was proposed to identify preoperatively difficult laparoscopic total mesorectal excision (L-TME) for locally advanced rectal cancer (LARC). This study aimed to test EuMaRCS's validity. PATIENTS AND METHODS:Data were retrieved from a European multicenter database, including patients with mid/low LARC, treated with neoadjuvant chemoradiation therapy and L-TME with primary anastomosis. The EuMaRCS score was calculated on: BMI>30 (3 points), interspinous distance<96.4 mm (2 points), ymrT stage≥T3b (4 points), and male sex (1 point). RESULTS:The sample was composed of 141 patients, of whom 23 (16.3%) had a difficult L-TME. The EuMaRCS score demonstrated high accuracy in predicting difficult surgery (AROC: 0.806, 95%CI=0.72-0.88), with a cut-off >3 being associated with the best balance in sensitivity (82.6%) and specificity (66.1%). CONCLUSION:The EuMaRCS score represents a validated tool to predict preoperatively difficult L-TME in LARC patients.
journal_name
Anticancer Resjournal_title
Anticancer researchauthors
de'ANGELIS N,Martínez-Pérez A,Vitali GC,Pigneur F,Luciani A,Brunetti F,Kraft M,Martí-Martínez E,Moroni P,Espin E,Ris F,Pucciarelli S,EuMaRCS Study Group.doi
10.21873/anticanres.14166subject
Has Abstractpub_date
2020-04-01 00:00:00pages
2079-2087issue
4eissn
0250-7005issn
1791-7530pii
40/4/2079journal_volume
40pub_type
杂志文章abstract::Tricot et al have reported that the nucleoside analog tiazofurin can induce hematologic remissions in patients with chronic myelogenous leukemia in blast crisis (CML-BC). These reports prompted us to begin a derivative, phase II trial of tiazofurin in CML-BC to determine if the promising findings reported by these inv...
journal_title:Anticancer research
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doi:
更新日期:1999-11-01 00:00:00
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