Abstract:
:Atrial natriuretic peptide (ANP) levels were measured prior to and at 1 and 5 minutes postcontrast left ventriculography with an ionic contrast agent (diatrizoate), and a nonionic agent (iopamidol) and the results were compared. Since ionic contrast agents have been found to cause an increase in left ventricular end-diastolic pressure (LVEDP) and nonionic agents have been found to have less of an effect on LVEDP, we investigated the response of ANP levels, which have been found to increase secondary to increased LVEDP (atrial pressure), with both agents. A group of 38 patients who were scheduled for left heart catheterization for suspected coronary artery disease was included (19 in each group) and blood samples for ANP levels were drawn from the left ventricles. At the same time, heart rate, LVEDP, and left ventricular systolic pressure (LVSP) were also measured. It was found that the LVEDP increased significantly for both agents at 1 minute postventriculography, but no further change occurred at 5 min. Heart rate increased significantly in the diatrizoate group at 1 minute with a return of heart rate to preventriculography levels at 5 min, while the ANP level and LVSP remained unchanged at 1 minute postventriculography with both agents but increased significantly at 5 min in the diatrizoate group only. This difference in ANP response is not correlated with the LVEDP. The response of ANP may be related to heart rate and/or LVSP.
journal_name
Clin Cardioljournal_title
Clinical cardiologyauthors
Salvucci TJ,Roman C,Cha SD,Maranhao Vdoi
10.1002/clc.4960130911subject
Has Abstractpub_date
1990-09-01 00:00:00pages
644-8issue
9eissn
0160-9289issn
1932-8737journal_volume
13pub_type
杂志文章abstract:BACKGROUND:Therapeutic angiogenesis, if combined with primary percutaneous transluminal coronary angioplasty or stent placement, could improve the outcome of patients suffering from multifocal coronary disease. HYPOTHESIS:Because of the concern that angiogenic growth factors might promote restenosis, we studied the ef...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960250606
更新日期:2002-06-01 00:00:00
abstract::In this editorial, I would like to share some thoughts about clinical studies, including value and limitations using as an example a recently published randomized clinical trial. Randomized and non-randomized clinical trials, epidemiologic studies, and registries guide our clinical practice. They are good but not perf...
journal_title:Clinical cardiology
pub_type: 社论
doi:10.1002/clc.20598
更新日期:2009-04-01 00:00:00
abstract::Malignant lymphoma commonly involves the heart. Previous studies have found cardiac metastases in up to 20% of patients dying with lymphoma. Cardiac signs and symptoms of lymphoma are relatively rare, however, and in most cases, the diagnosis is made either postmortem or too late to affect the clinical course. This re...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960190326
更新日期:1996-03-01 00:00:00
abstract:BACKGROUND:Successful smoking cessation in stroke and coronary artery disease (CAD) patients is important, as smoking contributes to significant morbidity and mortality. The American Heart Association developed Get With The Guidelines (GWTG) to improve compliance with national guideline recommendations for cardiovascul...
journal_title:Clinical cardiology
pub_type: 杂志文章,多中心研究
doi:10.1002/clc.22023
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Exercise-induced dyspnea is a frequent feature in patients with hyperthyroidism. HYPOTHESIS:Data from clinical studies to elucidate the origin of this symptom are lacking. In the current study, we examined the hemodynamic and oxygenation responses to exercise and beta-adrenergic blockade in patients with hy...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960270707
更新日期:2004-07-01 00:00:00
abstract:BACKGROUND:Inflammatory process plays an important role in the pathogenesis of acute coronary syndromes. HYPOTHESIS:The study was undertaken to evaluate whether admission levels of C-reactive protein (CRP), fibrinogen, interleukin-6 (IL-6). and macrophage colony stimulating factor (MCSF) can predict short-term prognos...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960251106
更新日期:2002-11-01 00:00:00
abstract:BACKGROUND:Variations in the apolipoprotein E (apo E) gene may predict the incidence of coronary artery disease (CAD). However, the correlation between apo E polymorphism and the severity of CAD is still unclear. HYPOTHESIS:Apolipoprotein E polymorphism can predict CAD. METHODS:Used a case-case study of 213 Chinese a...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20703
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:Echocardiographic evidence of diastolic dysfunction has been demonstrated during acute cigarette smoking in patients with coronary artery disease. Similar studies in healthy patients have shown conflicting results. Furthermore, it is unclear whether nicotine or some other cigarette-related substance is respo...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960290205
更新日期:2006-02-01 00:00:00
abstract:BACKGROUND:Early recurrence of atrial fibrillation (ERAF) after catheter ablation is common and has been thoroughly studied. However, very late recurrence of atrial fibrillation (VLRAF) is rarely researched, and its characteristics have not been determined. HYPOTHESIS:The aim of this study was to investigate the clini...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20340
更新日期:2008-10-01 00:00:00
abstract::The aim of this study was to assess whether drinking social amounts of alcohol impairs myocardial contractility in normal humans. To that end, 17 healthy volunteers performed isometric handgrip exercise before and 60 minutes after an intake of 1 g/kg body weight of ethanol within 60 minutes. Left ventricular M-mode ec...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960060302
更新日期:1983-03-01 00:00:00
abstract:BACKGROUND:Guidelines suggest that "upstream" P2Y12 receptor antagonists should be considered in patients with non-ST-segment elevation acute coronary syndromes (NSTE-ACS). HYPOTHESIS:Early use of ticagrelor in patients managed with an invasive strategy would be more effective than clopidogrel because of its more rapi...
journal_title:Clinical cardiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/clc.22733
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:Hospitalized medically ill patients are at greater risk for venous thromboembolism (VTE). Although pharmacologic prophylaxis regimens have reduced VTE risk in medically ill patients, associations with early postdischarge adverse clinical outcomes among patients with heart failure are unknown. HYPOTHESIS:We ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20986
更新日期:2011-11-01 00:00:00
abstract::Rapid assessment of patients presenting with acute chest pain is essential, in order to distinguish between those who have a life-threatening condition, such as myocardial infarction or unstable angina, and the substantial proportion who do not have an acute coronary syndrome. It is thus of vital importance that relia...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960231306
更新日期:2000-01-01 00:00:00
abstract::The realization that cardiovascular morbidity and mortality increases in patients with mild elevation of either systolic or diastolic blood pressure has led to a consideration to treat millions of patients with mild diastolic or isolated systolic hypertension. The cost of administering a successful antihypertensive tr...
journal_title:Clinical cardiology
pub_type: 临床试验,杂志文章
doi:10.1002/clc.4960060101
更新日期:1983-01-01 00:00:00
abstract::A 51-year-old female with a two-year history of palpitations associated with swallowing was evaluated by intracardiac electrophysiologic studies. Intracardiac recordings documented the presence of an ectopic left atrial focus induced by swallowing with no evidence of accessory pathway conduction. Gastrointestinal eval...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960110117
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND:Therapeutic hypothermia improves survival for selected patients who remain comatose after cardiac arrest. Hypothermia triggers changes in electrocardiographic (ECG) parameters; however, the association of these changes to in-hospital mortality remains unclear. HYPOTHESIS:QT interval changes induced by thera...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.22224
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:Diabetes mellitus (DM) is well established as a short-term prognostic indicator after myocardial infarction (MI), but little long-term data are available. HYPOTHESIS:The objective of the study was to assess the impact of DM and other patient characteristics at baseline on long-term mortality after acute MI....
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20776
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND AND HYPOTHESIS:Previous research has failed to document temporal changes in epinephrine levels in patients with neurally mediated syncope associated with exercise. The purpose of this study was to investigate the role of circulatory catecholamines in exercise-induced neurally mediated syncope, specifically f...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::Left ventricular wall motion abnormalities, aneurysm formation, and progression to global hypokinesis have been described in patients with myocarditis and in patients with hypertrophic cardiomyopathy. We document a case of reversible aneurysm formation, cardiogenic shock, and complete recovery in a patient with myocar...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960160317
更新日期:1993-03-01 00:00:00
abstract:BACKGROUND:Contrast-induced nephropathy (CIN) is the third cause of acute deterioration of renal function in hospitalized patients. HYPOTHESIS:The purpose of the study was to compare the efficacy of saline infusion, saline infusion plus N-acetylcysteine (NAC), and sodium bicarbonate (SB) infusion to prevent CIN in pat...
journal_title:Clinical cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1002/clc.20576
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:In animal models, pretreatment with angiotensin-converting enzyme inhibitor (ACEI) can reduce no-reflow. In the present study, we investigated whether pretreatment with ACEI may prevent no-reflow in patients who underwent primary coronary intervention for AMI. METHOD AND RESULTS:A total of 259 consecutive p...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20060
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND:While depressed left ventricular ejection fraction is clearly associated with poor long-term outcome in heart failure (HF), the effect of ejection fraction on short-term outcomes and resource utilization following hospitalization for HF remains unclear. HYPOTHESIS:We evaluated the independent effect of depr...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960220306
更新日期:1999-03-01 00:00:00
abstract:BACKGROUND:Takotsubo cardiomyopathy (TCM) is characterized by systolic ballooning of the left ventricular apex. It is triggered by emotional or physical stress, but the exact mechanism through which stress leads to TCM is not known. HYPOTHESIS:Coronary microvessel apoptosis is the missing link between stress and TCM. ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20777
更新日期:2010-06-01 00:00:00
abstract::A space-occupying mass of the right atrium was found by two-dimensional echocardiography and angiography in a 68-year-old woman whose clinical diagnosis indicated multiple pulmonary emboli. Since right heart myxomas frequently cause pulmonary thromboembolism, the patient was initially diagnosed by noninvasive and inva...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960070113
更新日期:1984-01-01 00:00:00
abstract:BACKGROUND:C-reactive protein (CRP) and myeloperoxidase (MPO) are involved in the pathogenesis of atherosclerosis, mainly during periods of instabilization. This study aims to test the hypothesis that patients with acute coronary syndrome (ACS) maintain a persistent inflammatory state, and that this is associated with ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20462
更新日期:2009-11-01 00:00:00
abstract:BACKGROUND:The poor clinical outcome in acute myocardial infarction (AMI) patients undergoing primary percutaneous coronary intervention (PCI) has been attributed to myocardial ischemia-reperfusion injury (MIRI). OBJECTIVE:This study aimed to identify the predictive factors of MIRI during PCI in Chinese AMI patients w...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20294
更新日期:2009-03-01 00:00:00
abstract::In order to assess the diagnostic value of dipyridamole (D) testing, we studied the responses of 34 patients with chest pain and 10 normal subjects. Blood pressure and 12-lead ECG were recorded during and after intravenous infusion of 0.6 mg/kg dipyridamole for 10 minutes. Coronary arteriography and maximal or symptom...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960050402
更新日期:1982-04-01 00:00:00
abstract:BACKGROUND:Chronic heart failure (CHF) is associated with an increased risk of thrombosis and thromboembolic events, including stroke and venous thromboembolism. which may be related to a prothrombotic or hypercoagulable state. Acute vigorous exercise has been associated with activation of hemostasis, and this risk may...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960241107
更新日期:2001-11-01 00:00:00
abstract:BACKGROUND:Transesophageal echocardiography (TEE) has been used to identify the potential risk for cardiogenic embolism in patients with atrial fibrillation (AF). However, ischemic stroke in patients with AF is not always attributable to embolism. Identification of the risk of embolic versus atherothrombotic stroke sho...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960230710
更新日期:2000-07-01 00:00:00
abstract:BACKGROUND:Cardiac troponin T elevation after coronary intervention has been demonstrated to be associated with the prognosis of coronary artery disease (CAD). However, there were few studies about comprehensive risk factors analysis of troponin T elevation after elective drug-eluting stent (DES) implantation. HYPOTHE...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20973
更新日期:2011-12-01 00:00:00