Abstract:
:Data from clinical trials with benazepril suggest that the safety profile of benazepril is similar to that of other angiotensin-converting enzyme (ACE) inhibitors. Treatment-related side effects occurred in 20% of benazepril-treated patients and in 18% of patients receiving placebo. The most commonly reported side effects with benazepril were headache, dizziness, and fatigue. The incidence of side effects was not affected by the degree of hypertension, age, gender, race, dosage, or the degree of renal impairment. Side effects believed to be related to the pharmacologic action of ACE inhibitors as a class include symptomatic hypotension, which occurred at a relatively low rate with benazepril, and hyperkalemia and elevation of serum creatinine, which occurred to the same extent with benazepril as has been noted with other ACE inhibitors. The mechanism of cough as an ACE inhibitor side effect is unknown; the incidence was similar to that with other ACE inhibitors. Rash and taste disturbance have occurred rarely with benazepril. The incidence of neutropenia and of proteinuria was the same in both the benazepril and placebo groups. Renal failure in hypertensive patients treated with benazepril has not been reported. Overall, benazepril is generally well tolerated by hypertensive patients. The incidence of most side effects is comparable to that with other ACE inhibitors and placebo.
journal_name
Clin Cardioljournal_title
Clinical cardiologyauthors
MacNab M,Mallows Sdoi
10.1002/clc.4960141805subject
Has Abstractpub_date
1991-08-01 00:00:00pages
IV33-7; discussion IV51-5issue
8 Suppl 4eissn
0160-9289issn
1932-8737journal_volume
14pub_type
杂志文章,评审abstract::Many patients with coronary artery disease treated by percutaneous transluminal coronary angioplasty (PTCA) have a history of previous myocardial injury resulting in a reduced left ventricular ejection fraction (EF). The effects of successful PTCA on myocardial perfusion and left ventricular function in these patients...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960120504
更新日期:1989-05-01 00:00:00
abstract::Thirty-eight patients treated by atrial pacing were divided into three groups (Group I, patients with neither coronary stenosis nor anginal pain during pacing; Group II, patients with no coronary stenosis but having anginal pain during pacing; Group III, patients with coronary stenosis). The concentrations of adenosin...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960120203
更新日期:1989-02-01 00:00:00
abstract::In 2002, coronary angiography is the only way to assess precisely the combination of proximal stenoses, distal target vessels, collaterals, microcirculation, and TIMI antegrade flow. At the time of coronary angiography, global LV function is best determined using biplane ventriculography in order to correlate wall mot...
journal_title:Clinical cardiology
pub_type: 社论
doi:10.1002/clc.4950250802
更新日期:2002-08-01 00:00:00
abstract:BACKGROUND:Inadequate cardiovascular disease (CVD) knowledge has been cited to account for the imperfect decline in CVD among women over the last 2 decades. HYPOTHESIS:Due to concerns that at-risk women might not know the leading cause of death or symptoms of a heart attack, our goal was to assess the relationship bet...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20992
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND AND HYPOTHESIS:Genetic influence on development of athlete's heart is uncertain. This study investigated whether angiotensin-converting enzyme (ACE) gene polymorphism influenced development of athlete's heart. METHODS:Forty-three participants in a 100-km ultramarathon were classified on the basis of ACE gen...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960230814
更新日期:2000-08-01 00:00:00
abstract::Nonpharmacologic therapies for patients with sustained ventricular tachycardia have been necessitated by the low frequency of drug-responsive patients. These nonpharmacologic therapies include antitachycardia pacemakers, low-energy cardioverters, defibrillators, surgery and, for the present, catheter ablation. Antitac...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:
更新日期:1988-03-01 00:00:00
abstract::This work attempted to study the segmental wall motion on left ventriculograms, in terms of segmental shortening, velocity of segmental shortening, and temporal sequences of various events in systole as well as in diastole. The ability of such a method to characterize patterns of normal regional wall motion and to det...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960090201
更新日期:1986-02-01 00:00:00
abstract::Various types of pulmonary venous return abnormalities have been described in the literature. This report presents a case in which a 4-h-old neonate presented with cyanotic heart disease and respiratory distress. This neonate was subsequently shown to have complete absence of the pulmonary veins (CAPV), a previously u...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960110415
更新日期:1988-04-01 00:00:00
abstract:BACKGROUND:We sought to determine whether lifestyle modifications are associated with high-density lipoprotein cholesterol (HDL-C) change in a cohort with long-term follow-up. HYPOTHESIS:Changes in alcohol consumption, smoking, or body mass index (BMI) are associated with within-individual changes in HDL-C. METHODS:W...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.21978
更新日期:2012-01-01 00:00:00
abstract::Until recently, instrumenting the pericardium was possible only when a pericardial effusion is present or by surgical exposure of the pericardium. Techniques are now being developed to instrument the normal pericardium. This development will allow clinicians and investigators to study pericardial fluid in health and i...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960221304
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Myocardial bridging (MB) has been associated with cardiac events. Whether coronary spasm is one factor contributing to those events is unknown. HYPOTHESIS:This study investigated whether the likelihood of coronary spasm is increased in patients with MB. METHODS:A spasm-provocation test was performed by inf...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4950260806
更新日期:2003-08-01 00:00:00
abstract:BACKGROUND:The electrocardiogram (ECG) is valuable for the identification of prior myocardial infarction (MI) in individuals participating in epidemiologic studies or undergoing screening examinations. Although the Minnesota Code, a set of criteria for the interpretation of ECGs in such situations, is commonly used to ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960270212
更新日期:2004-02-01 00:00:00
abstract::Antithrombotic and thrombolytic therapies confer clear net benefits in the treatment of acute myocardial infarction (AMI). Antithrombotic therapy with aspirin yields conclusive reductions in vascular mortality as well as reinfarction and stroke and should be administered to all patients with suspected AMI. There is pr...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960201408
更新日期:1997-11-01 00:00:00
abstract:BACKGROUND/HYPOTHESIS:SMARTWOMAN™ was designed to develop and assess the feasibility of a smartphone app to control cardiovascular risk factors in vulnerable diabetic women. METHODS:Fourteen African-American women with diabetes and without known cardiovascular disease were enrolled. A weight-scale, glucometer, sphygmo...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.23124
更新日期:2019-02-01 00:00:00
abstract::Relatively little information is available concerning the incidence of sudden death in athletes in the United States. The present study provides annual incidence rates of sudden athletic deaths in Marion County, Indiana, home of Indianapolis, the "amateur sports capital of the world." The overall incidence was 0.04% (...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960151111
更新日期:1992-11-01 00:00:00
abstract:BACKGROUND:Internal cardioversion of atrial fibrillation with direct current energy has become an increasingly employed technique for patients who fail external cardioversion. HYPOTHESIS:The purpose of this study was to determine whether internal cardioversion could be avoided by careful attention to cardioversion tec...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960240716
更新日期:2001-07-01 00:00:00
abstract:BACKGROUND:Atherosclerosis is widely accepted as a chronic inflammatory disease. Research paid much attention to sensitive specific serum biomarkers for vulnerable plaques. The markers not only serve as diagnostic tools for the identification of patients with acute coronary syndrome (ACS), but also help us to identify ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20254
更新日期:2008-09-01 00:00:00
abstract::His-bundle ablation is a very effective method to control drug-refractory supraventricular arrhythmias. We present a 69-year-old woman with paroxysmal atrial fibrillation, in whom several attempts of unipolar and bipolar His-bundle ablation were ineffective. Ultimately a stable 2/1 atrioventricular block was induced w...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960100516
更新日期:1987-05-01 00:00:00
abstract::Cross-sectional echocardiography was performed on two patients with mitral regurgitation in whom M-mode echocardiographic findings were not specific for the etiology of mitral regurgitation. In one patient, flail motion of the free edge of the anterior mitral leaflet into the left atrium was demonstrated only by cross...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960010206
更新日期:1978-08-01 00:00:00
abstract:BACKGROUND:Successful smoking cessation in stroke and coronary artery disease (CAD) patients is important, as smoking contributes to significant morbidity and mortality. The American Heart Association developed Get With The Guidelines (GWTG) to improve compliance with national guideline recommendations for cardiovascul...
journal_title:Clinical cardiology
pub_type: 杂志文章,多中心研究
doi:10.1002/clc.22023
更新日期:2012-01-01 00:00:00
abstract::Two recent observations based on echocardiographic studies in large population-based studies may have far-reaching implications: The concentric form of left ventricular hypertrophy emerges prominently in white Framingham (MA) men aged 40-49 years, and ten years later in white Framingham women. This parallels the patte...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960121307
更新日期:1989-12-01 00:00:00
abstract::The use of contrast echocardiography (CE) in cardiovascular medicine has grown significantly over the last 15 years. Depending on the site of injection, contrast enhancement of the right- or left-sided cardiac chambers or myocardium now can be achieved. Contrast echocardiography can improve the evaluation of patients ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960201308
更新日期:1997-10-01 00:00:00
abstract::A space-occupying mass of the right atrium was found by two-dimensional echocardiography and angiography in a 68-year-old woman whose clinical diagnosis indicated multiple pulmonary emboli. Since right heart myxomas frequently cause pulmonary thromboembolism, the patient was initially diagnosed by noninvasive and inva...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960070113
更新日期:1984-01-01 00:00:00
abstract::Full recovery occurred after 15 months of severe congestive heart failure in a patient with peripartum cardiomyopathy. Clinical improvement was noted when propranolol was added to conventional therapy. ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960030211
更新日期:1980-08-01 00:00:00
abstract::Type II heparin-induced thrombocytopenia (HIT) is a potentially severe adverse effect of heparin treatment triggered by an immune response. Although most cases occur in patients receiving unfractioned heparin, HIT can also arise after low-molecular-weight heparin (LMWH). We report a case of HIT in a postoperative orth...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20546
更新日期:2010-02-01 00:00:00
abstract::The case of a 73-year-old man with right heart failure and systolic and diastolic murmur at the fourth left intercostal space is described. There was a history of rheumatic fever. Two-dimensional echocardiography showed rheumatic change of the tricuspid valve with giant right atrium and ventricle, which was confirmed ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960090710
更新日期:1986-07-01 00:00:00
abstract::A case of aortic ball valve prosthesis malfunction is described in which the poppet became alternately stuck in the open and closed position. The patient experienced chest pain followed by pulmonary edema and cardiac arrest. Malfunction of prosthetic valve was diagnosed on echocardiogram and cardiopulmonary resuscitat...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960051105
更新日期:1982-11-01 00:00:00
abstract::Six patients undergoing aortic valve replacement had rare or unusual causes of isolated, pure aortic regurgitation. Two patients had congenitally bicuspid aortic valves with a false commissure (raphe) displaced to the aortic wall ("tethered bicuspid aortic valve"), two had floppy aortic valves, one had a congenital qu...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960130812
更新日期:1990-08-01 00:00:00
abstract:BACKGROUD:The association between underlying comorbidities and cardiac injury and the prognosis in coronavirus disease 2019 (COVID-19) patients was assessed in this study. HYPOTHESIS:The underlying comorbidities and cardiac injury may be associated with the prognosis in COVID-19 patients. METHODS:A systematic search ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.23465
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Metabolic syndrome (MS) and diabetes mellitus (DM) are risk factors for cardiovascular diseases in general population. However, there was a paucity of studies investigating their impact in primary glomerular diseases (PGD). HYPOTHESIS:MS and concomitant DM are associated with higher risk of cardiovascular c...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.23388
更新日期:2020-09-01 00:00:00