Abstract:
:To determine the accuracy of two-dimensional echocardiography (2-D echo) for assessment of exercise-induced wall motion abnormalities in patients with coronary artery disease, the results of stress echocardiography were compared with exercise cineventriculography. In 56 consecutive patients, biplane cineventriculography at rest and immediately after supine bicycle exercise was performed. Cross-sectional echo was obtained using the apical two- and four-chamber-views for left ventricular imaging under identical conditions. In 6 of the 56 patients 2-D echo, in 8 patients cineventriculogram, and in 2 patients both methods were of inadequate quality at rest or during exercise. Of the remaining 40 patients, 34 had coronary artery disease. Local wall motion in 360 wall segments from these patients was analyzed. In 49 segments (14%) in 24 of these patients exercise-induced ischemic wall motion abnormalities were evident during cineventriculography. Only 24 of these 49 asynergies (49%) were also recognized by 2-D echo. Using cross-sectional echocardiography, ischemia-related wall motion abnormalities were best detected septal, whereas apical asynergies were identified in only 3 of 12 segments (25%). Thus, the clinical value of exercise 2-D echo as a screening method in patients suspected of having coronary artery disease is limited and restricted to patients where excellent visualization of the left ventricular endocardium is possible.
journal_name
Clin Cardioljournal_title
Clinical cardiologyauthors
Voelker W,Jacksch R,Dittmann H,Karsch KRdoi
10.1002/clc.4960110808subject
Has Abstractpub_date
1988-08-01 00:00:00pages
547-52issue
8eissn
0160-9289issn
1932-8737journal_volume
11pub_type
杂志文章abstract:BACKGROUND:Prior studies suggest that the incidence of ventricular arrhythmias is high in patients with Fabry cardiomyopathy. This study evaluated the incidence of significant arrhythmias in a series of patients with Fabry cardiomyopathy. HYPOTHESIS:Arrhythmias are important causes of morbidity and mortality in Fabry ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.22047
更新日期:2012-12-01 00:00:00
abstract::Physical quantities and equations are used to define the laws of natural and engineering sciences. Clarity has been brought in equal measure into the the theory of physical quantities and the SI-system of units due to the basic work of Wallot and that of national and international institutions. For practical use in th...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960020410
更新日期:1979-08-01 00:00:00
abstract::Congestive heart failure (CHF) is a common manifestation of hypertension, coronary artery disease, and dilated cardiomyopathy. The Framingham study showed that the incidence of CHF increases twofold with each decade of age. The presence of CHF increases the age-adjusted death rate 5.5-fold for women and 8-fold for men...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:
更新日期:1992-09-01 00:00:00
abstract::After reviewing these published studies, I think one can conclude that in the patient population with chronic and/or paroxysmal atrial fibrillation, warfarin is beneficial and the benefits outweigh the risks. However, it is important to point out that patients at high risk for embolic disease, for example, dilated car...
journal_title:Clinical cardiology
pub_type: 社论
doi:10.1002/clc.4960160703
更新日期:1993-07-01 00:00:00
abstract::Sixteen patients with metastatic carcinoid tumors of ileal or cecal origin were studied in order to evaluate the frequency and degree of cardiac involvement in a nonselected patient group. We have also studied the correlation between plasma hormone levels (e.g., 5-hydroxytryptamine (5-HT) and substance P) and the degr...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960090104
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:Left bundle branch pacing (LBBP) has emerged as a promising pacing modality for preventing pacing induced cardiomyopathy in patients complicated with conduction abnormalities (CAs) after prosthetic valve (PV) implantation. OBJECTIVE:The present study aimed to evaluate the safety and feasibility of LBBP in t...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.23413
更新日期:2020-10-01 00:00:00
abstract::Type 2 diabetes mellitus (T2DM) is a major independent risk factor for cardiovascular disease, and diabetic dyslipidemia is a major contributor to cardiovascular risk in these patients. Here we report the rationale and design of a phase 3, double-blind study specifically designed to evaluate the lipid-lowering efficac...
journal_title:Clinical cardiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/clc.23018
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:Although nocturnal pulseoximetry is routinely performed in obstructive sleep apnea syndrome (OSAS), pulseoximetry over a 24-h period has not been studied. HYPOTHESIS:The purpose of the study was to determine whether simultaneous 24-h oxygen desaturation and electrocardiographic (ECG) recording might be used...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960210710
更新日期:1998-07-01 00:00:00
abstract::We report on a family of 4 members, all of whom have had multifocal, recurrent atrial myxomas associated with skin pigmentation, melanotic schwannomas, mucocutaneous myxomas, and tumors of the ovary and pituitary, adrenal, and thyroid glands. Immunochemistry of the myxoma cells is positive for calretinin, confirming t...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.20845
更新日期:2011-02-01 00:00:00
abstract::The use of contrast echocardiography (CE) in cardiovascular medicine has grown significantly over the last 15 years. Depending on the site of injection, contrast enhancement of the right- or left-sided cardiac chambers or myocardium now can be achieved. Contrast echocardiography can improve the evaluation of patients ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960201308
更新日期:1997-10-01 00:00:00
abstract::Cocaine-related cardiovascular events escalated during the 1980s as cocaine became purer, cheaper, and easier to obtain. Cocaine abuse is a risk factor for myocardial ischemia and/or infarction, cardiac arrhythmias, pulmonary edema, ruptured aortic aneurysm, cerebral infarction, infective endocarditis, vascular thromb...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960140626
更新日期:1991-06-01 00:00:00
abstract:BACKGROUND:The global T-inversion (GTI) electrocardiogram (ECG) is strikingly abnormal with major QTc prolongation, but with a surprisingly good prognosis by Kaplan-Meier curve. This contrasts with most significant QTc prolongations. HYPOTHESIS:This study was undertaken to ascertain QT interval dispersion (QTd) in glo...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960221012
更新日期:1999-10-01 00:00:00
abstract:BACKGROUND:Contrast-induced nephropathy (CIN) is the third cause of acute deterioration of renal function in hospitalized patients. HYPOTHESIS:The purpose of the study was to compare the efficacy of saline infusion, saline infusion plus N-acetylcysteine (NAC), and sodium bicarbonate (SB) infusion to prevent CIN in pat...
journal_title:Clinical cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1002/clc.20576
更新日期:2010-03-01 00:00:00
abstract::Paradoxical interventricular septal motion with right ventricular dilatation has been considered the hallmark of right ventricular volume overload. We report a 43-year-old woman with severe pulmonary hypertension due to pulmonary veno-occlusive disease who exhibited these echocardiographic abnormalities. Right ventric...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960081111
更新日期:1985-11-01 00:00:00
abstract:BACKGROUND:Implantable cardioverter-defibrillator (ICD) therapy for primary prevention is well established in ischemic cardiomyopathy (ICM). Data on the role of ICDs in patients with dilated cardiomyopathy (DCM) and no history of ventricular tachyarrhythmia (VT/VF) are more limited. HYPOTHESIS:DCM patients with an imp...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20949
更新日期:2011-10-01 00:00:00
abstract::Aspirin is integral in the primary and secondary prevention of coronary artery disease and acute coronary syndrome. Given the high clinical importance of aspirin in the management of coronary artery disease, much attention has been directed towards the concept of "aspirin resistance." Unfortunately, the term aspirin r...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.22031
更新日期:2012-11-01 00:00:00
abstract::This review examines the issue of preoperative cardiac evaluation from a critical point of view, based on recent medical literature. We reviewed the history of that field and focused on the American College of Cardiology and American Heart Association guidelines, which are a cornerstone in the field of cardiac patient...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960290505
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:Despite a high prevalence of hypertension in the population with CAD, there are limited data describing the clinical characteristics and treatments, as well as their interrelations in these patients. This is particularly true for black and Hispanic patients who have been underrepresented in randomized CAD tr...
journal_title:Clinical cardiology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1002/clc.4960271010
更新日期:2004-10-01 00:00:00
abstract::Based on the foregoing data it is not unreasonable to hypothesize that restoration of flow in the infarct-related artery at a later date might decrease mortality. If that is the case, then a strong argument can be made for coronary angiography in patients surviving acute myocardial infarction. Of course, the ideal way...
journal_title:Clinical cardiology
pub_type: 社论
doi:10.1002/clc.4960170405
更新日期:1994-04-01 00:00:00
abstract:BACKGROUND:Total serum transforming growth factor-beta 1 (tsTGF-β1) is increased in patients with Marfan syndrome (MFS), but it has not been assessed in thoracic aortic aneurysm and dissection (TAAD), Loeys-Dietz syndrome (LDS), and bicuspid aortic valve disease (BAVD). HYPOTHESIS:tsTGF-β1 is increased in genetic aort...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.22320
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:Atrial fibrillation (AF), a disease of the elderly, occasionally occurs at younger age. Pathophysiology of AF in younger patients is diverse, including channelopathies and cardiomyopathies. Data on the significance and complications of AF in young patients are scarce. HYPOTHESIS:Atrial fibrillation is the f...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.22516
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:Previously, the high maternal mortality in cardiac patients who became pregnant prompted the assertion: Women with an abnormal heart should not become pregnant. This long-standing notion needs to be revised today. HYPOTHESIS:The study was undertaken to ascertain the experience with a large series of pregnan...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960260308
更新日期:2003-03-01 00:00:00
abstract:BACKGROUND:Despite dual antiplatelet therapy, the rate of major adverse cardiovascular events (MACE) after percutaneous coronary intervention (PCI) remains high. Ex vivo tests of clopidogrel resistance can predict MACE after PCI. The purpose of this study is to evaluate the clinical impact of adjusting phosphorylation ...
journal_title:Clinical cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1002/clc.20884
更新日期:2011-05-01 00:00:00
abstract:BACKGROUND:Data are being accumulated on the presence of inflammatory response in patients with acute coronary syndromes. HYPOTHESIS:The study was undertaken to confirm that the adhesive state of the peripheral blood leukocytes can provide information on an inflammatory process in patients with unstable angina pectori...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960201208
更新日期:1997-12-01 00:00:00
abstract::Sinus tachycardia is the most common rhythm disturbance encountered in clinical practice. Primary sinus tachycardia without an underlying secondary cause, despite often being associated with troublesome symptoms, is often neglected leading to multiple consultations and frustration on part of both the practitioner and ...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960280603
更新日期:2005-06-01 00:00:00
abstract:BACKGROUND:Pulse pressure (PP) has recently been found to be predictive of subsequent cardiovascular, particularly coronary, events in some middle-aged and elderly populations. HYPOTHESIS:The aim of this prospective population-based study was to evaluate the roles of systolic (SBP), diastolic blood pressure (DBP), and...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960260209
更新日期:2003-02-01 00:00:00
abstract::Paravalvular regurgitation (PVR) remains one of the drawbacks of transcatheter aortic valve implantation (TAVI). Details of percutaneous closure (PCC) of PVR after TAVI remain obscure. We aimed to explore the patient characteristics, procedural details, closure devices used, and outcomes of PCC after TAVI. A systemati...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.22569
更新日期:2016-10-01 00:00:00
abstract::Data from clinical trials with benazepril suggest that the safety profile of benazepril is similar to that of other angiotensin-converting enzyme (ACE) inhibitors. Treatment-related side effects occurred in 20% of benazepril-treated patients and in 18% of patients receiving placebo. The most commonly reported side eff...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960141805
更新日期:1991-08-01 00:00:00
abstract::As I advanced through medical school at Johns Hopkins, and throughout my subsequent training, I was constantly reminded of the contributions made to medicine by our predecessors. Many of whom were at Johns Hopkins, but many were not. As I continue active involvement in the education of medical students and physicians,...
journal_title:Clinical cardiology
pub_type: 社论,历史文章
doi:10.1002/clc.20392
更新日期:2008-04-01 00:00:00
abstract::Homozygous familial hypercholesterolemia (HFH) is a very rare autosomal dominant disease characterized by accelerated severe atherosclerosis. We examined 18 patients from 9 families with HFH. The age range was 6-30 years (mean = 16 years). Male to female ratio was equal. All patients had huge, multiple tuberous xantho...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960120608
更新日期:1989-06-01 00:00:00