Predictive scoring system assessing the need for intraoperative blood transfusions during hepatectomy for hepatocellular carcinoma.

Abstract:

BACKGROUND:It is of great clinical concern to preoperatively predict the need for blood transfusions during hepatectomy for hepatocellular carcinoma (HCC). PATIENTS AND METHODS:A total of 168 consecutive patients undergoing elective hepatectomy for HCC were retrospectively reviewed. We investigated preoperative factors potentially influencing intraoperative blood transfusion and established a predictive scoring system for intraoperative blood transfusion. RESULTS:Thirty-eight patients (22.6%) received red cell blood transfusion during surgery. A preoperative predicting scoring system for blood transfusion was constructed using the following four factors: platelet count <10×10(4)/mm(3) (2 points), α-fetoprotein ≥80 ng/ml (1 point), tumor size ≥4.0 cm (1 point), and major hepatectomy (1 point). The nomogram showed an area under the curve (AUC) of 0.760. This scoring system was highly predictive for blood transfusion (AUC=0.758). When the score was 0 points, the incidence of intraoperative blood transfusion was 3%. The rate increased to 10% and 38% when the score was 1 and 2 points, respectively, and reached 45% when the score was 3 points or more. CONCLUSION:This predictive scoring system would be useful for preoperatively assessing the need for intraoperative blood transfusions during hepatectomy for HCC.

journal_name

Anticancer Res

journal_title

Anticancer research

authors

Yamamoto Y,Ikoma H,Morimura R,Konishi H,Murayama Y,Komatsu S,Shiozaki A,Kuriu Y,Kubota T,Nakanishi M,Ichikawa D,Fujiwara H,Okamoto K,Sakakura C,Ochiai T,Otsuji E

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

313-8

issue

1

eissn

0250-7005

issn

1791-7530

pii

34/1/313

journal_volume

34

pub_type

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