Abstract:
BACKGROUND:Previously, the high maternal mortality in cardiac patients who became pregnant prompted the assertion: Women with an abnormal heart should not become pregnant. This long-standing notion needs to be revised today. HYPOTHESIS:The study was undertaken to ascertain the experience with a large series of pregnant women with cardiac disease cared for in the same referral center. METHODS:From 1989 to 1999, 1,000 pregnant women with heart disease were followed by the same clinical and obstetric team. The cardiac diseases included rheumatic heart disease (55.7%), congenital heart disease (19.1%), Chagas' disease (8.5%), cardiac arrhythmias (5.1%), cardiomyopathies (4.3%), and others (7.3%). RESULTS:Of the pregnant women studied, 765 (76.5%) experienced no cardiovascular events during the study; 235 (23.5%) patients had the following cardiovascular complications: congestive heart failure (12.3%), cardiac arrhythmias (6%), thromboembolism (1.9%), angina (1.4%), hypoxemia (0.7%), infective endocarditis (0.5%), and other complications (0.7%). Clinical treatment allowed adequate management in 161 (68.8%) patients; however, 46 (19.6%) patients underwent interventional procedures because of refractory complications. The general maternal mortality rate was 2.7%. Of the 915 (91.5%) infants who were discharged, 119 (13%) were premature. CONCLUSION:Pregnancy in women with heart disease is still associated with considerable morbidity and mortality rates, which strongly correlate to maternal underlying disease. Strict prenatal care and early risk stratification during gestation are fundamental measures to improve the prognosis of pregnancy in women with heart disease.
journal_name
Clin Cardioljournal_title
Clinical cardiologyauthors
Avila WS,Rossi EG,Ramires JA,Grinberg M,Bortolotto MR,Zugaib M,da Luz PLdoi
10.1002/clc.4960260308subject
Has Abstractpub_date
2003-03-01 00:00:00pages
135-42issue
3eissn
0160-9289issn
1932-8737journal_volume
26pub_type
杂志文章abstract::The use of contrast echocardiography (CE) in cardiovascular medicine has grown significantly over the last 15 years. Depending on the site of injection, contrast enhancement of the right- or left-sided cardiac chambers or myocardium now can be achieved. Contrast echocardiography can improve the evaluation of patients ...
journal_title:Clinical cardiology
pub_type: 杂志文章
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journal_title:Clinical cardiology
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journal_title:Clinical cardiology
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journal_title:Clinical cardiology
pub_type: 杂志文章,随机对照试验
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更新日期:2012-04-01 00:00:00
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journal_title:Clinical cardiology
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doi:10.1002/clc.4960130911
更新日期:1990-09-01 00:00:00
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更新日期:2017-04-01 00:00:00
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journal_title:Clinical cardiology
pub_type: 临床试验,杂志文章
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journal_title:Clinical cardiology
pub_type: 杂志文章,评审
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journal_title:Clinical cardiology
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doi:10.1002/clc.4960061206
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