Differential neuronal changes in medial prefrontal cortex, basolateral amygdala and nucleus accumbens after postweaning social isolation.

abstract：:Animal models of Alzheimer's disease (AD) can be used to determine the progressive neurodegeneration characteristics of AD in vivo using magnetic resonance imaging (MRI). Given the need for therapeutic interventions before the onset of frank AD, it is critical to examine if AD models demonstrate neuroanatomical remode...

journal_title：Brain structure & function

authors： Kong V,Devenyi GA,Gallino D,Ayranci G,Germann J,Rollins C,Chakravarty MM

更新日期：2018-09-01 00:00:00

abstract：:Positive social interactions during the juvenile and adolescent phases of life are essential for proper social and cognitive development in mammals, including humans. During this developmental period, there is a marked increase in peer-peer interactions, signified by the abundance of social play behaviour. Despite its...

journal_title：Brain structure & function

authors： van Kerkhof LW,Trezza V,Mulder T,Gao P,Voorn P,Vanderschuren LJ

更新日期：2014-07-01 00:00:00

abstract：:The structure of neurons in the central auditory system is vulnerable to various kinds of acoustic exposures during the critical postnatal developmental period. Here we explored long-term effects of exposure to an acoustically enriched environment (AEE) during the third and fourth weeks of the postnatal period in rat ...

journal_title：Brain structure & function

authors： Svobodová Burianová J,Syka J

更新日期：2020-09-01 00:00:00

abstract：:Early-life sleep deprivation (ESD) is a serious condition with severe metabolic sequelae. The pineal hormone melatonin plays an important role in homeostatic regulation of metabolic function. Considering norepinephrine-mediated Ca(2+) influx and subsequent protein kinase A (PKA) activation is responsible for downstrea...

journal_title：Brain structure & function

authors： Chen LY,Tiong C,Tsai CH,Liao WC,Yang SF,Youn SC,Mai FD,Chang HM

更新日期：2015-03-01 00:00:00

abstract：:This study investigates the mechanism of action of spadin, a putative fast-acting peptidic antidepressant (AD) and a functional blocker of the K(+) TREK-1 channel, in relation with the medial prefrontal cortex (mPFC)-dorsal raphé (DRN) serotonergic (5-HT) neurons connectivity. Spadin increased 5-HT neuron firing rate ...

journal_title：Brain structure & function

authors： Moha ou Maati H,Bourcier-Lucas C,Veyssiere J,Kanzari A,Heurteaux C,Borsotto M,Haddjeri N,Lucas G

更新日期：2016-01-01 00:00:00

abstract：:Although several novel approaches for hippocampal subregion delineation have been developed, they need to be applied prospectively and may be limited by long scan times, the use of high field (>3T) imaging systems, and limited reliability metrics. Moreover, the majority of MR imaging data collected to date has employe...

journal_title：Brain structure & function

authors： Rhindress K,Ikuta T,Wellington R,Malhotra AK,Szeszko PR

更新日期：2015-11-01 00:00:00

abstract：:Brain pathology in Friedreich ataxia is characterized by progressive degeneration of nervous tissue in the brainstem, cerebellum and cerebellar peduncles. Evidence of cerebral involvement is however equivocal. This brain imaging study investigates cerebello-cerebral white matter connectivity in Friedreich ataxia with ...

journal_title：Brain structure & function

authors： Zalesky A,Akhlaghi H,Corben LA,Bradshaw JL,Delatycki MB,Storey E,Georgiou-Karistianis N,Egan GF

更新日期：2014-05-01 00:00:00

abstract：:During the development of the central nervous system, the immature neurons suffer different migration processes. It is well known that Nkx2.1-positive ventricular layer give rise to critical tangential migrations into different regions of the developing forebrain. Our aim was to study this phenomenon in the hypothalam...

journal_title：Brain structure & function

authors： Murcia-Ramón R,Company V,Juárez-Leal I,Andreu-Cervera A,Almagro-García F,Martínez S,Echevarría D,Puelles E

更新日期：2020-12-01 00:00:00

abstract：:Ambulatory locomotion in the rodent is robustly activated by unilateral infusions into the basal forebrain of type A gamma-aminobutyric acid receptor antagonists, such as bicuculline and picrotoxin. The present study was carried out to better localize the neuroanatomical substrate(s) underlying this effect. To accompl...

journal_title：Brain structure & function

authors： Zahm DS,Schwartz ZM,Lavezzi HN,Yetnikoff L,Parsley KP

更新日期：2014-03-01 00:00:00

abstract：:To date, hampered physiological function after exposure to microgravity has been primarily attributed to deprived peripheral neuro-sensory systems. For the first time, this study elucidates alterations in human brain function after long-duration spaceflight. More specifically, we found significant differences in resti...

journal_title：Brain structure & function

authors： Demertzi A,Van Ombergen A,Tomilovskaya E,Jeurissen B,Pechenkova E,Di Perri C,Litvinova L,Amico E,Rumshiskaya A,Rukavishnikov I,Sijbers J,Sinitsyn V,Kozlovskaya IB,Sunaert S,Parizel PM,Van de Heyning PH,Laureys S,Wuyts F

更新日期：2016-06-01 00:00:00

abstract：:The organization of the pallial derivatives across vertebrates follows a comparable elementary arrangement, although not all of them possess a layered cortical structure as sophisticated as the cerebral cortex of mammals. However, its expansion along evolution has only been possible by the development and coevolution ...

journal_title：Brain structure & function

authors： Jiménez S,López JM,Lozano D,Morona R,González A,Moreno N

更新日期：2020-09-01 00:00:00

abstract：:The neural underpinnings of human emotional expression are thought to be unevenly distributed among the two brain hemispheres. However, little is known on the anatomy supporting this claim, particularly in the cerebral white matter. Here, we explored the relationship between hemi-face dominance in emotional expression...

journal_title：Brain structure & function

authors： Ioannucci S,George N,Friedrich P,Cerliani L,Thiebaut de Schotten M

更新日期：2020-05-01 00:00:00

abstract：:Reduction in the amount of brain-derived neurotrophic factor (BDNF) in corticostriatal afferents is thought to contribute to the vulnerability of medium spiny striatal neurons in Huntington's disease. In young Bdnf heterozygous ((+/-)) mice, striatal medium spiny neurons (MSNs) express less preprodynorphin (PPD), prep...

journal_title：Brain structure & function

authors： Saylor AJ,McGinty JF

更新日期：2010-08-01 00:00:00

abstract：:The primary systems framework has been used to relate behavioural performance across many different language activities to the status of core underpinning domain-general cognitive systems. This study provided the first quantitative investigation of this account at both behavioural and neural levels in a group of patie...

journal_title：Brain structure & function

authors： Woollams AM,Halai A,Lambon Ralph MA

更新日期：2018-11-01 00:00:00

abstract：:Interest in the study of brain connectivity is growing, particularly in understanding the dynamics of the structural/functional connectivity relation. Structural and functional connectivity are most often analysed independently of each other. Track-weighted functional connectivity (TW-FC) was recently proposed as a me...

journal_title：Brain structure & function

authors： Calamante F,Smith RE,Liang X,Zalesky A,Connelly A

更新日期：2017-11-01 00:00:00

abstract：:Agenesis of the corpus callosum (AgCC) is a congenital condition associated with wide-ranging emotional and social impairments often overlapping with the diagnostic criteria for autism. Mapping functional connectivity in the acallosal brain can help identify neural correlates of the deficits associated with this condi...

journal_title：Brain structure & function

authors： Sforazzini F,Bertero A,Dodero L,David G,Galbusera A,Scattoni ML,Pasqualetti M,Gozzi A

更新日期：2016-03-01 00:00:00

abstract：:Serotonin neurons arise from the brainstem raphe nuclei and send their projections throughout the brain to release 5-HT which acts as a modulator of several neuronal populations. Previous electron microscopy studies in rats have morphologically determined the distribution of 5-HT release sites (boutons) in certain bra...

journal_title：Brain structure & function

authors： Belmer A,Klenowski PM,Patkar OL,Bartlett SE

更新日期：2017-04-01 00:00:00

abstract：:The effect of intracortical microstimulation has been studied in several cortical areas from motor to sensory areas. The frontal pole has received particular attention, and several microstimulation studies have been conducted in the frontal eye field, supplementary eye field, and the premotor ear-eye field, but no mic...

journal_title：Brain structure & function

authors： Lanzilotto M,Perciavalle V,Lucchetti C

更新日期：2015-03-01 00:00:00

abstract：:Sex differences are widespread across vertebrate nervous systems. Such differences are sometimes reflected in the neural substrate via neuroanatomical differences in brain region volume. One brain region that displays sex differences in its associated functions and pathologies is the striatum, including the caudate-pu...

journal_title：Brain structure & function

authors： Wong JE,Cao J,Dorris DM,Meitzen J

更新日期：2016-11-01 00:00:00

abstract：:The extensive and increasing use of structural neuroimaging in the neurosciences rests on the assumption of an intimate relationship between structure and function in the human brain. However, few studies have examined the relationship between advanced magnetic resonance imaging (MRI) indices of cerebral structure and...

journal_title：Brain structure & function

authors： Elvsåshagen T,Moberget T,Bøen E,Hol PK,Malt UF,Andersson S,Westlye LT

更新日期：2015-03-01 00:00:00

abstract：:Distribution of bromodeoxyuridine immunoreactive (BrdU-IR) cell nuclei was analyzed at proximal and remote cortical sites in adult Cebus apella monkeys after a programmed surgical lesion placed either in the prefrontal or in the striate cerebral cortex. Increased GFAP-IR and vimentin-IR astrocytes, as well as Isolecti...

journal_title：Brain structure & function

authors： Lanosa XA,Yáñez A,Alzugaray S,Colombo JA

更新日期：2012-04-01 00:00:00

abstract：:Using T 1-weighted MRI at two different magnetic field strengths, the enhanced longitudinal relaxivity due to paramagnetic manganese ions in mouse brain in vivo is shown to reflect reduced intracellular mobility. One day after systemic administration of manganese chloride, increases of the longitudinal relaxation rate...

journal_title：Brain structure & function

authors： Watanabe T,Frahm J,Michaelis T

更新日期：2015-01-01 00:00:00

abstract：:The vestibulo-ocular reflex (VOR) adaptation is an ideal model for investigating how the neurosteroid 17 beta-estradiol (E2) contributes to the modification of behavior by regulating synaptic activities. We hypothesized that E2 impacts VOR adaptation by affecting cerebellar synaptic plasticity at the parallel fiber-Pu...

journal_title：Brain structure & function

authors： Dieni CV,Ferraresi A,Sullivan JA,Grassi S,Pettorossi VE,Panichi R

更新日期：2018-03-01 00:00:00

abstract：:The midline and intralaminar thalamic nuclei (MITN), locus coeruleus (LC) and cingulate cortex contain nociceptive neurons. The MITN that project to cingulate cortex have a prominent innervation by norepinephrinergic axons primarily originating from the LC. The hypothesis explored in this study is that MITN neurons th...

journal_title：Brain structure & function

authors： Vogt BA,Hof PR,Friedman DP,Sikes RW,Vogt LJ

更新日期：2008-08-01 00:00:00

abstract：:The dorsal part of the developing telencephalon is one of the brain areas that has suffered most drastic changes throughout vertebrate evolution. Its evolutionary increase in complexity was thought to be partly achieved by the appearance of a new neurogenic niche in the embryonic subventricular zone (SVZ). Here, a new...

journal_title：Brain structure & function

authors： Docampo-Seara A,Lagadec R,Mazan S,Rodríguez MA,Quintana-Urzainqui I,Candal E

更新日期：2018-11-01 00:00:00

abstract：:Perineuronal nets (PNNs) are aggregates of extracellular matrix molecules surrounding several types of neurons in the adult CNS, which contribute to stabilising neuronal connections. Interestingly, a reduction of PNN number and staining intensity has been observed in conditions associated with plasticity in the adult ...

journal_title：Brain structure & function

authors： Faralli A,Dagna F,Albera A,Bekku Y,Oohashi T,Albera R,Rossi F,Carulli D

更新日期：2016-07-01 00:00:00

abstract：:Nitric oxide (NO) is well demonstrated to act as a neuronal messenger in neurotransmission in vertebrate animals. We are for the first time reporting nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d) and neuronal nitric oxide synthase (nNOS) in the Mauthner cells (MC) of the carp, Labeo rohita brain dur...

journal_title：Brain structure & function

authors： Palande NV,Biswas S,Jadhao AG

更新日期：2011-03-01 00:00:00

abstract：:Diffusion tensor histology holds great promise for quantitative characterization of structural connectivity in mouse models of neurological and psychiatric conditions. There has been extensive study in both the clinical and preclinical domains on the complex tradeoffs between the spatial resolution, the number of samp...

journal_title：Brain structure & function

authors： Wang N,Anderson RJ,Badea A,Cofer G,Dibb R,Qi Y,Johnson GA

更新日期：2018-12-01 00:00:00

abstract：:Pigeons are classic animal models for learning, memory, and cognition. The majority of the current understanding about avian neurobiology outside of the domain of the song system has been established using pigeons. Since MRI represents an increasingly relevant tool for comparative neuroscience, a 3-dimensional MRI-bas...

journal_title：Brain structure & function

authors： Güntürkün O,Verhoye M,De Groof G,Van der Linden A

更新日期：2013-01-01 00:00:00

abstract：:The process of learning mainly depends on the ability to store new information, while the ability to retrieve this information and express appropriate behaviors are also crucial for the adaptation of individuals to environmental cues. Thereby, all three components contribute to the cognitive fitness of an individual. ...

journal_title：Brain structure & function

authors： Zhang CL,Houbaert X,Lepleux M,Deshors M,Normand E,Gambino F,Herzog E,Humeau Y

更新日期：2015-11-01 00:00:00