Abstract:
:Type II heparin-induced thrombocytopenia (HIT) is a potentially severe adverse effect of heparin treatment triggered by an immune response. Although most cases occur in patients receiving unfractioned heparin, HIT can also arise after low-molecular-weight heparin (LMWH). We report a case of HIT in a postoperative orthopedic 75-year-old woman in treatment with LMWH (nadroparin) complicated by pulmonary embolism and treated successfully with recombinant hirudin. Early recognition and proper treatment are fundamental for the management of this life-threatening disorder.
journal_name
Clin Cardioljournal_title
Clinical cardiologyauthors
Mumoli N,Cei Mdoi
10.1002/clc.20546subject
Has Abstractpub_date
2010-02-01 00:00:00pages
E65-7issue
2eissn
0160-9289issn
1932-8737journal_volume
33pub_type
杂志文章abstract::To determine whether exercise-induced ischemia impairs left ventricular diastolic filling in the postischemic period in humans, 101 men (mean age 57 +/- 10 years) were studied before and 2 h after a symptom-limited thallium-201 tomographic treadmill with pulsed Doppler echocardiography of mitral valve inflow. In the p...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960150409
更新日期:1992-04-01 00:00:00
abstract:BACKGROUND:We previously reported that an index of afterload-related left ventricular diastolic function, operant diastolic elastance (Ed)/effective arterial elastance (Ea) = E/e'/(0.9 × systolic blood pressure), was significantly higher in elderly hypertensive women. We aimed to determine sex-related differences in th...
journal_title:Clinical cardiology
pub_type: 杂志文章,多中心研究
doi:10.1002/clc.23073
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:Pulse pressure (PP) has recently been found to be predictive of subsequent cardiovascular, particularly coronary, events in some middle-aged and elderly populations. HYPOTHESIS:The aim of this prospective population-based study was to evaluate the roles of systolic (SBP), diastolic blood pressure (DBP), and...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960260209
更新日期:2003-02-01 00:00:00
abstract::Heart transplantation is the only curative therapy for chronic heart failure, and it plays an important role in the treatment of chronic heart failure with a survival rate of approximately 50% of all patients after 10 years. This has to be kept in mind when alternative therapies enter into our daily routine in treatin...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.22124
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:Although nocturnal pulseoximetry is routinely performed in obstructive sleep apnea syndrome (OSAS), pulseoximetry over a 24-h period has not been studied. HYPOTHESIS:The purpose of the study was to determine whether simultaneous 24-h oxygen desaturation and electrocardiographic (ECG) recording might be used...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960210710
更新日期:1998-07-01 00:00:00
abstract::The incidence of inadvertent permanent ventricular pacing from the coronary vein is not known. In a retrospective analysis of 69 patients in whom transvenous pacemakers were implanted between 1979 and 1986, 12 patients were discovered to have right bundle-branch block pattern to the paced complexes on electrocardiogra...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960120508
更新日期:1989-05-01 00:00:00
abstract::Malignant lymphoma commonly involves the heart. Previous studies have found cardiac metastases in up to 20% of patients dying with lymphoma. Cardiac signs and symptoms of lymphoma are relatively rare, however, and in most cases, the diagnosis is made either postmortem or too late to affect the clinical course. This re...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960190326
更新日期:1996-03-01 00:00:00
abstract::To assess the immediate and long-term effects of exercise on factors regulating blood flow, we measured plasma viscosity (eta p) and plasma renin activity (PRA) in 17 trained runners and 16 sedentary healthy subjects before and 10 min after graded treadmill exercise. Resting eta p was lower in runners primarily becaus...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960040405
更新日期:1981-07-01 00:00:00
abstract::Although physical fitness is a powerful prognostic marker in clinical medicine, most cardiovascular population-based studies do not have a direct measurement of cardiorespiratory fitness. In line with the call from the National Heart Lung and Blood Institute for innovative, low-cost, epidemiologic studies leveraging e...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.22302
更新日期:2014-08-01 00:00:00
abstract::Lipoprotein(a) [Lp(a)] is independently associated with atherosclerotic cardiovascular disease and calcific aortic valve stenosis. Elevated Lp(a) affects approximately one in five individuals and meaningfully contributes to the residual cardiovascular risk in individuals with otherwise well-controlled risk factors. Wi...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.23456
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Early reperfusion improves left ventricular (LV) function and survival after acute myocardial infarction (MI). Thrombolytic therapy achieves early patency of the infarct artery in about two-thirds of patients. In nearly half of the remaining patients, in whom early reperfusion was not achieved with thromboly...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960221206
更新日期:1999-12-01 00:00:00
abstract::To assess right ventricular (RV) diastolic filling in coronary artery disease (CAD), with special reference to the involved lesions of the coronary arteries and left ventricular (LV) systolic function, gated radionuclide ventriculography was performed at rest in 106 patients with single-vessel CAD. Based on the site o...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960161112
更新日期:1993-11-01 00:00:00
abstract:BACKGROUND:Hypercholesterolemia is a risk factor for coronary artery disease, yet is associated with lower risk of adverse outcomes in patients with acute coronary syndromes (ACS). HYPOTHESIS:We explored this paradox in 84,429 patients with non-ST-segment elevation ACS in the Can Rapid Risk Stratification of Unstable ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20518
更新日期:2009-09-01 00:00:00
abstract::Atrial septal aneurysm in the otherwise normal heart is a very rare and usually asymptomatic condition. A midsystolic click was described as the only clinical manifestation so far. A low-pitched early-to-midsystolic acoustic phenomenon in a 39-year-old woman corresponding with maximal leftward motion of the aneurysmat...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960150713
更新日期:1992-07-01 00:00:00
abstract::In a series of 20 coronary excimer laser angioplasties, two patients presented with a peculiar type of malignant restenosis 6 and 8 weeks after a successful laser angioplasty procedure. One patient had a successful recanalization of an occluded left anterior descending (LAD) coronary artery and the second patient had ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960130606
更新日期:1990-06-01 00:00:00
abstract::Several classifications of antiarrhythmic drugs have appeared and all suffer considerable limitations. Recently a Task Force of the Working Group on Arrhythmias of the European Society of Cardiology proposed a novel classification of antiarrhythmic drugs (the so-called Sicilian Gambit) based on their action on the mos...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960170307
更新日期:1994-03-01 00:00:00
abstract:BACKGROUND:Small heart syndrome has previously been reported as neurocirculatory asthenia, associated with a small heart shadow on a chest roentgenogram. This is characterized as weakness or fatigue even after ordinary exertion, palpitation, dyspnea, and fainting, resembling patients with chronic fatigue syndrome (CFS)...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20227
更新日期:2008-07-01 00:00:00
abstract:BACKGROUND:Therapeutic angiogenesis, if combined with primary percutaneous transluminal coronary angioplasty or stent placement, could improve the outcome of patients suffering from multifocal coronary disease. HYPOTHESIS:Because of the concern that angiogenic growth factors might promote restenosis, we studied the ef...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960250606
更新日期:2002-06-01 00:00:00
abstract:BACKGROUND:Statins are the most widely used lipid lowering therapies which reduce cardiovascular risk, but are associated with muscular adverse events (AEs). Idiopathic inflammatory myopathies (IIM) are autoimmune diseases of the muscle with higher risk of cardiovascular disease. More data is needed regarding statin sa...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.23375
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Variations in the apolipoprotein E (apo E) gene may predict the incidence of coronary artery disease (CAD). However, the correlation between apo E polymorphism and the severity of CAD is still unclear. HYPOTHESIS:Apolipoprotein E polymorphism can predict CAD. METHODS:Used a case-case study of 213 Chinese a...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20703
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:QT interval shortens with exercise. Some of this shortening is due to an increase in heart rate, and some is due to other effects of exercise, probably mostly neuroendocrine effects. Data from subjects with cardiac transplants have suggested that non-heart rate-related changes in QT interval on exercise are ...
journal_title:Clinical cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/clc.4960220805
更新日期:1999-08-01 00:00:00
abstract::Several studies have investigated the role of physical fitness in atrial fibrillation (AF), but the results remain controversial. We aimed to estimate the association between physical fitness and risk of AF. We comprehensively retrieved data from the Cochrane Library, PubMed, and Embase databases until February 29, 20...
journal_title:Clinical cardiology
pub_type: 杂志文章,meta分析,评审
doi:10.1002/clc.22552
更新日期:2016-07-01 00:00:00
abstract::Thrombolytic therapy for prosthetic heart valve thrombosis has recently been receiving increased attention and is now frequently used an alternative to high-risk surgery. A case is presented describing a novel thrombolytic therapy regimen with emphasis on the role of transesophageal echocardiography in diagnosis and m...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960181117
更新日期:1995-11-01 00:00:00
abstract:BACKGROUND:Percutaneous interventions for aorto-ostial narrowing of native coronary arteries are challenging because of early elastic recoil after the procedure and the high restenosis rate. Cutting balloon angioplasty may reduce this complication. HYPOTHESIS:The purpose of the study was to evaluate the clinical outco...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20351
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to examine the influence of atrial fibrillation (AF) on the immediate and long-term outcome of patients undergoing balloon mitral valvotomy (BMV). HYPOTHESIS:Patients with atrial fibrillation fair poorly after balloon mitral valvotomy. METHODS:There were a total of 818 consecu...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.22068
更新日期:2012-12-01 00:00:00
abstract::Diffuse pulmonary hemorrhage has rarely been reported as a complication of thrombolytic therapy. Recently, two patients who developed this complication were observed at our institution. This diagnosis should be considered in any post-thrombolytic patient with respiratory distress, diffuse pulmonary infiltrates, and an...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960200321
更新日期:1997-03-01 00:00:00
abstract:BACKGROUND:Chronic stress is estimated to increase the risk of cardiovascular (CV) events two-fold. Although stress reduction has been linked to a reduction in CV events, little is known regarding its exact mechanism of benefit. HYPOTHESIS:Yoga and meditation will improve parameters of endothelial function. METHODS:W...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960290905
更新日期:2006-09-01 00:00:00
abstract::The 2011 Update of the American Heart Association's Cardiovascular Disease Prevention Guideline for Women is designed to help women and their physicians understand cardiovascular Disease (CVD) risks and undertake practical steps that are most effective in preventing heart disease and stroke. Defining a woman's risk st...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.20940
更新日期:2011-09-01 00:00:00
abstract::A community-wide study of patients hospitalized with acute myocardial infarction in metropolitan Baltimore was conducted to examine socio-demographic and clinical characteristics in association with ventricular fibrillation and cardiac arrest (VF/CA). Multivariate analyses revealed that variables significantly associa...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960040404
更新日期:1981-07-01 00:00:00
abstract:BACKGROUND:Preventive cardiology is currently not an American Board of Medical Specialties-recognized subspecialty. However, several programs offer non-accredited fellowships throughout the country. No source currently exists listing all available programs, and finding programs requires time-intensive search strategies...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.21959
更新日期:2012-05-01 00:00:00