Assessment of right ventricular diastolic filling in patients with coronary artery disease.

Abstract:

:To assess right ventricular (RV) diastolic filling in coronary artery disease (CAD), with special reference to the involved lesions of the coronary arteries and left ventricular (LV) systolic function, gated radionuclide ventriculography was performed at rest in 106 patients with single-vessel CAD. Based on the site of coronary arterial involvement, patients were classified into three groups: left anterior descending CAD, right CAD, and left circumflex CAD. Patients in each group were further subdivided according to normal or decreased LV ejection fraction, resulting in six groups. Seventeen normal subjects were examined as a control group. Time-activity and its first-derivative curves were computed for the right and left ventricles. RV systolic function was normally preserved in all six groups, even when LV systolic function was damaged severely. The ratio of peak RV filling rate to peak RV ejection rate was significantly decreased in all six groups compared with that in control subjects, indicating that RV filling was impaired in patients with CAD. The ratio was below the lower limit of normal in 14 (23%) of 62 patients with normal LV systolic function and in 13 (30%) of 44 patients with impaired LV systolic function. None of the control subjects showed a decreased ratio of peak RV filling rate to peak RV ejection rate. Thus, in patients with CAD, RV filling is impaired, which may be independent of the site of coronary arterial involvement and of the LV or RV systolic function.

journal_name

Clin Cardiol

journal_title

Clinical cardiology

authors

Yamagishi T,Matsuda Y,Nakatsuka M,Maeda J,Matsuda M

doi

10.1002/clc.4960161112

subject

Has Abstract

pub_date

1993-11-01 00:00:00

pages

816-22

issue

11

eissn

0160-9289

issn

1932-8737

journal_volume

16

pub_type

杂志文章
  • Association of coronary artery disease and valvular heart disease in Chile.

    abstract::This study analyzes the prevalence of coronary artery disease (CAD) among patients with rheumatic valvular heart disease (VHD) in Chile. Coronary angiography was performed in all patients referred to cardiac catheterization with VHD who were over age 50 years and who had angina or ECG signs of ischemia. A total of 100...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960060709

    authors: Marchant E,Pichard A,Casanegra P

    更新日期:1983-07-01 00:00:00

  • N-terminal pro-brain natriuretic peptide and short-term mortality in acute aortic dissection: A meta-analysis.

    abstract:BACKGROUND:Acute aortic dissection (AAD) is a life-threatening medical emergency that requires immediate diagnosis and rapid treatment. There is a paucity of data on the role of biomarkers in risk stratification of patients with AAD. HYPOTHESIS:N-terminal pro-brain natriuretic peptide (NT-proBNP) is associated with sh...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.23436

    authors: Vrsalovic M,Vrsalovic Presecki A,Aboyans V

    更新日期:2020-11-01 00:00:00

  • Cardiovascular risk stratification and cardiovascular risk factors associated with erectile dysfunction: assessing cardiovascular risk in men with erectile dysfunction.

    abstract::Cardiovascular risk factors are known to be associated with the presence of erectile dysfunction (ED), and ED is more common in men with cardiovascular disease (CVD). The Princeton Guidelines provide a strategy for assessing cardiac risk and planning a safe return to sexual activity. Men at low risk, who have fewer th...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,评审

    doi:10.1002/clc.4960271304

    authors: Barrett-Connor E

    更新日期:2004-04-01 00:00:00

  • Clinical implications of elevated serum interleukin-6, soluble CD40 ligand, metalloproteinase-9, and tissue inhibitor of metalloproteinase-1 in patients with acute ST-segment elevation myocardial infarction.

    abstract:BACKGROUND:Atherosclerosis is widely accepted as a chronic inflammatory disease. Research paid much attention to sensitive specific serum biomarkers for vulnerable plaques. The markers not only serve as diagnostic tools for the identification of patients with acute coronary syndrome (ACS), but also help us to identify ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.20254

    authors: Tan J,Hua Q,Gao J,Fan ZX

    更新日期:2008-09-01 00:00:00

  • Vitamin C preserves endothelial function in patients with coronary heart disease after a high-fat meal.

    abstract:BACKGROUND:It has been suggested that an oxidative mechanism is involved with the impaired endothelium-dependent vasodilatation that occurs after a high-fat meal. HYPOTHESIS:The study was undertaken to evaluate the effect of a single oral dose of vitamin C (2 g) on postprandially impaired endothelium-dependent vasodil...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4950250505

    authors: Ling L,Zhao SP,Gao M,Zhou QC,Li YL,Xia B

    更新日期:2002-05-01 00:00:00

  • The utility of Nitroderm TTS in angina pectoris: long-term treatment after switching from long-acting oral isosorbide dinitrate.

    abstract::Long-acting oral isosorbide dinitrate (ISDN) was replaced by Nitroderm TTS, and the utility of this drug in long-term treatment was assessed in 69 patients with angina pectoris. The frequency of attacks (p < 0.001) and the consumption of sublingual nitrate tablets (p < 0.01) were found to be significantly lower at 2 w...

    journal_title:Clinical cardiology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1002/clc.4960170107

    authors: Hayashi H,Ito T,Matsubara T,Watanabe T,Kuzuya F,Mizuno Y,Sotohata I,Fujinami T,Toyama J,Yamada K

    更新日期:1994-01-01 00:00:00

  • Acute coronary syndromes: selective vs early invasive strategies.

    abstract::Recommendations in the 2007 update of the American College of Cardiology/American Heart Association guidelines for patients with non-ST-elevation myocardial infarction (NSTEMI) provide considerable latitude regarding treatment choices and care pathways. Nevertheless, as accumulating evidence leads to increased recomme...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,评审

    doi:10.1002/clc.20671

    authors: Boden WE,Gupta V

    更新日期:2009-11-01 00:00:00

  • Atrial natriuretic peptide response to ionic and nonionic contrast left ventriculography.

    abstract::Atrial natriuretic peptide (ANP) levels were measured prior to and at 1 and 5 minutes postcontrast left ventriculography with an ionic contrast agent (diatrizoate), and a nonionic agent (iopamidol) and the results were compared. Since ionic contrast agents have been found to cause an increase in left ventricular end-d...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960130911

    authors: Salvucci TJ,Roman C,Cha SD,Maranhao V

    更新日期:1990-09-01 00:00:00

  • Transient biventricular apical ballooning: a unique presentation of the "broken heart".

    abstract::Transient left ventricular (LV) apical ballooning and normal epicardial coronary arteries are the hallmarks of Takotsubo cardiomyopathy. The syndrome is often triggered by emotional or physiologic stress, and its pathogenesis is poorly understood. Current proposals focus on elevated cathecolamines in association with ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.20065

    authors: Novak G,Kross K,Follmer K,Brofferio A,Shirani J

    更新日期:2007-07-01 00:00:00

  • Downregulation of peroxisome proliferator-activated receptor-gamma expression in hypertensive atrial fibrillation.

    abstract:BACKGROUND:Numerous evidence has suggested that either hypertension or atrial fibrillation (AF) is associated with systemic inflammation. Peroxisome proliferator-activated receptor-gamma (PPARgamma) has been proved to have anti-inflammatory effects and is implicated as a molecular pathway involved in many cardiovascula...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.20566

    authors: Chen X,Bing Z,He J,Jiang L,Luo X,Su Y,Kan B,Huang D,Wei Y

    更新日期:2009-06-01 00:00:00

  • Adjunctive low molecular weight heparin during fibrinolytic therapy in acute ST-segment elevation myocardial infarction: a meta-analysis of randomized control trials.

    abstract:BACKGROUND:Recent data suggests that low molecular weight heparins (LMWHs) may be superior to unfractionated heparin (UFH) as an adjunct to fibrinolytic therapy in patients with acute ST-segment elevation myocardial infarction (STEMI). HYPOTHESIS:We evaluated cardiac outcomes and the risk of major bleeding with LMWHs ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1002/clc.20432

    authors: Singh S,Bahekar A,Molnar J,Khosla S,Arora R

    更新日期:2009-07-01 00:00:00

  • Impaired left ventricular filling during ST-segment depression provoked by dipyridamole infusion in patients with syndrome X.

    abstract::The left ventricular filling and regional wall motion patterns were compared in 6 normal subjects, 20 patients with coronary artery disease, and 10 patients with syndrome X by means of Doppler and two-dimensional echocardiography during high-dose (0.9 mg/kg body weight in 10 min) dipyridamole infusion. During the proc...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960141009

    authors: Nadazdin A,Shahi M,Foale RA

    更新日期:1991-10-01 00:00:00

  • Left atrial activation and asymmetric anatomical remodeling in patients with atrial fibrillation: The relation between anatomy and function.

    abstract:BACKGROUND:Identifying patients with advanced left atrial (LA) remodeling before catheter ablation (CA) of atrial fibrillation (AF) is crucial. HYPOTHESIS:This study aimed to identify echocardiographic parameters associated with changes in anatomy and conduction properties of the left atrium (LA). METHODS:We examined...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.23515

    authors: Nedios S,Löbe S,Knopp H,Seewöster T,Heijman J,Crijns HJGM,Arya A,Bollmann A,Hindricks G,Dinov B

    更新日期:2021-01-01 00:00:00

  • Long-term results of combined cardiac contractility modulation and subcutaneous defibrillator therapy in patients with heart failure and reduced ejection fraction.

    abstract:BACKGROUND:Cardiac contractility modulation (CCM) is an electrical-device therapy for patients with heart failure with reduced ejection fraction (HFrEF). Patients with left ventricular ejection fraction (LVEF) ≤35% also have indication for an implantable cardioverter-defibrillator (ICD), and in some cases subcutaneous ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.22919

    authors: Röger S,Rudic B,Akin I,Shchetynska-Marinova T,Fastenrath F,Tülümen E,Liebe V,El-Battrawy I,Baumann S,Kuschyk J,Borggrefe M

    更新日期:2018-04-01 00:00:00

  • Chronic pretreatment of ACEI reduces no-reflow in patients with acute myocardial infarction treated with primary angioplasty.

    abstract:BACKGROUND:In animal models, pretreatment with angiotensin-converting enzyme inhibitor (ACEI) can reduce no-reflow. In the present study, we investigated whether pretreatment with ACEI may prevent no-reflow in patients who underwent primary coronary intervention for AMI. METHOD AND RESULTS:A total of 259 consecutive p...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.20060

    authors: Zhao JL,Yang YJ,Zhang YH,Pei WD,Sun YH,Chen JL,Gao RL

    更新日期:2007-03-01 00:00:00

  • Hemodynamics and myocardial oxygen metabolism of pulsus alternans in patients with dilative cardiomyopathy.

    abstract::The hemodynamic and myocardial energetic changes due to pulsus alternans were investigated by left and right heart catheterization and by oxygen consumption measurements in three patients with dilative cardiomyopathy. In all three patients, pulsus alternans developed after intravenous administration of the phosphodies...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960100506

    authors: Hasenfuss G,Holubarsch C,Heiss HW,Bonzel T,Funfack M,Revenaugh M,Meinertz T,Just H

    更新日期:1987-05-01 00:00:00

  • The measurement of lipids currently and 9 years ago--which is more associated with carotid intima-media thickness?

    abstract:BACKGROUND:Massive evidence supports that increase of lipids bring more risk of atherosclerosis. However, it is not clear if lipids measured a long time ago bear more risk than the current measurement. HYPOTHESIS:Lipids measured currently is more associated with carotid atherosclerosis than lipids measured long time a...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.22015

    authors: Huang Y,Yu X,Millican D,Wu L,Shi P,Lu M,Wu Y

    更新日期:2012-08-01 00:00:00

  • Association between psychiatric disorders and Marfan's syndrome in a large Sardinian family with a high prevalence of cardiac abnormalities.

    abstract:BACKGROUND:Marfan's syndrome is an inherited disorder of connective tissue associated with characteristic abnormalities of the skeletal, ocular, and cardiovascular systems. Marked clinical variability and age dependency of all manifestations of Marfan's syndrome may render the unequivocal diagnosis difficult in mildly ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960200311

    authors: Mercuro G,Carpiniello B,Ruscazio M,Zoncu S,Montisci R,Rudas N,Cherchi A

    更新日期:1997-03-01 00:00:00

  • The potential association between common comorbidities and severity and mortality of coronavirus disease 2019: A pooled analysis.

    abstract:BACKGROUD:The association between underlying comorbidities and cardiac injury and the prognosis in coronavirus disease 2019 (COVID-19) patients was assessed in this study. HYPOTHESIS:The underlying comorbidities and cardiac injury may be associated with the prognosis in COVID-19 patients. METHODS:A systematic search ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.23465

    authors: Luo L,Fu M,Li Y,Hu S,Luo J,Chen Z,Yu J,Li W,Dong R,Yang Y,Tu L,Xu X

    更新日期:2020-12-01 00:00:00

  • Total serum transforming growth factor-β1 is elevated in the entire spectrum of genetic aortic syndromes.

    abstract:BACKGROUND:Total serum transforming growth factor-beta 1 (tsTGF-β1) is increased in patients with Marfan syndrome (MFS), but it has not been assessed in thoracic aortic aneurysm and dissection (TAAD), Loeys-Dietz syndrome (LDS), and bicuspid aortic valve disease (BAVD). HYPOTHESIS:tsTGF-β1 is increased in genetic aort...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.22320

    authors: Hillebrand M,Millot N,Sheikhzadeh S,Rybczynski M,Gerth S,Kölbel T,Keyser B,Kutsche K,Robinson PN,Berger J,Mir TS,Zeller T,Blankenberg S,von Kodolitsch Y,Goldmann B

    更新日期:2014-11-01 00:00:00

  • Hypercholesterolemia paradox in relation to mortality in acute coronary syndrome.

    abstract:BACKGROUND:Hypercholesterolemia is a risk factor for coronary artery disease, yet is associated with lower risk of adverse outcomes in patients with acute coronary syndromes (ACS). HYPOTHESIS:We explored this paradox in 84,429 patients with non-ST-segment elevation ACS in the Can Rapid Risk Stratification of Unstable ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.20518

    authors: Wang TY,Newby LK,Chen AY,Mulgund J,Roe MT,Sonel AF,Bhatt DL,DeLong ER,Ohman EM,Gibler WB,Peterson ED

    更新日期:2009-09-01 00:00:00

  • Late recovery in peripartum cardiomyopathy.

    abstract::Full recovery occurred after 15 months of severe congestive heart failure in a patient with peripartum cardiomyopathy. Clinical improvement was noted when propranolol was added to conventional therapy. ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960030211

    authors: Moreyra AE,Kostis JB,Amendo M

    更新日期:1980-08-01 00:00:00

  • Effects of exercise on plasma viscosity in athletes and sedentary normal subjects.

    abstract::To assess the immediate and long-term effects of exercise on factors regulating blood flow, we measured plasma viscosity (eta p) and plasma renin activity (PRA) in 17 trained runners and 16 sedentary healthy subjects before and 10 min after graded treadmill exercise. Resting eta p was lower in runners primarily becaus...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960040405

    authors: Letcher RL,Pickering TG,Chien S,Laragh JH

    更新日期:1981-07-01 00:00:00

  • Genetic diagnosis of familial hypercholesterolemia is associated with a premature and high coronary heart disease risk.

    abstract:BACKGROUND:Familial hypercholesterolemia (FH) is a common autosomal dominant disease associated with premature coronary heart disease (CHD). Studies tend to show that patients with FH associated with an identified mutation (mutation+ FH) are at higher risk than patients without an identified mutation (mutation- FH). We...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.22881

    authors: Séguro F,Rabès JP,Taraszkiewicz D,Ruidavets JB,Bongard V,Ferrières J

    更新日期:2018-03-01 00:00:00

  • INVEST: results of combined strategies to control blood pressure.

    abstract::The treatment of hypertension continues to be challenging due to the lack of understanding regarding underlying modulators of blood pressure as well as co-existing conditions such as atherosclerosis and diabetes. This has led to uncertainty regarding treatment strategy and intensity. The INternational VErapamil SR/tra...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960241705

    authors: Kolloch RE

    更新日期:2001-11-01 00:00:00

  • Outcomes associated with preoperative use of extracorporeal membrane oxygenation in children undergoing heart operation for congenital heart disease: a multi-institutional analysis.

    abstract:BACKGROUND:There are very sparse data on patient outcomes related to the use of extracorporeal membrane oxygenation (ECMO) prior to heart operation in children with congenital heart disease. This study was designed to evaluate this association using the Pediatric Health Information System (PHIS) database. HYPOTHESIS:W...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,多中心研究

    doi:10.1002/clc.22358

    authors: Gupta P,Robertson MJ,Beam BW,Rettiganti M

    更新日期:2015-02-01 00:00:00

  • The clinical distinction between regional postinfarction pericarditis and other causes of postinfarction chest pain: ancillary observations regarding the effect of lytic therapy upon the frequency of postinfarction pericarditis, postinfarction angina, and

    abstract::Recently two types of atypical T-wave evolution were recognized as electrocardiographic (ECG) markers of regional postinfarction pericarditis. The sensitivity and specificity of these changes for this condition were 100 and 77%, respectively. The major purpose of this investigation is to show how these ECG changes can...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960170903

    authors: Oliva PB,Hammill SC

    更新日期:1994-09-01 00:00:00

  • Relationships between heart rate variability, functional capacity, and left ventricular function following myocardial infarction: an evaluation after one week and six months.

    abstract:BACKGROUND:Relationships between heart rate (HR) variability and different prognostic markers such as ejection fraction, functional capacity, and patency of the infarct-related artery, as well as the comparison of their time courses are not fully elucidated. HYPOTHESIS:The aim of study was to assess prospectively the ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960240411

    authors: Monmeneu JV,Chorro FJ,Bodí V,Sanchis J,Llácer A,García-Civera R,Ruiz R,Sanjuán R,Burguera M,López-Merino V

    更新日期:2001-04-01 00:00:00

  • Management of patients after thrombolytic therapy for acute myocardial infarction.

    abstract::The coronary artery thrombus that causes acute myocardial infarction can be lysed, and reperfusion can be achieved, in the first few hours after infarction. However, the infarct vessel will reocclude in 15-30% of patients, and this event is frequently associated with pain, reinfarction, arrhythmias, or death. The risk...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960080902

    authors: Goldberg RK,Levine S,Fenster PE

    更新日期:1985-09-01 00:00:00

  • Taking cardiology clinical trials to the next level: A call to action.

    abstract::Physicians previously perceived heart disease to be a man's disease; yet, since 1984, more women have died of ischemic heart disease. Because women who develop obstructive coronary heart disease and heart failure tend to do so 10 years later than men, cardiology clinical trials that use arbitrary age cutoffs or exclus...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,评审

    doi:10.1002/clc.22907

    authors: Clayton JA,Arnegard ME

    更新日期:2018-02-01 00:00:00