Abstract:
:Recommendations in the 2007 update of the American College of Cardiology/American Heart Association guidelines for patients with non-ST-elevation myocardial infarction (NSTEMI) provide considerable latitude regarding treatment choices and care pathways. Nevertheless, as accumulating evidence leads to increased recommendations for early invasive strategies, more patients are likely to receive care that falls short of recommendations. While tailoring pharmacotherapy to optimize the risk/benefit ratio for individual patients remains essential, it becomes increasingly important that care paradigms be prospectively defined. To facilitate this goal, we examined key differences between the 2002 and 2007 guidelines and explored data underlying changed recommendations for periprocedural pharmacotherapy.
journal_name
Clin Cardioljournal_title
Clinical cardiologyauthors
Boden WE,Gupta Vdoi
10.1002/clc.20671subject
Has Abstractpub_date
2009-11-01 00:00:00pages
621-6issue
11eissn
0160-9289issn
1932-8737journal_volume
32pub_type
杂志文章,评审abstract::The optimal approach to electrical cardioversion of atrial fibrillation includes appropriate patient selection, anticoagulation, careful selection and monitoring of antiarrhythmic therapy, and proper electrical cardioversion technique. The optimal technique requires the use of metal electrodes, with one electrode of a...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960170207
更新日期:1994-02-01 00:00:00
abstract::The effects of heparin were studied in a group of 42 patients with preinfarction angina (PA) and acute myocardial infarction (AMI) whose plasma fibrinogen was increased. Plasma fibrinogen was measured by the turbidimetric method in timol turbidimetric units. Statistically significant results proved that heparin reduce...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960060504
更新日期:1983-05-01 00:00:00
abstract::The pacemaker syndrome refers to symptoms and signs in the pacemaker patient caused by inadequate timing of atrial and ventricular contractions. The lack of normal atrioventricular synchrony may result in decreased cardiac output and venous "cannon A waves." A sudden increase in atrial pressure at the onset of asynchr...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960140410
更新日期:1991-04-01 00:00:00
abstract:BACKGROUND:The electrocardiogram (ECG) is valuable for the identification of prior myocardial infarction (MI) in individuals participating in epidemiologic studies or undergoing screening examinations. Although the Minnesota Code, a set of criteria for the interpretation of ECGs in such situations, is commonly used to ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960270212
更新日期:2004-02-01 00:00:00
abstract:BACKGROUND:Inflammation is a key factor in the development of atherosclerotic disease and acute coronary syndromes (ACS). The P2Y(12) receptor antagonists ticagrelor (AZD6140) and clopidogrel may have anti-inflammatory effects. The objective of this analysis from the Dose Confirmation Study Assessing Anti-Platelet Effe...
journal_title:Clinical cardiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/clc.20732
更新日期:2010-04-01 00:00:00
abstract::We have studied the changes induced in atherosclerotic arteries by a CO2 laser beam delivered through a silver halide optical fiber. We found that the crater depth and diameter correlate with the total energy delivered and with the mode of delivery. Short-duration high-power pulses caused shallower and narrower crater...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960090302
更新日期:1986-03-01 00:00:00
abstract::Paradoxical interventricular septal motion with right ventricular dilatation has been considered the hallmark of right ventricular volume overload. We report a 43-year-old woman with severe pulmonary hypertension due to pulmonary veno-occlusive disease who exhibited these echocardiographic abnormalities. Right ventric...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960081111
更新日期:1985-11-01 00:00:00
abstract:BACKGROUND:Advanced age remains one of the principal determinants of mortality in patients with acute myocardial infarction (AMI). HYPOTHESIS:The aim of this study was to determine the in-hospital outcome of elderly (> 75 years) patients with AMI who were admitted to hospitals participating in the national MITRA (Maxi...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960231109
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND:Little is known about the relationship of body fluid status with the levels and fluctuations of B-type natriuretic peptide (BNP) over the long-term. HYPOTHESIS:If BNP is to become useful for monitoring of patients with chronic heart failure (HF), the levels should reliably reflect both decompensation and im...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960291008
更新日期:2006-10-01 00:00:00
abstract::The occurrence and influence of coronary collateral circulation and obstruction of the supplying coronary arteries on left ventricular contractility, prevalence of myocardial infarction, and bicycle exercise ergometer test were studied in a random sample of 286 patients with angiographically documented coronary artery...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960140206
更新日期:1991-02-01 00:00:00
abstract::Although optimal pharmacological therapy for heart failure with reduced ejection fraction (HFrEF) is carefully scripted by treatment guidelines, many eligible patients are not treated with guideline-directed medical therapy (GDMT) in clinical practice. We designed a strategy for remote optimization of GDMT on a popula...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.23291
更新日期:2020-01-01 00:00:00
abstract::Rapid assessment of patients presenting with acute chest pain is essential, in order to distinguish between those who have a life-threatening condition, such as myocardial infarction or unstable angina, and the substantial proportion who do not have an acute coronary syndrome. It is thus of vital importance that relia...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960231306
更新日期:2000-01-01 00:00:00
abstract::Subaortic stenosis has been described with increasing frequency as an ominous feature of atrioventricular septal defect (AVSD), especially following surgical correction of the anomaly in non-Down's syndrome patients. In order to study the surgical anatomy of the left ventricular outflow tract in this malformation, 48 ...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960140611
更新日期:1991-06-01 00:00:00
abstract::The prevalence of interatrial block (IAB) is high in the elderly, particularly in those with heart disease. Despite this high prevalence-and the association of IAB with the risk of atrial fibrillation (AF), stroke, and cognitive decline-little information exists about the prognosis of older patients with IAB. P-wave d...
journal_title:Clinical cardiology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1002/clc.22647
更新日期:2017-04-01 00:00:00
abstract::Many patients with coronary artery disease treated by percutaneous transluminal coronary angioplasty (PTCA) have a history of previous myocardial injury resulting in a reduced left ventricular ejection fraction (EF). The effects of successful PTCA on myocardial perfusion and left ventricular function in these patients...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960120504
更新日期:1989-05-01 00:00:00
abstract:BACKGROUND:Advanced practice providers (APPs) can fill care gaps created by physician shortages and improve adherence/compliance with preventive ASCVD interventions. HYPOTHESIS:APPs utilizing guideline-based algorithms will more frequently escalate ASCVD risk factor therapies. METHODS:We retrospectively reviewed data...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.22963
更新日期:2018-06-01 00:00:00
abstract::Pregnant patients with mechanical prosthetic heart valves pose a great problem for medical management. The problem is even greater in a pregnant woman with mechanical valve thrombosis. This article describes a pregnant woman with prosthetic mitral valve thrombosis who had a successful fibrinolytic treatment. ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20637
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:The present European guidelines suggest a diagnostic electrophysiological (EP) study to determine indication for cardiac pacing in patients with bundle branch block and unexplained syncope. We evaluated the prognostic relevance of an EP study for mortality and the development of permanent complete atrioventr...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.22700
更新日期:2017-08-01 00:00:00
abstract::Pathophysiology of malignant hypertension, of which underlying disease was essential hypertension (EHT) in 33 cases and chronic glomerulonephritis (CGN) in 26 cases, was studied with reference to the renin-angiotensin system. Plasma renin activity (PRA) was significantly higher in the EHT than in the CGN group, and an...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960100911
更新日期:1987-09-01 00:00:00
abstract::In a family affected by arrhythmogenic right ventricular cardiomyopathy (ARVC) the familial occurrence was investigated. All 14 members of two generations were investigated carefully, and only 2 (father and one son) members were affected. Both subjects had a massive form of the disease with relevant ventricular arrhyt...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960150314
更新日期:1992-03-01 00:00:00
abstract::In order to test the comparative sensitivities of first-pass radionuclide and digital subtraction ventriculography in detecting wall motion abnormalities during exercise, 29 patients referred for coronary angiography were submitted to both types of stress ventriculograms. Resting and exercise ventriculograms by both t...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960090906
更新日期:1986-09-01 00:00:00
abstract::Hospitals typically use Center for Medicare and Medicaid Services' (CMS) Hospital Readmission Reduction Program (HRRP) administrative reports as the standard of heart failure (HF) admission quantification. We aimed to evaluate the HF admission population identified by CMS HRRP definition of HF hospital admissions comp...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.22711
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Intravenous inotropic intervention in congestive heart failure is generally associated with a poor prognosis and is largely used as a "bridge" to mechanical support or heart transplantation. HYPOTHESIS:We hypothesized that the inotropic support afforded by dobutamine may serve as a bridge to the introductio...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960240311
更新日期:2001-03-01 00:00:00
abstract::Cardiac anatomy and rhythm were evaluated in the fetuses of 18 pregnant women (between 20 and 42 weeks of gestation) referred because of abnormal fetal heart rate or rhythm. Utilizing a 3 MHz two-dimensional scan head with M-mode capability, M-mode recordings were obtained at paper speeds of 50 and 100 mm/s from 16 fe...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960080102
更新日期:1985-01-01 00:00:00
abstract::The safety of quinapril hydrochloride, a new nonsulfhydryl angiotensin-converting enzyme (ACE) inhibitor with an intermediate duration of action, has been evaluated in 3,031 patients with hypertension and congestive heart failure (CHF) and has been compared with other ACE inhibitors. A comparison of double-blind studi...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960131408
更新日期:1990-06-01 00:00:00
abstract::Three cases are presented where acute myocardial infarction occurred in young individuals after an episode of heavy alcohol intake. Subsequent coronary arteriograms demonstrated normal coronary arteries. Several mechanisms by which acute ethanol intoxication might precipitate myocardial infarction are discussed. To ou...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960050707
更新日期:1982-07-01 00:00:00
abstract::A patient is presented who has mitral valve prolapse and syndactyly of the hands. This combination of findings has not been previously reported, but is consistent with one theory of the development of mitral valve prolapse. ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960050306
更新日期:1982-03-01 00:00:00
abstract::Paravalvular regurgitation (PVR) remains one of the drawbacks of transcatheter aortic valve implantation (TAVI). Details of percutaneous closure (PCC) of PVR after TAVI remain obscure. We aimed to explore the patient characteristics, procedural details, closure devices used, and outcomes of PCC after TAVI. A systemati...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.22569
更新日期:2016-10-01 00:00:00
abstract::Peripartum cardiomyopathy (PPCM) is a rare cause of heart failure. It is defined as cardiomyopathy that develops in the last month of pregnancy or within 5 months of the postpartum period without an identifiable cause. We conducted a systematic review of literature of prospective studies with a focus on echocardiograp...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.22932
更新日期:2018-05-01 00:00:00
abstract::Cardiac troponins (CTn) are the most sensitive and specific biochemical markers of myocardial injury and risk stratification. The assay for troponin T (cTnI) is standardized, and results obtained from different institutions are comparable. This is not the case with troponin I (cTnT), and clinicians should be aware tha...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.20445
更新日期:2009-01-01 00:00:00