Abstract:
:Based on the foregoing data it is not unreasonable to hypothesize that restoration of flow in the infarct-related artery at a later date might decrease mortality. If that is the case, then a strong argument can be made for coronary angiography in patients surviving acute myocardial infarction. Of course, the ideal way to investigate this problem is to perform a large-scale prospective trial in which patients who have an occluded infarct-related artery are randomized to a revascularization procedure or continued on nonsurgical therapy. The specific management strategy for the patient with an occluded infarct-related artery after myocardial infarction depends on several features that the patient exhibits. For example, the presence or absence of LV dilatation, arrhythmias, recurrent ischemia, or clinical heart failure may dictate one form of therapy or another. There is no generic postinfarction patient with an infarct-related artery occlusion. Choices of drugs to use in these patients include the vasodilators, such as nitrates and ACE inhibitors, as well as aspirin and beta blockers. The use of calcium antagonists, chronic anticoagulants, and antiarrhythmics should have specific indications. Antithrombin agents are still experimental.
journal_name
Clin Cardioljournal_title
Clinical cardiologyauthors
doi
10.1002/clc.4960170405subject
Has Abstractpub_date
1994-04-01 00:00:00pages
167-9issue
4eissn
0160-9289issn
1932-8737journal_volume
17pub_type
社论abstract::The optimal approach to electrical cardioversion of atrial fibrillation includes appropriate patient selection, anticoagulation, careful selection and monitoring of antiarrhythmic therapy, and proper electrical cardioversion technique. The optimal technique requires the use of metal electrodes, with one electrode of a...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960170207
更新日期:1994-02-01 00:00:00
abstract:BACKGROUND AND HYPOTHESIS:In patients with stable angina pectoris, eccentric stenoses have a greater potential for dynamic changes of caliber in response to vasoactive stimuli than concentric lesions. It is not known whether in patients with coronary artery spasm the degree of coronary vasoconstriction differs in eccen...
journal_title:Clinical cardiology
pub_type: 临床试验,杂志文章
doi:10.1002/clc.4960210907
更新日期:1998-09-01 00:00:00
abstract:BACKGROUND:Atherosclerotic cardiovascular disease is prevalent among renal transplant patients. Increase in serum total cholesterol, low-density lipoprotein, and very low-density lipoprotein is common in those patients. Alterations in chylomicron metabolism, however, are also related to atherogenesis and were not studi...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960210608
更新日期:1998-06-01 00:00:00
abstract:BACKGROUND:Females with Ullrich-Turner syndrome (UTS) have typical clinical features such as short stature, ovarian failure, visible dysmorphic stigmata, and abnormalities in different organs such as kidney or heart. HYPOTHESIS:The aim of the present study was to analyze the distribution, prevalence, and relative risk...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960280209
更新日期:2005-02-01 00:00:00
abstract::Hypertrophic cardiomyopathy predisposes patients to atrial fibrillation and the development of systemic embolization. We describe a rare case of bilateral renal artery thrombosis which presented as acute renal failure requiring dialysis. The patient was successfully treated with a selective, continuous infusion of uro...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960171114
更新日期:1994-11-01 00:00:00
abstract:BACKGROUND:Cardiac contractility modulation (CCM) is an electrical-device therapy for patients with heart failure with reduced ejection fraction (HFrEF). Patients with left ventricular ejection fraction (LVEF) ≤35% also have indication for an implantable cardioverter-defibrillator (ICD), and in some cases subcutaneous ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.22919
更新日期:2018-04-01 00:00:00
abstract::During myocardial ischemia, fatty acids are the principal source of energy, increasing myocardial oxygen consumption and making a decrease in coronary blood flow less well tolerated. Increasing glucose oxidation during myocardial ischemia may improve cardiac efficiency. The pFOX inhibitors have the potential to accomp...
journal_title:Clinical cardiology
pub_type: 社论
doi:10.1002/clc.4960260402
更新日期:2003-04-01 00:00:00
abstract::Pre-infarction angina, in the absence of coronary artery disease, was found in a 62 year-old man with severe calcific aortic stenosis. After application of intraaortic balloon pump counter-pulsation, the condition was stabilized, and coronary arteriograms were safely carried out. Interestingly, an elevated right atria...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960010210
更新日期:1978-08-01 00:00:00
abstract:BACKGROUND:Variations in the apolipoprotein E (apo E) gene may predict the incidence of coronary artery disease (CAD). However, the correlation between apo E polymorphism and the severity of CAD is still unclear. HYPOTHESIS:Apolipoprotein E polymorphism can predict CAD. METHODS:Used a case-case study of 213 Chinese a...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20703
更新日期:2010-06-01 00:00:00
abstract::Antihypertensive drug therapy can lower blood pressure and prolong life, but many hypertensive patients continue to develop further risk factors and to die prematurely of heart disease. Antihypertensive drugs can also interfere with the patient's quality of life, and many are not compatible with the concomitant medica...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960181506
更新日期:1995-06-01 00:00:00
abstract::Six patients undergoing aortic valve replacement had rare or unusual causes of isolated, pure aortic regurgitation. Two patients had congenitally bicuspid aortic valves with a false commissure (raphe) displaced to the aortic wall ("tethered bicuspid aortic valve"), two had floppy aortic valves, one had a congenital qu...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960130812
更新日期:1990-08-01 00:00:00
abstract::An 81-year-old man presented with a large, infected right atrial thrombus that was refractory to anticoagulants and several courses of antibiotics. The risk of surgical removal of the thrombus, which was associated with a pacemaker electrode, was considered prohibitive. The patient was treated for 7 days with low-dose...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4950250709
更新日期:2002-07-01 00:00:00
abstract::Vasodilating prostaglandins may be increased in patients with chronic congestive heart failure (CHF) to balance out the effects of vasoconstricting forces. Significant increases in plasma levels of bicycloprostaglandin E2 metabolite (PGEm), a chemically stable degradation product of the vasodilating prostaglandin E2, ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960120206
更新日期:1989-02-01 00:00:00
abstract:BACKGROUND:Coronary artery disease (CAD) risk is not fully revealed by traditional risk factors. Identification of a simple, noninvasive tool that allows for detection of high-risk CAD patients and can be applied in large populations and clinical settings would prove valuable. HYPOTHESIS:We sought to test the hypothes...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20705
更新日期:2010-02-01 00:00:00
abstract::Rocky Mountain spotted fever is a serious infectious disease that continues to occur with increasing incidence in various areas of the United States. A high case-fatality ratio (11%) persists in spite of availability of adequate chemotherapeutic agents, and the cardiac involvement may play an important role in the fin...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960061006
更新日期:1983-10-01 00:00:00
abstract::Thrombotic obstruction of aortic bioprostheses is rare. Few cases have been reported involving the use of the Carpentier-Edwards (CE) prosthesis, the Hancock bioprosthesis, or the Medtronic Intact porcine valve. Thrombolytic therapy for mechanical valve thrombosis has been used frequently even though it is known to ca...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960160215
更新日期:1993-02-01 00:00:00
abstract::Transient left ventricular (LV) apical ballooning and normal epicardial coronary arteries are the hallmarks of Takotsubo cardiomyopathy. The syndrome is often triggered by emotional or physiologic stress, and its pathogenesis is poorly understood. Current proposals focus on elevated cathecolamines in association with ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20065
更新日期:2007-07-01 00:00:00
abstract:BACKGROUND:There are no studies in the literature related to the effect of beta blockers (BB) on changes in C-reactive protein (CRP) levels after percutaneous coronary intervention (PCI). HYPOTHESIS:We designed a prospective randomized study to investigate the impact of BB therapy on CRP in patients who underwent elec...
journal_title:Clinical cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/clc.4960280509
更新日期:2005-05-01 00:00:00
abstract::A 55-year-old Caucasian woman suddenly developed substernal chest pain at rest accompanied by pallor, diaphoresis, nausea, and vomiting. Physical examination was otherwise unremarkable. The resting ECG showed T-wave inversion in all anterior leads which returned to normal 24 h after the onset of the symptoms. The pain...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960100614
更新日期:1987-06-01 00:00:00
abstract:BACKGROUND AND HYPOTHESIS:Although it is well established that diabetes mellitus (DM) induces more severe coronary artery disease (CAD), it is not known whether it contributes to the development of coronary collateral circulation. The present study examines coronary collateral circulation in diabetic and nondiabetic pa...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960220706
更新日期:1999-07-01 00:00:00
abstract::The aim of this study was to assess whether drinking social amounts of alcohol impairs myocardial contractility in normal humans. To that end, 17 healthy volunteers performed isometric handgrip exercise before and 60 minutes after an intake of 1 g/kg body weight of ethanol within 60 minutes. Left ventricular M-mode ec...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960060302
更新日期:1983-03-01 00:00:00
abstract:BACKGROUND:In clinical cardiology, heart rate variability is a putative index of autonomic cardiovascular function. Signs of reduced vagal activity are not only associated with an enhanced risk of sudden cardiac death, but such impaired heart rate variability became a new predictor of sudden cardiac death and other mor...
journal_title:Clinical cardiology
pub_type: 临床试验,杂志文章
doi:10.1002/clc.4960200710
更新日期:1997-07-01 00:00:00
abstract:BACKGROUND:When used in appropriately selected heart failure (HF) patients, cardiac resynchronization therapy (CRT) reduces mortality and hospitalization. It is not understood whether CRT implantation during hospitalization for HF is associated with similar benefits. HYPOTHESIS:Timing of CRT implantation relative to h...
journal_title:Clinical cardiology
pub_type: 杂志文章,多中心研究
doi:10.1002/clc.23135
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Oxidized low-density lipoprotein (oxLDL) not only plays an important role in plaque formation, but also impairs the endothelium-dependent relaxation. Constrictive remodeling rather than intimal hyperplasia mainly contributes to restenosis after balloon angioplasty. Probucol (powerful antioxidant) reduced res...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960260107
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:Previously, the high maternal mortality in cardiac patients who became pregnant prompted the assertion: Women with an abnormal heart should not become pregnant. This long-standing notion needs to be revised today. HYPOTHESIS:The study was undertaken to ascertain the experience with a large series of pregnan...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960260308
更新日期:2003-03-01 00:00:00
abstract::Left ventricular systolic dysfunction (LVSD) and clinical heart failure are common complications of acute myocardial infarction (AMI) and result in substantially increased mortality and morbidity. Evidence-based cardiovascular protective therapies, including angiotensin-converting enzyme inhibitors, beta blockers, ant...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960290103
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Cardiac troponin I (cTnI), N-terminal pro-B-type natriuretic peptide (NT-proBNP) and high-sensitivity C-reactive protein (hsCRP) each predict adverse cardiac events in chronic heart failure (CHF). However, little is known about the utility of these novel biomarkers of CHF in combination. HYPOTHESIS:: We hyp...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20171
更新日期:2007-08-01 00:00:00
abstract::We describe two patients in whom spontaneous angina following acute myocardial infarction (postinfarction angina caused by coronary artery spasm) and worsening angina were successfully eliminated after clinical dosage of oral diltiazem, while marked sinus node suppression developed and temporary pacing was performed. ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960071110
更新日期:1984-11-01 00:00:00
abstract::Physicians previously perceived heart disease to be a man's disease; yet, since 1984, more women have died of ischemic heart disease. Because women who develop obstructive coronary heart disease and heart failure tend to do so 10 years later than men, cardiology clinical trials that use arbitrary age cutoffs or exclus...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.22907
更新日期:2018-02-01 00:00:00
abstract::After reviewing these published studies, I think one can conclude that in the patient population with chronic and/or paroxysmal atrial fibrillation, warfarin is beneficial and the benefits outweigh the risks. However, it is important to point out that patients at high risk for embolic disease, for example, dilated car...
journal_title:Clinical cardiology
pub_type: 社论
doi:10.1002/clc.4960160703
更新日期:1993-07-01 00:00:00