Relationship Between Preoperative Erythrocyte Sedimentation Rate and Survival After Surgery in Patients with Colorectal Cancer.

Abstract:

AIM:To investigate the relationship between erythrocyte sedimentation rate (ESR) and postoperative survival of patients with colorectal cancer (CRC). MATERIALS AND METHODS:Relationships between clinical characteristics and overall survival (OS) of patients with CRC were investigated using multivariate analysis. Receiver operating characteristics curve analysis was performed to decide the ideal cut-off values of clinical characteristics to divide patients into two groups, which were then compared using a survival curve analysis. RESULTS:Three hundred and eleven patients with CRC undergoing surgery were enrolled. Multivariate analysis showed that ESR >40 mm/h (hazard ratio(HR)=2.601, 95% confidence interval(CI)=1.187-5.697; p=0.017) was associated with poorer OS, along with non-tubular pathology (p=0.034). Kaplan-Meier analysis revealed that patients with ESR >40 mm/h had poorer postoperative survival than those without ESR elevation (p<0.001). CONCLUSION:Preoperative elevation of ESR (>40 mm/h) can predict poorer postoperative survival in patients with CRC.

journal_name

Anticancer Res

journal_title

Anticancer research

authors

Shibuya N,Ishizuka M,Takagi K,Iwasaki Y,Hachiya H,Aoki T,Kubota K

doi

10.21873/anticanres.13049

subject

Has Abstract

pub_date

2018-12-01 00:00:00

pages

6783-6788

issue

12

eissn

0250-7005

issn

1791-7530

pii

38/12/6783

journal_volume

38

pub_type

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